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Dramenex Dosage |
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Applies to the following strength(s): 50 mg/mL; 50 mg; 12.5 mg/5 mL; 12.5 mg/4 mL
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
-IM: 50 mg every 4 hours injected intramuscularly as needed; Maximum Dose: 100 mg every 4 hours
-IV: 50 mg every 4 hours injected intravenously over a period of 2 minutes; Maximum Dose: 100 mg every 4 hours
-Oral: 50 to 100 mg orally every 4 to 6 hours; Maximum Dose: 400 mg in 24 hours
Comments:
-For IV administration: Each mL (50 mg) must be diluted in 10 mL of 0.9% sodium chloride injection.
-The first dose should be taken one-half to one hour before starting activity.
-The injectable form is indicated when the oral form is impractical.
Use: Prevention and treatment of nausea, vomiting, dizziness, or vertigo associated with motion sickness.
IM: 1.25 mg/kg OR 37.5 mg/m2 injected intramuscularly 4 times a day; Maximum Dose: 300 mg/day
-Age 2 to 5: 12.5 to 25 mg orally every 6 to 8 hours; Maximum Dose: 75 mg in 24 hours
-Age 6 to 11: 25 to 50 mg orally every 6 to 8 hours; Maximum Dose: 150 mg in 24 hours
-Age 12 and older: 50 to 100 mg orally every 4 to 6 hours; Maximum Dose: 400 mg in 24 hours
Comments:
-The first dose should be taken one-half to one hour before starting activity.
-The injectable form is indicated when the oral form is impractical.
Use: Prevention and treatment of nausea, vomiting, dizziness, or vertigo associated with motion sickness.
Data not available
Data not available
Do not use in patients younger than 2 years unless directed by a doctor.
Consult WARNINGS section for additional precautions.
Data not available
Administration Advice:
-The solution form should not be injected intra-arterially.
Storage Requirements:
-This drug should be protected from moisture and stored at 20 to 25 degrees Celsius (68 to 77 Fahrenheit).
General:
-Overdosage: Convulsions, coma, respiratory depression, and drowsiness may occur with overdosage. There is no specific antidote; the manufacturer product information should be consulted for drugs that may be used to treat overdosage effects.
-In mice, the oral LD50 is 203 mg/kg and the intraperitoneal LD50 is 149 mg/kg; the LD50 in rats is 1,320 mg/kg.
-There is no human data indicating this drug is a carcinogen or mutagen.
Patient Advice:
-Avoid alcoholic drinks, sedatives, and tranquilizers while taking this drug.
-This drug may cause side effects such as drowsiness and dizziness that can affect your ability to perform certain activities; avoid driving and potentially hazardous activities such as operating machinery until you know how this drug affects you.
-If overdosage occurs, get immediate medical help or contact a Poison Control Center right away.
Dramenex may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine unless your doctor approves.
Drugs other than those listed here may also interact with Dramenex. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
The absorption of oral medications may be decreased during the concurrent use of scopolamine because of decreased gastric motility and delayed gastric emptying.
Dramenex should be used with care in patients taking other drugs that are capable of causing CNS effects such as sedatives, tranquilizers, or alcohol. Special attention should be paid to potential interactions with drugs having anticholinergic properties; e.g., other belladonna alkaloids, antihistamines (including meclizine), tricyclic antidepressants, and muscle relaxants.
Dramenex will interfere with the gastric secretion test.
Users | % | ||
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Once in a day | 2 | 66.7% | |
4 times in a day | 1 | 33.3% |
Users | % | ||
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11-50mg | 7 | 87.5% | |
51-100mg | 1 | 12.5% |
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Information checked by Dr. Sachin Kumar, MD Pharmacology
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