Amsiv indications
For use Max Pidek Pharmaceuticals as monotherapy and in combination with clavulanic acid: an infectious-inflammatory diseases caused by susceptible microorganisms, including bronchitis, pneumonia, tonsillitis, pyelonephritis, urethritis, infections of the gastrointestinal tract, gynecological infections, infections of the skin and soft tissue, listeria, leptospirosis, gonorrhea.
For use Max Pidek Pharmaceuticals in combination with metronidazole: chronic gastritis in acute, peptic ulcer and duodenal ulcer in acute, associated with Helicobacter Pylori.
Uses of Amsiv in details
Amsiv is used to treat certain diseases of the respiratory tract and to relieve cough associated with thickened mucous.
Amsiv description
Each retard capsule contains Ambroxol hydrochloride 75 mg.
Each tablet contains Ambroxol hydrochloride 30 mg.
Each 5 mL of syrup contains Ambroxol hydrochloride 15 or 30 mg.
Each mL of syrup (infant drops) contains Ambroxol hydrochloride 6 mg.
Amsiv hydrochloride is trans-4-[(2-amino-3,5-dibromo-benzyl)amino] cyclohexanol hydrochloride.
It also contains the following excipients: Retard Capsules: Crospovidone collidon CL, carnauba wax, stearyl alcohol, magnesium stearate.
Tablets: Lactose, maize starch, colloidal silica, magnesium stearate.
Syrup: Purified water, sorbitol liquid, glycerol 85%, woodberry aroma (15 mg only), strawberry aroma (30 mg only), hydroxyethylcellulose, benzoic acid, acesulfame potassium, vanilla aroma.
Infant Drops: Hydroxyethylcellulose, sorbitol solution, glycerol 85%, sodium saccharin, pharma flavors, menthol, benzoic acid, propylene glycol.
Amsiv dosage
Sustained-Release Capsule: Adults and Children >12 years: 1 cap once daily after meal with plenty of liquid (sufficient supply of liquid supports the expectorant effect of Amsiv).
Amsiv SR capsule is not suitable for children <12 years.
Tablet: Adults and Children >12 years: 1 tab thrice daily for the first 2-3 days and then 1 tab twice daily or ½ tab thrice daily. Children 6-12 years: ½ tab 2-3 times a day.
Syrup: Adults and Children >12 years: 10 mL thrice daily during the first 2-3 days, them 10 mL twice daily or 5 mL thrice daily. Children 6-12 years: 5 mL 2-3 times a day; 2-5 years: 2.5 mL 3 times a day; <2 years: 2.5 mL 2 times a day.
DS Syrup: Adults and Children >12 years: 5 mL thrice daily for 2-3 days then 5 mL twice daily for 2.5 mL thrice daily. Children 6-12 years: 2.5 mL 2-3 times a day.
Infant Drops: Children 13-24 months: 1.25 mL twice a day; 7-12 months: 1 mL twice a day; ≤6 months: 0.5 mL twice a day.
Amsiv interactions
Amoxicillin may decrease the effectiveness of contraceptives for oral administration.
With the simultaneous use of Max Pidek Pharmaceuticals with bactericidal antibiotics (including aminoglycosides, cephalosporins, cycloserine, vancomycin, rifampicin) appears synergies; with bacteriostatic antibiotic (including macrolides, chloramphenicol, lincosamides, tetracyclines, sulphonamide) - antagonism.
Amoxicillin increases the effects of indirect anticoagulants inhibiting intestinal microflora, reduces the synthesis of vitamin K and prothrombin index.
Amoxicillin reduces the effect of drugs, in the process of metabolism that produce PABA.
Probenecid, diuretics, allopurinol, phenylbutazone, NSAIDs decrease the tubular secretion of amoxicillin, which can be accompanied by an increase in its concentration in blood plasma.
Antacids, glucosamine, laxatives, aminoglycosides, slow down and reduce, and ascorbic acid increases the absorption of amoxicillin.
With the combined use of amoxicillin and clavulanic acid pharmacokinetics of both components unchanged.
Amsiv side effects
Allergic reactions: urticaria, erythema, edema Quincke, rhinitis, conjunctivitis, rarely - fever, joint pain, eosinophilia, in rare cases - anaphylactic shock.
Side effects associated with chemotherapy effect: possible development of super-infection (particularly in patients with chronic diseases or low resistance of the organism).
With prolonged use at high doses: dizziness, ataxia, confusion, depression, peripheral neuropathy, seizures.
Mostly when Max Pidek Pharmaceuticals used in combination with metronidazole: nausea, vomiting, anorexia, diarrhea, constipation, epigastric pain, glossitis, stomatitis; rarely - hepatitis, pseudomembranous colitis, allergic reactions (urticaria, angioedema), interstitial nephritis, a violation of hematopoiesis.
Mostly when Max Pidek Pharmaceuticals used in combination with clavulanic acid: cholestatic jaundice, hepatitis, rarely - erythema multiforme, toxic epidermal necrolysis, exfoliative dermatitis.
Amsiv contraindications
Hypersensitivity to Amsiv hydrochloride or to any other excipients of Amsiv.
In case of rare hereditary conditions that may be incompatible with an excipient of Amsiv, the use of Amsiv is contraindicated.
Active ingredient matches for Amsiv:
Ambroxol in Bangladesh.
List of Amsiv substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Amrox-GT (India) | |
| AMROX-GT oral drops 15ml (Systemic) | |
| Amsol (Taiwan) | |
| Amsol 30 mg x 1000's | |
| Amsol 30 mg x 100 x 10's | |
| Amsol-SR (India) | |
| Amsol-SR 75mg TAB / 10 (Kopran (Kresp)) | $ 0.42 |
| 75 mg x 10's (Kopran (Kresp)) | $ 0.42 |
| AMSOL-SR tab 75 mg x 10's (Kopran (Kresp)) | $ 0.42 |
| Amsovan (Taiwan) | |
| Amsovan 3 mg/1 mL x 1 mL | |
| Amsovan 3 mg/1 mL x 60 mL | |
| Amsovan 3 mg/1 mL x 120 mL | |
| Amtuss (Malaysia, Thailand) | |
| Amtuss 30 mg x 50 x 10's (Unison) | |
| Amtuss 30 mg/5 mL x 60 mL x 50's (Unison) | |
| Amtuss tab 30 mg 50 x 10's (Unison) | |
| Amtuss syr 30 mg/5 mL 60 mL x 1's (Unison) | |
| Amucap (Vietnam) | |
| Amucap 30 mg x 10 Blister x 10 Tablet | |
| Amunodin (Poland) | |
| Amxol (Hong Kong, Malaysia, Singapore, Taiwan, Thailand) | |
| Amxol 30 mg x 10 x 10's (Biolab) | $ 53.00 |
| Amxol 30 mg x 500's (Biolab) | |
| Amxol 30 mg/5 mL x 60 mL (Biolab) | |
| Amxol 3 mg/1 mL x 60 mL (Biolab) | |
| Amxol 3 mg/1 mL x 100 mL (Biolab) | |
| Amxol 3 mg/1 mL x 120 mL (Biolab) | |
| Amxol 30 mg/5 mL x 1 L (Biolab) | |
| Amxol 30 mg x 10 x 10's (Biolab) | |
| Amxol 30 mg/5 mL x 1000 mL x 1's (Biolab) | |
| Amxol syr 30 mg/5 mL 60 mL x 1's (Biolab) | |
| Amxol tab 30 mg 10 x 10's (Biolab) | |
| Amxol tab 30 mg 500's (Biolab) | |
| Amxol syr 30 mg/5 mL 1000 mL x 1's (Biolab) | |
| Amxol tab 30 mg 50 x 10's (Biolab) | |
| Amy (India) | |
| Amy Ambroxol 30mg, Guiaphenesin50mg, Loratadine 5mg/5mL EXPECTORANT / 60ml | $ 0.46 |
| 60ml | $ 0.46 |
| Amyrcl (India) | |
| Amyrcl Amoxicillin 250 mg, Ambroxol30 mg SYR / 30ml (Candor) | |
| Amyrcl Amoxicillin 250 mg, Ambroxol30 mg. DRY-SYR / 30ml (Candor) | |
| 30ml (Candor) | |
| AMYRCL dry syr 30ml (Candor) | |
| Anabron (Brazil) | |
| Anacof (India) | |
| Anacof Ambroxol 15mg, Terbutaline1.25mg, Guaiphenesin 50mg, Menthol 2.5mg SYR / 100ml (Anabiosis) | $ 0.59 |
| ANACOF syr 100ml (Anabiosis) | $ 0.59 |
| Anavix (Greece) | |
| Ankisol (Japan) | |
| ANTITUS (Paraguay) | |
| ANTITUS SYRUP 1 bottle / 100 ML syrup each (Fytokem Formulations) | $ 0.32 |
| Antitusivo (Argentina) | |
See 3105 substitutes for Amsiv | |
References
- PubChem. "ambroxol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "ambroxol". http://www.drugbank.ca/drugs/DB06742 (accessed September 17, 2018).
- MeSH. "Expectorants". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
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Information checked by Dr. Sachin Kumar, MD Pharmacology
