Disflatyl Uses

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Disflatyl indications

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Peptic ulcer & gastric hyperacidity. Disflatyl Gastric hypermotility, spastic & irritable colon, flatulent dyspepsia, gastritis, heartburn, duodenitis, esophagitis, hiatus hernia, post-op abdominal pains, colic in childn.

Uses of Disflatyl in details

This product is used to relieve symptoms of extra gas such as belching, bloating, and feelings of pressure/discomfort in the stomach/gut. Disflatyl helps break up gas bubbles in the gut.

How to use Disflatyl

Take this product by mouth, usually after meals and at bedtime or as directed by your doctor. Swallow the capsules whole. Do not crush or chew the capsules. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

If you are self-treating with Disflatyl, the usual maximum amount for adults is 500 milligrams daily.

If your condition persists or worsens, or if you think you may have a serious medical problem, seek immediate medical attention.

Disflatyl description

A dopamine D2 antagonist that is used as an antiemetic.

Disflatyl dosage

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Oral

Flatulence

Adult: 100-250 mg 3-4 times daily as required. May be given with an antacid.

Oral

Infant colic

Child: Infant: 20-40 mg to be given with feeds.

Disflatyl interactions

Before taking metoclopramide, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by metoclopramide.

Tell your doctor about all other medications you use, especially:

acetaminophen (Tylenol);

cyclosporine (Gengraf, Neoral, Sandimmune);

digoxin (digitalis, Lanoxin);

glycopyrrolate (Robinul);

levodopa (Larodopa, Atamet, Parcopa, Sinemet);

mepenzolate (Cantil);

tetracycline (Brodspec, Panmycin, Robitet, Sumycin, Tetracap, and others);

atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);

bladder or urinary medications such as darifenacin (Enablex), tolterodine (Detrol), or solifenacin (Vesicare);

bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva);

irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin), or propantheline (Pro-Banthine);

an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate); or

medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (Clozaril, FazaClo), haloperidol (Haldol), olanzapine (Zyprexa, Symbyax), prochlorperazine (Compazine), risperidone (Risperdal), thiothixene (Navane), and others.

Disflatyl side effects

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Get emergency medical help if you have any of these signs of an allergic reaction to metoclopramide: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using metoclopramide and call your doctor at once if you have any of these serious side effects:

tremors, or restless muscle movements in your eyes, tongue, jaw, or neck;

mask-like appearance of the face;

very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out;

depressed mood, thoughts of suicide or hurting yourself;

hallucinations, anxiety, agitation, jittery feeling, trouble staying still;

swelling, fluid retention;

jaundice (yellowing of your skin or eyes); or

seizure (convulsions).

Less serious metoclopramide side effects may include:

feeling restless, drowsy, tired, or dizzy;

headache, sleep problems (insomnia);

nausea, vomiting, diarrhea;

breast tenderness or swelling;

changes in your menstrual periods; or

urinating more than usual.

Disflatyl contraindications

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Disflatyl should not be used whenever stimulation of gastrointestinal motility might be dangerous, e.g., in the presence of gastrointestinal hemorrhage, mechanical obstruction, or perforation.

Disflatyl is contraindicated in patients with pheochro-mocytoma because the drug may cause a hypertensive crisis, probably due to release of catecholamines from the tumor. Such hypertensive crises may be controlled by phen-tolamine.

Disflatyl is contraindicated in patients with known sensitivity or intolerance to the drug.

Disflatyl should not be used in epileptics or patients receiving other drugs which are likely to cause extrapyramidal reactions, since the frequency and severity of seizures or extrapyramidal reactions may be increased.

Active ingredient matches for Disflatyl:

Simeticone in Bahrain, Cyprus, Egypt, Finland, Georgia, Indonesia, Jordan, Kuwait, Lebanon, Oman, Philippines, Poland, Qatar, Russian Federation, Saudi Arabia, Singapore, Sudan, Switzerland, Thailand, United Arab Emirates, Yemen.

Activated dimethicone in Malaysia.

Dimethicone in Spain.

Dimethicone w/silicon dioxide in Singapore.

Dimethicone/Silicon Dioxide

Dimethylpolysiloxane in Indonesia.

Dimeticone in Indonesia, Malaysia.

Dimeticone/silicon dioxide in Hong Kong, Czech Republic, Indonesia.

Simethicone in Philippines.


Unit description / dosage (Manufacturer)Price, USD
Disflatyl 40 mg x 30's$ 3.88
Disflatyl 40 mg x 100's$ 15.94
Disflatyl 40 mg x 500's
Disflatyl Forte 80 mg x 500's
Disflatyl 40 mg/1 mL x 30 mL

List of Disflatyl substitutes (brand and generic names):

Drops; Oral; Simethicone 40 mg /ml
Tablet, Chewable; Oral; Simethicone 40 mg
Tablet; Oral; Dimethicone; Silicon Dioxide
Disilox MPS 200 ml Suspension (Stadmed Pvt Ltd)$ 0.01
Disilox MPS 250+250+50 Tablet (Stadmed Pvt Ltd)$ 0.01
DISOF DROPS 1 packet / 15 ML drop each (Clyde Biotech P Ltd)$ 0.48
Disof NA Drop (Clyde Biotech P Ltd)$ 0.48
Dom MPS 10+125 Tablet (Morepen Laboratories Ltd.)$ 0.03
DP 50MG/500MG TABLET 1 strip / 10 tablets each (Douglas)$ 0.23
DP 50 mg/500 mg Tablet (Douglas)$ 0.02
Cream; Topical; Dimethicone (Douglas)
Echicon 40 mg
Lotion; Topical; Dimethicone
Elzym 100's (Sankyo)
Entercon 40 mg
Enzovit Pancreatin, Bile Constituent, Hemicellulase, Simethicone TAB / 10 (Ethix HC)$ 0.72
10's (Ethix HC)$ 0.72
Enzovit Pancreatin , bile constituent, hemicellulase , simethicone. TAB / 10 (Ethix HC)$ 0.72
ENZOVIT tab 10's (Ethix HC)$ 0.72
Tablet; Oral; Amylase 2100 IU; Cellulasum 0.9 FIP; Dimethicone 20 mg; Glutamic Acid Hydrochloride 100 mg; Lipase 1200 IU; Methixene Hydrochloride 1 mg; Pepsini Pulvis 120 units; Protease 80 IU; Sodium Dehydrocholate 20 mg (Novartis consumer)
Tablet; Oral; Dimethicone 40 mg; Vitamin B5 / Calcium Pantothenate 50 mg (Valeant)
Suspension; Oral; Dimethicone 500 mg / 5 ml

References

  1. PubChem. "DIMETHICONE". https://pubchem.ncbi.nlm.nih.gov/sub... (accessed September 17, 2018).
  2. PubChem. "Simethicone". https://pubchem.ncbi.nlm.nih.gov/sub... (accessed September 17, 2018).
  3. PubChem. "Silicon". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Disflatyl are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Disflatyl. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

6 consumers reported useful

Was the Disflatyl drug useful in terms of decreasing the symptom or the disease?
According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
Users%
Not useful4
66.7%
Useful2
33.3%


5 consumers reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Disflatyl drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users%
Not expensive4
80.0%
Expensive1
20.0%


8 consumers reported time for results

To what extent do I have to use Disflatyl before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 3 days and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Disflatyl. To get the time effectiveness of using Disflatyl drug by other patients, please click here.
Users%
3 days2
25.0%
1 week2
25.0%
1 month1
12.5%
2 weeks1
12.5%
> 3 month1
12.5%
1 day1
12.5%


43 consumers reported age

Users%
30-4511
25.6%
> 6011
25.6%
46-606
14.0%
16-295
11.6%
1-54
9.3%
< 14
9.3%
6-152
4.7%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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