Bzon Uses

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What is Bzon?

Bzon sodium phosphate and Bzon acetate combination injection provides relief for inflamed areas of the body. It is used to treat a number of different conditions, such as inflammation (swelling), severe allergies, adrenal problems, arthritis, lung or breathing problems, blood or bone marrow problems, eye or vision problems, lupus, serious skin conditions, kidney problems, ulcerative colitis, and flare-ups of multiple sclerosis. Bzon sodium phosphate and Bzon acetate combination is a corticosteroid (cortisone-like medicine or steroid). It works on the immune system to help relieve swelling, redness, itching, and allergic reactions.

Bzon sodium phosphate and Bzon acetate is to be given only by or under the direct supervision of your doctor.

Bzon indications

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Bzon Suspension is indicated for the treatment of acute and chronic corticosteroid-responsive disorders. Corticosteroid hormone therapy is an adjunct to, and not a replacement for conventional therapy.

Musculoskeletal and Soft Tissue Conditions: Rheumatoid arthritis, osteoarthritis, bursitis, ankylosing spondylitis, epicondylitis, radiculitis, coccydynia, sciatica, lumbago, torticollis, ganglion cyst, exostasis and fasciitis.

Allergic Conditions: Chronic bronchial asthma (including adjunctive therapy for status asthmaticus), hay fever, angioneurotic edema, allergic bronchitis, seasonal or perennial allergic rhinitis, drug reactions, serum sickness and insect bites.

Dermatologic Conditions: Atopic dermatitis (nummular eczema), neurodermatitis (circumscribed lichen simplex), contact dermatitis, severe solar dermatitis, urticaria, hypertrophic lichen planus, necrobiosis lipoidica diabeticorum, alopecia areata, discoid lupus erythematosus, psoriasis, keloids, pemphigus, dermatitis herpetiformis and cystic acne.

Collagen Diseases: Disseminated lupus erythematosus, scleroderma, dermatomyositis, periarteritis nodosa.

Neoplastic Diseases: Palliative management of leukemias and lymphomas in adults; acute leukemia of childhood.

Other Conditions: Adrenogenital syndrome, ulcerative colitis, regional ileitis, sprue, podiatric conditions (bursitis under heloma durum, hallux rigidus, digiti quinti varus), affections requiring subconjunctival injection, corticosteroid-responsive blood dyscrasias, nephritis and nephrotic syndrome.

Primary or secondary adrenocortical insufficiency may be treated with Bzon Suspension but should be supplemented with mineralocorticosteroids, if applicable.

Bzon Suspension is recommended for intramuscular injection in conditions responsive to systemic corticosteroids; injection directly into the affected soft tissues where indicated; intra-articular and periarticular injection in arthritides; intralesional injection in various dermatologic conditions; and local injection in certain inflammatory and cystic disorders of the foot.

How should I use Bzon?

Use Bzon solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Bzon solution.

Uses of Bzon in details

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Bzon is used to treat allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, and bronchial asthma

Topical preparations of Bzon are used to treat skin problems like eczema (a type of itchy skin rash), atopic dermatitis (inflammation of skin) and psoriasis of the scalp, hands and feet.

Bzon description

Each gram of Bzon (Bzon*) Cream* contains: 640 mcg Bzon dipropionate (equivalent to 500 mcg Bzon).

Each gram of Bzon (Bzon*) Ointment* contains: 640 mcg Bzon dipropionate (equivalent to 500 mcg Bzon).

Bzon (Bzon*) Cream and Ointment contain Bzon dipropionate, a synthetic corticosteroid with anti-inflammatory activity to be administered topically.

Bzon dipropionate is a white to creamy white odorless crystalline powder insoluble in water; freely soluble in acetone and in chloroform; sparingly soluble in alcohol. It has a molecular weight of 504.16 and the empirical formula C28H37FO7; a chemical name of 9-fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione,17,21-dipropionate.

Bzon dosage

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Bzon Dosage

Generic name: Bzon dipropionate 0.5mg in 1g

Dosage form: ointment

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The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Apply a thin film of Bzon Ointment to the affected skin areas once or twice daily.

Therapy should be discontinued when control is achieved. If no improvement is seen within 2 weeks, reassessment of diagnosis may be necessary. Bzon Ointment is a super-high-potency topical corticosteroid. Treatment with Bzon Ointment should not exceed 50 g per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis.

Bzon Ointment should not be used with occlusive dressings unless directed by a physician.

Bzon Ointment is for topical use only. It is not for oral, ophthalmic, or intravaginal use.

Avoid use on the face, groin, or axillae, or if skin atrophy is present at the treatment site.

More about Bzon (Bzon topical)

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Other formulations

Related treatment guides

Bzon interactions

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What other drugs will affect Bzon?

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Concurrent use of phenobarbital, phenytoin, rifampin or ephedrine may enhance the metabolism of corticosteroids, reducing their therapeutic effects.

Patients receiving both a corticosteroid and an estrogen should be observed for excessive corticosteroid effects.

Concurrent use of corticosteroids with potassium-depleting diuretics may enhance hypokalemia. Concurrent use of corticosteroids with cardiac glycosides may enhance the possibility of arrhythmias or digitalis toxicity associated with hypokalemia. Corticosteroids may enhance the potassium depletion caused by amphotericin B. In all patients taking any of these drug therapy combinations, serum electrolyte determinations, particularly potassium levels, should be monitored closely.

Concurrent use of corticosteroids with coumarin-type anticoagulants may increase or decrease the anticoagulant effects, possibly requiring adjustment in dosage.

Combined effects of nonsteroidal anti-inflammatory drugs or alcohol with glucocorticosteroids may result in an increased occurrence or increased severity of gastrointestinal ulceration.

Corticosteroids may decrease blood salicylate concentrations. Acetylsalicylic acid should be used cautiously in conjunction with corticosteroids in hypoprothrombinemia.

Dosage adjustments of an antidiabetic drug may be necessary when corticosteroids are given to diabetics.

Concomitant glucocorticosteroid therapy may inhibit the response to somatotropin. Doses of Bzon in excess of 300-450 mcg (0.3-0.45 mg)/m2 of body surface per day should be avoided during administration of somatotropin.

Laboratory Tests: Corticosteroids may affect the nitro-blue tetrazolium test for bacterial infection and produce false-negative results.

Bzon side effects

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What are the possible side effects of Bzon?

Applies to Bzon topical: topical application cream, topical application foam, topical application gel/jelly, topical application lotion, topical application ointment

Other dosage forms:

In addition to its needed effects, some unwanted effects may be caused by Bzon topical (the active ingredient contained in Bzon). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking Bzon topical:

More common:

Less common: Incidence not known:

Minor Side Effects

Some of the side effects that can occur with Bzon topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:

Incidence not known:

Bzon contraindications

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What is the most important information I should know about Bzon?

You should not use this medication if you are allergic to Bzon, or if you have a fungal infection anywhere in your body.

Before taking Bzon, tell your doctor about all of your medical conditions, and about all other medicines you are using. There are many other diseases that can be affected by steroid use, and many other medicines that can interact with steroids.

Your steroid medication needs may change if you have any unusual stress such as a serious illness, fever or infection, or if you have surgery or a medical emergency. Tell your doctor about any such situation that affects you during treatment.

Steroid medication can weaken your immune system, making it easier for you to get an infection or worsening an infection you already have or have recently had. Tell your doctor about any illness or infection you have had within the past several weeks.

Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroid medication.

Do not receive a "live" vaccine while you are taking Bzon. Vaccines may not work as well while you are taking a steroid.

Do not stop using Bzon suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication.

Carry an ID card or wear a medical alert bracelet stating that you are taking a steroid, in case of emergency.



Active ingredient matches for Bzon:

Betamethasone


Unit description / dosage (Manufacturer)Price, USD
BZON 0.5 MG TABLET 1 strip / 10 tablets each (Unison Pharmaceuticals Pvt Ltd)$ 0.05
BZON FORTE 1 MG TABLET 1 strip / 10 tablets each (Unison Pharmaceuticals Pvt Ltd)$ 0.06
Bzon 0.5mg Tablet (Unison Pharmaceuticals Pvt Ltd)$ 0.00
Bzon 1mg Tablet (Unison Pharmaceuticals Pvt Ltd)$ 0.01

List of Bzon substitutes (brand and generic names):

Butenaskin BM Skin 15 gm Cream (Elder Pharmaceuticals Pvt Ltd)$ 0.66
Camnovate 0.1 % x 15 g x 1's (Camden)
Camnovate 0.1 % x 450 g x 1's (Camden)
Carebet S Skin 50 ml Lotion (Sure Care Pharma (P) Ltd.)$ 1.45
Catrisol 0.5 mg Tablet (Raddison Health Care Pvt Ltd)$ 0.00
Injectable; Injection; Betamethasone 4 mg / ml (Ifet)
Solution; Oral; Betamethasone 0.05% (Ifet)
Tablet, Dispersible; Oral; Betamethasone 2 mg (Ifet)
Celestene 4 mg/1 mL x 25 tube 1 mL (Ifet)
Tablets, Dispersible; Oral; Betamethasone 2 mg (Ifet)
Injectable; Injection; Betamethasone 4 mg / ml (Schering-plough)
Solution; Oral; Betamethasone 0.05% (Schering-plough)
Tablet, Dispersible; Oral; Betamethasone 2 mg (Schering-plough)
Celestene 4 mg/1 mL x 25 tube 1 mL (Schering-plough)
Tablets, Dispersible; Oral; Betamethasone 2 mg (Schering-plough)
Injectable; Injection; Betamethasone Acetate 3 mg; Betamethasone Sodium Phosphate 3 mg / ml
Injectable; Injection; Betamethasone Acetate 3 mg; Betamethasone Sodium Phosphate 3 mg / ml (Schering-plough)
Cream; Topical; Betamethasone Valerate 0.05%
Cream; Topical; Betamethasone Valerate 0.05%
Ointment; Topical; Betamethasone Valerate 0.05%

References

  1. DailyMed. "BETAMETHASONE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "betamethasone". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "betamethasone". http://www.drugbank.ca/drugs/DB00443 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Bzon are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Bzon. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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1 consumer reported age

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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