Estel Uses

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Estel indications

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Allergic rhinitis or chronic idiopathic urticaria, seasonal allergic rhinitis. Inhibition of histamine-induced wheal & flare reactions of the skin due to allergens or medications.

Uses of Estel in details

Estel is used to treat allergic conditions.

Estel description

Estel (trade names Kestine, Evastin, Estel, Aleva) is a non-sedating H1 antihistamine. It does not penetrate the blood-brain barrier and thus allows an effective block of the H1 receptor in peripheral tissue without a central side effect, i.e not causing sedation or drowsiness.

Estel dosage

Histamine-induced wheal & flare 10 mg/day. Pruritus 10 mg/day. Severe pruritus Initially, 20 mg/day. Reduce to 10 mg/day upon improvement of itching. Allergic rhinitis or chronic idiopathic urticaria 10 mg as a single daily dose. Seasonal allergic rhinitis 20 mg/day.

Estel interactions

Concomitant use of ketoconazole, itraconazole, clarithromycin or erythromycin may increase plasma levels of Estel and cause QTc interval prolongation.

Estel side effects

Nausea, Drowsiness, Abdominal pain, Dry mouth, Headache, Indigestion, Insomnia, Nose bleed, Nasal infection, Sinus inflammation, Sore throat, Weakness

Estel contraindications

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Allergic conditions including rhinitis and pruritic skin disorders

Active ingredient matches for Estel:

Ebastine in South Korea.


List of Estel substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
EST tab 10's (Jpee (SHB))$ 0.90
Estimin 5 mg
ESTINA 0.5 MG EYE DROP 1 packet / 5 ML eye drop each (Entod Pharmaceuticals Ltd)$ 0.90
Estina 0.5mg Eye Drop (Entod Pharmaceuticals Ltd)$ 0.90
Solution; Oral; Ebastine 5 mg / 5 ml (Almirall)
Tablet, Film-Coated; Oral; Ebastine 10 mg (Almirall)
Tablet, Film-Coated; Oral; Ebastine 20 mg (Almirall)
Wafer; Topical; Ebastine 20 mg
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Glubex-ZL Lycopene 6% 200 mcg, vitamin A2500 IU, vitamin E acetate 10IU, vitamin C 50 mg, zincsulphate monohydrate 27.45 mg, selenium dioxide 70 mcg, carbohydrate 0.053 g, Totalfat 0.076 g, protein 0.034 g. SYR / 200ml (Vensat)
GLUBEX-ZL syr 200ml (Vensat)
Hestin 6 mg Tablet (Articon Labs)$ 0.19
Hestin 3 mg Tablet (Articon Labs)$ 0.11
HESTIN 6MG TABLET 1 strip / 4 tablets each (Articon Labs)$ 1.43
Hestin 6mg Tablet (Articon Labs)$ 0.36
Tablet, Film-Coated; Oral; Ebastine 10 mg (Almirall)
Syrup; Oral; Ebastine 5 mg / 5 ml (Almirall Prodesfarma)
Tablet, Film-Coated; Oral; Ebastine 10 mg (Almirall Prodesfarma)
Tablet, Film-Coated; Oral; Ebastine 20 mg (Almirall Prodesfarma)
Kestine 10 mg x 10 Tablet (Almirall Prodesfarma)
Kestine 10 mg x 30's (Almirall Prodesfarma)
Kestine tab 10 mg 30's (Almirall Prodesfarma)
Powder; Oral; Ebastine 10 mg
Yesbat 20 mg Tablet (Nirix Derma)$ 0.08
Yesbat 10 mg Tablet (Nirix Derma)$ 0.05

References

  1. PubChem. "ebastine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Ebastine". http://www.drugbank.ca/drugs/DB11742 (accessed September 17, 2018).
  3. MeSH. "Histamine H1 Antagonists". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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