Amoxin Uses

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What is Amoxin?

Penicillins are used to treat infections caused by bacteria. They work by killing the bacteria or preventing their growth.

There are several different kinds of penicillins. Each is used to treat different kinds of infections. One kind of penicillin usually may not be used in place of another. In addition, penicillins are used to treat bacterial infections in many different parts of the body. They are sometimes given with other antibacterial medicines (antibiotics). Some of the penicillins may also be used for other problems as determined by your doctor. However, none of the penicillins will work for colds, flu, or other virus infections.

Penicillins are available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, penicillins are used in certain patients with the following medical conditions:

Amoxin indications

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Infections of the Ear, Nose, and Throat

Amoxin, Amoxin for oral suspension, Amoxin tablets (chewable) are indicated in the treatment of infections due to susceptible (ONLY β-lactamase–negative) isolates of Streptococcus species (α- and β-hemolytic isolates only), Streptococcus pneumoniae, Staphylococcus spp., or Haemophilus influenzae.

Infections of the Genitourinary Tract

Amoxin, Amoxin for oral suspension, Amoxin tablets (chewable) are indicated in the treatment of infections due to susceptible (ONLY β-lactamase–negative) isolates of Escherichia coli, Proteus mirabilis, or Enterococcus faecalis.

Infections of the Skin and Skin Structure

Amoxin, Amoxin for oral suspension, Amoxin tablets (chewable) are indicated in the treatment of infections due to susceptible (ONLY β-lactamase-negative) isolates of Streptococcus spp. (α- and β-hemolytic isolates only), Staphylococcus spp., or E. coli.

Infections of the Lower Respiratory Tract

Amoxin, Amoxin for oral suspension, Amoxin tablets (chewable) are indicated in the treatment of infections due to susceptible (ONLY β-lactamase-negative) isolates of Streptococcus spp. (α- and β-hemolytic isolates only), S. pneumoniae, Staphylococcus spp., or H. influenzae.

Helicobacter pylori Infection

Triple therapy for Helicobacter pylori with clarithromycin and lansoprazole:

Amoxin, in combination with clarithromycin plus lansoprazole as triple therapy, is indicated for the treatment of patients with H. pylori infection and duodenal ulcer disease (active or 1 year history of a duodenal ulcer) to eradicate H. pylori. Eradication of H. pylori has been shown to reduce the risk of duodenal ulcer recurrence.

Dual therapy for H. pylori with lansoprazole:

Amoxin, in combination with lansoprazole delayed-release capsules as dual therapy, is indicated for the treatment of patients with H. pylori infection and duodenal ulcer disease (active or 1 year history of a duodenal ulcer) who are either allergic or intolerant to clarithromycin or in whom resistance to clarithromycin is known or suspected. Eradication of H. pylori has been shown to reduce the risk of duodenal ulcer recurrence.

Usage

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Amoxin and other antibacterial drugs, Amoxin should be used only to treat infections that are proven or strongly suspected to be caused by bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

How should I use Amoxin?

Use Amoxin suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Amoxin suspension.

Uses of Amoxin in details

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Use: Labeled Indications

Ear, nose, and throat infections (pharyngitis/tonsillitis, otitis media):

Immediate release: Treatment of infections due to beta-lactamase-negative Streptococcus spp. (alpha- and beta-hemolytic isolates only), Streptococcus pneumoniae, Staphylococcus spp., or Haemophilus influenzae.

Extended release: Treatment of tonsillitis and/or pharyngitis due to Streptococcus pyogenes in adults and pediatric patients ≥12 years of age.

Genitourinary tract infections: Immediate release: Treatment of infections of the genitourinary tract due to beta-lactamase-negative Escherichia coli, Proteus mirabilis, or Enterococcus faecalis.

Helicobacter pylori eradication: Immediate release: Eradication of H. pylori to reduce the risk of duodenal ulcer recurrence as a component of combination therapy in patients with active or 1-year history of duodenal ulcer disease.

Lower respiratory tract infections (including pneumonia): Immediate release: Treatment of infections of the lower respiratory tract due to beta-lactamase-negative Streptococcus spp. (alpha- and beta-hemolytic strains only), S. pneumoniae, Staphylococcus spp., or H. influenzae.

Rhinosinusitis, acute bacterial: Immediate release: Treatment of infections due to beta-lactamase-negative Streptococcus spp. (alpha- and beta-hemolytic isolates only), S. pneumoniae, Staphylococcus spp., or H. influenzae.

Skin and skin structure infections: Immediate release: Treatment of infections of the skin and skin structure due to beta-lactamase-negative Streptococcus spp. (alpha- and beta-hemolytic strains only), Staphylococcus spp., or E. coli.

Off Label Uses

Actinomycosis

Data from a small retrospective study suggest that Amoxin may be beneficial for the treatment of actinomycosis.

Prosthetic joint infection

Based on the IDSA guidelines for the management of prosthetic joint infection (PJI), Amoxin is an effective and recommended agent for chronic oral antimicrobial suppression of PJI with beta-hemolytic streptococci, Enterococcus spp. (penicillin susceptible), and Cutibacterium spp. after completion of parenteral therapy.

Amoxin description

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A broad-spectrum semisynthetic antibiotic similar to ampicillin except that its resistance to gastric acid permits higher serum levels with oral administration. Amoxin is commonly prescribed with clauvanic acid (a beta lactamase inhibitor) as it is susceptible to beta-lacatamase degradation. [PubChem]

Amoxin dosage

Amoxin Dosage

Generic name: Amoxin 775mg

Dosage form: tablet, film coated, extended release

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Tonsillitis and/or Pharyngitis

The recommended dose of Amoxin is 775 mg once daily taken within 1 hour of finishing a meal for 10 days. The full 10-day course of therapy should be completed for effective treatment of tonsillitis and/or pharyngitis secondary to S. pyogenes.

Do not chew or crush tablet.

More about Amoxin (Amoxin)

Consumer resources

Professional resources

Related treatment guides

Amoxin interactions

See also:
What other drugs will affect Amoxin?

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Allopurinol: Concurrent administration may increase the incidence of rash and other allergic skin reactions.

Anticoagulants: There are rare reports of prolongation of prothrombin time in patients concomitantly on Amoxin. It is recommended that appropriate monitoring is carried out when Amoxin is prescribed concurrently with anticoagulants.

Oral Contraceptives:

In common with other antibiotics, Amoxin may affect the gut flora, leading to lower oestrogen reabsorption and reduced efficacy of combined oral contraceptives.

Probenecid: Decreases the renal tubular secretion of Amoxin. Concurrent use with Amoxin may result in increased and prolonged blood levels of Amoxin.

Laboratory Tests: Glucose in Urine: Due to the high urinary concentrations of Amoxin, false positive readings are common with chemical methods.

The use of enzymatic glucose oxidase methods is recommended, as there is no interference from Amoxin.

Amoxin side effects

See also:
What are the possible side effects of Amoxin?

. Overdosage

In case of overdosage, discontinue medication, treat symptomatically, and institute supportive measures as required. If the overdosage is very recent and there is no contraindication, an attempt at emesis or other means of removal of drug from the stomach may be performed. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of Amoxin are not associated with significant clinical symptoms and do not require gastric emptying.3

Interstitial nephritis resulting in oliguric renal failure has been reported in a small number of patients after overdosage with Amoxin.

Crystalluria, in some cases leading to renal failure, has also been reported after Amoxin overdosage in adult and pediatric patients. In case of overdosage, adequate fluid intake and diuresis should be maintained to reduce the risk of Amoxin crystalluria.

Renal impairment appears to be reversible with cessation of drug administration. High blood levels may occur more readily in patients with impaired renal function because of decreased renal clearance of Amoxin. Amoxin may be removed from circulation by hemodialysis.

Amoxin contraindications

See also:
What is the most important information I should know about Amoxin?

Do not use this medication if you are allergic to Amoxin or to any other penicillin antibiotic, such as ampicillin (Principen, Unasyn), dicloxacillin (Dycill, Dynapen), oxacillin (Bactocill), or penicillin (Bicillin L-A, PC Pen VK, Pfizerpen), and others.

Before using Amoxin, tell your doctor if you are allergic to cephalosporins such as Omnicef, Cefzil, Ceftin, Keflex, and others. Also tell your doctor if you have asthma, liver or kidney disease, a bleeding or blood clotting disorder, mononucleosis (also called "mono"), or any type of allergy.

Amoxin can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom or diaphragm with spermicide) to prevent pregnancy while taking Amoxin.

Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Amoxin will not treat a viral infection such as the common cold or flu.

Do not share this medication with another person, even if they have the same symptoms you have.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking Amoxin and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.



Active ingredient matches for Amoxin:

Amoxicillin in Ethiopia, Finland, Germany, Kenya.

Amoxicillin trihydrate in Finland.

Amoxycillin trihydrate in Thailand.


Unit description / dosage (Manufacturer)Price, USD
Amoxin 250 mg x 500's
Amoxin 250 mg x 1, 000's
Amoxin 500 mg x 500's
Amoxin 500 mg x 1, 000's
Amoxin 125 mg/5 mL x 60 mL

List of Amoxin substitutes (brand and generic names):

Tablet, Film-Coated; Oral; Amoxicillin Trihydrate 750 mg (Cimex)
AMOXINGA Capsule/ Tablet / 500mg / 6 units (Inga)$ 0.45
AMOXINGA Liquid / 125mg per 5ml / 60ml units (Inga)$ 0.34
AMOXINGA Capsule/ Tablet / 250mg / 6 units (Inga)$ 0.26
AMOXINGA Capsule/ Tablet / 125mg / 10 units (Inga)$ 0.26
AMOXINGA Dispersible Tablet / 250mg / 15 units (Inga)$ 0.69
Amoxinga 250mg CAP / 6 (Inga)$ 0.27
Amoxinga 500mg CAP / 6 (Inga)$ 0.45
Amoxinga 125mg P-TAB / 10 (Inga)$ 0.26
Amoxinga 250mg DT-TAB / 15 (Inga)$ 0.69
250 mg x 6's (Inga)$ 0.27
500 mg x 6's (Inga)$ 0.45
125 mg x 10's (Inga)$ 0.26
250 mg x 15's (Inga)$ 0.69
AMOXINGA cap 250 mg x 6's (Inga)$ 0.27
AMOXINGA cap 500 mg x 6's (Inga)$ 0.45
AMOXINGA P- tab 125 mg x 10's (Inga)$ 0.26
AMOXINGA dispertab 250 mg x 15's (Inga)$ 0.69
Amoxinga SYR 125mg SYR / 60ml (Inga)$ 0.34
125 mg x 60ml (Inga)$ 0.34
AMOXINGA SYR syr 125 mg x 60ml (Inga)$ 0.34
Capsule; Oral; Amoxicillin Trihydrate 250 mg (Novag)
Capsule; Oral; Amoxicillin Trihydrate 500 mg (Novag)
Suspension; Oral; Amoxicillin Trihydrate 250 mg / 5 ml (Novag)
Suspension; Oral; Amoxicillin Trihydrate 500 mg / 5 ml (Novag)
AMOXIPEN Capsule/ Tablet / 250mg / 10 units (PCI)$ 0.47
AMOXIPEN Liquid / 125mg per 5ml / 60ml units (PCI)$ 0.40
AMOXIPEN Capsule/ Tablet / 500mg / 10 units (PCI)$ 0.88
AMOXIPEN Liquid / 250mg per 5ml / 30ml units (PCI)$ 0.34
AMOXIPEN Liquid / 125mg per 5ml / 30ml units (PCI)$ 0.22
Amoxipen 250mg CAP / 10 (PCI)$ 0.47
Amoxipen 500mg CAP / 10 (PCI)$ 0.88
Amoxipen 125mgx5mL SYR / 30ml (PCI)$ 0.22

References

  1. DailyMed. "AMOXICILLIN; CLAVULANATE POTASSIUM: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "amoxicillin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "amoxicillin". http://www.drugbank.ca/drugs/DB01060 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Amoxin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Amoxin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

1 consumer reported useful

Was the Amoxin drug useful in terms of decreasing the symptom or the disease?
According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
Users%
Useful1
100.0%


1 consumer reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Amoxin drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users%
Expensive1
100.0%


Consumer reported time for results

No survey data has been collected yet


4 consumers reported age

Users%
30-452
50.0%
16-291
25.0%
> 601
25.0%


Consumer reviews


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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