What happens if I overdose Bzon?
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local, or emergency room immediately.
Proper storage of Bzon solution:
Store Bzon solution at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Bzon solution out of the reach of children and away from pets.
Overdose of Bzon in details
Symptoms: Excessive or prolonged use of topical corticosteroids can suppress pituitary-adrenal function, resulting in secondary adrenal insufficiency and produce manifestations of hypercorticism, including Cushing's disease.
A single overdose of gentamicin would not be expected to produce symptoms. Excessive or prolonged use of topical antibiotics may lead to overgrowth of lesions by non-susceptible organisms.
Systemically, tolnaftate is pharmacologically inactive.
Clioquinol rarely produces iodism.
Treatment: Appropriate symptomatic treatment is indicated. Acute hypercorticoid symptoms are usually reversible. Treat electrolyte imbalance, if necessary. In case of chronic toxicity, slow withdrawal of corticosteroids is advised.
If overgrowth by non-susceptible organisms occurs, stop treatment with Bzon, Gentamicin, Tolnaftate, Clioquinol (Bzon) Cream and institute appropriate therapy.
What should I avoid while taking Bzon?
Avoid getting this medicine in your eyes. If contact does occur, rinse with water. Do not use Bzon topical on broken or infected skin. Also avoid using this medicine in open wounds.
Avoid applying Bzon topical to the skin of your face, underarms, or groin area without your doctor's instruction.
Do not use Bzon topical to treat any condition that has not been checked by your doctor.
Bzon warnings
Some medical conditions may interact with Bzon Valerate Cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have thinning of the skin, a skin infection, tuberculosis (TB), chickenpox, shingles, measles, or a positive TB skin test, or have recently been vaccinated
Some MEDICINES MAY INTERACT with Bzon Valerate Cream. Because little, if any, of Bzon Valerate Cream is absorbed into the blood, the risk of it interacting with another medicine is low.
Ask your health care provider if Bzon Valerate Cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Avoid long-term use, especially near the eyes, on the face, on the genital and rectal areas, and in skin folds.
Bzon Valerate Cream is for external use only. Avoid contact with eyes or eyelids. If you get Bzon Valerate Cream in your eyes, immediately flush with cool tap water.
Do not use Bzon Valerate Cream for other skin conditions at a later time.
If Bzon Valerate Cream was prescribed to treat the diaper area of a child, avoid using tight-fitting diapers or plastic pants.
Bzon Valerate Cream should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Bzon Valerate Cream while you are pregnant. It is not known if Bzon Valerate Cream is found in breast milk. If you are or will be breast-feeding while you use Bzon Valerate Cream, check with your doctor. Discuss any possible risks to your baby.
What should I discuss with my healthcare provider before taking Bzon?
For all uses of ReadySharp Bzon (Bzon (systemic)):
- If you have an allergy to Bzon or any other part of ReadySharp Bzon (Bzon (systemic)).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have a herpes infection of the eye.
- If you have any of these health problems: A fungal infection or malaria infection in the brain.
Injection (if given in the muscle):
- If you have idiopathic thrombocytopenic purpura (ITP).
This is not a list of all drugs or health problems that interact with ReadySharp Bzon (Bzon (systemic)).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take ReadySharp Bzon (Bzon (systemic)) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
Bzon precautions
If irritation or sensitization develops with the use of Bzon, Gentamicin, Tolnaftate, Clioquinol (Bzon) Cream, treatment should be discontinued and appropriate therapy instituted.
Any of the side effects that are reported following systemic use of corticosteroids, including adrenal suppression may also occur with topical corticosteroids, especially in infants and children.
Systemic absorption of Bzon, Gentamicin, Tolnaftate, Clioquinol (Bzon) Cream will be increased if extensive body surface areas are treated or if the occlusive technique is used. Suitable precautions should be taken under these conditions or when long-term use is anticipated, particularly in infants and children.
Cross-allergenicity among aminoglycosides has been demonstrated.
Systemic absorption of topically applied gentamicin may be increased if extensive body surface areas are treated, especially over prolonged time periods or in the presence of dermal disruption. In these cases, the undesirable effects which occur following systemic use of gentamicin may potentially occur. Cautious use is recommended under these conditions, particularly in infants and children.
Prolonged use of topical antibiotics occasionally may result in overgrowth of non-susceptible organisms. If this occurs or if irritation, sensitization or superinfection develops, treatment with Bzon, Gentamicin, Tolnaftate, Clioquinol (Bzon) Cream should be discontinued and appropriate therapy instituted. Slight staining of linens or clothing due to clioquinol may occur.
Bzon, Gentamicin, Tolnaftate, Clioquinol (Bzon) Cream is not for ophthalmic use.
Use in Children: Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced hypothalamic-pituitaryadrenal (HPA) axis suppression and to exogenous corticosteroids effects than mature patients because of greater absorption due to large skin surface area to body weight ratio.
HPA axis suppression, Cushing's syndrome, linear growth retardation, delayed weight gain, and intracranial hypertension have been reported in children receiving topical corticosteroids. Manifestations of adrenal suppression in children include low plasmacortisol levels and absence of response to ACTH stimulation. Manifestations of intracranial hypertension include a bulging fontanelle, headaches and bilateral papilledema.
What happens if I miss a dose of Bzon?
Call your doctor for instructions if you miss an appointment for your Bzon injection.
References
- DailyMed. "BETAMETHASONE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DrugBank. "betamethasone". http://www.drugbank.ca/drugs/DB00443 (accessed September 17, 2018).
- MeSH. "Anti-Asthmatic Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology
