What happens if I overdose Vicks Sinex Nasal Spray?
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local, or emergency room immediately.
Proper storage of Vicks Sinex Nasal Spray:
Store Vicks Sinex Nasal Spray at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Vicks Sinex Nasal Spray out of the reach of children and away from pets.
Overdose of Vicks Sinex Nasal Spray in details
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: drowsiness, slow heartbeat, dizziness, fainting.
Notes
Do not share this medication with others. Use of this container by more than one person may spread infection.
There are various nasal decongestants available, many without a prescription. Talk with your doctor or pharmacist about which product is best for you.
Missed Dose
Not applicable.
Storage
Refer to storage information printed on the package. Protect from heat and light. Keep all medicines away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
What should I avoid while taking Vicks Sinex Nasal Spray?
Use caution when driving, operating machinery, or performing other hazardous activities. Phenylephrine ophthalmic may cause blurred vision. If you experience blurred vision, avoid these activities.
Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye.
If you wear contact lenses, remove them before applying phenylephrine ophthalmic. Ask your doctor if contact lenses can be reinserted after application of the medication. Phenylephrine ophthalmic may contain a preservative (benzalkonium chloride), which may cause discoloration of contact lenses.
Do not use phenylephrine ophthalmic more often or continuously for longer than 48 to 72 hours without consulting a doctor. Chronic use of this medication may damage the blood vessels (veins and arteries) in the eyes. Consult a doctor if your symptoms do not improve or appear to worsen.
Vicks Sinex Nasal Spray warnings
There have been rare reports associating the use of Vicks Sinex Nasal Spray (phenylephrine hydrochloride ophthalmic solution) 10 percent ophthalmic solutions with the development of serious cardiovascular reactions, including ventricular arrhythmias and myocardial infarctions. These episodes, some ending fatally, have usually occurred in elderly patients with preexisting cardiovascular diseases.
What should I discuss with my healthcare provider before taking Vicks Sinex Nasal Spray?
Some medical conditions may interact with Vicks Sinex Nasal Spray. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have heart disease, diabetes, prostate problems, high blood pressure, or an overactive thyroid
Some MEDICINES MAY INTERACT with Vicks Sinex Nasal Spray. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Rauwolfia derivatives (eg, reserpine) or tricyclic antidepressants (eg, amitriptyline) because the effectiveness of Vicks Sinex Nasal Spray may be decreased
- Cocaine, furazolidone, methyldopa, MAO inhibitors (eg, phenelzine), oxytocic medicines (eg, oxytocin), rauwolfia derivatives (eg, reserpine), or tricyclic antidepressants (eg, amitriptyline) because the actions and side effects of Vicks Sinex Nasal Spray may be increased
- Bromocriptine, COMT inhibitors (eg, entacapone), cocaine, or droxidopa because the actions and side effects of these medicines may be increased
- Guanethidine because its effectiveness may be decreased by Vicks Sinex Nasal Spray
This may not be a complete list of all interactions that may occur. Ask your health care provider if Vicks Sinex Nasal Spray may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Vicks Sinex Nasal Spray precautions
Exceeding recommended dosages or applying Vicks Sinex Nasal Spray (phenylephrine hydrochloride ophthalmic solution) hydrochloride ophthalmic solutions to the instrumented, traumatized, diseased or postsurgical eye or adnexa, or to patients with suppressed lacrimation, as during anesthesia, may result in the absorption of sufficient quantities of phenylephrine to produce a systemic vasopressor response.
A significant elevation in blood pressure is rare but has been reported following conjunctival instillation of recommended doses of Vicks Sinex Nasal Spray (phenylephrine hydrochloride ophthalmic solution) 10 percent ophthalmic solutions. Caution, therefore, should be exercised in administering the 10 percent solutions to children of low body weight, the elderly, and patients with insulin-dependent diabetes, hypertension, hyperthyroidism, generalized arteriosclerosis, or cardiovascular disease. The posttreatment blood pressure of these patients, and any patients who develop symptoms, should be carefully monitored.
Ordinarily, any mydriatic, including Vicks Sinex Nasal Spray (phenylephrine hydrochloride ophthalmic solution) hydrochloride, is contraindicated in patients with glaucoma, since it may occasionally raise intraocular pressure. However, when temporary dilatation of the pupil may free adhesions or when vasoconstriction of intrinsic vessels may lower intraocular tension, these advantages may temporarily outweigh the danger from coincident dilatation of the pupil.
Rebound miosis has been reported in older persons one day after receiving Vicks Sinex Nasal Spray (phenylephrine hydrochloride ophthalmic solution) hydrochloride ophthalmic solutions, and reinstillation of the drug produced a reduction in mydriasis. This may be of clinical importance in dilating the pupils of older subjects prior to retinal detachment or cataract surgery.
Due to a strong action of the drug on the dilator muscle, older individuals may also develop transient pigment floaters in the aqueous humor 30 to 45 minutes following the administration of Vicks Sinex Nasal Spray (phenylephrine hydrochloride ophthalmic solution) hydrochloride ophthalmic solutions. The appearance may be similar to anterior uveitis or to a microscopic hyphema.
To prevent pain, a drop of suitable topical anesthetic may be applied before using the 10 percent ophthalmic solution.
Carcinogenesis, Mutagenesis, Impairment of Fertility: No long-term animal studies have been done to evaluate the potential of Vicks Sinex Nasal Spray (phenylephrine hydrochloride ophthalmic solution) in these areas.
Pregnancy Category C: Animal reproduction studies have not been conducted with Vicks Sinex Nasal Spray (phenylephrine hydrochloride ophthalmic solution). It is also not known whether Vicks Sinex Nasal Spray (phenylephrine hydrochloride ophthalmic solution) can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Vicks Sinex Nasal Spray (phenylephrine hydrochloride ophthalmic solution) should be given to a pregnant woman only if clearly needed.
Nursing Mothers: It is not known whether this drug is excreted in milk; many are. Caution should be exercised when Vicks Sinex Nasal Spray (phenylephrine hydrochloride ophthalmic solution) hydrochloride ophthalmic solution is administered to a nursing woman.
Pediatric Use: Vicks Sinex Nasal Spray (phenylephrine hydrochloride ophthalmic solution) hydrochloride 10 percent ophthalmic solutions are contraindicated in infants. For use in older children see DOSAGE AND ADMINISTRATION.
Exceeding recommended dosages or applying Vicks Sinex Nasal Spray (phenylephrine hydrochloride ophthalmic solution) hydrochloride ophthalmic solutions to the instrumented, traumatized, diseased or postsurgical eye or adnexa, or to patients with suppressed lacrimation, as during anesthesia, may result in the absorption of sufficient quantities of phenylephrine to produce a systemic vasopressor response.
The hypertensive effects of phenylephrine may be treated with an alpha-adrenergic blocking agent such as phentolamine mesylate, 5 mg to 10 mg intravenously, repeated as necessary.
The oral LD50 of phenylephrine in the rat: 350 mg/kg, in the mouse: 120 mg/kg.
What happens if I miss a dose of Vicks Sinex Nasal Spray?
Since Vicks Sinex Nasal Spray is usually used only when needed, you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
References
- DrugBank. "phenylephrine". http://www.drugbank.ca/drugs/DB00388 (accessed September 17, 2018).
- MeSH. "Cardiotonic Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
- EPA Chemicals under the TSCA. "Benzenemethanol, 3-hydroxy-.alpha.-[(methylamino)methyl]- , hydrochloride (1:1), (.alpha.R)-: The Chemical Data Reporting under the Toxic Substances Control Act (TSCA) contains chemical physical description and chemical use categories.". http://www.epa.gov/chemical-data-rep... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology
