Thiomin Uses

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Thiomin indications

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Bromazepam is an intermediate-acting tranquiliser, prescribed for the treatment of moderate to severe anxiety and panic disorders and for the short-term treatment of insomnia. Unlike the benzodiazepine alprazolam it does not possess any antidepressant qualities.

In low doses it diminishes anxiety and tension. In higher doses the sedative and muscle-relaxant properties appear.

Uses of Thiomin in details

Thiomin is used (as an additive treatment) for relieving painful stiffness or constriction in various diseases of the muscles, nerves, spine and the joints.

Thiomin description

Thiomin is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine receptor antagonist with similar potency and nicotinic acetylcholine receptors to a much lesser extent. It has powerful convulsant activity and should not be used in seizure-prone individuals.

Thiomin dosage

Oral

Muscle spasms

Adult: Initially, 16 mg daily.

Intramuscular

Muscle spasms

Adult: Up to 8 mg daily.

Thiomin interactions

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LEXOTAN undergoes hepatic microsomal oxidation via the cytochrome P450 liver enzymes.

Therefore, caution should be taken in patients taking medicines that inhibit the P450 liver enzymes (e.g. azole antifungals, macrolide antibiotics, HIV protease inhibitors, calcium channel blocking agents).

LEXOTAN undergoes oxidative metabolism and, consequently, may interact with disulfiram or cimetidine resulting in increased plasma levels of LEXOTAN. Patients should be observed closely for evidence of enhanced benzodiazepine response during concomitant treatment with either disulfiram or cimetidine; some patients may require a reduction in benzodiazepine dosage.

The benzodiazepines, including LEXOTAN, produce additive CNS depressant effects when coadministered with other medications which themselves produce CNS depression e.g. barbiturates, alcohol, sedatives, antidepressants, hypnotics, anxiolytics, phenothiazines and other antipsychotics,

skeletal muscle relaxants, antihistamines, narcotic analgesics and anaesthetics.

Alcohol should be avoided in patients receiving LEXOTAN.

In the case of narcotic analgesics enhancement of euphoria may also occur, leading to an increase in psychic drug dependence.

The anticholinergic effects of atropine and similar medicines, antihistamines and antidepressants may be potentiated.

Interactions have been reported between some benzodiazepines and anticonvulsants, with changes in the serum concentration of the benzodiazepine or anticonvulsant. It is recommended that patients be observed for altered responses when benzodiazepines and anticonvulsants are prescribed together and that serum level monitoring of the anticonvulsant be performed more frequently.

Interference with Clinical, Laboratory or Other Tests:

Minor EEG changes, usually low voltage fast activity, of no known clinical significance, has been

reported with benzodiazepine administration.

Thiomin side effects

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Photosensitivity reactions,Thiomin Tablets and capsules may cause irritation of the digestive system. Therefore, your doctor Thiomin tablets / capsules during your use of gastric protective drugs may tell you to use. Follow your doctor’s instructions.

If diarrhea occurs In such a situation should reduce your dosage. Thiomin rest, physical therapy and other measures, including pain relief is only one part of the complete treatment program.

Avoid drinking alcohol. Alkol Thiomin alcohol may increase some side effects.

Thiomin contraindications

If you are allergic to any drugs, or if you have any of the following conditions inform your doctor before using Thiomin:

kidney disease;

bleeding problems; The drugs prevent blood clotting [warfarin sodium ( Coumadin )] utilization.

Active ingredient matches for Thiomin:

Thiocolchicoside in India.


Unit description / dosage (Manufacturer)Price, USD
Thiomin 4mg CAP / 10x10$ 10.84
THIOMIN cap 4 mg x 10's (Intra (Intra Life))$ 1.08

List of Thiomin substitutes (brand and generic names):

THIOMEP tab 4 mg x 10's (Pax Healthcare)
Thionaid-P Thiocolchicoside 4 mg, aceclofenac 100 mg, paracetamol 325 mg. TAB / 10 (Winsome)$ 1.39
THIONAID-P tab 10's (Winsome)$ 1.39
THIOPACE 4MG TABLET 1 strip / 10 tablets each (Minova)$ 1.43
THIOPACE 8MG TABLET 1 strip / 10 tablets each (Minova)$ 2.12
THIOPACE cap 4 mg x 10's (Minova)$ 1.51
THIOPACE cap 8 mg x 10's (Minova)$ 2.29
Thiopace 4mg Tablet (Minova)$ 0.14
Thiopace 8mg Tablet (Minova)$ 0.21
THIOQUEST Capsule/ Tablet / 4mg / 10 units (Alchem International Ltd.)$ 1.18
THIOQUEST Capsule/ Tablet / 4mg (Alchem International Ltd.)
THIOQUEST Capsule/ Tablet / 8mg (Alchem International Ltd.)
THIOQUEST Capsule/ Tablet / 8mg / 10 units (Alchem International Ltd.)$ 2.23
THIOQUEST Injection / 4mg / 6x2ml units (Alchem International Ltd.)$ 2.07
Thioquest 4mg SG-CAP / 10 (Alchem International Ltd.)$ 1.18
Thioquest 8mg SG-CAP / 10 (Alchem International Ltd.)$ 2.23
Thioquest 4 mg Tablet (Alchem International Ltd.)$ 0.12
Thioquest 8 mg Capsule (Alchem International Ltd.)$ 0.22
THIOQUEST 4 MG INJECTION 1 vial / 2 ML injection each (Alchem International Ltd.)$ 1.99
THIOQUEST 4 MG TABLET 1 strip / 10 tablets each (Alchem International Ltd.)$ 1.57
THIOQUEST 8 MG TABLET 1 strip / 10 tablets each (Alchem International Ltd.)$ 2.65
THIOQUEST soft-gelatin cap 4 mg x 10's (Alchem International Ltd.)$ 1.45
THIOQUEST soft-gelatin cap 8 mg x 10's (Alchem International Ltd.)$ 2.41
Thioquest 4mg SG-CAP / 10 (Alchem International Ltd.)$ 1.18
Thioquest 8mg SG-CAP / 10 (Alchem International Ltd.)$ 2.23
Thioquest 4mg Capsule (Alchem International Ltd.)$ 0.16
Thioquest 8mg Capsule (Alchem International Ltd.)$ 0.27
Thioquest-DP Thiocolchicoside 4 mg, diclofenac sodium 50 mg, paracetamol 325 mg. CAP / 10 (Alchem)$ 1.27
Thioquest-DP Thiocolchicoside 8 mg, diclofenac sodium 50 mg, paracetamol 325 mg. CAP / 10 (Alchem)$ 2.17
THIOQUEST-DP cap 10's (Alchem)$ 2.65
THIOREST 4MG CAPSULE 1 strip / 10 capsules each (Ajanta Pharma Ltd)$ 1.10
THIOREST 8MG CAPSULE 1 strip / 10 capsules each (Ajanta Pharma Ltd)$ 1.85
Thiorest 8mg Capsule (Ajanta Pharma Ltd)$ 0.19
THIOSAF 8MG CAPSULE 1 strip / 10 capsules each (SAF Fermion Ltd)$ 2.32
4 mg x 100's (Sozin Pharma)
8 mg x 100's (Sozin Pharma)
Thiosoz 4mg CAP / 100 (Sozin Pharma)
Thiosoz 8mg CAP / 100 (Sozin Pharma)
THIOSOZ cap 4 mg x 10's (Sozin Pharma)
THIOSOZ cap 8 mg x 10's (Sozin Pharma)
Thiosoz 4mg CAP / 100 (Sozin Pharma)
Thiosoz 8mg CAP / 100 (Sozin Pharma)
Thiospas 4mg CAP / 10 (Piramal Healthcare)$ 1.13

References

  1. PubChem. "Thiocolchicoside". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Thiocolchicoside". http://www.drugbank.ca/drugs/DB11582 (accessed September 17, 2018).
  3. MeSH. "MeSH Tree: MeSH (Medical Subject Headings) is the NLM controlled vocabulary thesaurus used for indexing articles for PubMed.". http://www.nlm.nih.gov/mesh/meshhome... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Thiomin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Thiomin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

2 consumers reported useful

Was the Thiomin drug useful in terms of decreasing the symptom or the disease?
According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
Users%
Useful1
50.0%
Not useful1
50.0%


1 consumer reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Thiomin drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users%
Expensive1
100.0%


1 consumer reported time for results

To what extent do I have to use Thiomin before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 2 weeks and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Thiomin. To get the time effectiveness of using Thiomin drug by other patients, please click here.
Users%
2 weeks1
100.0%


2 consumers reported age

Users%
> 602
100.0%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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