Trinadep Uses

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What is Trinadep?

Trinadep is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Trinadep affects chemicals in the brain that may become unbalanced and cause anxiety.

Trinadep is used to treat anxiety disorders or alcohol withdrawal.

Trinadep may also be used for other purposes not listed in this medication guide.

Trinadep indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Trinadep Hydrochloride Capsule is indicated for the management of anxiety disorders or for the short term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic.

The effectiveness of Trinadep Hydrochloride Capsule in long-term use, that is, more than 4 months, has not been assessed by systematic clinical studies. The physician should periodically reassess the usefulness of the drug for the individual patient.

How should I use Trinadep?

Use Trinadep injection as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Trinadep injection.

Uses of Trinadep in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Trinadep is used to treat anxiety and acute alcohol withdrawal. It is also used to relieve fear and anxiety before surgery. This medication belongs to a class of drugs called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA).

How to use Trinadep

Take this medication by mouth as directed by your doctor. The dosage is based on your age, medical condition, and response to treatment.

Use this medication exactly as prescribed. Do not increase your dose, take it more frequently or use it for a longer period of time than prescribed because this drug can be habit-forming. Also, if used for an extended period of time, do not suddenly stop using this drug without your doctor's approval. Some conditions may become worse when the drug is abruptly stopped. Your dose may need to be gradually decreased to avoid side effects such as seizures.

When used for an extended period, this medication may not work as well and may require different dosing. Talk with your doctor if this medication stops working well.

Trinadep description

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A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Trinadep has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of anxiety disorders, and also for the short-term management of insomnia but has largely been superseded by the benzodiazepines. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603) Trinadep is a controlled substance in the U.S.

Trinadep dosage

Trinadep Dosage

Applies to the following strength(s): 5 mg; 10 mg; 25 mg; 100 mg

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Geriatric Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Anxiety

Mild to moderate anxiety: 5 or 10 mg orally, 3 or 4 times per day

Severe anxiety: 20 or 25 mg orally, 3 or 4 times per day

Use: Relief of mild, moderate, and severe anxiety disorders

Usual Adult Dose for Light Sedation

On days preceding surgery, 5 to 10 mg orally, 3 or 4 times per day

Use: Relief of preoperative apprehension and anxiety

Usual Adult Dose for Alcohol Withdrawal

50 to 100 mg orally, followed by repeated doses as needed until agitation is controlled

Maximum dose: 300 mg orally per day

Use: Relief of withdrawal symptoms of acute alcoholism

Usual Geriatric Dose for Anxiety

Elderly or debilitated patients:

5 mg orally, 2 to 4 times per day

Use: Relief of mild, moderate, and severe anxiety disorders

Usual Pediatric Dose for Anxiety

6 years or older:

5 mg orally, 2 to 4 times per day; this may be increased to 10 mg orally, 2 to 3 times per day

Use: Relief of mild, moderate, and severe anxiety disorders

Renal Dose Adjustments

Renal impairment: Use with caution

Liver Dose Adjustments

Hepatic impairment: Use with caution

Precautions

Safety and efficacy have not been established in patients younger than 6 years.

Consult WARNINGS section for additional precautions.

US Controlled Substance: Schedule IV

Dialysis

Data not available

Other Comments

Storage requirements:

-Protect from light

Monitoring:

-Psychiatric: Patients with a history of alcohol or drug abuse, or patients with a marked personality disorder should be monitored frequently.

Patient advice:

-Patients should be cautioned against performing activities requiring complete mental alertness, such as operating machinery or driving a motor vehicle.

More about Trinadep

Consumer resources

Professional resources

Related treatment guides

Trinadep interactions

See also:
What other drugs will affect Trinadep?

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When this drug applied simultaneously with:

- antipsychotic drugs (neuroleptics), antidepressants, sedatives, hypnotics, anesthetics, analgesics, ethanol enhanced the inhibitory effect on central nervous system, especially when administered parenterally.

- concomitant use of antacids can delay but not reduce the absorption of Trinadep.

- hormonal contraceptives increases the effectiveness of Trinadep.

- with muscle relaxants may enhance the action of muscle relaxants, with levodopa - may suppress antiparkinsonian action.

- theophylline at low doses perverts sedative effect of Trinadep.

- phenobarbital and phenytoin may accelerate the metabolism of Trinadep. In rare cases this medication inhibits the metabolism and enhances the action of phenytoin.

- may increase the toxicity of cyclophosphamide.

- cimetidine, omeprazole, disulfiram may increase the intensity and duration of action of this medicine.

Trinadep side effects

See also:
What are the possible side effects of Trinadep?

Applies to Trinadep: oral capsule, oral tablet

As well as its needed effects, Trinadep (the active ingredient contained in Trinadep) may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking Trinadep, check with your doctor immediately:

Rare

Incidence not known:

If any of the following symptoms of overdose occur while taking Trinadep, get emergency help immediately:

Symptoms of overdose:

Minor Side Effects

Some Trinadep side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Incidence not known:

Trinadep contraindications

See also:
What is the most important information I should know about Trinadep?

this medicine is contraindicated in the presence of glaucoma (since the anticholinergic component may produce some degree of mydriasis) and in patients with prostatic hypertrophy and benign bladder neck obstruction. It is contraindicated in patients with known hypersensitivity to Trinadep hydrochloride and/or clidinium bromide.

Active ingredient matches for Trinadep:

Chlordiazepoxide


Unit description / dosage (Manufacturer)Price, USD
Trinadep 10+1 Tablet$ 0.03

List of Trinadep substitutes (brand and generic names):

Tridium 10mg Tablet (S.P.Pharmaceuticals)$ 0.03
Trinadep CB 10+2.5 Tablet (Meditrina Biotech Pvt Ltd.)$ 0.04
Tripoxide 1+10 Tablet (Sayora Pharma (P) Ltd.)$ 0.02
Trixia Chlordiazepoxide 10 mg, Trifluoperazine 1 mg. TAB / 10 (Winsome Laboratories Ltd.)$ 0.24
10's (Winsome Laboratories Ltd.)$ 0.24
Trixia 10+1 Tablet (Winsome Laboratories Ltd.)$ 0.03
TRIXIA 1MG/10MG TABLET 1 strip / 10 tablets each (Winsome Laboratories Ltd.)$ 0.24
TRIXIA tab 10's (Winsome Laboratories Ltd.)$ 0.24
Trixia 10 mg/1 mg Tablet (Winsome Laboratories Ltd.)$ 0.02
Trixide H 12.5+5 Tablet (Talent Healthcare)$ 0.02
TRIXIDE H 25MG/10MG TABLET 1 strip / 10 tablets each (Talent Healthcare)$ 0.29
Trizen 10+1 Tablet (Zaneka Pharmaceuticals (P) Ltd.)$ 0.03
TRIZEN 1MG/10MG TABLET 1 strip / 10 tablets each (Zaneka Pharmaceuticals (P) Ltd.)$ 0.31
Trizen 10 mg/1 mg Tablet (Zaneka Pharmaceuticals (P) Ltd.)$ 0.03
Trizep Trifluoperazine 1 mg, Chlordiazepoxide 10 mg. FC-TAB / 10 (Siomond Pharmaceuticals Pvt Ltd)$ 0.21
10's (Siomond Pharmaceuticals Pvt Ltd)$ 0.21
Trizep 1+10 Tablet (Siomond Pharmaceuticals Pvt Ltd)$ 0.02
TRIZEP 1MG/10MG TABLET 1 strip / 10 tablets each (Siomond Pharmaceuticals Pvt Ltd)$ 0.20
TRIZEP film-coated tab 10's (Siomond Pharmaceuticals Pvt Ltd)$ 0.21
Trizep 1 mg/10 mg Tablet (Siomond Pharmaceuticals Pvt Ltd)$ 0.02
Trociz 10+1 Tablet (Excare Laboratories)$ 0.02
Trofaz CZ 10+1 Tablet (Olcare Laboratories)$ 0.02
Tryline Forte 10+25 Tablet (S.P.Pharmaceuticals)$ 0.02
Tryline Plus 5+12.5 Tablet (S.P.Pharmaceuticals)$ 0.02
Typlin C 5+12.5 Tablet (Sterkem Pharma Pvt Ltd)$ 0.02
Typlin C 12.5 mg/5 mg Tablet (Sterkem Pharma Pvt Ltd)$ 0.04
Typlin C Tablet (Sterkem Pharma Pvt Ltd)$ 0.04
Ulcon P 5+2.5 Tablet (Unimarck Healthcare Ltd)$ 0.03
ULCON P 2.5MG/5MG TABLET 1 strip / 10 tablets each (Unimarck Healthcare Ltd)$ 0.46
Ulcon P 5 mg/2.5 mg Tablet (Unimarck Healthcare Ltd)$ 0.05
Ulrex P 5+2.5 Tablet (Modgal Pharmaceuticals (P) Ltd.)$ 0.03
Ultra Dep Imipramine hydrochloride 25mg, Chlordiazepoxide 10 mg. TAB / 200 (Ultramark Healthcare Pvt Ltd.)$ 4.76
200's (Ultramark Healthcare Pvt Ltd.)$ 4.76
Ultra Dep 25+10 Tablet (Ultramark Healthcare Pvt Ltd.)$ 0.02
ULTRA DEP coated tab 10's (Ultramark Healthcare Pvt Ltd.)$ 0.24
Ultradep 25+10 Tablet (Ultramark Healthcare Pvt Ltd.)$ 0.04
VIZEP 10MG TABLET 1 strip / 10 tablets each (Kivi Labs Ltd)$ 0.35
VIZEP 25MG TABLET 1 strip / 10 tablets each (Kivi Labs Ltd)$ 0.50
Vizep 25mg Tablet (Kivi Labs Ltd)$ 0.05
Weldip Chlordiazepoxide 10 mg, Trifluoperazine 1 mg. TAB / 10 (Biochemix Health Care Division)$ 0.29
10's (Biochemix Health Care Division)$ 0.29

References

  1. DailyMed. "AMITRIPTYLINE HYDROCHLORIDE; CHLORDIAZEPOXIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "chlordiazepoxide". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "chlordiazepoxide". http://www.drugbank.ca/drugs/DB00475 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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