Hibicet Uses

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Hibicet indications

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Hibicet is an anti-microbial preparation with cleansing properties for general antiseptic purposes. ( e.g wounds, burns, preoperative skin preparation... etc )..

Hibicet description

A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.

Hibicet dosage

The treatment by Hibicet Triton Health Care is with a standard diet for patients with hypercholesterolemia. The dose is determined individually, depending on the initial cholesterol levels. This medication is taken orally. The initial dose is usually 10 mg 1 time / day. The effect is manifested within 2 weeks, and the maximum effect is for 4 weeks. If necessary, the dose can be gradually increased every 4 weeks or more. The maximum daily dose is 80 mg.

Hibicet interactions

When this drug applied simultaneously with:

- digoxin slightly increased concentration of digoxin in plasma.

- itraconazole greatly increases the concentration of atorvastatin in plasma, apparently due to inhibition of itraconazole its metabolism in the liver that occurs with the participation of isoenzyme CYP3A4; increased risk of myopathy.

- colestipol may decrease the concentration of atorvastatin in plasma, with lipid-lowering effect is enhanced.

- antacids containing magnesium hydroxide and aluminum hydroxide, reduce the concentration of atorvastatin by approximately 35%.

- cyclosporine, fibrates (including gemfibrozil), azole antifungals derivatives, nicotinic acid increases the risk of myopathy.

- erythromycin, clarithromycin moderately increased concentrations of atorvastatin in plasma, increases the risk of myopathy.

- ethinyl estradiol, norethisterone (norethindrone) slightly increases the concentration of ethinyl estradiol, norethisterone and (norethindrone) in blood plasma.

- protease inhibitors increases the concentration of Hibicet Triton Health Care in plasma, as protease inhibitors are inhibitors of the CYP3A4 isoenzyme.

Diltiazem, verapamil, isradipine inhibit isoenzyme CYP3A4, which participates in the metabolism of Hibicet Triton Health Care, so that while the use of these calcium channel blockers may increase the concentration of atorvastatin in plasma and increased risk of myopathy.

Hibicet side effects

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Chlorhexidine (Hibicet) and Cetrimide (Hibicet) Irrigation Solution helps most people when used for washing and cleansing the skin or wounds, but it may have some unwanted side-effects in a few people.

All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.

Tell your doctor if you experience a skin rash or reaction. If you get a skin rash it may be because you have had an allergic reaction to the irrigation. If this is the case, you should no longer use this irrigation.

Tell your doctor, nurse or pharmacist as soon as possible if you feel anything unusual during or after Chlorhexidine (Hibicet) and Cetrimide (Hibicet) Irrigation Solution has been used.

Hibicet contraindications

Liver disease in the active phase, increasing the serum transaminase activity more than 3 times of unknown origin, pregnancy, lactation (breastfeeding), hypersensitivity to atorvastatin. Women of reproductive age not using reliable contraception.

Active ingredient matches for Hibicet:

Cetrimide/Chlorhexidine in Greece, Netherlands, Thailand, United Kingdom.

Cetrimide/Chlorhexidine gluconate in Italy.


List of Hibicet substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Liquid; Topical; Chlorhexidine Gluconate 1.5%; Cetrimide 15% (Astrazeneca)
Inhibac Hospital Conc 5 L
Iteol 3 Skin 115 ml Solution (Astra Zeneca Pharma India Limited)$ 0.19
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Iteol 3 Skin 1000 ml Solution (Astra Zeneca Pharma India Limited)$ 1.21
Iteol-3 Cetrimide Strong 40%7.5%v/v, ChlorhexidineStrong40% 1.5% v/v SOLN / 115ml (AstraZeneca)$ 0.19
Iteol-3 Cetrimide Strong 40%7.5%v/v, ChlorhexidineStrong40% 1.5% v/v SOLN / 11 (AstraZeneca)$ 1.21
Iteol-3 Cetrimide 40% 7.5 % v/v, Chlorhexidine 40% 1.5 % v/v. SOLN / 115ml (AstraZeneca)$ 0.19
Iteol-3 Cetrimide 40% 7.5 % v/v, Chlorhexidine 40% 1.5 % v/v. SOLN / 1l (AstraZeneca)$ 1.21
115ml (AstraZeneca)$ 0.19
1l (AstraZeneca)$ 1.21
Iteol-3 Cetrimide Strong 40%7.5%v/v, ChlorhexidineStrong 40% 1.5% v/v SOLN / 115ml (AstraZeneca)$ 0.19
Iteol-3 Cetrimide Strong 40%7.5%v/v, ChlorhexidineStrong 40% 1.5% v/v SOLN / 11 (AstraZeneca)$ 1.21
ITEOL-3 topical soln 1000ml (AstraZeneca)$ 1.21
ITEOL-3 topical soln 115ml (AstraZeneca)$ 0.19
ITEOL-3 1.5%/7.5% LIQUID 1 bottle / 1000 ML liquid each (Astra Zeneca)$ 1.33
Killa 1 gal
MICROGARD SOLUTION 1 bottle / 500 ML solution each (Stedman Pharmaceuticals Pvt Ltd)$ 4.26
100ml (J & J)$ 0.59
500ml (J & J)$ 2.36
MICROSHIELD ANTISEPTIC CONC. topical soln 100ml (J & J)$ 0.59
MICROSHIELD ANTISEPTIC CONC. topical soln 500ml (J & J)$ 2.36
Neo Resiguard 5 L x 1's (Nicholas)$ 80.60
NEW ITEOL LIQUID 1 bottle / 1000 ML liquid each (Astra Zeneca)$ 1.37
Soap Substitute; Topical; Chlorhexidine Gluconate 0.15%; Cetrimide 1.5% (Ferndale)
Soap Substitute; Topical; Chlorhexidine Gluconate 0.15%; Cetrimide 1.5%
RAVLON 3%/1.5% SOLUTION 1 bottle / 100 ML solution each (Jan Aushadhi)$ 0.27
Cream; Topical; Cetrimide 0.5%; Chlorhexidine Hydrochloride 0.1% (Triton (Calyx))
Savior 10mg TAB / 10 (Triton (Calyx))$ 0.96
Savior 20mg TAB / 10 (Triton (Calyx))

References

  1. DailyMed. "CHLORHEXIDINE GLUCONATE; ISOPROPYL ALCOHOL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "chlorhexidine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "chlorhexidine". http://www.drugbank.ca/drugs/DB00878 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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