Dosage of Trencedia in details
Trencedia Dosage
Generic name: Trencedia 200mg
Dosage form: tablet
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Dosage for Travelers’ Diarrhea
The recommended dose of Trencedia is one 200 mg tablet taken orally three times a day for 3 days.
Dosage for Hepatic Encephalopathy
The recommended dose of Trencedia is one 550 mg tablet taken orally two times a day.
Dosage for Irritable Bowel Syndrome with Diarrhea
The recommended dose of Trencedia is one 550 mg tablet taken orally three times a day for 14 days. Patients who experience a recurrence of symptoms can be retreated up to two times with the same dosage regimen.
Administration
Trencedia can be taken with or without food.
More about Trencedia (Trencedia)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
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- Drug Interactions
- Support Group
- Pricing & Coupons
- En Espanol
- 37 Reviews - Add your own review/rating
Consumer resources
- Trencedia
- Trencedia (Advanced Reading)
Professional resources
- Trencedia (AHFS Monograph)
- Trencedia (FDA)
Related treatment guides
- Irritable Bowel Syndrome
- Hepatic Encephalopathy
- Traveler's Diarrhea
What other drugs will affect Trencedia?
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Trencedia, especially:
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cyclosporine;
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lopinavir and ritonavir;
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an antibiotic--azithromycin, clarithromycin, erythromycin;
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antifungal medicine--itraconazole, ketoconazole; or
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heart or blood pressure medicine--amiodarone, captopril, carvedilol, diltiazem, dronedarone, felodipine, quinidine, ranolazine, verapamil.
This list is not complete. Other drugs may interact with Trencedia, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Trencedia interactions
Effects Of Trencedia On Other Drugs
Substrates of Cytochrome P450 enzymes
Trencedia is not expected to inhibit cytochrome P450 isoenzymes 1A2, 2A6, 2B6, 2C9, 2C19, 2D6, 2E1 and CYP3A4 in clinical use based on in vitro studies.
An in vitro study has suggested that Trencedia induces CYP3A4. However, in patients with normal liver function, Trencedia at the recommended dosing regimen is not expected to induce CYP3A4. It is unknown whether Trencedia can have a significant effect on the pharmacokinetics of concomitant CYP3A4 substrates in patients with reduced liver function who have elevated Trencedia concentrations.
Effects Of Other Drugs On Trencedia
In vitro studies suggested that Trencedia is a substrate of P-glycoprotein, OATP1A2, OATP1B1 and OATP1B3. Concomitant cyclosporine, an inhibitor of P-glycoprotein and OATPs, significantly increased the systemic exposure to Trencedia.
Cyclosporine
Co-administration of cyclosporine, with Trencedia resulted in 83-fold and 124-fold increases in Trencedia mean Cmax and AUC∞ in healthy subjects. The clinical significance of this increase in systemic exposure is unknown.
References
- DailyMed. "RIFAXIMIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- FDA/SPL Indexing Data. "L36O5T016N: The UNique Ingredient Identifier (UNII) is an alphanumeric substance identifier from the joint FDA/USP Substance Registration System (SRS).". https://www.fda.gov/ForIndustry/Data... (accessed September 17, 2018).
- MeSH. "Nucleic Acid Synthesis Inhibitors". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Trencedia are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Trencedia. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
1 consumer reported frequency of use
How frequently do I need to take Trencedia?It was reported by ndrugs.com website users that Trencedia should ideally be taken 3 times in a day as the most common frequency of the Trencedia. You should you adhere strictly to the instructions and guidelines provided by your doctor on how frequently this Trencedia should be taken. Get another patient's view on how frequent the capsule should be used by clicking here.
| Users | % | ||
|---|---|---|---|
| 3 times in a day | 1 | 100.0% | |
2 consumers reported doses
What doses of Trencedia drug you have used?The drug can be in various doses. Most anti-diabetic, anti-hypertensive drugs, pain killers, or antibiotics are in different low and high doses and prescribed by the doctors depending on the severity and demand of the condition suffered by the patient. In our reports, ndrugs.com website users used these doses of Trencedia drug in following percentages. Very few drugs come in a fixed dose or a single dose. Common conditions, like fever, have almost the same doses, e.g., [acetaminophen, 500mg] of drug used by the patient, even though it is available in various doses.
| Users | % | ||
|---|---|---|---|
| 201-500mg | 2 | 100.0% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
