What is Paratropina?
Widening (dilating) the pupils for an eye exam or to treat certain inflammatory conditions of the eye. It may also be used for other conditions as determined by your doctor.
Paratropina drops is an anticholinergic agent. It works by blocking the chemical acetylcholine, which relaxes the ciliary muscle of the eye and causes the pupil to dilate.
Paratropina indications
Ophthalmic
Mydriasis and cycloplegia for refraction
Adult: Instill 1 or 2 drops of 2% solution, or 1 drop of 5% solution immediately before the procedure, repeat at 5-10-minute intervals if necessary.
Child: Instill 1 drop of 2% soln immediately before the procedure, repeat at 10-min intervals if necessary.
Ophthalmic
Uveitis
Adult: Instill 1-2 drops of 2% or 5% solution bid-tid up to every 3-4 hr as needed.
Child: 3 mth- 2 yr: instill 1 drop of 0.5% soln once daily or on alternate days. >2 yr: instill 1 drop of 1% or 2% soln bid.
How should I use Paratropina?
Use Paratropina drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Paratropina drops. Talk to your pharmacist if you have questions about this information.
- To use Paratropina drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
- To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
- If you miss a dose of Paratropina drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Paratropina drops.
Uses of Paratropina in details
Paratropina is used to widen the pupil before eye examination, before and after certain eye surgeries, and to treat certain eye conditions.
Paratropina description
Paratropina is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics. Paratropina is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be used to prevent nausea, vomiting, and motion sickness.
Paratropina dosage
Usual Adult Dose for Refraction
Instill 1 to 2 drops in the eye once. May repeat in 5 to 10 minutes if necessary. The lacrimal sacs should be compressed by digital pressure for a few minutes after instillation.
Usual Adult Dose for Uveitis
Instill 1 to 2 drops into the affected eye up to every 3 to 4 hours. The lacrimal sacs should be compressed by digital pressure for a few minutes after instillation.
Usual Pediatric Dose for Refraction
Only the 2% strength should be used in children:
Instill 1 to 2 drops in the eye once. May repeat in 5 to 10 minutes if necessary. The lacrimal sacs should be compressed by digital pressure for a few minutes after instillation.
Usual Pediatric Dose for Uveitis
Only the 2% strength should be used in children:
Instill 1 to 2 drops into the affected eye up to every 3 to 4 hours. The lacrimal sacs should be compressed by digital pressure for a few minutes after instillation.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Dialysis
Data not available
Paratropina interactions
When atropine and pralidoxime are used together, the signs of atropinization (flushing, mydriasis, tachycardia, dryness of the mouth and nose) may occur earlier than might be expected than when atropine is used alone because pralidoxime may potentiate the effect of atropine.
The following precautions should be kept in mind in the treatment of anticholinesterase poisoning although they do not bear directly on the use of atropine and pralidoxime. Since barbiturates are potentiated by the anticholinesterases, they should be used cautiously in the treatment of convulsions.
Paratropina side effects
See also:
What are the possible side effects of Paratropina?
Transient symptoms of stinging and burning may occur. Prolonged use may produce local irritation characterized by follicular conjunctivitis, vascular congestion, edema, exudate, and an eczematoid dermatitis. Thirst or dryness of mouth, eye irritation not present before therapy, or increased sensitivity of eyes to light may occur.
Overdose for Paratropina
Systemic Paratropina toxicity is manifested by flushing and dryness of the skin (a rash may be present in children), blurred vision, a rapid and irregular pulse, fever, abdominal distention in infants, mental aberration (hallucinosis) and loss of neuro-muscular coordination. Atropine poisoning, although distressing, is rarely fatal even with large doses of atropine, and is self-limited if the cause is recognized and the Paratropina medication is discontinued. Treatment includes supportive measures including maintaining a patent airway and assisting respiration if needed. Treat hyperthermia, coma and seizures if they occur (1). In infants and children, the body surface must be kept moist. Excitement may be controlled by diazepam or a short-acting barbiturate. For ingestion, activated charcoal can be used to prevent drug absorption. If necessary, ipecac or another cathartic may be useful for drug removal during initial treatment (1, 2). Physostigmine is used as an antidote to the systemic effects of atropine and may be administered parenterally to provide more prompt relief of intoxication.
Parenteral physostigmine may be particularly useful in cases of pronounced hallucinations, agitation in which a patient may be dangerous to himself or others, arrhythmias resulting in uncontrolled hemodynamic instability, and intractable seizures.
Paratropina contraindications
See also:
What is the most important information I should know about Paratropina?
Contraindicated in persons with primary glaucoma or a tendency toward glaucoma, e.g., narrow anterior chamber angle, and in those persons showing hypersensitivity to any component of this preparation.
Active ingredient matches for Paratropina:
Homatropine in Argentina.
Homatropine methylbromide in Argentina.
List of Paratropina substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Homatropine Methylbromide (Argentina) | |
| Isopto homatropine 2% drops | $ 5.57 |
| Homatropaire 5% eye drops | $ 3.82 |
| Homatropine hbr crystals | $ 2.69 |
| Hycodan tablet | $ 1.40 |
| Homatropine-OSL (Bangladesh) | |
| Homatropinehydrobromide Ratiopharm (Netherlands) | |
| Homogrin (Mexico) | |
| Humulon Lead Salt | |
| Hycodan, Probilagol | |
| Infafren Simple (Mexico) | |
| Isopto Homatropine 1% (France) | |
| Kolicon (Belize, Guatemala) | |
| Kotowi (Taiwan) | |
| Kotowi 2.5 mg | |
| Lesopen (Philippines) | |
| Lesopen 5 mg x 100's (Lejal) | $ 9.47 |
| Lesopen 5 mg/5 mL x 60 mL (Lejal) | $ 1.49 |
| Lesopen syr 5 mg/5 mL 60 mL x 1's (Lejal) | $ 1.49 |
| Lesopen tab 5 mg 100's (Lejal) | $ 9.47 |
| Litropina (Venezuela) | |
| Malcotran | |
| Matropin (Bangladesh) | |
| Mesopin | |
| Methyl Bromide Homatropine | |
| Methylhomatropine | |
| Methylhomatropine bromide | |
| Metilbromuro de Homatropina Veinfar (Uruguay) | |
| Minims Homatropine Hydrobromide | |
| Liquid; Ophthalmic; Homatropine Hydrobromide 2% | |
| Minims Homatropinhydrobromid (Austria) | |
| Liquid; Ophthalmic; Homatropine Hydrobromide 2% | |
| Novatrin | |
| Novatrine | |
| Novatropina (Brazil) | |
| Novatropine | |
| Npvatropine | |
| Omatropina (Italy) | |
| Omatropina Lux (Italy) | |
| Pingin (Taiwan) | |
| Pingin 2.5 mg | |
| Royadrin (Taiwan) | |
| Royadrin | |
| Royadrin Blister pk | |
| Sed-Tems | |
| Sedotropina (Peru) | |
| Sethyl | |
| Tropinium methobromide mandelate | |
See 89 substitutes for Paratropina | |
References
- DailyMed. "HOMATROPINE METHYLBROMIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "HOMATROPINE". https://pubchem.ncbi.nlm.nih.gov/sub... (accessed September 17, 2018).
- PubChem. "homatropine methylbromide". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Paratropina are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Paratropina. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yet1 consumer reported price estimates
Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?The below mentioned numbers have been reported by ndrugs.com website users about whether the Paratropina drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
| Users | % | ||
|---|---|---|---|
| Expensive | 1 | 100.0% | |
Consumer reported time for results
No survey data has been collected yetConsumer reported age
No survey data has been collected yetConsumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
