Dosage of Tranexamic Acid in details
Tranexamic Acid Dosage
Generic name: Tranexamic Acid 100mg in 1mL
Dosage form: injection, solution
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Immediately before tooth extraction in patients with hemophilia, administer 10 mg per kg body weight of Tranexamic Acid intravenously together with replacement therapy. Following tooth extraction, intravenous therapy, at a dose of 10 mg per kg body weight three to four times daily, may be used for 2 to 8 days.
Note: For patients with moderate to severe impaired renal function, the following dosages are recommended:
| Serum Creatinine (µmol/L) | Tranexamic AcidIntravenous Dosage |
|---|---|
| 120 to 250 (1.36 to 2.83 mg/dL) | 10 mg/kg twice daily |
| 250 to 500 (2.83 to 5.66 mg/dL) | 10 mg/kg daily |
| >500 (>5.66 mg/dL) | 10 mg/kg every 48 hours or 5 mg/kg every 24 hours |
For intravenous infusion, Tranexamic Acid Injection may be mixed with most solutions for infusion such as electrolyte solutions, carbohydrate solutions, amino acid solutions, and Dextran solutions. Heparin may be added to Tranexamic Acid Injection. Tranexamic Acid Injection should NOT be mixed with blood. The drug is a synthetic amino acid, and should NOT be mixed with solutions containing penicillin.
Single-dose vials and ampules
Discard Tranexamic Acid vial or ampule and any remaining portion in the vial/ampule after single use.
The diluted mixture may be stored for up to 4 hours at room temperature prior to patient administration.
More about Tranexamic Acid (Tranexamic Acid)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Support Group
- En Espanol
- 4 Reviews - Add your own review/rating
- Generic Availability
Consumer resources
- Tranexamic Acid
- Tranexamic Acid tablet
- Tranexamic Acid (Advanced Reading)
- Other brands: Lysteda
Professional resources
- Tranexamic Acid (FDA)
Related treatment guides
- Bleeding Disorder
- Factor IX Deficiency
- Hemophilia A
What other drugs will affect Tranexamic Acid?
Tell your doctor about all other medicines you use, especially:
-
any type of medication to treat a bleeding episode or a blood clot; or
-
factor IX (Bebulin VH, Konyne 80, Profilnine SD, Proplex T, and others).
This list is not complete and other drugs may interact with Tranexamic Acid. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Tranexamic Acid interactions
Contraindications for Co-Administration: Tranexamic Acid should not be co-adminstered with thrombin. Co-administration may cause a thrombosis tendency. It increases the tendency towards thrombosis due to the thrombogenic property of Tranexamic Acid.
Precautions for Co-Administration: Tranexamic Acid should be administered with care when co-administered with the following drugs.
Hemocoagulase: Co-administration at high doses may cause a thrombosis tendency. Due to the antiplasmin action of Tranexamic Acid, fibrin clots formed by hemocoagulase may persist in the blood stream for a relatively long period of time, which may result in a prolonged thrombotic state.
Batroxobin: Co-administration may cause thromboembolism. Tranexamic Acid inhibits the decomposition of desA fibrin polymer produced by batroxobin.
Coagulation Factor Agents (Eptacog-α): Coagulation may be further activated at sites with enhanced local fibrinolysis eg, the oral cavity. Coagulation factors exert hemostatic actions by activating the coagulation system, where as Tranexamic Acid exerts hemostatic actions by inhibiting the fibrinolytic system.
References
- DailyMed. "TRANEXAMIC ACID: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- FDA/SPL Indexing Data. "37YD696II6: The UNique Ingredient Identifier (UNII) is an alphanumeric substance identifier from the joint FDA/USP Substance Registration System (SRS).". https://www.fda.gov/ForIndustry/Data... (accessed September 17, 2018).
- MeSH. "Antifibrinolytic Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Tranexamic Acid are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Tranexamic Acid. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
3 consumers reported frequency of use
How frequently do I need to take Tranexamic Acid?It was reported by ndrugs.com website users that Tranexamic Acid should ideally be taken 3 times in a day as the most common frequency of the Tranexamic Acid. You should you adhere strictly to the instructions and guidelines provided by your doctor on how frequently this Tranexamic Acid should be taken. Get another patient's view on how frequent the capsule should be used by clicking here.
| Users | % | ||
|---|---|---|---|
| 3 times in a day | 2 | 66.7% | |
| Once in a day | 1 | 33.3% | |
9 consumers reported doses
What doses of Tranexamic Acid drug you have used?The drug can be in various doses. Most anti-diabetic, anti-hypertensive drugs, pain killers, or antibiotics are in different low and high doses and prescribed by the doctors depending on the severity and demand of the condition suffered by the patient. In our reports, ndrugs.com website users used these doses of Tranexamic Acid drug in following percentages. Very few drugs come in a fixed dose or a single dose. Common conditions, like fever, have almost the same doses, e.g., [acetaminophen, 500mg] of drug used by the patient, even though it is available in various doses.
| Users | % | ||
|---|---|---|---|
| 201-500mg | 8 | 88.9% | |
| 501mg-1g | 1 | 11.1% | |
Consumer reviews
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Information checked by Dr. Sachin Kumar, MD Pharmacology
