Dosage of Yarizine in details
Yarizine Dosage
Applies to the following strength(s): 10 mg; 5 mg; 1 mg/mL
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual Adult Dose for:
- Allergic Rhinitis
- Urticaria
Usual Pediatric Dose for:
- Allergic Rhinitis
- Urticaria
Additional dosage information:
- Renal Dose Adjustments
- Liver Dose Adjustments
- Precautions
- Dialysis
Usual Adult Dose for Allergic Rhinitis
5 to 10 mg orally or chewed once a day
Usual Adult Dose for Urticaria
5 to 10 mg orally or chewed once a day
Usual Pediatric Dose for Allergic Rhinitis
6 months to 2 years: 2.5 mg orally once a day, 12 months and older may be increased to 2.5 mg orally twice a day.
2 to 5 years: 2.5 mg orally once a day, may be increased to 5 mg/day in 1 to 2 divided doses.
6 years or older: 5 to 10 mg orally or chewed once a day.
Usual Pediatric Dose for Urticaria
6 months to 2 years: 2.5 mg orally once a day, 12 months and older may be increased to 2.5 mg orally twice a day.
2 to 5 years: 2.5 mg orally once a day, may be increased to 5 mg/day in 1 to 2 divided doses.
6 years or older: 5 to 10 mg orally or chewed once a day.
Renal Dose Adjustments
CrCl less than 30 mL/min: 5 mg orally or chewed once a day.
Use of Yarizine is not recommended in children under 6 years of age with renal impairment due to the difficulty in reliably administering doses less than 2.5 mg (1/2 teaspoonful) and the lack of pharmacokinetic and safety information of Yarizine in such patients.
Liver Dose Adjustments
5 mg orally or chewed once a day
Use of Yarizine is not recommended in children under 6 years of age with hepatic impairment due to the difficulty in reliably administering doses less than 2.5 mg (1/2 teaspoonful) and the lack of pharmacokinetic and safety information of Yarizine in such patients.
Precautions
In clinical trials, the occurrence of somnolence has been reported. Due caution should therefore be exercised when driving a car or operating potential dangerous machinery. Concurrent use of alcohol or other CNS depressants should be avoided because additional reductions in alertness and additional impairment of CNS performance may occur.
Dialysis
Yarizine is not significantly removed by hemodialysis, thus supplementary dosing is not required following hemodialysis. The recommended dosage for patients on hemodialysis is 5 mg orally or chewed once a day.
More about Yarizine
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- 139 Reviews - Add your own review/rating
Consumer resources
- Yarizine
- Yarizine chewable tablets
- Yarizine orally disintegrating tablets
- Yarizine solution
- Other brands: Zyrtec, Children's Zyrtec, Zyrtec Hives, Yarizine, More (1) »
Professional resources
- Yarizine Hydrochloride (AHFS Monograph)
- More (8) »
Related treatment guides
- Allergic Rhinitis
- Urticaria
What other drugs will affect Yarizine?
Tell your doctor if you regularly use other medicines that make you sleepy (such as other cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by Yarizine.
This list is not complete and other drugs may interact with Yarizine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Yarizine interactions
Tablet: Concurrent use with alcohol may potentiate the CNS depressant effects of Yarizine; maprotiline or tricyclic antidepressants may potentiate the anticholinergic effects of either these medications or Yarizine.
Monoamine oxidase (MAO) inhibitors are not recommended because the use may prolong and intensify the anticholinergic and CNS depressant effects of Yarizine.
Concurrent use with ototoxic medications may mask the symptoms of ototoxicity eg, tinnitus, dizziness or vertigo; photosensitizing medications may cause additive photosensitizing effects.
Syrup: No interaction is observed for Yarizine with pseudoephedrine, cimetidine, ketoconazole, erythromycin and azithromycin. Small decrease in Yarizine clearance is observed when theophylline (400 mg once daily) is taken with Yarizine. However, disposition of theophylline was not altered by concomitant Yarizine administration. Concomitant administration of Yarizine and macrolides or ketoconazole has never resulted clinically relevant EGG changes. Extent of exposure to Yarizine was increased by 40% when ritonavir is taken with Yarizine. Disposition of ritonavir was slightly altered further to concomitant Yarizine administration.
References
- DailyMed. "CETIRIZINE HYDROCHLORIDE; PSEUDOEPHEDRINE HYDROCHLORIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- MeSH. "Anti-Allergic Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
- European Chemicals Agency - ECHA. "2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]acetic acid: The information provided here is aggregated from the "Notified classification and labelling" from ECHA's C&L Inventory. ". https://echa.europa.eu/information-o... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Yarizine are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Yarizine. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
