What is Cipazole Forte?
Cipazole Forte is an antibiotic that fights bacteria.
Cipazole Forte is used in women to treat bacterial vaginal infections.
This medicine will not treat a fungal (yeast) infection.
Cipazole Forte may also be used for purposes not listed in this medication guide.
Cipazole Forte indications
Bacterial Vaginosis
Cipazole Forte is indicated for the treatment of bacterial vaginosis in adult women.
Usage
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cipazole Forte and other antibacterial drugs, Cipazole Forte should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
Uses of Cipazole Forte in details
Cipazole Forte is used to treat intestinal amoebiasis (infection of the intestinal), hepatic amoebiasis (infection of the liver), urethritis (infection of the urethra) and vaginitis (infection of the vagina) caused by Trichomonas vaginalis and giardiasis (parasitic infections).
Cipazole Forte description
Cipazole Forte (brand name Cipazole Forte,Sindose) is a nitroimidazole anti-infective. Effectiveness in the treatment of dientamoebiasis has been reported. It has also been tested against Atopobium vaginae.
Cipazole Forte dosage
Cipazole Forte Dosage
Generic name: Cipazole Forte 2g in 4.8g
Dosage form: oral granules
- Overview
- Side Effects
- Dosage
- Professional
- Interactions
- Pregnancy Warnings
- User Reviews
- Support Group Q & A
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Recommended Dosage
The recommended dosage of Cipazole Forte is a single 2-gram packet of granules taken once orally, without regard to the timing of meals.
Instructions for the Preparation and Administration of Cipazole Forte
- Open the Cipazole Forte packet by folding over the corner (marked by an arrow) and tearing across the top.
- Sprinkle the entire contents of the Cipazole Forte packet onto applesauce, yogurt or pudding. The granules will not dissolve. Consume all of the mixture within 30 minutes without chewing or crunching the granules. A glass of water may be taken after the administration of Cipazole Forte to aid in swallowing.
- The granules are not intended to be dissolved in any liquid.
More about Cipazole Forte (Cipazole Forte)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- 0 Reviews – Add your own review/rating
- Drug class: amebicides
Consumer resources
- Cipazole Forte
Professional resources
- Cipazole Forte (AHFS Monograph)
- Cipazole Forte (FDA)
Related treatment guides
- Bacterial Vaginitis
Cipazole Forte interactions
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What other drugs will affect Cipazole Forte?
BCG (Intravesical): Antibiotics may diminish the therapeutic effect of BCG (Intravesical). Avoid combination
BCG Vaccine (Immunization): Antibiotics may diminish the therapeutic effect of BCG Vaccine (Immunization). Monitor therapy
Cholera Vaccine: Antibiotics may diminish the therapeutic effect of Cholera Vaccine. Management: Avoid cholera vaccine in patients receiving systemic antibiotics, and within 14 days following the use of oral or parenteral antibiotics. Avoid combination
Lactobacillus and Estriol: Antibiotics may diminish the therapeutic effect of Lactobacillus and Estriol. Monitor therapy
Sodium Picosulfate: Antibiotics may diminish the therapeutic effect of Sodium Picosulfate. Management: Consider using an alternative product for bowel cleansing prior to a colonoscopy in patients who have recently used or are concurrently using an antibiotic. Consider therapy modification
Typhoid Vaccine: Antibiotics may diminish the therapeutic effect of Typhoid Vaccine. Only the live attenuated Ty21a strain is affected. Management: Vaccination with live attenuated typhoid vaccine (Ty21a) should be avoided in patients being treated with systemic antibacterial agents. Use of this vaccine should be postponed until at least 3 days after cessation of antibacterial agents. Consider therapy modification
Cipazole Forte side effects
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What are the possible side effects of Cipazole Forte?
Clinical Trials Experience
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.
The safety data described below reflect exposure to 589 patients, of whom 518 received a 2 g dose of Cipazole Forte. Cipazole Forte was evaluated in three clinical trials of patients diagnosed with bacterial vaginosis: two placebo-controlled trials (Trial 1 n=215, Trial 2 n=189) and one uncontrolled safety trial (Trial 3 n=321).
All patients received a single oral dose of study medication or placebo. Trial 1 evaluated a 1 g (this dose is not approved) dose (n=71) and a 2 g dose (n=72) of Cipazole Forte. Trial 2 evaluated a 2 g dose (n=125). The population was female, aged 15 to 54 years. Patients in the placebo- controlled trials were primarily Black or African American (54%) or Caucasian (41%).
There were no deaths in the trials. Two patients in Trial 3 discontinued due to vulvovaginal candidiasis in the Cipazole Forte-treated arm.
Most Common Adverse Reactions
Among 197 patients treated with a single 2 g dose of Cipazole Forte in the two placebo-controlled trials, Trial 1 and 2, adverse reactions were reported by approximately 29% of patients. Table 1 displays the most common adverse reactions (≥ 2 % in Cipazole Forte-treated patients) in these two trials.
| Adverse Reaction | Cipazole Forte N=197 n (%) | Placebo N=136 n (%) |
|---|---|---|
| Vulvo-vaginal candidiasis | 19 (9.6) | 4 (2.9) |
| Headache | 7 (3.6) | 2 (1.5) |
| Nausea | 7 (3.6) | 1 (0.7) |
| Diarrhea | 5 (2.5) | 1 (0.7) |
| Abdominal pain | 4 (2.0) | 2 (1.5) |
| Vulvovaginal pruritus | 4 (2.0) | 2 (1.5) |
Among the 321 patients in an uncontrolled trial, Trial 3, adverse reactions were reported in 30% of patients. Vulvovaginal candidiasis (8.4%), nausea (5.3%), vomiting (2.5%) and dysgeusia (3.4%) were the most common adverse reactions reported in this trial.
Postmarketing Experience
The following adverse reactions have been reported during use of other formulations of Cipazole Forte 2 g outside of the United States. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
Reported adverse reactions were nausea, dysgeusia, abdominal pain, headache, and vomiting.
Cipazole Forte contraindications
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What is the most important information I should know about Cipazole Forte?
Hypersensitivity
Cipazole Forte is contraindicated in patients who have shown hypersensitivity to Cipazole Forte, other ingredients of the formulation, or other nitroimidazole derivatives.
Active ingredient matches for Cipazole Forte:
Secnidazole in Egypt.
List of Cipazole Forte substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Canvir (Ecuador) | |
| Daksol 1 g (Venezuela) | |
| Daksol 500 mg (Venezuela) | |
| Daksol 750 mg (Venezuela) | |
| Dazoserc (Vietnam) | |
| Decnazol (Brazil) | |
| Deprozol (Brazil) | |
| Dysen Forte (Pakistan) | |
| Ecuzol (Ecuador) | |
| Enirobe (Pakistan) | |
| Entosec (India) | |
| ENTOSEC Capsule/ Tablet / 1 g / 2 units (Cipla (Protec)) | $ 0.39 |
| Entosec 1gm TAB / 2 (Cipla (Protec)) | $ 0.41 |
| 1 g x 2's (Cipla (Protec)) | $ 0.41 |
| ENTOSEC 1000MG TABLET 1 strip / 2 tablets each (Cipla (Protec)) | $ 0.40 |
| ENTOSEC 1G TABLET 1 strip / 2 tablets each (Cipla (Protec)) | $ 0.45 |
| ENTOSEC tab 1 g x 2's (Cipla (Protec)) | $ 0.41 |
| Entosec 1000mg Tablet (Cipla (Protec)) | $ 0.20 |
| Entosec 1g Tablet (Cipla (Protec)) | $ 0.23 |
| Esnidazol (Ecuador) | |
| Etisec (India) | |
| Etisec 1g SACHET / 25 (Novartis (Sandoz)) | $ 6.48 |
| Etisec 2g SACHET / 25 (Novartis (Sandoz)) | $ 12.05 |
| Etisec 500mg SACHET / 25 (Novartis (Sandoz)) | $ 5.12 |
| 1 g x 25's (Novartis (Sandoz)) | $ 6.48 |
| 2 g x 25's (Novartis (Sandoz)) | $ 12.05 |
| 500 mg x 25's (Novartis (Sandoz)) | $ 5.12 |
| ETISEC 1000MG POWDER 1 box / 1 GM powder each (Novartis (Sandoz)) | $ 0.20 |
| ETISEC 2000MG POWDER 1 box / 2 GM powder each (Novartis (Sandoz)) | $ 0.48 |
| ETISEC SACHET 1 packet / 1 GM sachet each (Novartis (Sandoz)) | $ 0.26 |
| Etisec 1000mg Powder (Novartis (Sandoz)) | $ 0.20 |
| Etisec 2000mg Powder (Novartis (Sandoz)) | $ 0.48 |
| Etisec NA Sachet (Novartis (Sandoz)) | $ 0.26 |
| Eurozole (Egypt) | |
| Fladazole (Tanzania) | |
| Flagena 500 | |
| Flagentyl (Argentina, Benin, Burkina Faso, Cameroon, Central African Republic, Chad, Congo, Cote D'ivoire, Gabon, Ghana, Guinea, Kenya, Madagascar, Mali, Mauritania, Mauritius, Niger, Nigeria, Oman, Portugal, Senegal, Togo, Turkey, Uganda, Vietnam, Zaire, Zimbabwe) | |
| Tablet, Oral; Secnidazole 500 mg (Sanofi Aventis) | |
| FLAGENTYL Capsule/ Tablet / 1 g / 2 units (Sanofi Aventis) | $ 0.42 |
| Flagentyl 500 mg x 4 Tablet (Sanofi Aventis) | |
| 1 g x 2's (Sanofi Aventis) | $ 0.42 |
| Flagentyl 500 mg x 48's (Sanofi Aventis) | $ 130.79 |
| Flagentyl 1g TAB / 2 (Sanofi Aventis) | $ 0.42 |
| Flagentyl 1000 mg Tablet (Sanofi Aventis) | $ 0.21 |
| FLAGENTYL 1000 MG TABLET 1 strip / 2 tablets each (Sanofi Aventis) | $ 0.39 |
See 298 substitutes for Cipazole Forte | |
References
- DailyMed. "SECNIDAZOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "Secnidazole". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Secnidazole". http://www.drugbank.ca/drugs/DB12834 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Cipazole Forte are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Cipazole Forte. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yet1 consumer reported time for results
To what extent do I have to use Cipazole Forte before I begin to see changes in my health conditions?As part of the reports released by ndrugs.com website users, it takes > 3 month and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Cipazole Forte. To get the time effectiveness of using Cipazole Forte drug by other patients, please click here.
| Users | % | ||
|---|---|---|---|
| > 3 month | 1 | 100.0% | |
4 consumers reported age
| Users | % | ||
|---|---|---|---|
| 30-45 | 2 | 50.0% | |
| 16-29 | 2 | 50.0% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
