Vitamin D3 Uses

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What is Vitamin D3?

Vitamin D3 is a vitamin D3. Vitamin D is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.

Vitamin D3 is used to treat or prevent many conditions caused by a lack of vitamin D, especially conditions of the skin or bones.

Vitamin D3 may also be used for purposes not listed in this medication guide.

Vitamin D3 indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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For the treatment of vitamin D deficiency or insufficiency, refractory rickets (vitamin D resistant rickets), familial hypophosphatemia and hypoparathyroidism, and in the management of hypocalcemia and renal osteodystrophy in patients with chronic renal failure undergoing dialysis. Also used in conjunction with calcium in the management and prevention of primary or corticosteroid-induced osteoporosis. (Vitamin D deficiency; osteoporosis;)

Uses of Vitamin D3 in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Vitamin D (ergocalciferol-D2, Vitamin D3-D3, alfacalcidol) is a fat-soluble vitamin that helps your body absorb calcium and phosphorus. Having the right amount of vitamin D, calcium, and phosphorus is important for building and keeping strong bones. Vitamin D is used to treat and prevent bone disorders (such as rickets, osteomalacia). Vitamin D is made by the body when skin is exposed to sunlight. Sunscreen, protective clothing, limited exposure to sunlight, dark skin, and age may prevent getting enough vitamin D from the sun.

Vitamin D with calcium is used to treat or prevent bone loss (osteoporosis). Vitamin D is also used with other medications to treat low levels of calcium or phosphate caused by certain disorders (such as hypoparathyroidism, pseudohypoparathyroidism, familial hypophosphatemia). It may be used in kidney disease to keep calcium levels normal and allow normal bone growth. Vitamin D drops (or other supplements) are given to breast-fed infants because breast milk usually has low levels of vitamin D.

How to use D3-50 Vitamin D3

Take vitamin D by mouth as directed. Vitamin D is best absorbed when taken after a meal but may be taken with or without food. Alfacalcidol is usually taken with food. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

If your doctor has prescribed this medication, take as directed by your doctor. Your dosage is based on your medical condition, amount of sun exposure, diet, age, and response to treatment.

Measure the liquid medication with the dropper provided, or use a medication-measuring spoon/device to make sure you have the correct dose. If you are taking the chewable tablet or wafers, chew the medication thoroughly before swallowing. Do not swallow whole wafers.

Certain medications (bile acid sequestrants such as cholestyramine/colestipol, mineral oil, orlistat) can decrease the absorption of vitamin D. Take your doses of these medications as far as possible from your doses of vitamin D (at least 2 hours apart, longer if possible). It may be easiest to take vitamin D at bedtime if you are also taking these other medications. Ask your doctor or pharmacist how long you should wait between doses and for help finding a dosing schedule that will work with all your medications.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day if you are taking it once a day. If you are taking this medication only once a week, remember to take it on the same day each week. It may help to mark your calendar with a reminder.

If your doctor has recommended that you follow a special diet (such as a diet high in calcium), it is very important to follow the diet to get the most benefit from this medication and to prevent serious side effects. Do not take other supplements/vitamins unless ordered by your doctor.

If you think you may have a serious medical problem, get medical help right away.

Vitamin D3 description

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Derivative of 7-dehydroxycholesterol formed by ultraviolet rays breaking of the C9-C10 bond. It differs from ergocalciferol in having a single bond between C22 and C23 and lacking a methyl group at C24. [PubChem]

Vitamin D3 dosage

Vitamin D3 Dosage

Applies to the following strength(s): 400 intl units/mL; 1000 intl units; 2000 intl units; 400 intl units; 5000 intl units; 50,000 intl units; 14,000 intl units; 10,000 intl units/mL; 4000 intl units; 5000 intl units/mL; 400 intl units/0.028 mL; 1000 intl units/drop; 10000 intl units; 25,000 intl units; 1000 intl units/10 mL

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Geriatric Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Vitamin D Insufficiency

600 to 2,000 international units, orally, once a day

Maximum dose: 4,000 international units per day

Usual Adult Dose for Vitamin D Deficiency

Initial dose:

50,000 international units, once a week, for 8 weeks

or

6,000 international units, once a day, for 8 weeks

Maintenance dose: 1,500 to 2,000 international units, once a day

Maximum dose: 10,000 international units per day

Comments:

-Target blood levels above 30 ng/mL of 25(OH)D.

Usual Adult Dose for Prevention of Falls

800 international units, orally, once a day

-1,500 to 2,000 international units, once a day, may be needed to achieve blood levels of 25(OH)D above 30 ng/mL.

Usual Geriatric Dose for Prevention of Fractures

Over 70 years: 800 to 2,000 international units, orally, once a day

Usual Pediatric Dose for Vitamin D Insufficiency

0 to 12 months: 400 international units once a day

1 to 18 years: 600 international units once a day

Maximum dose:

-Up to 6 months: 1,000 international units per day

-7 months to 1 year: 1,500 international units per day

-1 to 3 years: 2,500 international units per day

-4 to 8 years: 3,000 international units per day

-9 years and older: 4,000 international units per day

Usual Pediatric Dose for Vitamin D Deficiency

-Up to 1 year old: 2,000 international units, orally, once a day, for 6 weeks

or

50,000 international units, once a week, for 6 weeks

Maintenance dose: 400 to 1,000 international units per day

-1 to 18 years: 2,000 international units, orally, once a day for at least 6 weeks

or

50,000 international units, once a week, for at least 6 weeks

Maintenance dose: 600 to 1,000 international units per day

Maximum dose:

-Up to 1 year: 2,000 international units per day

-1 to 18 years: 4,000 international units per day

Comments:

-Target blood levels above 30 ng/mL of 25(OH)D.

Renal Dose Adjustments

Do not use in severe renal impairment

Liver Dose Adjustments

Data not available

Dose Adjustments

Pregnancy or Lactation: 600 to 2,000 international units once a day; maximum 4,000 international units per day

-1,500 to 2,000 international units, once a day, may be needed to achieve blood levels of 25(OH)D above 30 ng/mL.

Obesity, Malabsorption Syndromes, or Medications Affecting Vitamin D Absorption:

-Treatment of Deficiency: 6,000 to 10,000 international units, once a day, until blood levels of 25(OH)D are above 30 ng/mL.

-Maintenance dose: 1,500 to 2,000 international units, once a day

Patients on anticonvulsants, glucocorticoids, antifungals such as ketoconazole, or medications for acquired immune deficiency syndrome may require 2 to 3 times more vitamin D.

Provide medical supervision if upper limits are exceeded.

Dialysis

Vitamin D and its metabolites are not dialyzable.

More about Vitamin D3

Consumer resources

Professional resources

Related treatment guides

Vitamin D3 interactions

See also:
What other drugs will affect Vitamin D3?

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Interactions for vitamin D analogues (Vitamin D2, Vitamin D3, Calcitriol, and Calcidiol)

Cholestyramine

Cholestyramine has been reported to reduce intestinal absorption of fat soluble vitamins; as such it may impair intestinal absorption of any of vitamin D

Phenytoin/Phenobarbital

The coadministration of phenytoin or phenobarbital will not affect plasma concentrations of vitamin D, but may reduce endogenous plasma levels of calcitriol/ergocalcitriol by accelerating metabolism. Since blood level of calcitriol/ergocalcitriol will be reduced, higher doses of Rocaltrol may be necessary if these drugs are administered simultaneously

Thiazides

Thiazides are known to induce hypercalcemia by the reduction of calcium excretion in urine. Some reports have shown that the concomitant administration of thiazides with vitamin D causes hypercalcemia. Therefore, precaution should be taken when coadministration is necessary

Digitalis

Vitamin D dosage must be determined with care in patients undergoing treatment with digitalis, as hypercalcemia in such patients may precipitate cardiac arrhythmias

Ketoconazole

Ketoconazole may inhibit both synthetic and catabolic enzymes of vitamin D. Reductions in serum endogenous vitamin D concentrations have been observed following the administration of 300 mg/day to 1200 mg/day ketoconazole for a week to healthy men. However, in vivo drug interaction studies of ketoconazole with vitamin D have not been investigated

Corticosteroids

A relationship of functional antagonism exists between vitamin D analogues, which promote calcium absorption, and corticosteroids, which inhibit calcium absorption

Phosphate-Binding Agents

Since vitamin D also has an effect on phosphate transport in the intestine, kidneys and bones, the dosage of phosphate-binding agents must be adjusted in accordance with the serum phosphate concentration

Vitamin D

The coadministration of any of the vitamin D analogues should be avoided as this could create possible additive effects and hypercalcemia

Calcium Supplements

Uncontrolled intake of additional calcium-containing preparations should be avoided

Magnesium

Magnesium-containing preparations (eg, antacids) may cause hypermagnesemia and should therefore not be taken during therapy with vitamin D by patients on chronic renal dialysis.

Vitamin D3 side effects

See also:
What are the possible side effects of Vitamin D3?

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Applies to Vitamin D3: oral capsule, oral capsule liquid filled, oral solution, oral tablet, oral tablet chewable, oral wafer

In addition to its needed effects, some unwanted effects may be caused by Vitamin D3 (the active ingredient contained in Vitamin D3). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking Vitamin D3:

Incidence not known:

Vitamin D3 contraindications

See also:
What is the most important information I should know about Vitamin D3?

Contraindications for vitamin D analogues (Vitamin D2, Vitamin D3, Calcitriol, and Calcidiol)

Vitamin D should not be given to patients with hypercalcemia or evidence of vitamin D toxicity. Use of vitamin D in patients with known hypersensitivity to vitamin D (or drugs of the same class) or any of the inactive ingredients is contraindicated.



Active ingredient matches for Vitamin D3:

Cholecalciferol in Germany, Switzerland.

Colecalciferol in Germany.


Unit description / dosage (Manufacturer)Price, USD
Tablet; Oral; Vitamin D3 / Cholecalciferol 1, 000 units
Drops; Oral; Vitamin D3 / Cholecalciferol 4000 IU / ml
Injectable; Injection; Vitamin D3 / Cholecalciferol 300, 000 IU / ml
Tablet; Oral; Vitamin D3 / Cholecalciferol
Drops; Oral; Vitamin D3 / Cholecalciferol
Capsule; Oral; Vitamin D3 / Cholecalciferol 1, 000 units

List of Vitamin D3 substitutes (brand and generic names):

Vitamine D3 B.O.N 5 mg x 1 tube x 1 mL
Injectable; Injection; Vitamin D3 / Cholecalciferol 5 mg / ml
Vitamix Vitamin A palmitate 3000 IU, Cholecalciferol 400 IU, Ascorbic acid 40 mg, Thiaminemononitrate 2 mg, riboflavin 1mg, nicotinamide 10.5 mg, pyridoxine hydrochloride 1 mg, D-panthenol 3 mg, alphatocopheryl acetate 5.25 IU/0.6mL. DPS / 30ml (Plus India)$ 0.79
30ml (Plus India)$ 0.79
Vitamix (Plus India)
Vitamix 15 ml Drop (Plus India)$ 0.02
VITAMIX oral drops 30ml (Plus India)$ 0.79
Vitamore Drop Vitamin A palmitate 1500 IU, thiamine hydrochloride 1 mg, riboflavin 1 mg, pyridoxine0.5 mg, cyanocobalamin 2 mg, ascorbic acid 20 mg, cholecalciferol 200 IU, tocopherol 5 mcg, folic acid10 mcg, zinc sulphate 2 mg, magnesium sulphate 0.7 mg, copper$ 0.63
Vitamore Drop Vitamin A palmitate 1500 IU, thiamine hydrochloride 1 mg, riboflavin 1 mg, pyridoxine0.5 mg, cyanocobalamin 2 mg, ascorbic acid 20 mg, cholecalciferol 200 IU, tocopherol 5 mcg, folic acid10 mcg, zinc sulphate 2 mg, magnesium sulphate 0.7 mg, copper$ 0.63
Vitamore Drop Vitamin A palmitate 1500 IU, thiamine hydrochloride 1 mg, riboflavin 1 mg, pyridoxine0.5 mg, cyanocobalamin 2 mg, ascorbic acid 20 mg, cholecalciferol 200 IU, tocopherol 5 mcg, folic acid10 mcg, zinc sulphate 2 mg, magnesium sulphate 0.7 mg, copper$ 0.63
Vitamore Drop Vitamin A palmitate 1500 IU, thiamine hydrochloride 1 mg, riboflavin 1 mg, pyridoxine0.5 mg, cyanocobalamin 2 mg, ascorbic acid 20 mg, cholecalciferol 200 IU, tocopherol 5 mcg, folic acid10 mcg, zinc sulphate 2 mg, magnesium sulphate 0.7 mg, copper$ 0.63
Vitamore Drop Vitamin A palmitate 1500 IU, thiamine hydrochloride 1 mg, riboflavin 1 mg, pyridoxine0.5 mg, cyanocobalamin 2 mg, ascorbic acid 20 mg, cholecalciferol 200 IU, tocopherol 5 mcg, folic acid10 mcg, zinc sulphate 2 mg, magnesium sulphate 0.7 mg, copper$ 0.63
VITANOVA-D3 dispertab 1000 IU x 10's (Zuventus)$ 0.51
Vitanova-SG 60000IU SG-CAP / 10 (Zuventus)$ 3.97
VITANOVA-SG soft-gelatin cap 60000 IU x 4's (Zuventus)$ 1.67
Vitarich SYR Vitamin A palmitate 1250 IU, cholecalciferol 100 IU, vitamin E 2.5 IU, thiaminehydrochloride 0.75 mg, potassium iodide 50 mcg, riboflavin sodium phosphate0.75 mg, pyridoxinehydrochloride 0.5 mg, cyanocobalamin 0.5 mcg, nicotinamide 7.5 mg, D-panthen (Saga Lab)$ 0.87
200ml (Saga Lab)$ 0.87
Vitarich Syr Vitamin A palmitate 1250 IU, cholecalciferol 100 IU, vitamin E 2.5 IU, thiaminehydrochloride 0.75 mg, potassium iodide 50 mcg, riboflavin sodium phosphate0.75 mg, pyridoxinehydrochloride 0.5 mg, cyanocobalamin 0.5 mcg, nicotinamide 7.5 mg, D-panthen (Saga Lab)$ 0.87
Vitarich SYR Vitamin A palmitate 1250 IU, cholecalciferol 100 IU, vitamin E 2.5 IU, thiaminehydrochloride 0.75 mg, potassium iodide 50 mcg, riboflavin sodium phosphate0.75 mg, pyridoxinehydrochloride 0.5 mg, cyanocobalamin 0.5 mcg, nicotinamide 7.5 mg, D-panthen (Saga Lab)$ 0.87
Vitarich Syr Vitamin A palmitate 1250 IU, cholecalciferol 100 IU, vitamin E 2.5 IU, thiaminehydrochloride 0.75 mg, potassium iodide 50 mcg, riboflavin sodium phosphate0.75 mg, pyridoxinehydrochloride 0.5 mg, cyanocobalamin 0.5 mcg, nicotinamide 7.5 mg, D-panthen (Saga Lab)$ 0.87
Vitarich SYR Vitamin A palmitate 1250 IU, cholecalciferol 100 IU, vitamin E 2.5 IU, thiaminehydrochloride 0.75 mg, potassium iodide 50 mcg, riboflavin sodium phosphate0.75 mg, pyridoxinehydrochloride 0.5 mg, cyanocobalamin 0.5 mcg, nicotinamide 7.5 mg, D-panthen (Saga Lab)$ 0.87
Vitarich Syr Vitamin A palmitate 1250 IU, cholecalciferol 100 IU, vitamin E 2.5 IU, thiaminehydrochloride 0.75 mg, potassium iodide 50 mcg, riboflavin sodium phosphate0.75 mg, pyridoxinehydrochloride 0.5 mg, cyanocobalamin 0.5 mcg, nicotinamide 7.5 mg, D-panthen (Saga Lab)$ 0.87
Vitarich SYR Vitamin A palmitate 1250 IU, cholecalciferol 100 IU, vitamin E 2.5 IU, thiaminehydrochloride 0.75 mg, potassium iodide 50 mcg, riboflavin sodium phosphate0.75 mg, pyridoxinehydrochloride 0.5 mg, cyanocobalamin 0.5 mcg, nicotinamide 7.5 mg, D-panthen (Saga Lab)$ 0.87
Vitarich Syr Vitamin A palmitate 1250 IU, cholecalciferol 100 IU, vitamin E 2.5 IU, thiaminehydrochloride 0.75 mg, potassium iodide 50 mcg, riboflavin sodium phosphate0.75 mg, pyridoxinehydrochloride 0.5 mg, cyanocobalamin 0.5 mcg, nicotinamide 7.5 mg, D-panthen (Saga Lab)$ 0.87
VITARICH SYR syr 200ml (Saga Lab)$ 0.87
Vitarich Syr Vitamin A palmitate 1250 IU, cholecalciferol 100 IU, vitamin E 2.5 IU, thiaminehydrochloride 0.75 mg, potassium iodide 50 mcg, riboflavin sodium phosphate0.75 mg, pyridoxinehydrochloride 0.5 mg, cyanocobalamin 0.5 mcg, nicotinamide 7.5 mg, D-panthen (Saga Lab)$ 0.87
Vitarich Syr Vitamin A palmitate 1250 IU, cholecalciferol 100 IU, vitamin E 2.5 IU, thiaminehydrochloride 0.75 mg, potassium iodide 50 mcg, riboflavin sodium phosphate0.75 mg, pyridoxinehydrochloride 0.5 mg, cyanocobalamin 0.5 mcg, nicotinamide 7.5 mg, D-panthen (Saga Lab)$ 0.87
Vitarich SYR Vitamin A palmitate 1250 IU, cholecalciferol 100 IU, vitamin E 2.5 IU, thiaminehydrochloride 0.75 mg, potassium iodide 50 mcg, riboflavin sodium phosphate0.75 mg, pyridoxinehydrochloride 0.5 mg, cyanocobalamin 0.5 mcg, nicotinamide 7.5 mg, D-panthen (Saga Lab)$ 0.87

References

  1. DailyMed. "ASCORBIC ACID; BIOTIN; CHOLECALCIFEROL; CYANOCOBALAMIN; DEXPANTHENOL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE; RIBOFLAVIN; THIAMINE; TOCOPHEROL ACETATE; VITAMIN A; VITAMIN K: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "CHOLECALCIFEROL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. PubChem. "cholecalciferol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Vitamin D3 are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Vitamin D3. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

2 consumers reported useful

Was the Vitamin D3 drug useful in terms of decreasing the symptom or the disease?
According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
Users%
Useful2
100.0%


Consumer reported price estimates

No survey data has been collected yet


1 consumer reported time for results

To what extent do I have to use Vitamin D3 before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 3 days and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Vitamin D3. To get the time effectiveness of using Vitamin D3 drug by other patients, please click here.
Users%
3 days1
100.0%


3 consumers reported age

Users%
30-451
33.3%
6-151
33.3%
46-601
33.3%


Consumer reviews


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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