Tremoxyl Pregnancy

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Pregnancy of Tremoxyl in details

Pregnancy is always a special situation where every action or side effect of the drug varies when compared to a situation of a non-pregnant patient. It is not only because the pregnant woman's metabolism differs due to the hormonal and other changes happened to her, but also because every medicine or its metabolite passes to the baby and shows its action there. The only thing is, be cautious, attentive and well supervised when you take any single drug in pregnancy. The interactions can vary in pregnancy, and the dosage may differ as well. Strict supervision of the Physician is mandatory.
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Tremoxyl has not been formally assigned to a pregnancy category by the FDA. There are no controlled data in animal or human pregnancy. Tremoxyl is only recommended for use during pregnancy when need has been clearly established and benefit outweighs risk.

In a large prospective study of 2323 exposures during the first trimester, atropine-related drugs as a whole were possibly associated with minor fetal malformations. However, only 9 of those exposures were to Tremoxyl.

See references

Tremoxyl breastfeeding

When a drug is taken when the patient is breast feeding, a part of the drug is secreted in her breast milk and is passed to the baby. The dosage of the medicine to mother and baby are different, and many drugs actions are side effects when you take them without a disease, and what if you the baby takes them without a disease? What if the drug is contraindicated in newborns, infants or children? So, breastfeeding is a very alarming situation when the mother is on medications. Ask your Physician or Pediatrician about the effect of the drug on the baby and how much is excreted in breast milk and if it harms the baby!

There are no data on the excretion of Tremoxyl into human milk.

See references

References for pregnancy information

  1. "Product Information. Artane (Tremoxyl)." Lederle Laboratories, Wayne, NJ.
  2. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):

References for breastfeeding information

  1. "Product Information. Artane (Tremoxyl)." Lederle Laboratories, Wayne, NJ.


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References

  1. PubMed Health. "Artane: This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).
  2. Human Metabolome Database (HMDB). "Trihexyphenidyl: The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.". http://www.hmdb.ca/metabolites/HMDB0... (accessed September 17, 2018).
  3. LiverTox. "Trihexyphenidyl: LIVERTOX provides up-to-date, accurate, and easily accessed information on the diagnosis, cause, frequency, patterns, and management of liver injury attributable to prescription and nonprescription medications, herbals and dietary supplements. ". https://livertox.nlm.nih.gov//Trihex... (accessed September 17, 2018).

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