Fei Ke Tan Uses

• Fei Ke Tan indications
• Uses of Fei Ke Tan in details
• Fei Ke Tan description
• Fei Ke Tan dosage
• Fei Ke Tan interactions
• Fei Ke Tan side effects
• Fei Ke Tan contraindications

What is Fei Ke Tan?

Fei Ke Tan injection is used to prevent bronchospasm in patients 12 years of age and older with asthma, bronchitis, emphysema, and other lung diseases.

Fei Ke Tan belongs to the family of medicines known as bronchodilators. Bronchodilators are medicines that relax the muscles in the bronchial tubes (air passages) of the lungs. They relieve cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes.

Fei Ke Tan is available only with your doctor's prescription.

Fei Ke Tan indications

Oral

Acute bronchospasm

Adult: Initially, 2.5 mg or 3 mg tid, up to 5 mg tid as necessary. As modified-release tab: 5 mg or 7.5 mg bid.

Child: <12 yr Initially, 0.05 mg/kg/dose tid, increase gradually as required. Max: 5 mg/day; 12-15 yr 2.5 mg tid; >15 yr Same as adult dose.

Inhalation

Acute bronchospasm

Adult: As metered-dose powd inhaler: 250-500 mcg as required. Max: 2,000 mcg daily.

Parenteral

Severe bronchospasm

Adult: 250-500 mcg up to 4 times daily by SC, IM or IV inj, or by IV infusion as a soln containing 3-5 mcg/mL at a rate of 0.5-1 mL/min.

Child: 2-15 yr 0.01 mg/kg. Max: 0.3 mg/dose.

Reconstitution: Add 10 mL of Fei Ke Tan soln for inj to 40 mL of dextrose 5% if using a syringe pump or to 490 mL of dextrose 5% if syringe pump is not available.

Intravenous

Uncomplicated premature labour

Adult: To arrest labour between 22-37 wk of gestation: Initially, 5 mcg/min, w/ increments of 2.5 mcg/min at 20 min intervals until contractions stop. Max: 20 mcg/min. Continue for 1 hr after contractions have ceased, then decrease by 2.5 mcg/min every 20 min to lowest dose that maintains suppression. Max duration: 48 hr.

Reconstitution: Add 10 mL of Fei Ke Tan soln for inj to 40 mL of dextrose 5% if using a syringe pump or to 490 mL of dextrose 5% if syringe pump is not available.

Inhalation

Severe bronchospasm

Adult: As 1% nebuliser soln: 2.5-10 mg 2-4 times daily.

Child: <25 kg: 2-5 mg 2-4 times daily; ≥25 kg: 5 mg 2-4 times daily.

How should I use Fei Ke Tan?

Use Fei Ke Tan as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Fei Ke Tan is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Fei Ke Tan at home, a health care provider will teach you how to use it. Be sure you understand how to use Fei Ke Tan. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
• Do not use Fei Ke Tan if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
• Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
• If you miss a dose of Fei Ke Tan and are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Fei Ke Tan.

Uses of Fei Ke Tan in details

Use: Labeled Indications

Asthma/Bronchospasm: Prevention and reversal of bronchospasm in patients ≥12 years of age with asthma and reversible bronchospasm associated with bronchitis and emphysema

Off Label Uses

Extravasation management, sympathomimetic vasoconstrictors

Data from a limited number of patients suggests that Fei Ke Tan may be beneficial for the management of extravasation of sympathomimetic vasoconstrictors.

Fei Ke Tan description

Fei Ke Tan turbuhaler is a breath-activated, multiple-dose powder inhaler free from propellant, lubricant, preservative, carrier substances or other additives.

Fei Ke Tan injection also contains the following inactive ingredients: Sodium chloride, HCl (for pH adjustment) and water for injections.

Fei Ke Tan sulphate is 2-(tert-butylamino)-1-(3,5-dihydroxyphenyl)ethanol sulphate.

Fei Ke Tan dosage

Tablet: Adults: Usual Dose: 1-2 tablets. Children 12-15 years: 1 tablet. All doses to be taken 2-3 times daily.

To be administered at approximately 6-hr intervals. In most patients, the optimum single dose is 2 tablets. In patients unusually sensitive to sympathomimetic amines, initiate treatment with 1 tablet 3 times a day. If adequate bronchodilation is not obtained, the dose may be increased to 2 tablets.

Syrup: Adults and Children >15 years: 10-15 mL (2-3 tsp). Children 7-15 years: 5-10 mL (1-2 tsp); 3-7 years: 2.5-5 mL (½-1 tsp); <3 years: Not recommended. All doses to be taken 3 times a day.

Nebulizing Solution: Fei Ke Tan nebulizing solution is used with dilution.

Inhale 1 mL of solution containing Fei Ke Tan sulfate 2.5 mg every 6 hrs (or 4 times in 24-hr period).

If the entire dose is not inhaled at 1 occasion, the solution is stable for 24 hrs in the reservoir of the nebulizer.

Note: The patient's inhalation technique should be checked regularly and the optimal dose of Fei Ke Tan should be adjusted for each nebulizer. If the effect of the inhalation is reduced, the patient should seek medical care.

Nonselective blocking agents may partly or totally inhibit the effect of β-stimulants.

Directions for Use: 1. Pipette 1 mL of Fei Ke Tan nebulizing solution from the bottle by using a calibrated medicine dropper provided in the pack, equivalent to Fei Ke Tan sulfate 2.5 mg.

2. Drop the solution into an electric nebulizer and dilute it with normal saline solution 2 mL and start inhalation.

3. Repeat the same procedure every 6 hrs or 4 times in 24-hr period.

Fei Ke Tan interactions

See also:
What other drugs will affect Fei Ke Tan?

Drug Interactions

The concomitant use of Fei Ke Tan with other sympathomimetic agents is not recommended, since the combined effect on the cardiovascular system may be deleterious to the patient

Monoamine Oxidase Inhibitors or Tricyclic Antidepressants: Fei Ke Tan should be administered with extreme caution to patients being treated with monoamine oxidase inhibitors or tricyclic antidepressants, or within 2 weeks of discontinuation of such agents, since the action of Fei Ke Tan on the vascular system may be potentiated

Beta-Blockers Beta-adrenergic receptor blocking agents not only block the pulmonary effect of beta-agonists, such as Fei Ke Tan, but may produce severe bronchospasm in asthmatic patients. Therefore, patients with asthma should not normally be treated with beta-blockers. However, under certain circumstances, e.g., as prophylaxis after myocardial infarction, there may be no acceptable alternatives to the use of beta-adrenergic blocking agents in patients with asthma. In this setting, cardioselective beta-blockers could be considered, although they should be administered with caution

Diuretics The ECG changes and/or hypokalemia that may result from the administration of nonpotassium-sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. Although the clinical significance of these effects is not known, caution is advised in the coadministration of beta-agonists with nonpotassium-sparing diuretics.

Fei Ke Tan side effects

See also:
What are the possible side effects of Fei Ke Tan?

Applies to Fei Ke Tan: oral elixir, oral tablet

Other dosage forms:

• subcutaneous solution

In addition to its needed effects, some unwanted effects may be caused by Fei Ke Tan (the active ingredient contained in Fei Ke Tan). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking Fei Ke Tan:

More common:

• Shakiness in the legs, arms, hands, or feet
• trembling or shaking of the hands or feet

Less common:

• Extra heartbeat
• feeling faint, dizzy, or lightheadedness
• feeling of warmth or heat
• flushing or redness of the skin, especially on the face and neck
• headache
• sweating

Rare

• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• excessive muscle tone
• muscle stiffness
• muscle tension or tightness

If any of the following symptoms of overdose occur while taking Fei Ke Tan, get emergency help immediately:

Symptoms of overdose:

• Arm, back, or jaw pain
• blurred vision
• chest pain or discomfort
• chest tightness or heaviness
• confusion
• convulsions
• decreased urine
• dizziness
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• dry mouth
• fainting
• fast, pounding, or irregular heartbeat or pulse
• general feeling of discomfort or illness
• increased thirst
• loss of appetite
• mood changes
• muscle pain or cramps
• nausea or vomiting
• nervousness
• numbness or tingling in the hands, feet, or lips
• pounding in the ears
• seizures
• shortness of breath
• sleeplessness
• slow or fast heartbeat
• trouble sleeping
• unable to sleep
• unusual tiredness or weakness

Minor Side Effects

Some of the side effects that can occur with Fei Ke Tan may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:

• Sleepiness or unusual drowsiness

Less common:

• Anxiety
• lack or loss of strength

Rare

• Fever
• rash
• redness, soreness, or itching skin
• seeing, hearing, or feeling things that are not there
• sores, welting, or blisters

Fei Ke Tan contraindications

See also:
What is the most important information I should know about Fei Ke Tan?

1.

Prolonged Tocolysis

Fei Ke Tan sulfate has not been approved for and should not be used for prolonged tocolysis (beyond 48-72 hours). In particular, Fei Ke Tan sulfate should not be used for maintenance tocolysis in the outpatient or home setting.

2.

Hypersensitivity

Fei Ke Tan sulfate injection is contraindicated in patients known to be hypersensitive to sympathomimetic amines or any component of this drug product.

Active ingredient matches for Fei Ke Tan:

Terbutaline in China.

List of Fei Ke Tan substitutes (brand and generic names)	Sort by popularity
Unit description / dosage (Manufacturer)	Price, USD
Etoxin- B EXP
Etoxin- B EXP Terbutaline Sulphate 2mg, Bromhexine HCI 4mg, Guiaphenesin 100mg, Menthol1mg/10mL LIQD / 100ml	$ 0.38
Forasma (Indonesia, Taiwan)
Forasma 2.5 mg x 5 x 10's (Guardian)	$ 4.65
Forasma 1.5 mg/5 mL x 60 mL x 1's (Guardian)	$ 2.17
Forasma 1, 000's (Guardian)
Forasma 60 mL (Guardian)
Forasma 3.8 L (Guardian)
Forasma 40 mcg x 1000's (Guardian)
Framagon (Thailand)
Framagon 2.5 mg x 50 x 10's
Framagon 2.5 mg x 1000's
Geriresp
Geriresp 100 ml Expectorant (Alembic Chemical Works Co Ltd)	$ 0.02
GERIRESP 50MG/1.5MG/15MG SYRUP 1 bottle / 100 ML syrup each (Alembic Chemical Works Co Ltd)	$ 0.49
Geriresp Syrup (Alembic Chemical Works Co Ltd)	$ 0.49
Glin (Taiwan)
Glin 2.5 mg x 1000's
Gredex-TM (India)
Gredex-TM Terbutaline sulphate 1.25 mg, guaiphenesin 50 mg, bromhexinehydrochloride 4 mg, menthol2.5 mg. SYR / 100ml (Green Lab)	$ 0.60
GREDEX-TM syr 100ml (Green Lab)	$ 0.60
Grilinctus- BM
Grilinctus- BM Terbutaline 2.5mg, BromhexineHCI 8mg TAB / 10	$ 0.09
Grilinctus- BM Terbutaline 2.5mg, BromhexineHCI 8mg/5mL SYR / 100ml	$ 0.42
Grilinctus- BM Terbutaline 1.5mg, BromhexineHCI 4mg/5ml P- SYR / 30ml	$ 0.19
H CODEX Syrup
H CODEX Syrup (Health Guard (India) Pvt. Ltd.)	$ 0.01
Hui Bang (China)
KOFAREST-SF (India)
100ml (Centaur (Samruddhi))	$ 0.72
Kofarest-SF Terbutaline 1.25 mg, Ambroxol15 mg, Guaiphenesin 50 mg/5mL. SYR / 100ml (Centaur (Samruddhi))	$ 0.72
KOFAREST-SF syr 100ml (Centaur (Samruddhi))	$ 0.72
Kofarest-SF Terbutaline 1.25 mg, Ambroxol15 mg, Guaiphenesin 50 mg/5mL. SYR / 100ml (Centaur (Samruddhi))	$ 0.72
Kufgen X
Kufgen X 100 ml Syrup (Genesis Biotech Inc.)	$ 0.03
Lafayette Terbutaline Sulfate (Philippines)
Lanterbine (Hong Kong)
Lasmalin (Indonesia)
Lasmalin 2.5 mg x 100's (Lapi)	$ 8.68
Lasmalin 1.5 mg/5 mL x 100 mL x 1's (Lapi)	$ 1.98
Libitus Plus (India)
Libitus Plus TerbutalineSulphate1.25mg, BromhexineHCl4mg, Guaiphenesin50mg SYR / 60ml (Leben Labs)	$ 0.26
Libitus Plus TerbutalineSulphate1.25mg, BromhexineHCl4mg, Guaiphenesin50mg SYR / 100ml (Leben Labs)	$ 0.38
Libitus Plus Terbutaline sulphate 1.25 mg, Bromhexine hydrochloride 4 mg, Guaiphenesin 50 mg. SYR / 100ml (Leben Labs)	$ 0.38
Libitus Plus Terbutaline sulphate 1.25 mg, Bromhexine hydrochloride 4 mg, Guaiphenesin 50 mg. SYR / 60ml (Leben Labs)	$ 0.26
100ml (Leben Labs)	$ 0.38
60ml (Leben Labs)	$ 0.26
Libitus Plus TerbutalineSulphate 1.25mg, BromhexineHCl 4mg, Guaiphenesin 50mg SYR / 60ml (Leben Labs)	$ 0.26
Libitus Plus TerbutalineSulphate 1.25mg, BromhexineHCl 4mg, Guaiphenesin 50mg SYR / 100ml (Leben Labs)	$ 0.38
LIBITUS PLUS SYRUP 1 bottle / 60 ML syrup each (Leben Labs)	$ 0.33
LIBITUS PLUS SYRUP 1 bottle / 100 ML syrup each (Leben Labs)	$ 0.48
LIBITUS PLUS syr 100ml (Leben Labs)	$ 0.38
LIBITUS PLUS syr 60ml (Leben Labs)	$ 0.26
Libitus Plus Syrup (Leben Labs)	$ 0.48
See 479 substitutes for Fei Ke Tan

References

1. DailyMed. "TERBUTALINE SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
2. PubChem. "terbutaline". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
3. DrugBank. "terbutaline". http://www.drugbank.ca/drugs/DB00871 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Fei Ke Tan are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Fei Ke Tan. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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Information checked by Dr. Sachin Kumar, MD Pharmacology