Toloxatone Uses

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Toloxatone indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Oral

Depression

Adult: 200 mg tid.

Toloxatone description

Toloxatone is an antidepressant launched in 1984 in France for the treatment of depression. It acts as a selective reversible inhibitor of MAO-A (RIMA).

Toloxatone dosage

Oral

Depression

Adult: 200 mg tid.

Toloxatone interactions

Increased risk of serotonin syndrome with SSRI, TCA. Increased BP with sympathomimetics. Increased concentration of triptans.

Potentially Fatal: Increased risk of hypertension and CNS excitation when given with MAOI, wait for 15-20 days after end of MAOI therapy before starting Toloxatone.

Toloxatone side effects

Dysuria, nausea, constipation, vertigo, insomnia.

Potentially Fatal: Fulminant hepatitis.

Toloxatone contraindications

Pregnancy, lactation.

Active ingredient matches for Toloxatone:

Toloxatone


List of Toloxatone substitutes (brand and generic names)

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References

  1. PubChem. "Toloxatone". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Toloxatone". http://www.drugbank.ca/drugs/DB09245 (accessed September 17, 2018).
  3. MeSH. "Monoamine Oxidase Inhibitors". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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