What happens if I overdose Fusiwal-B?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
An overdose of beclomethasone is not expected to produce life threatening symptoms. However, long term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.
Overdose of Fusiwal-B in details
When used at excessive doses, systemic corticosteroid effects eg, hypercorticism and adrenal suppression may occur. If such changes occur, Fusiwal-B should be discontinued slowly, consistent with acceptable procedures of discontinuing oral steroid therapy. The acute toxicity of beclomethasone dipropionate is low.
What should I avoid while taking Fusiwal-B?
Avoid getting this medication in your eyes. If this does happen, rinse with water and call your doctor.
Beclomethasone nasal can lower the blood cells that help your body fight infections. Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using beclomethasone nasal.
Fusiwal-B warnings
The replacement of a systemic corticosteroid with beclomethasone dipropionate nasal inhaler or spray can be accompanied by signs of adrenal insufficiency.
Careful attention must be given when patients previously treated for prolonged periods with systemic corticosteroids are transferred to beclomethasone dipropionate nasal inhaler or spray. This is particularly important in those patients who have associated asthma or other clinical conditions where too rapid a decrease in systemic corticosteroids may cause a severe exacerbation of their symptoms.
Studies have shown that combined administration of alternate-day prednisone systemic treatment and orally inhaled beclomethasone dipropionate increases the likelihood of HPA suppression compared to a therapeutic dose of either one alone. Therefore, nasal forms of beclomethasone dipropionate should be used with caution in patients already on alternate day prednisone regimens for any disease.
If recommended doses of intranasal beclomethasone are exceeded or if individuals are particularly sensitive or predisposed by virtue of recent systemic steroid therapy, symptoms of hypercorticism may occur, including very rare cases of menstrual irregularities, acneform lesions, cataracts, and cushingoid features. If such changes occur, this drug should be discontinued slowly consistent with accepted procedures for discontinuing oral steroid therapy.
Persons who are on drugs that suppress the immune system are more susceptible to infections than healthy individuals. Chickenpox and measles, for example, can have a more serious or even fatal course in nonimmune children or adults on corticosteroids. In such children or adults who have not had these diseases, particular care should be taken to avoid exposure of these infectious agents. How the dose, route, and duration of corticosteroid administration affects the risk of developing a disseminated infection is not known. The contribution of the underlying disease and/or prior corticosteroid treatment to the risk of developing a more severe infection is also not known. If exposed to chickenpox, prophylaxis with varicella zoster immune globulin (VZIG) may be indicated. If exposed to measles, prophylaxis with pooled intramuscualr immunoglobulin (IG), may be indicated. If chickenpox develops, treatment with antiviral agents may be considered.
What should I discuss with my healthcare provider before taking Fusiwal-B?
You should not use this medication if you are allergic to beclomethasone.
Before using beclomethasone, tell your doctor if you have been sick or have had an infection of any kind. You may not be able to use beclomethasone nasal until you are well.
To make sure you can safely use beclomethasone, tell your doctor if you have any of these other conditions:
- glaucoma or cataracts;
- herpes simplex virus of your eyes;
- tuberculosis or any other infection or illness;
- sores or ulcers inside your nose; or
- if you have recently had injury of or surgery on your nose.
FDA pregnancy category C. It is not known whether beclomethasone will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
It is not known whether beclomethasone passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Steroid medicines can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using beclomethasone nasal.
Fusiwal-B should not be given to a child younger than 6 years old. Qnasl should not be given to a child younger than 12 years old.
Fusiwal-B precautions
Patients should be instructed to use inhaler properly to ensure that the drug reaches the target areas within the lungs. Patients should also be made aware of the prophylactic nature of therapy with Fusiwal-B dipropionate HFA inhaler and that patients should use it regularly even when they are asymptomatic. Fusiwal-B dipropionate is not suitable for the treatment of an acute asthma attack.
Replacement of systemic steroid treatment with inhaled therapy sometimes unmasks allergies eg, allergic rhinitis or eczema previously controlled by the systemic drug.
Use in pregnancy: There are no adequate and well-controlled studies in pregnant women. Fusiwal-B dipropionate should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Use in lactation: It is reasonable to assume that Fusiwal-B dipropionate is secreted in milk but at the dosage used for direct inhalation, there is low potential for significant level in breast milk.
The use of Fusiwal-B dipropionate in breastfeeding mothers requires that the therapeutic benefits of the drug should be outweighed against the potential hazards to the mother and baby.
What happens if I miss a dose of Fusiwal-B?
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
References
- DrugBank. "fusidic acid". http://www.drugbank.ca/drugs/DB02703 (accessed September 17, 2018).
- MeSH. "Protein Synthesis Inhibitors". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology
