Doril Uses

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What is Doril?

Doril topical is used to treat many skin disorders, such as acne, dandruff, psoriasis, seborrheic dermatitis of the skin and scalp, calluses, corns, common warts, and plantar warts, depending on the dosage form and strength of the preparation.

Doril is available without a prescription. Some of these preparations are available only with your doctor's prescription.

Doril indications

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For Dermatologic Use: Doril 6% is a topical aid in the removal of excessive keratin in hyperkeratotic skin disorders including verrucae, and the various ichthyoses (vulgaris, sex-linked and lamellar), keratosis palmaris and plantaris keratosis pilaris, pityriasis rubra pilaris, and psoriasis (including body, scalp, palms and soles).

For Podiatric Use: Doril 6% is a topical aid in the removal of excessive keratin on dorsal and plantar hyperkeratotic lesions.

Topical preparations of 6% Doril have been reported to be useful adjunctive therapy for verrucae plantares.

How should I use Doril?

Use Doril shampoo as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Doril shampoo.

Uses of Doril in details

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This medication is used on the skin to treat common skin and foot (plantar) warts. Doril helps cause the wart to gradually peel off. This medication is also used to help remove corns and calluses. This product should not be used on the face or on moles, birthmarks, warts with hair growing from them, or genital/anal warts.

Doril is a keratolytic. It belongs to the same class of drugs as aspirin (salicylates). It works by increasing the amount of moisture in the skin and dissolving the substance that causes the skin cells to stick together. This makes it easier to shed the skin cells. Warts are caused by a virus. Doril does not affect the virus.

How to use Doril topical

Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

This medication is for use on the skin only. To avoid irritation, do not let this medication come into contact with your eyes, nose, mouth, groin, or any broken skin. If you do get the medication in those areas, flush the area with cool water for 15 minutes. Wash hands after use.

First, soak the corn, callus, or wart in warm water for about 5 minutes to soften the treatment area. Dry thoroughly. Your doctor may direct you to use a pumice stone, callus file, or emery board to carefully remove the top dead layers of skin after soaking and before applying the medication. This dead skin removal is only to help the medication work better. Do not try to rub the wart or callus off.

If you are using a liquid/gel, apply a few drops or a thin coat of the medication to cover the entire wart, callus, or corn using the applicator if provided. Be careful to apply it only to the affected area and not the surrounding skin. Let dry for 5 minutes. Depending on the brand used, you may need to apply the medication twice with each treatment. Check your product package and follow the directions carefully. You may cover the area loosely with a bandage. Repeat this procedure 1 to 2 times daily for up to 2 weeks for corns and calluses and 12 weeks for warts or as directed by your doctor.

If you are using a medicated pad or bandage, you may need to cut the pad so that it covers the treatment area completely but does not touch the surrounding skin. Peel off the protective covering and place the patch/bandage over the area. Leave in place according to package directions. Remove and place a new patch/bandage as directed (usually every 8 to 48 hours depending on brand). Repeat this procedure for up to 2 weeks for corns and calluses and 12 weeks for warts.

Dosage is based on your medical condition, product type/brand, and response to treatment. Do not use large amounts, apply this medication more often, or use it for a longer period than directed. Your condition will not clear faster, but the chance for side effects may be increased.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day.

If your condition persists or worsens, or if you think you may have a serious medical problem, seek immediate medical attention.

Doril description

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Each mL contains anthraquinone glycosides 50 mg, Doril 10 mg and alcohol 60%.

Doril dosage

Doril Dosage

Generic name: Doril 275mg in 1mL

Dosage form: topical solution

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Rx only

FOR TOPICAL USE ONLY.

NOT FOR OPHTHALMIC, ORAL OR INTRAVAGINAL USE.

DESCRIPTION

Doril is a topical preparation containing 27.5% Doril in a proprietary film-forming vehicle that comprises isopropyl alcohol, butyl acetate, polyvinyl butyral, isopropyl metacresol, trimethyl pentanyl diisobutyrate, phenic acid and acrylates copolymer. The pharmacologic activity of Doril is generally attributed to the keratolytic activity of Doril which is incorporated into a polyacrylic, film-forming virucidal vehicle designed to cover the wart without the need for a bandage. The structural formula of Doril is:

CLINICAL PHARMACOLOGY

Although the exact mode of action for Doril in the treatment of warts is unknown, its activity appears to be associated with its keratolytic action, which results in mechanical removal of epidermal cells infected with wart viruses.

The virucidal complex incorporated into Doril’s proprietary vehicle is designed to help reduce risk of reinfection at the wart site, as well as prevent viral contamination of the product under normal usage.

INDICATIONS AND USAGE

Doril is indicated for the topical treatment and removal of common warts and plantar warts.

CONTRAINDICATIONS

Patients with diabetes or impaired blood circulation should not use Doril. Doril also should not be used on moles, birthmarks, and unusual warts with hair growing from them, or warts on the face.

PRECAUTIONS

Doril is for external use only. Do not permit Doril to contact eyes or mucous membranes. If contact with eyes or mucous membranes occurs, immediately flush with water for 15 minutes. Doril should not be allowed to contact normal skin surrounding wart, since localized irritation may occur. Treatment should be discontinued if excessive irritation occurs. Doril is flammable. Keep away from fire or flame. Keep bottle tightly capped when not in use.

ADVERSE REACTIONS

A localized irritant reaction may occur if Doril is applied to the normal skin surrounding the wart. Any irritation may normally be controlled by temporarily discontinuing use and by applying the medication only to the wart site when treatment is resumed.

DOSAGE AND ADMINISTRATION

Prior to applying Doril, soak wart in warm water for five minutes. Remove any loosened tissue by gently rubbing with a brush, wash cloth, or emery board. Dry wart site thoroughly. Using the brush applicator supplied, apply Doril twice to entire wart surface, allowing the first application to dry before applying the second. Continue treatment once or twice a day as directed by physician. Be careful not to apply to surrounding skin.

Clinically visible improvement will normally occur during the first or second week of therapy. Maximum resolution may be expected after four to six weeks of Doril use.

HOW SUPPLIED

Doril is supplied in 10ml amber bottles with a brush applicator (NDC 42783-312-10).

Store at controlled room temperature, 15° to 30°C (59° to 86°F).

Manufactured for:

Elorac, Inc.

Vernon Hills, IL 60061

U.S. Patent Pending

Revised 06/2011

221619

More about Doril (Doril topical)

Consumer resources

Professional resources

Related treatment guides

Doril interactions

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Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to Doril or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Young children may be at increased risk of unwanted effects because of increased absorption of Doril through the skin. Also, young children may be more likely to get skin irritation from Doril. Doril should not be applied to large areas of the body, used for long periods of time, or used under occlusive dressing (air-tight covering, such as kitchen plastic wrap) in infants and children. Doril should not be used in children younger than 2 years of age.

Geriatric

Elderly people are more likely to have age-related blood vessel disease. This may increase the chance of problems during treatment with Doril.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Doril side effects

See also:
What are the possible side effects of Doril?

Less common or rare

Skin irritation not present before use of Doril (moderate or severe)

Frequency not known

Dryness and peeling of skin

flushing

redness of skin

unusually warm skin

Symptoms of Doril poisoning

Confusion

diarrhea

dizziness

fast or deep breathing

headache (severe or continuing)

hearing loss

lightheadedness

nausea

rapid breathing

ringing or buzzing in ears (continuing)

severe drowsiness

stomach pain

vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

-Skin irritation not present before use of Doril (mild) -stinging

Doril contraindications

See also:
What is the most important information I should know about Doril?

Less common or rare

Skin irritation not present before use of Doril (moderate or severe)

Frequency not known

Dryness and peeling of skin

flushing

redness of skin

unusually warm skin

Symptoms of Doril poisoning

Confusion

diarrhea

dizziness

fast or deep breathing

headache (severe or continuing)

hearing loss

lightheadedness

nausea

rapid breathing

ringing or buzzing in ears (continuing)

severe drowsiness

stomach pain

vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

-Skin irritation not present before use of Doril (mild) -stinging



Active ingredient matches for Doril:

Salicylic Acid in Brazil.

Aspirin/caffeine in Brazil.


List of Doril substitutes (brand and generic names)

Sort by popularity
Unit description / dosage (Manufacturer)Price, USD
Liquid; Topical; Salicylic Acid 12.64%
Patch; Topical; Salicylic Acid 40%
Gel; Topical; Salicylic Acid 17%
Liquid; Topical; Salicylic Acid 17%
Patch; Topical; Salicylic Acid 40%
Patch; Topical; Salicylic Acid 40%
Patch; Topical; Salicylic Acid 40%
Patch; Topical; Salicylic Acid 40%
Plaster; Topical; Salicylic Acid 40%
Patch; Topical; Salicylic Acid 40%
Patch; Topical; Salicylic Acid 40%
Patch; Topical; Salicylic Acid 40%
Plaster; Topical; Salicylic Acid 40%
Patch; Topical; Salicylic Acid 40%
Patch; Topical; Salicylic Acid 40%
Patch; Topical; Salicylic Acid 40%
Patch; Topical; Salicylic Acid 40%

References

  1. DailyMed. "CAFFEINE; ERGOTAMINE TARTRATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "ASPIRIN; DIPYRIDAMOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. PubChem. "salicylic acid". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Doril are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Doril. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


Consumer reported price estimates

No survey data has been collected yet


1 consumer reported time for results

To what extent do I have to use Doril before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes > 3 month and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Doril. To get the time effectiveness of using Doril drug by other patients, please click here.
Users%
> 3 month1
100.0%


Consumer reported age

No survey data has been collected yet


Consumer reviews


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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