Terfamex Uses

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What is Terfamex?

Terfamex (Terfamex) is a stimulant similar to an amphetamine. Terfamex is an appetite suppressant that affects the central nervous system.

Terfamex is used together with diet and exercise to treat obesity (overweight) in people with risk factors such as high blood pressure, high cholesterol, or diabetes.

Terfamex may also be used for purposes not listed in this medication guide.

Terfamex indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Terfamex is indicated as a short-term (a few weeks) adjunct in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity for patients with an initial body mass index greater than or equal to 30 kg/m2, or greater than or equal to 27 kg/m2 in the presence of other risk factors (e.g., controlled hypertension, diabetes, hyperlipidemia).

Below is a chart of body mass index (BMI) based on various heights and weights.

BMI is calculated by taking the patient’s weight, in kilograms (kg), divided by the patient’s height, in meters (m), squared. Metric conversions are as follows: pounds ÷ 2.2 = kg; inches x 0.0254 = meters.

Height (feet, inches)

BODY MASS INDEX (BMI), kg/m2
Weight

(pounds)

5’0” 5’3” 5’6” 5’9” 6’0” 6’3”
140 27 25 23 21 19 18
150 29 27 24 22 20 19
160 31 28 26 24 22 20
170 33 30 28 25 23 21
180 35 32 29 27 25 23
190 37 34 31 28 26 24
200 39 36 32 30 27 25
210 41 37 34 31 29 26
220 43 39 36 33 30 28
230 45 41 37 34 31 29
240 47 43 39 36 33 30
250 49 44 40 37 34 31

The limited usefulness of agents of this class, including Terfamex, should be measured against possible risk factors inherent in their use such as those described below.

How should I use Terfamex?

Use Terfamex orally disintegrating tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Terfamex orally disintegrating tablets.

Uses of Terfamex in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Terfamex is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who are obese or have weight-related medical problems. Losing weight and keeping it off can lessen the many health risks that come with obesity, including heart disease, diabetes, high blood pressure, and a shorter life.

It is not known how this medication helps people to lose weight. It may work by decreasing your appetite, increasing the amount of energy used by your body, or by affecting certain parts of the brain. This medication is an appetite suppressant and belongs to a class of drugs called sympathomimetic amines.

How to use Terfamex

Take this medication by mouth as directed by your doctor, usually once a day, 1 hour before breakfast or 1 to 2 hours after breakfast. If needed, your doctor may adjust your dose to take a small dose up to 3 times a day. Carefully follow your doctor's instructions. Taking this medication late in the day may cause trouble sleeping (insomnia).

If you are using sustained-release capsules, the dose is usually taken once a day before breakfast or at least 10 to 14 hours before bedtime. Swallow the medication whole. Do not crush or chew sustained-release capsules. Doing so can release all of the drug at once, increasing the risk of side effects.

If you are using the tablets made to dissolve in the mouth, the dose is usually taken once a day in the morning, with or without food. First, dry your hands before handling the tablet. Place your dose on top of the tongue until it dissolves, then swallow it with or without water.

The dosage is based on your medical condition and response to therapy. Your doctor will adjust the dose to find the best dose for you. Use this medication regularly and exactly as prescribed in order to get the most benefit from it. To help you remember, take it at the same time(s) each day.

This medication is usually taken for only a few weeks at a time. It should not be taken with other appetite suppressants. The possibility of serious side effects increases with longer use of this medication and use of this drug along with certain other diet drugs.

This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as depression, severe tiredness) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions right away.

Rarely, abnormal drug-seeking behavior (addiction) is possible with this medication. Do not increase your dose, take it more frequently, or use it for a longer time than prescribed. Properly stop the medication when so directed.

This medication may stop working well after you have been taking it for a few weeks. Talk with your doctor if this medication stops working well. Do not increase the dose unless directed by your doctor. Your doctor may direct you to stop taking this medication.

Terfamex description

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A central nervous system stimulant and sympathomimetic with actions and uses similar to those of dextroamphetamine. It has been used most frequently in the treatment of obesity. [PubChem]. Some common brand names for Terfamex are Terfamex® and Terfamex™. Terfamex is also available in combination medications such as Qsymia®.

Terfamex dosage

Exogenous Obesity

Dosage should be individualized to obtain an adequate response with the lowest effective dose.

The usual adult dose is one tablet as prescribed by the physician, administered in the morning, with or without food. Terfamex is not recommended for use in pediatric patients less than or equal to 16 years of age.

Late evening medication should be avoided because of the possibility of resulting insomnia.

With dry hands, gently remove the Terfamex (Terfamex hydrochloride ODT) tablet from the bottle. Immediately place the Terfamex tablet on top of the tongue where it will dissolve, then swallow with or without water.

How supplied

Dosage Forms And Strengths

Orally disintegrating tablets (ODT) containing 15 mg, 30 mg, or 37.5 mg Terfamex hydrochloride (equivalent to 12 mg, 24 mg, or 30 mg Terfamex base, respectively). The tablets are not scored. The 15 mg ODT is a yellow with blue spots round tablet embossed with AX4 on one side. The 30 mg ODT is a yellow round tablet embossed with AX7 on one side. The 37.5 mg ODT is a white with blue spots round tablet embossed with AX8 on one side.

Storage And Handling

Available as orally disintegrating tablets (ODT) containing 15 mg, 30 mg, or 37.5 mg of Terfamex hydrochloride (equivalent to 12 mg, 24 mg, or 30 mg Terfamex base, respectively). The tablets are not scored. The 15 mg ODT is a yellow with blue spots round tablet embossed with AX4 on one side. The 30 mg ODT is a yellow round tablet embossed with AX7 on one side. The 37.5 mg ODT is a white with blue spots round tablet embossed with AX8 on one side.

Terfamex is available as described in Table 2.

Table 2: Terfamex

Orally Disintegrating Tablet Presentations

Tablet Strength Tablet Color/Shape Tablet Markings NDC Code
15 mg Round, embossed tablets Yellow with blue spots AX4 on one side NDC:24090 720
30 mg Round, embossed tablets Yellow AX7 on one side NDC:24090 721
37.5 mg Round, embossed tablets White with blue spots AX8 on one side NDC:24090 722

Terfamex 15 mg, 30 mg, and 37.5 mg ODT are packaged in bottles of 30.

Store at 20° to 25°C (68° to 77°F).

Dispense in a tight container as defined in the USP, with a child-resistant closure (as required).

Keep out of the reach of children.

Manufactured for Akrimax Pharmaceuticals, LLC Cranford, NJ 07016. by: Alpex Pharma SA, Lugano, Switzerland. Marketed and Distributed by: Akrimax Pharmaceuticals, LLC Cranford, NJ 07016. Revised: 06/2013

Terfamex interactions

See also:
What other drugs will affect Terfamex?

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Monoamine Oxidase Inhibitors

Use of Terfamex® is contraindicated during or within 14 days following the administration of monoamine oxidase inhibitors because of the risk of hypertensive crisis.

Alcohol

Concomitant use of alcohol with Terfamex® may result in an adverse drug reaction.

Insulin And

Oral Hypoglycemic Medications

Requirements may be altered.

Adrenergic Neuron Blocking Drugs

Terfamex® may decrease the hypotensive effect of adrenergic neuron blocking drugs.

Drug Abuse And Dependence

Controlled Substance

Terfamex is a Schedule IV controlled substance.

Abuse

Terfamex is related chemically and pharmacologically to the amphetamines. Amphetamines and other stimulant drugs have been extensively abused and the possibility of abuse of Terfamex should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program.

Dependence

Abuse of amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction. There are reports of patients who have increased the dosage of these drugs to many times than recommended. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity and personality changes. A severe manifestation of chronic intoxication is psychosis, often clinically indistinguishable from schizophrenia.

Terfamex side effects

See also:
What are the possible side effects of Terfamex?

Applies to Terfamex: oral capsule, oral capsule extended release, oral tablet, oral tablet disintegrating

In addition to its needed effects, some unwanted effects may be caused by Terfamex (the active ingredient contained in Terfamex). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking Terfamex:

Rare

Incidence not known:

Minor Side Effects

Some of the side effects that can occur with Terfamex may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Incidence not known:

Terfamex contraindications

See also:
What is the most important information I should know about Terfamex?

Weight loss during pregnancy can harm an unborn baby, even if you are overweight. Do not use Terfamex if you are pregnant.

Do not use Terfamex if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Taking Terfamex together with other diet medications such as fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can cause a rare fatal lung disorder called pulmonary hypertension. Do not take Terfamex with any other diet medications without your doctor's advice.

Terfamex may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Drinking alcohol can increase certain side effects of Terfamex.

Terfamex is only part of a complete program of treatment that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

Terfamex may be habit-forming and should be used only by the person it was prescribed for. Never share Terfamex with another person, especially someone with a history of drug abuse or addiction. Keep track of the amount of medicine used from each new bottle. Terfamex is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Do not stop using Terfamex suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using Terfamex.



Active ingredient matches for Terfamex:

Phentermine in Costa Rica, Dominican Republic, El Salvador, Guatemala, Honduras, Mexico, Panama.


Unit description / dosage (Manufacturer)Price, USD
Capsule; Oral; Phentermine Hydrochloride 15 mg
Capsule; Oral; Phentermine Hydrochloride 30 mg
Capsules; Oral; Phentermine Hydrochloride 15 mg
Capsules; Oral; Phentermine Hydrochloride 30 mg

List of Terfamex substitutes (brand and generic names):

Capsule; Oral; Phentermine Hydrochloride 30 mg
Capsules; Oral; Phentermine Hydrochloride 30 mg
Capsule; Oral; Phentermine Resin Complex 15 mg
Capsules; Oral; Phentermine Resin Complex 15 mg
RAZIN 10MG TABLET 1 strip / 10 tablets each (Shine Pharmaceuticals Ltd)$ 0.52
Razin 10mg Tablet (Shine Pharmaceuticals Ltd)$ 0.05
Redusa 15 mg x 500's
Redusa 25 mg x 500's
Redusa Forte 35 mg x 500's
Capsules; Oral; Phentermine Hydrochloride 15 mg
Capsules; Oral; Phentermine Hydrochloride 25 mg
Suprenza tablet, orally disintegrating 15 mg/1 (Akrimax Pharmaceuticals, LLC (US))
Suprenza tablet, orally disintegrating 30 mg/1 (Akrimax Pharmaceuticals, LLC (US))
Suprenza tablet, orally disintegrating 37.5 mg/1 (Akrimax Pharmaceuticals, LLC (US))
Tablet; Oral; Phentermine Hydrochloride 8 mg (Patson Laboratories Pvt.Ltd.)
Tablets; Oral; Phentermine Hydrochloride 8 mg (Patson Laboratories Pvt.Ltd.)
Tora 100+500 Tablet (Patson Laboratories Pvt.Ltd.)$ 0.04
TORA TABLET 1 strip / 10 tablets each (Patson Laboratories Pvt.Ltd.)$ 0.83
Tora 10mg Tablet (Patson Laboratories Pvt.Ltd.)$ 0.08
Umine 10 mg x 1000's

References

  1. PubChem. "phentermine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "phentermine". http://www.drugbank.ca/drugs/DB00191 (accessed September 17, 2018).
  3. DTP/NCI. "phentermine: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Terfamex are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Terfamex. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


1 consumer reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Terfamex drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users%
Not expensive1
100.0%


4 consumers reported time for results

To what extent do I have to use Terfamex before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 1 day and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Terfamex. To get the time effectiveness of using Terfamex drug by other patients, please click here.
Users%
1 day2
50.0%
3 month1
25.0%
> 3 month1
25.0%


16 consumers reported age

Users%
30-456
37.5%
16-296
37.5%
46-604
25.0%


Consumer reviews


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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