How do you administer this medicine?
Dosage of Dramenex in details
The dose of a drug and dosage of the drug are two different terminologies. Dose is defined as the quantity or amount of medicine given by the doctor or taken by the patient at a given period. Dosage is the regimen prescribed by the doctor about how many days and how many times per day the drug is to be taken in specified dose by the patient. The dose is expressed in mg for tablets or gm, micro gm sometimes, ml for syrups or drops for kids syrups. The dose is not fixed for a drug for all conditions, and it changes according to the condition or a disease. It also changes on the age of the patient.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Generic: 50 mg/mL (1 mL)
Dramamine: 50 mg
Driminate: 50 mg
Driminate: 50 mg [scored]
GoodSense Motion Sickness: 50 mg [scored]
Motion Sickness: 50 mg [DSC]
Generic: 50 mg [DSC]
Dramamine: 50 mg [contains aspartame, fd&c yellow #6 aluminum lake]
US labeling: Motion sickness, nausea/vomiting, or vertigo:
Oral: 50 to 100 mg every 4 to 6 hours (maximum: 400 mg/day)
IM, IV: 50 mg every 4 hours; maximum: 100 mg every 4 hours
Canadian labeling: Nausea/vomiting or vertigo:
Oral: 50 to 100 mg every 4 hours as necessary (maximum: 400 mg/day); Long acting formulation: 100 mg every 8 to 12 hours (maximum: 300 mg/day)
Rectal: 50 to 100 mg every 6 to 8 hours as necessary
Oral: 50 to 100 mg prior to procedure then 50 to 100 mg post-procedure; repeat as necessary (maximum: 400 mg/day)
IM, IV: 50 mg prior to treatment then 50 mg post-procedure; repeat as necessary (maximum: 400 mg/day)
IM, IV: 50 to 100 mg 30 to 60 minutes prior to treatment; 50 mg 1.5 and 3 hours after treatment. Repeat dose as necessary (maximum: 400 mg/day)
Rectal: 50 to 100 mg 30 to 60 minutes prior to treatment; repeat as necessary (maximum: 400 mg/day)
Nausea and vomiting of pregnancy (off-label use) (Arsenault 2002):
Oral, rectal: 50 to 100 mg every 4 to 6 hours; maximum dose: 200 mg/day (when taking four doxylamine/pyridoxine tablets per day) or 400 mg/day
IV: 50 mg every 4 to 6 hours
Avoid use (Beers Criteria [AGS 2019]).
Motion sickness, nausea/vomiting, or vertigo, prophylaxis:
Fixed dose: Administer initial dose 30 to 60 minutes before travel/activity
Children ≥2 to <6 years:
Oral: 12.5 to 25 mg every 6 to 8 hours; maximum daily dose: 75 mg/24 hours
Children ≥6 years to <12 years:
Oral: 25 to 50 mg every 6 to 8 hours; maximum daily dose: 150 mg/24 hours
Children ≥12 years and Adolescents:
Oral: 50 to 100 mg every 4 to 6 hours; maximum daily dose: 400 mg/24 hours
Weight-based dosing: Children 2 to 12 years:
Oral: Limited data available: 1 to 1.5 mg/kg/dose every 6 hours; maximum dose: 25 mg/dose. First dose should be administered 60 minutes prior to travel (CDC 2017).
Parenteral products: IM:
Weight-based dosing: Infants, Children, and Adolescents: IM: 1.25 mg/kg/dose 4 times daily; maximum daily dose: 300 mg/day
BSA-based dosing: Infants, Children, and Adolescents: IM: 37.5 mg/m/dose 4 times daily; maximum daily dose: 300 mg/day
Canadian labeling: Rectal suppository [Canadian product]:
Children 2 to ≤5 years: Rectal: 12.5 mg to 25 mg once; if more doses needed, contact health care provider
Children 6 to 7 years: Rectal: 12.5 to 25 mg every 8 to 12 hours as needed
Children 8 to 11 years: Rectal: 25 to 50 mg every 8 to 12 hours as needed
Children ≥12 years and Adolescents: Rectal: 50 mg every 8 to 12 hours as needed
Postoperative nausea and vomiting (PONV): Limited data available:
Prevention: Infants, Children, and Adolescents: IV: 0.5 mg/kg/dose; maximum dose: 25 mg/dose (Gan 2014)
Weight-directed: Infants, Children, and Adolescents: IV: 0.5 mg/kg/dose; maximum dose: 25 mg/dose; for treatment of PONV, use only if prophylaxis fails and Dramenex is from a different pharmacologic class than prophylactic drug (Gan 2014)
Fixed dose (Gravol prescribing information [Canada] 2016):
Children 6 to 7 years: IM, IV: 15 to 25 mg two or three times daily
Children 8 to 12 years: IM, IV: 25 to 50 mg two or three times daily
Children ≥12 years and Adolescents: IM, IV: 50 mg two or three times daily
What other drugs will affect Dramenex?
Dramenex may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine unless your doctor approves.
Drugs other than those listed here may also interact with Dramenex. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
Interactions are the effects that happen when the drug is taken along with the food or when taken with other medications. Suppose if you are taking a drug Dramenex, it may have interactions with specific foods and specific medications. It will not interact with all foods and medications. The interactions vary from drug to drug. You need to be aware of interactions of the medicine you take. Most medications may interact with alcohol, tobacco, so be cautious.
The absorption of oral medications may be decreased during the concurrent use of scopolamine because of decreased gastric motility and delayed gastric emptying.
Dramenex should be used with care in patients taking other drugs that are capable of causing CNS effects such as sedatives, tranquilizers, or alcohol. Special attention should be paid to potential interactions with drugs having anticholinergic properties; e.g., other belladonna alkaloids, antihistamines (including meclizine), tricyclic antidepressants, and muscle relaxants.
Laboratory Test Interactions
Dramenex will interfere with the gastric secretion test.
ReviewsThe results of a survey conducted on ndrugs.com for Dramenex are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Dramenex. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
3 consumers reported frequency of useHow frequently do I need to take Dramenex?
It was reported by ndrugs.com website users that Dramenex should ideally be taken Once in a day as the most common frequency of the Dramenex. You should you adhere strictly to the instructions and guidelines provided by your doctor on how frequently this Dramenex should be taken. Get another patient's view on how frequent the capsule should be used by clicking here.
8 consumers reported dosesWhat doses of Dramenex drug you have used?
The drug can be in various doses. Most anti-diabetic, anti-hypertensive drugs, pain killers, or antibiotics are in different low and high doses and prescribed by the doctors depending on the severity and demand of the condition suffered by the patient. In our reports, ndrugs.com website users used these doses of Dramenex drug in following percentages. Very few drugs come in a fixed dose or a single dose. Common conditions, like fever, have almost the same doses, e.g., [acetaminophen, 500mg] of drug used by the patient, even though it is available in various doses.
Information checked by Dr. Sachin Kumar, MD Pharmacology