Pregnancy of Treonam in details
Treonam crosses the placenta and reaches the fetal circulation following IV administration; however, peak plasma concentrations following inhalation of Treonam are significantly less than those observed following Treonam IV.
Due to its poor systemic absorption, use of Treonam inhalation is likely acceptable for the management of cystic fibrosis in pregnant patients with Pseudomonas aeruginosa (Kroon 2018; Middleton 2019). When required, use may continue during pregnancy (Middleton 2019).
Treonam breastfeeding
Treonam is excreted into human milk in small amounts that are less than 1% of maternal serum concentrations. Systemic effects in the infant are considered unlikely. Treonam is considered compatible with breast-feeding by the American Academy of Pediatrics.
See references
References for pregnancy information
- "Product Information. Azactam (Treonam)." Bristol-Myers Squibb, Princeton, NJ.
- "Product Information. Cayston (Treonam)." Gilead Sciences, Foster City, CA.
References for breastfeeding information
- Committee on Drugs, 1992 to 1993 "The transfer of drugs and other chemicals into human milk." Pediatrics 93 (1994): 137-50
- Fleiss PM, Richwald GA, Gordon J, et al "Treonam in human serum and breast milk." Br J Clin Pharmacol 19 (1985): 509-11
- Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):
- "Product Information. Cayston (Treonam)." Gilead Sciences, Foster City, CA.
- "Product Information. Azactam (Treonam)." Bristol-Myers Squibb, Princeton, NJ.
References
- DailyMed. "MEROPENEM: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "AZTREONAM: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubMed Health. "Meropenem (By injection) (Meropenem Novaplus): This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).
Reviews
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology