What is Viplena?
Viplena blocks some of the fat that you eat, keeping it from being absorbed by your body.
Viplena is used together with a reduced-calorie diet and weight maintenance to treat obesity in people with certain risk factors (such as diabetes, high blood pressure, and high cholesterol or triglycerides).
Viplena may also be used for purposes not listed in this medication guide.
It is dangerous to purchase Viplena on the Internet or from vendors outside of the United States. Medications distributed from Internet sales may contain dangerous ingredients, or may not be distributed by a licensed pharmacy. Samples of "alli" purchased on the Internet have been found to contain sibutramine (Meridia), a prescription weight loss medication that can have dangerous side effects in certain people. For more information, contact the U.S. Food and Drug Administration (FDA) or visit www.fda.gov/buyonlineguide.
Viplena indications
Viplena is indicated for obesity management including weight loss and weight maintenance when used in conjunction with a reduced-calorie diet. Viplena is also indicated to reduce the risk for weight regain after prior weight loss. Viplena is indicated for obese patients with an initial body mass index (BMI) ≥30 kg/m2 or ≥27 kg/m2 in the presence of other risk factors (eg, hypertension, diabetes, dyslipidemia).
Table 1 illustrates body mass index (BMI) according to a variety of weights and heights. The BMI is calculated by dividing weight in kilograms by height in meters squared. For example, a person who weighs 180 lbs and is 5'5" would have a BMI of 30.
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How should I use Viplena?
Use Viplena as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Viplena. Talk to your pharmacist if you have questions about this information.
- Take Viplena by mouth with or up to 1 hour after each main meal that contains fat (up to 3 per day).
- If a meal is missed or contains no fat, do not take a dose of Viplena.
- You should take a multivitamin supplement containing vitamins A, D, E, and K to ensure good nutrition. The supplement should be taken at least 2 hours before or after you take Viplena, such as at bedtime.
- If you also take a thyroid hormone (eg, levothyroxine), do not take it within 4 hours before or after taking Viplena. Check with your doctor if you have questions.
- If you also take cyclosporine, do not take it within 3 hours before or after taking Viplena. Check with your doctor if you have questions.
- If you miss a dose of Viplena, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Viplena.
Uses of Viplena in details
Use: Labeled Indications
Obesity management:
OTC: Weight loss in overweight adults when used along with a reduced-calorie and low-fat diet.
Rx: Obesity management, including weight loss and weight maintenance, when used in conjunction with a reduced-calorie diet; to reduce the risk for weight regain after prior weight loss.
Limitations of use: Viplena is indicated for obese patients with an initial body mass index of ≥30 kg/m in the presence of other risk factors (eg, hypertension, diabetes, dyslipidemia).
Viplena description
Viplena is a drug designed to treat obesity. Its primary function is preventing the absorption of fats from the human diet, thereby reducing caloric intake. Viplena works by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine. Without this enzyme, triglycerides from the diet are prevented from being hydrolyzed into absorbable free fatty acids and are excreted undigested.
Viplena dosage
Viplena Dosage
Generic name: Viplena 120mg
Dosage form: capsule
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Recommended Dosing
The recommended dose of Viplena is one 120-mg capsule three times a day with each main meal containing fat (during or up to 1 hour after the meal).
The patient should be on a nutritionally balanced, reduced-calorie diet that contains approximately 30% of calories from fat. The daily intake of fat, carbohydrate, and protein should be distributed over three main meals. If a meal is occasionally missed or contains no fat, the dose of Viplena can be omitted.
Because Viplena has been shown to reduce the absorption of some fat-soluble vitamins and beta-carotene, patients should be counseled to take a multivitamin containing fat-soluble vitamins to ensure adequate nutrition. The vitamin supplement should be taken at least 2 hours before or after the administration of Viplena, such as at bedtime.
For patients receiving both Viplena and cyclosporine therapy, administer cyclosporine 3 hours after Viplena.
For patients receiving both Viplena and levothyroxine therapy, administer levothyroxine and Viplena at least 4 hours apart. Patients treated concomitantly with Viplena and levothyroxine should be monitored for changes in thyroid function.
Doses above 120 mg three times a day have not been shown to provide additional benefit.
Based on fecal fat measurements, the effect of Viplena is seen as soon as 24 to 48 hours after dosing. Upon discontinuation of therapy, fecal fat content usually returns to pretreatment levels within 48 to 72 hours.
More about Viplena (Viplena)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Espanol
- 74 Reviews - Add your own review/rating
Consumer resources
- Viplena
- Viplena (Advanced Reading)
- Other brands: Alli
Professional resources
- Viplena (AHFS Monograph)
- Viplena (FDA)
Related treatment guides
- Obesity
Viplena interactions
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What other drugs will affect Viplena?
Amiodarone: Viplena may decrease the serum concentration of Amiodarone. Monitor therapy
Anticonvulsants: Viplena may decrease the serum concentration of Anticonvulsants. Exceptions: Fosphenytoin; PENTobarbital; Thiopental. Monitor therapy
Antiretroviral Agents: Viplena may decrease the serum concentration of Antiretroviral Agents. Monitor therapy
CycloSPORINE (Systemic): Viplena may decrease the serum concentration of CycloSPORINE (Systemic). Management: Administer Viplena at least 3 hours before or after oral cyclosporine. Monitor for decreased serum concentrations of oral cyclosporine, even with the recommended dose separation. Consider therapy modification
Levothyroxine: Viplena may decrease the serum concentration of Levothyroxine. Management: Separate administration of oral levothyroxine and Viplena by a least 4 hours. Monitor patients closely for signs and symptoms of hypothyroidism. Consider therapy modification
Multivitamins/Fluoride (with ADE): Viplena may decrease the serum concentration of Multivitamins/Fluoride (with ADE). Specifically, Viplena may impair absorption of fat-solube vitamins. Management: Administer oral fat soluble vitamins (such as vitamins A, D, E, and/or K that are contained in many multivitamin products) at least 2 hours before or after the administration of Viplena. Consider therapy modification
Multivitamins/Minerals (with ADEK, Folate, Iron): Viplena may decrease the serum concentration of Multivitamins/Minerals (with ADEK, Folate, Iron). Specifically, Viplena may impair the absorption of fat-soluble vitamins. Management: Administer oral fat soluble vitamins (such as vitamins A, D, E, and/or K that are contained in many multivitamin products) at least 2 hours before or after the administration of Viplena. Consider therapy modification
Multivitamins/Minerals (with AE, No Iron): Viplena may decrease the serum concentration of Multivitamins/Minerals (with AE, No Iron). Specifically, Viplena may impair absorption of fat-solube vitamins. Management: Administer oral fat soluble vitamins (such as vitamins A, D, E, and/or K that are contained in many multivitamin products) at least 2 hours before or after the administration of Viplena. Consider therapy modification
Paricalcitol: Viplena may decrease the serum concentration of Paricalcitol. Management: Monitor clinical response to paricalcitol closely when used with Viplena. When this combination must be used, consider administering paricalcitol at least 1 hour before or 4 to 6 hours after the administration of Viplena Consider therapy modification
Propafenone: Viplena may decrease the serum concentration of Propafenone. Monitor therapy
Sincalide: Drugs that Affect Gallbladder Function may diminish the therapeutic effect of Sincalide. Management: Consider discontinuing drugs that may affect gallbladder motility prior to the use of sincalide to stimulate gallbladder contraction. Consider therapy modification
Vitamin D Analogs: Viplena may decrease the serum concentration of Vitamin D Analogs. More specifically, Viplena may impair absorption of Vitamin D Analogs. Management: Monitor clinical response (including serum calcium) to oral vitamin D analogs closely if used with Viplena. If this combination must be used, consider giving the vitamin D analog at least 2 hrs before or after Viplena. Exceptions: Calcipotriene; Calcitriol (Topical); Tacalcitol. Consider therapy modification
Vitamin K Antagonists (eg, warfarin): Viplena may enhance the anticoagulant effect of Vitamin K Antagonists. Monitor therapy
Vitamins (Fat Soluble): Viplena may decrease the serum concentration of Vitamins (Fat Soluble). Management: Administer oral fat soluble vitamins at least 2 hours before or after the administration of Viplena. Similar precautions do not apply to parenterally administered fat soluble vitamins. Exceptions: Calcipotriene. Consider therapy modification
Viplena side effects
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What are the possible side effects of Viplena?
The majority of unwanted effects related to the use of Viplena result from its local action in your digestive system. These commonly include: urgent or increased need to open the bowels, flatulence (wind) with discharge, oily discharge and oily or fatty stools. The possibility of this happening may increase if Viplena is taken with a diet high in fat. In addition your daily intake of fat should be distributed evenly over three main meals because if Viplena is taken with a meal very high in fat, the possibility of gastrointestinal effects may increase. The more fat you eat, the more fat in your stools, and the more you will experience these dietary events. The frequency and onset of these dietary events varies from one person to another and depends on how much fat is consumed. They usually occur more frequently in the beginning of your program, and will gradually disappear as you develop new eating habits. Most importantly, you can control these dietary events when you control your fat intake. It is not Viplena alone, but the excess fat that you eat while taking Viplena that causes these events. Try not to exceed your daily fat allowance as calculated by your doctor or dietician.
Rare cases of allergic reactions have occurred with Viplena. The main symptoms are itching, rash, wheals (slightly elevated, itchy skin patches that are paler or redder than surrounding skin), difficulty in breathing, nausea, vomiting and feeling unwell. Very rarely increases in liver enzyme levels have been reported. If you are concerned about these or notice any side effects not mentioned in this leaflet, please inform your doctor or pharmacist.
Viplena contraindications
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What is the most important information I should know about Viplena?
Do not take Viplena if you are pregnant. Weight loss is not recommended during pregnancy, even if you are overweight or obese.
You should not take this medication if you are allergic to Viplena, if you are pregnant, or if you have gallbladder problems or chronic malabsorption syndrome (an inability to absorb food and nutrients properly).
Before taking Viplena, tell your doctor if you have an underactive thyroid, a history of gallstones or pancreatitis, type 1 or type 2 diabetes, an eating disorder, liver or kidney disease, or if you take other weight-loss medications (prescription or over-the-counter).
Do not give over-the-counter Viplena (alli) to a child younger than 18 years old. Prescription Viplena should not be used by anyone age 12 to 18 without the advice of a doctor.
Viplena should be used only by the person for whom it was prescribed. Never share Viplena with another person, especially someone who has a history of eating disorder. Keep the medication in a place where others cannot get to it.
Viplena is only part of a complete program of treatment that also includes diet, exercise, and weight control. Your daily intake of fat, protein, and carbohydrates should be evenly divided over all of your daily meals. Follow your diet, medication, and exercise routines very closely.
Avoid a diet that is high in fat. High-fat meals taken in combination with Viplena can increase your risk of unpleasant side effects on your stomach or intestines.
Active ingredient matches for Viplena:
Orlistat in Chile, Ecuador, Peru.
| Unit description / dosage (Manufacturer) | Price, USD |
| Capsule; Oral; Orlistat 120 mg | |
List of Viplena substitutes (brand and generic names): | |
| Verte (Peru) | |
| Viplena 120 (Vietnam) | |
| Viplena 120 120 mg x 2 Blister x 10 Tablet | |
| Vyfat (India) | |
| Vyfat 120mg CAP / 10 (Intas Pharmaceuticals Ltd.) | $ 4.64 |
| 120 mg x 10's (Intas Pharmaceuticals Ltd.) | $ 4.22 |
| Vyfat 120 mg Capsule (Intas Pharmaceuticals Ltd.) | $ 0.46 |
| Vyfat 60 mg Capsule (Intas Pharmaceuticals Ltd.) | $ 0.24 |
| VYFAT 120 MG CAPSULE 1 strip / 10 capsules each (Intas Pharmaceuticals Ltd.) | $ 5.78 |
| VYFAT cap 120 mg x 10's (Intas Pharmaceuticals Ltd.) | $ 4.64 |
| Vyfat 120mg Capsule (Intas Pharmaceuticals Ltd.) | $ 0.63 |
| Wintal (Peru) | |
| Wintal 30 mg Injection (Indus Pharma Pvt. Ltd.) | $ 0.08 |
| WONLISTAT (India) | |
| WONLISTAT tab 60 mg x 10's (Wonder (Xtra)) | |
| WONLISTAT tab 120 mg x 10's (Wonder (Xtra)) | |
| X Slim-Humanity (Georgia) | |
| Xenical (Argentina, Armenia, Aruba, Australia, Austria, Bangladesh, Belarus, Belgium, Bolivia, Bosnia & Herzegowina, Botswana, Brazil, Brunei Darussalam, Cambodia, Canada, Chile, China, Colombia, Croatia (Hrvatska), Cuba, Cyprus, Czech Republic, Denmark, Ecuador, Estonia, Finland, France, Georgia, Germany, Ghana, Greece, Hong Kong, Hungary, Iceland, Indonesia, Ireland, Israel, Italy, Jamaica, Jordan, Kazakhstan, Kenya, Kuwait, Laos, Lebanon, Lithuania, Luxembourg, Macedonia, Malawi, Malaysia, Mexico, Morocco, Namibia, Netherlands, New Zealand, Nigeria, Norway, Oman, Pakistan, Paraguay, Peru, Philippines, Poland, Portugal, Qatar, Romania, Russian Federation, Saudi Arabia, Serbia, Singapore, Slovakia, Slovenia, South Africa, South Korea, Spain, Sri Lanka, Sudan, Sweden, Switzerland, Taiwan, Tanzania, Thailand, Trinidad & Tobago, Turkey, Turkmenistan, Uganda, Ukraine, United Arab Emirates, United Kingdom, United States, Uruguay, Uzbekistan, Venezuela, Vietnam, Zambia, Zimbabwe) | |
| Capsule; Oral; Orlistat 120 mg (USV-Corvette (US Vitamins Ltd)) | |
| Generic Xenical 120mg - 42 Capsule (USV-Corvette (US Vitamins Ltd)) | $ 114.95 |
| Generic Xenical 120mg - 84 Capsule (USV-Corvette (US Vitamins Ltd)) | $ 199.95 |
| Xenical 120 mg - 21 Tablets (USV-Corvette (US Vitamins Ltd)) | $ 57.20 |
| Xenical 120 mg x 4 x 21's (USV-Corvette (US Vitamins Ltd)) | |
| Xenical 120 mg x 21's (USV-Corvette (US Vitamins Ltd)) | $ 22.81 |
| Xenical 120 mg x 84's (USV-Corvette (US Vitamins Ltd)) | |
| Xenical 120 mg x 21 Tablet (USV-Corvette (US Vitamins Ltd)) | |
| Xenical 120 mg x 42's (USV-Corvette (US Vitamins Ltd)) | |
| Xenical 120 mg x 4 Blister x 21 Tablet (USV-Corvette (US Vitamins Ltd)) | |
| Xenical 120 mg Capsule (USV-Corvette (US Vitamins Ltd)) | $ 0.63 |
| XENICAL 120 MG CAPSULE 1 strip / 21 capsules each (USV-Corvette (US Vitamins Ltd)) | $ 13.35 |
| XENICAL cap 120 mg x 10's (USV-Corvette (US Vitamins Ltd)) | $ 5.78 |
| Xenical cap 120 mg 21's (USV-Corvette (US Vitamins Ltd)) | |
| Xenical Capsule, hard 120 mg (USV-Corvette (US Vitamins Ltd)) | |
| Xenical capsule 120 mg/1 (USV-Corvette (US Vitamins Ltd)) | |
| Xenical 120mg (Austria, Germany, Hungary, Luxembourg, Switzerland) | |
| Xenical 120mg hard capsules (United Kingdom) | |
| Xenical Bb Farma (Italy) | |
| Xenical Bcnfarma (Spain) | |
| Xenical D.A.C. (Iceland) | |
| Xenical Dark Blue | |
| Capsule; Oral; Orlistat 120 mg | |
| Xenical Difarmed (Spain) | |
| Xenical Generfarma (Spain) | |
| Xenical Gervasi (Spain) | |
| Xenical Programmi Sanitari (Italy) | |
| Xenical 賽尼可 (Hongkong) | |
| Xenical cap 120 mg 21's (Roche) | |
| Xenical cap 120 mg 42's (Roche) | |
| Xenical® | |
See 420 substitutes for Viplena | |
References
- DailyMed. "ORLISTAT: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "orlistat". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "orlistat". http://www.drugbank.ca/drugs/DB01083 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Viplena are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Viplena. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
