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What is Zanidion?
Relieving mild to moderately severe pain. It may also be used for other conditions as determined by your doctor.
Zanidion/ Codeine (Zanidion) is a narcotic and analgesic/antipyretic combination. It works in the brain and nervous system to decrease pain.
Zanidion (acetaminophen and Codeine (Zanidion) phosphate tablets) is indicated for the relief of mild to moderately severe pain.
How should I use Zanidion?
Use Zanidion/ Codeine (Zanidion) as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Zanidion/ Codeine (Zanidion) by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
- If you have been taking Zanidion/ Codeine (Zanidion) regularly or for longer than a few weeks, do not suddenly stop taking it without checking with your doctor. Your doctor may need to gradually lower your dose.
- If you miss a dose of Zanidion/ Codeine (Zanidion) and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Zanidion/ Codeine (Zanidion).
Dosage should be adjusted according to severity of pain and response of the patient.
The usual adult dosage is:
|Single Doses (Range)||Maximum 24 Hour Dose|
|Codeine (Zanidion) Phosphate||15 mg to 60 mg||360 mg|
|Acetaminophen||300 mg to 1000 mg||4000 mg|
The usual dose of Codeine (Zanidion) phosphate in children is 0.5 mg/kg.
Doses may be repeated up to every 4 hours.
The prescriber must determine the number of tablets per dose, and the maximum number of tablets per 24 hours based upon the above dosage guidance. This information should be conveyed in the prescription.
It should be kept in mind, however, that tolerance to Codeine (Zanidion) can develop with continued use and that the incidence of untoward effects is dose related. Adult doses of Codeine (Zanidion) higher than 60 mg fail to give commensurate relief of pain but merely prolong analgesia and are associated with an appreciably increased incidence of undesirable side effects. Equivalently high doses in children would have similar effects.
It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you take this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.
You should not take other medicines that contain Paracetamol (Zanidion) in combination with this medicine, as this can easily result in exceeding the maximum recommended daily dose of Paracetamol (Zanidion). Many cold and flu remedies and over-the-counter painkillers contain Paracetamol (Zanidion), so be sure to check the ingredients of any other medicines before taking them with this one. Zanidion yellow can be taken four hours after taking Zanidion pink if you still have a migraine, but make sure you do not exceed the maximum dose recommended in the information leaflet.
This medicine should be used with caution in people taking a monoamine oxidase inhibitor (MAOI), for example the antidepressants phenelzine, tranylcypromine or isocarboxacid. Ask your doctor or pharmacist for advice before taking this medicine if you have taken an MAOI in the last 14 days.
Cholestyramine reduces the absorption of Paracetamol (Zanidion) from the gut. It should not be taken within an hour of taking Paracetamol (Zanidion) or the effect of the Paracetamol (Zanidion) will be reduced.
Metoclopramide and domperidone may increase the absorption of Paracetamol (Zanidion) from the gut.
Long-term or regular use of Paracetamol (Zanidion) may increase the anti-blood-clotting effect of warfarin and other anticoagulant medicines, leading to an increased risk of bleeding. This effect does not occur with occasional painkilling doses. If you are taking an anticoagulant medicine and you are also taking co-codamol regularly, your blood clotting time (INR) should be regularly monitored.
In the unlikely event that this medicine makes you feel drowsy, this may be enhanced by other medicines that can cause drowsiness, such as the following:
antipsychotics, eg haloperidol
barbiturates, eg phenobarbital, amobarbital
benzodiazepines, eg diazepam, temazepam
other opioids, eg morphine, dihydrocodeine
sedating antihistamines, eg chlorphenamine, hydroxyzine
sleeping tablets, eg zopiclone
tricyclic antidepressants, eg amitriptyline.
Zanidion side effects
dizziness, light-headedness, feeling, faint, sleepiness, nausea or vomiting, vision disturbance, unusual tiredness or weakness, insomnia, constipation, stomach cramps, painful urination, redness or swelling at the place of injection, nightmares, a false sense of well-being, dry mouth, headache, or malaise. You may also experience the less common side effects of dark urine, bloody, black or tarry stools, white spots on lips or mouth, sore throat, pain in your lower back or side, jaundice, irregular heartbeat, restlessness, tremor or uncontrolled movements, sweating, irregular breathing, facial swelling, ringing in the ears, flushing, depression or mood swings, pale stools, or hallucinations. Taking too much Zanidion can be dangerous, and you should get emergency help immediately if you experience cold or clammy skin, severe weakness, confusion, slow heartbeat, severe drowsiness, pinpoint pupils, low blood pressure, liver or kidney damage, or severe restlessness or nervousness.
Decreased kidney function.
Decreased liver function.
Children under 10 years of age, unless on the advice of a doctor.
This medicine should not be used if you are allergic to any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Active ingredient matches for Zanidion:
Codeine/Paracetamol in Vietnam.
|Unit description / dosage (Manufacturer)||Price, USD|
|Zanidion 5 Blister x 10 Tablet|
|Zanidion 10 Blister x 10 Tablet|
List of Zanidion substitutes (brand and generic names):
|Tachidol Bambini (Italy)|
|Talgo Codeina (Spain)|
|Talvosilen (Czech Republic, Germany, Poland)|
|Capsule; Oral; Acetaminophen; Codeine Phosphate|
|Suppositories; Rectal; Acetaminophen 1000 mg; Codeine Phosphate|
|Suppositories; Rectal; Acetaminophen 250 mg; Codeine Phosphate|
|Suppositories; Rectal; Acetaminophen 500 mg; Codeine Phosphate|
|Suspension; Oral; Acetaminophen; Codeine Phosphate|
|Tablet; Oral; Acetaminophen; Codeine Phosphate|
|Talvosilen Forte (Germany)|
|Capsule; Oral; Acetaminophen; Codeine Phosphate|
|Suppositories; Rectal; Acetaminophen; Codeine Phosphate|
|Talvosilen Forte 500 mg/30 mg (Hungary)|
|talvosilen für Kleinkinder (Germany)|
|talvosilen für Schulkinder (Germany)|
|Tatanol Codein (Vietnam)|
|Tatanol Codein 20 Blister x 4 Tablet|
|Termaldina Codeina (Spain)|
|Termalgin Codeina (Spain)|
|Tablet; Oral; Acetaminophen 300 mg; Codeine Phosphate 30 mg|
|Twc 325+30 Tablet (Johnson & Johnson)||$ 0.18|
|Tylenol w/ Codeine (United States)|
|Tylenol with Codeine (Canada, Thailand, United States)|
|Elixir; Oral; Acetaminophen 160 mg; Codeine Phosphate 8 mg / 5 ml|
|Solution; Oral; Acetaminophen 120 mg; Codeine Phosphate 12 mg / 5 ml|
|Tablet; Oral; Acetaminophen 325 mg; Codeine Phosphate 15 mg|
|Tablet; Oral; Acetaminophen 325 mg; Codeine Phosphate 30 mg|
|Tablet; Oral; Acetaminophen 325 mg; Codeine Phosphate 60 mg|
|Tablet; Oral; Acetaminophen 325 mg; Codeine Phosphate 7.5 mg|
|Tylenol With Codeine 50 x 10's|
|Tylex CD (Mexico, Venezuela)|
|Capsule; Oral; Codeine Phosphate Hemihydrate 30 mg; Acetaminophen 500 mg|
|Ultracod (Czech Republic, Latvia, Lithuania, Poland, Slovakia)|
|Uphamol Plus Codeine (Malaysia)|
|Uphamol Plus Codeine 50 x 10's|
|Vadol Codein (Vietnam)|
|Vadol Codein 10 Blister x 10 Tablet|
|Vadol Codein 1 Bottle 100 Tablet|
|Vopac (United States)|
|Winadeine F (Ecuador)|
|Winadol Forte (Colombia)|
|Your Pharmacy Paracetamol Plus (New Zealand)|
|Zapain (Malta, United Kingdom)|
- DailyMed. "CODEINE SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "codeine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "codeine". http://www.drugbank.ca/drugs/DB00318 (accessed September 17, 2018).
ReviewsThe results of a survey conducted on ndrugs.com for Zanidion are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Zanidion. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
Consumer reported usefulNo survey data has been collected yet
Consumer reported price estimatesNo survey data has been collected yet
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Information checked by Dr. Sachin Kumar, MD Pharmacology