Thiocolchicoside Uses

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Thiocolchicoside indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Bromazepam is an intermediate-acting tranquiliser, prescribed for the treatment of moderate to severe anxiety and panic disorders and for the short-term treatment of insomnia. Unlike the benzodiazepine alprazolam it does not possess any antidepressant qualities.

In low doses it diminishes anxiety and tension. In higher doses the sedative and muscle-relaxant properties appear.

Uses of Thiocolchicoside in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Thiocolchicoside is used (as an additive treatment) for relieving painful stiffness or constriction in various diseases of the muscles, nerves, spine and the joints.

Thiocolchicoside description

Thiocolchicoside is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine receptor antagonist with similar potency and nicotinic acetylcholine receptors to a much lesser extent. It has powerful convulsant activity and should not be used in seizure-prone individuals.

Thiocolchicoside dosage

Oral

Muscle spasms

Adult: Initially, 16 mg daily.

Intramuscular

Muscle spasms

Adult: Up to 8 mg daily.

Thiocolchicoside interactions

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LEXOTAN undergoes hepatic microsomal oxidation via the cytochrome P450 liver enzymes.

Therefore, caution should be taken in patients taking medicines that inhibit the P450 liver enzymes (e.g. azole antifungals, macrolide antibiotics, HIV protease inhibitors, calcium channel blocking agents).

LEXOTAN undergoes oxidative metabolism and, consequently, may interact with disulfiram or cimetidine resulting in increased plasma levels of LEXOTAN. Patients should be observed closely for evidence of enhanced benzodiazepine response during concomitant treatment with either disulfiram or cimetidine; some patients may require a reduction in benzodiazepine dosage.

The benzodiazepines, including LEXOTAN, produce additive CNS depressant effects when coadministered with other medications which themselves produce CNS depression e.g. barbiturates, alcohol, sedatives, antidepressants, hypnotics, anxiolytics, phenothiazines and other antipsychotics,

skeletal muscle relaxants, antihistamines, narcotic analgesics and anaesthetics.

Alcohol should be avoided in patients receiving LEXOTAN.

In the case of narcotic analgesics enhancement of euphoria may also occur, leading to an increase in psychic drug dependence.

The anticholinergic effects of atropine and similar medicines, antihistamines and antidepressants may be potentiated.

Interactions have been reported between some benzodiazepines and anticonvulsants, with changes in the serum concentration of the benzodiazepine or anticonvulsant. It is recommended that patients be observed for altered responses when benzodiazepines and anticonvulsants are prescribed together and that serum level monitoring of the anticonvulsant be performed more frequently.

Interference with Clinical, Laboratory or Other Tests:

Minor EEG changes, usually low voltage fast activity, of no known clinical significance, has been

reported with benzodiazepine administration.

Thiocolchicoside side effects

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Photosensitivity reactions,Thiocolchicoside Tablets and capsules may cause irritation of the digestive system. Therefore, your doctor Thiocolchicoside tablets / capsules during your use of gastric protective drugs may tell you to use. Follow your doctor’s instructions.

If diarrhea occurs In such a situation should reduce your dosage. Thiocolchicoside rest, physical therapy and other measures, including pain relief is only one part of the complete treatment program.

Avoid drinking alcohol. Alkol Thiocolchicoside alcohol may increase some side effects.

Thiocolchicoside contraindications

If you are allergic to any drugs, or if you have any of the following conditions inform your doctor before using Thiocolchicoside:

kidney disease;

bleeding problems; The drugs prevent blood clotting [warfarin sodium ( Coumadin )] utilization.

Active ingredient matches for Thiocolchicoside:

Thiocolchicoside


Unit description / dosage (Manufacturer)Price, USD
Tablet; Oral; Thiocolchicoside 4 mg

List of Thiocolchicoside substitutes (brand and generic names):

THIOCHY-MR tab 10's (Malody)
4 mg x 10's (Medico Health Care)$ 1.41
8 mg x 10's (Medico Health Care)$ 2.78
Thiofact 4mg CAP / 10 (Medico Health Care)$ 1.41
Thiofact 8mg CAP / 10 (Medico Health Care)$ 2.78
Thiofact 8 mg Tablet (Medico Health Care)$ 0.28
Thiofact 4 mg Tablet (Medico Health Care)$ 0.14
THIOFACT cap 4 mg x 10's (Medico Health Care)$ 1.41
THIOFACT cap 8 mg x 10's (Medico Health Care)$ 2.78
Thiofact 4mg CAP / 10 (Medico Health Care)$ 1.41
Thiofact 8mg CAP / 10 (Medico Health Care)$ 2.78
4 mg x 100's (Intra Labs)$ 25.40
8 mg x 100's (Intra Labs)$ 42.86
Thiogesic 4mg TAB / 100 (Intra Labs)$ 25.40
Thiogesic 8mg TAB / 100 (Intra Labs)$ 42.86
THIOGESIC cap 4 mg x 10's (Intra Labs)$ 1.90
THIOGESIC cap 8 mg x 10's (Intra Labs)$ 3.17
Thiogesic 4mg TAB / 100 (Intra Labs)$ 25.40
Thiogesic 8mg TAB / 100 (Intra Labs)$ 42.86
Thiomed 50 mg x 1, 000's (Medifive)
Thiomed 100 mg x 1, 000's (Medifive)
THIOMEP tab 4 mg x 10's (Pax Healthcare)
Thiomin 4mg CAP / 10x10 (Intra (Intra Life))$ 14.29
THIOMIN cap 4 mg x 10's (Intra (Intra Life))$ 1.43

References

  1. PubChem. "Thiocolchicoside". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Thiocolchicoside". http://www.drugbank.ca/drugs/DB11582 (accessed September 17, 2018).
  3. MeSH. "MeSH Tree: MeSH (Medical Subject Headings) is the NLM controlled vocabulary thesaurus used for indexing articles for PubMed.". http://www.nlm.nih.gov/mesh/meshhome... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Thiocolchicoside are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Thiocolchicoside. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

1 consumer reported useful

Was the Thiocolchicoside drug useful in terms of decreasing the symptom or the disease?
According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
Users%
Not useful1
100.0%


2 consumers reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Thiocolchicoside drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users%
Not expensive1
50.0%
Expensive1
50.0%


1 consumer reported time for results

To what extent do I have to use Thiocolchicoside before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 1 day and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Thiocolchicoside. To get the time effectiveness of using Thiocolchicoside drug by other patients, please click here.
Users%
1 day1
100.0%


9 consumers reported age

Users%
16-292
22.2%
6-152
22.2%
30-452
22.2%
> 602
22.2%
1-51
11.1%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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