Gadoxetic Acid indications
CNS (CENTRAL NERVOUS SYSTEM)
OptiMARK™ Injection is indicated for use with magnetic resonance imaging (MRI) in patients with abnormal blood brain barrier or abnormal vascularity of the brain, spine and associated tissues.
Liver
OptiMARK™ Injection is indicated for use with MRI to provide contrast enhancement and facilitate visualization of lesions with abnormal vascularity in the liver in patients who are highly suspect for liver structural abnormalities on computed tomography.
Gadoxetic Acid description
Gadoxetic Acid (gadoxetate) is a paramagnetic gadolinium-containing contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection. Ethoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and forms a stable complex with it to make up the drug. It is marketed by Bayer HealthCare Pharmaceuticals and FDA approved on July 3, 2008.
Gadoxetic Acid interactions
Drug interactions have not been studied.
Gadoxetic Acid side effects
Headache, Pain Abdomen, Asthenia, Pain Back, Cardiovascular: Vasodilatation, Digestive : Nausea, Diarrhea, Dyspepsia, Injection Site : Injection Site Reaction,Musculoskeletal, Nervous System : Dizziness, Paresthesia, Respiratory : Rhinitis, Skin and Appendages, Special Senses : Taste Perversion
Gadoxetic Acid contraindications
OptiMARK™ Injection is contraindicated in patients at risk for nephrogenic systemic fibrosis (NSF). This includes patients with acute or chronic severe renal insufficiency (glomerular filtration rate <30 mL/min/1.73m2) and patients with acute renal insufficiency of any severity due to the hepato-renal syndrome or in the perioperative liver transplantation period. In these patients, avoid use of other gadolinium-based contrast agents unless the diagnostic information is essential and not available with non-contrast enhanced MRI. If a contrast-enhanced MRI is essential for a patient at risk for NSF, then a gadolinium-based contrast agent other than OptiMARK™ Injection should be used.
OptiMARK™ Injection is contraindicated in patients with known allergic or hypersensitivity reactions to gadolinium, versetamide, or any of the inert ingredients.
Active ingredient matches for Gadoxetic Acid:
Gadoxetic Acid
List of Gadoxetic Acid substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| EOB Primovist (Japan) | |
| Primovist (Australia, Austria, Bulgaria, Canada, China, Croatia (Hrvatska), Czech Republic, Estonia, Finland, Germany, Greece, Hungary, Italy, Latvia, Lithuania, Luxembourg, Malta, Norway, Poland, Romania, Russian Federation, Serbia, Slovenia, South Korea, Spain, Sweden, Switzerland, Turkey, United Kingdom) | |
| Injectable; Injection; Gadoxetic Acid / Gadoxetate Sodium 0.25 mmol / ml (Bayer) | |
| Primovist 0.25 mmol/1 mL x 1's (Bayer) | |
| Primovist solution 181.43 mg (Bayer) | |
| Primovist 0.25 mmol/ml (Austria, Germany, Hungary, Switzerland) | |
| Primovist 181.43mg/ml (Luxembourg) | |
| Primovist EOB (Japan) | |
| Primovist PFS | |
| Injectable; Injection; Gadoxetic Acid / Gadoxetate Sodium 0.25 mmol / ml | |
References
- PubChem. "Gadoxetic acid". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Gadoxetic acid". http://www.drugbank.ca/drugs/DB08884 (accessed September 17, 2018).
- MeSH. "Contrast Media". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Gadoxetic Acid are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Gadoxetic Acid. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
