What is Hipo Sport?
Hipo Sport is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and other symptoms of arthritis of the joints (eg, osteoarthritis), such as inflammation, swelling, stiffness, and joint pain. However, Hipo Sport does not cure osteoarthritis and will help you only as long as you continue to use it.
Hipo Sport topical 3% gel is also used to treat actinic keratosis, a skin problem that may become cancerous if not treated. The exact way that topical Hipo Sport helps this condition is unknown.
Hipo Sport topical solution is used to treat pain and swelling caused by osteoarthritis of the knees.
Hipo Sport topical patch is used to treat acute pain caused by minor strains, sprains, and contusions (bruises).
Hipo Sport is available only with your doctor's prescription.
Hipo Sport indications
Intramuscular
Renal colic
Adult: As Hipo Sport Na: 75 mg, may repeat once after 30 min if needed. Max: 150 mg/day. Max period: 2 days.
Intramuscular
Bursitis, Pain and inflammation associated with musculoskeletal and joint disorders, Rheumatoid arthritis, Sprains, Strains, Tendinitis, Acute gout, Dysmenorrhoea
Adult: As Hipo Sport Na: 75 mg once daily, injected into the gluteal muscle, may increase to 75 mg bid in severe conditions. Max period: 2 days.
Intravenous
Postoperative pain
Adult: As Hipo Sport Na: 75 mg infusion in glucose 5% or NaCl 0.9% (previously buffered w/ Na bicarbonate) given over 30-120 min or as bolus inj, may repeat after 4-6 hr if necessary. Max period: 2 days.
Intravenous
Prophylaxis of postoperative pain
Adult: As Hipo Sport Na: Initially, 25-50 mg infusion given after surgery over 15-60 min followed by 5 mg/hr. Alternatively, initial dose may be given as bolus inj over 5-60 sec followed by additional inj, may repeat after 4-6 hr if necessary. Max: 150 mg/day. Max period: 2 days.
Ophthalmic
Postoperative ocular inflammation
Adult: As Hipo Sport Na (0.1% soln): Instill into the appropriate eye 4 times daily starting 24 hr after surgery for up to 28 days.
Ophthalmic
Inflammation and discomfort after strabismus surgery
Adult: As Hipo Sport Na (0.1% soln): Instill 1 drop 4 times daily for the 1st wk; then tid in the 2nd wk, bid in the 3rd wk, and as required for the 4th wk.
Ophthalmic
Pain and discomfort after radial keratotomy
Adult: As Hipo Sport Na (0.1% soln): Instill 1 drop before surgery followed by 1 drop immediately after surgery, and then 1 drop 4 times daily for up to 2 days.
Ophthalmic
Pain after accidental trauma
Adult: As Hipo Sport Na (0.1% soln): Instill 1 drop 4 times daily for up to 2 days.
Ophthalmic
Control of inflammation after argon laser trabeculoplasty
Adult: As Hipo Sport Na (0.1% soln): Instill 1 drop 4 times during the 2 hr before procedure followed by 1 drop 4 times daily, up to 7 days after procedure.
Ophthalmic
Prophylaxis of intra-operative miosis
Adult: As Hipo Sport Na (0.1% soln): Instill into appropriate eye 4 times w/in 2 hr before surgery.
Ophthalmic
Post-photorefractive keratectomy pain
Adult: As Hipo Sport Na (0.1% soln): Instill into the affected eye twice, an hr before surgery, then 1 drop twice at 5-min intervals immediately after surgery, then every 2-5 hr while awake for up to 24 hr.
Ophthalmic
Seasonal allergic conjunctivitis
Adult: As Hipo Sport Na (0.1% soln): Instill 1 drop before surgery followed by 1 drop immediately after surgery, and then 1 drop 4 times daily for up to 2 days.
Oral
Bursitis, Pain and inflammation associated with musculoskeletal and joint disorders, Rheumatoid arthritis, Sprains, Strains, Tendinitis, Acute gout, Dysmenorrhoea
Adult: As Hipo Sport Na: 75-150 mg/day in divided doses. Max: 150 mg/day.
Oral
Migraine
Adult: As Hipo Sport K: Initially, 50 mg taken at the 1st sign of an attack, an additional dose of 50 mg may be taken after 2 hr if symptoms persist. If needed, further doses of 50 mg may be taken 4-6 hrly. Max: 200 mg/day.
Rectal
Acute gout, Bursitis, Dysmenorrhoea, Pain and inflammation associated with musculoskeletal and joint disorders, Rheumatoid arthritis, Sprains, Strains, Tendinitis
Adult: As Hipo Sport Na: 100 mg once daily.
Topical/Cutaneous
Actinic keratoses
Adult: As Hipo Sport Na (3% gel): Apply bid for 60-90 days.
Topical/Cutaneous
Osteoarthritis
Adult: As Hipo Sport Na (1.6% soln): Apply in small amounts (20 or 40 drops) onto affected area 4 times daily. As Na: (1% gel): Apply to the affected area 4 times daily. Max: 32 g/day over the affected area.
Topical/Cutaneous
Local symptomatic relief of pain and inflammation
Adult: As Hipo Sport Na (1% gel): Apply onto affected area 3 or 4 times daily.
Transdermal
Acute pain
Adult: Sprains, strains, contusions: 1 patch bid.
How should I use Hipo Sport?
Use Hipo Sport solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Hipo Sport solution comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Hipo Sport solution refilled.
- Do not apply Hipo Sport solution to infected skin; open wounds; or red, swollen, or peeling skin.
- Wash your hands immediately before and after using Hipo Sport solution.
- Wash the affected area and dry completely before using Hipo Sport solution.
- To apply Hipo Sport solution, dispense 10 drops at a time onto the knee or into your hand. Spread Hipo Sport solution evenly around the front, back, and sides of the knee. Repeat until you have used the whole dose.
- Be sure that you cover your entire knee with your dose of Hipo Sport solution. Do not use more than the recommended amount.
- Do not apply sunscreens, cosmetics, insect repellants, other topical medicines, or any other substance to the treated area until it is completely dry.
- Do not put on clothes over the treated area until it is completely dry.
- Do not wrap, bandage, or apply heat to the treated area.
- Let the treated skin dry before touching it or letting it touch anyone else's skin.
- Do not shower, bathe, or wash the treated area for at least 30 minutes after you use Hipo Sport solution.
- If you miss a dose of Hipo Sport solution, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Hipo Sport solution.
Uses of Hipo Sport in details
Hipo Sport is used to relieve pain from various conditions. This form of Hipo Sport is used to treat migraine headaches. Hipo Sport is a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking your body's production of certain natural substances that cause inflammation. This effect helps to decrease swelling, pain, or fever.
OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.
This medication may also be used to treat gout attacks.
How to use Hipo Sport
Read the Medication Guide provided by your pharmacist before you start taking Hipo Sport and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth as directed by your doctor. Empty the contents of one packet into a cup containing 1 to 2 ounces (30 to 60 milliliters) of water. Mix well and drink all of it right away. Do not mix with any liquid other than water. If stomach upset occurs while taking this medication, take it with food, milk, or an antacid. However, if you take this medication with a meal high in fat, it may not work as well.
There are different brands and forms of this medication available. Because different forms do not have the same effects at equal strengths, do not switch forms of Hipo Sport unless your doctor tells you to.
To reduce your risk of stomach bleeding and other side effects, take this medication at the lowest effective dose. Do not increase your dose or take it more often than prescribed.
Pain medications work best if they are used as the first signs of pain occur. If you wait until the pain has worsened, the medication may not work as well.
Tell your doctor if your condition persists or worsens.
Hipo Sport description
The active substance is sodium-[o[(2,6-dichlorophenyl)-amino]-phenyl]-acetate (= Hipo Sport sodium).
Each enteric tablet contains 25 mg or 50 mg of Hipo Sport sodium.
One prolonged-release tablet contains 100 mg of Hipo Sport sodium.
Excipients/Inactive Ingredients: Gastro-Resistant Tablet: Core for 25 mg and 50 mg: Cellulose microcrystalline; lactose monohydrate; magnesium stearate; maize starch; povidone; silica, colloidal anhydrous; sodium starch glycolate (type A).
Coating for 25 mg and 50 mg: Hypromellose; iron oxide yellow (E172); macrogoglycerol hydroxystearate; methacrylic acid-ethyl acrylate copolymer; macrogol 8000; talc; titanium dioxide (E171); simeticone; alpha-octadecyl-omega-hydroxy-polyglykolether; sorbic acid.
Coating for 50 mg: Iron oxide red (E172).
SR Tablet: Tablet Core: Cetyl alcohol; magnesium stearate; povidone; silica; colloidal anhydrous; sucrose.
Tablet Coating: Hypromellose; iron oxide red (E172); macrogol 8000; polysorbate 80; sucrose; talc; titanium dioxide (E171). Printing Ink: Carbon black, shellac, ammonium hydroxide, simethicone.
Injection: Each ampoule also contains the following excipients: Mannitol, sodium metabisulfite (E223), benzyl alcohol, propylene glycol, water for injection, sodium hydroxide.
Hipo Sport dosage
General Dosing Instructions
Carefully consider the potential benefits and risks of Hipo Sport and other treatment options before deciding to use Hipo Sport. Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals.
The effectiveness of Hipo Sport when taken with food has not been studied in clinical studies. Taking Hipo Sport with food may cause a reduction in effectiveness compared to taking Hipo Sport on an empty stomach.
Acute Pain
For management of mild to moderate acute pain, the dosage is 18 mg or 35 mg orally three times daily.
Osteoarthritis Pain
For management of osteoarthritis pain, the dosage is 35 mg orally three times daily.
Dosage Adjustments in Patients with Hepatic Impairment
Patients with hepatic disease may require reduced doses of Hipo Sport compared to patients with normal hepatic function. As with other Hipo Sport products, start treatment at the lowest dose. If efficacy is not achieved with the lowest dose, discontinue use.
Non-Interchangeability with Other Formulations of Hipo Sport
Hipo Sport capsules are not interchangeable with other formulations of oral Hipo Sport even if the milligram strength is the same. Hipo Sport capsules contain Hipo Sport free acid whereas other Hipo Sport products contain a salt of Hipo Sport, i.e., Hipo Sport potassium or sodium. A 35 mg dose of Hipo Sport is approximately equal to 37.6 mg of sodium Hipo Sport or 39.5 mg of potassium Hipo Sport. Therefore, do not substitute similar dosing strengths of other Hipo Sport products without taking this into consideration.
Hipo Sport interactions
See also:
What other drugs will affect Hipo Sport?
Aspirin: Concomitant administration of Hipo Sport and aspirin is not recommended because Hipo Sport is displaced from its binding sites during the concomitant administration of aspirin, resulting in lower plasma concentrations, peak plasma levels and AUC values.
Anticoagulants: While studies have not shown Hipo Sport to interact with anticoagulants of the warfarin type, caution should be exercised, nonetheless, since interactions have been seen with other NSAIDs. Because prostaglandins play an important role in hemostasis and NSAIDs affect platelet function as well, concurrent therapy with all NSAIDs, including Hipo Sport and warfarin, requires close monitoring of patients to be certain that no change in their anticoagulant dosage is required.
Digoxin, Methotrexate, Cyclosporine: Hipo Sport, like other NSAIDs, may affect renal prostaglandins and increase the toxicity of certain drugs. Ingestion of Hipo Sport may increase serum concentrations of digoxin and methotrexate and increase cyclosporine's nephrotoxicity. Patients who begin taking Hipo Sport or who increase their Hipo Sport dose or any other NSAID while taking digoxin, methotrexate or cyclosporine may develop toxicity characteristics for these drugs. They should be observed closely, particularly if renal function is impaired. In the case of digoxin, serum levels should be monitored.
Lithium: Hipo Sport decreases lithium renal clearance and increases lithium plasma levels. In patients taking Hipo Sport and lithium concomitantly, lithium toxicity may develop.
Oral Hypoglycemics:
Hipo Sport does not alter glucose metabolism in normal subjects nor does it alter the effects of oral hypoglycemic agents. There are rare reports, however, from marketing experiences, of changes in effects of insulin or oral hypoglycemic agents in the presence of Hipo Sport that necessitated changes in the doses of such agents. Both hypo- and hyperglycemic effects have been reported. A direct causal relationship has not been established, but physicians should consider the possibility that Hipo Sport may alter a diabetic patient's response to insulin or oral hypoglycemic agents.Diuretics: Hipo Sport and other NSAIDs can inhibit the activity of diuretics. Concomitant treatment with potassium-sparing diuretics may be associated with increased serum potassium levels.
Other Drugs: In small groups of patients (7-10/interaction study), the concomitant administration of azathioprine, gold, chloroquine, D-penicillamine, prednisolone, doxycycline or digitoxin did not significantly affect the peak levels and AUC values of Hipo Sport. Phenobarbital toxicity has been reported to have occurred in a patient on chronic phenobarbital treatment following the initiation of Hipo Sport therapy.
Hipo Sport side effects
See also:
What are the possible side effects of Hipo Sport?
There have been cases reported of Hipo Sport being associated with the development of symptoms resembling the syndrome of inappropriate antidiuretic hormone secretion in elderly women. A patient who had been taking Hipo Sport for several years and had increasingly complained of dry, gritty eyes noticed that eye irritation disappeared within 3 days when Hipo Sport had to be discontinued because of GI effects.
The most frequent adverse effects reported in patients given Hipo Sport are GI in nature. Typical reactions include epigastric pain, nausea, vomiting and diarrhoea. Rarely, peptic ulcer and GI bleeding have occurred. Hipo Sport has also been implicated as the causative agent in colonic ulceration, small bowel perforation and pseudomembranous colitis.
Renal papillary necrosis and nephritic syndrome have been reported in patients taking Hipo Sport. Elevations of serum aminotransferase activity and clinical hepatitis, including fetal fulminant hepatitis have occurred in patients taking Hipo Sport. Self-limiting skin reaction eg, rash or pruritus may occur in patients given Hipo Sport.
Aspirin-sensitive asthmatic patients have developed reactions (rhinorrhoea, tightness of chest, wheezing, dyspnoea) when challenged with Hipo Sport in doses of 10-25 mg and the CMS in the UK have received a report of 1 aspirin-sensitive patient who died from acute asthma 4 hrs after a single 25-mg dose of Hipo Sport.
Hipo Sport contraindications
See also:
What is the most important information I should know about Hipo Sport?
Hypersensitivity to Hipo Sport sodium or to any of the excipients of Hipo Sport.
Active gastric or intestinal ulcer, bleeding or perforation.
Last trimester of pregnancy.
Hepatic, renal and severe cardiac failure.
Patients in whom attacks of asthma, urticaria or acute rhinitis are precipitated by acetylsalicylic acid and/or other drugs with prostaglandin-synthetase inhibitory activity.
Treatment of peri-operative pain in setting of coronary artery bypass graft (CABG) surgery.
The use of high dose Hipo Sport (150 mg/day) for >4 weeks is contraindicated in patients with established cardiovascular disease (congestive heart failure, established ischemic heart disease, peripheral arterial disease) or uncontrolled hypertension.
Established Cardiovascular Disease or Significant Cardiovascular Risk Factors: The use of high dose Hipo Sport (150mg/day) for >4 weeks is contraindicated in patients with established cardiovascular disease (congestive heart failure, established ischemic heart disease, peripheral arterial disease) or uncontrolled hypertension. If Hipo Sport treatment is needed, patients with established cardiovascular disease, uncontrolled hypertension or significant cardiovascular risk factors (eg, hypertension, hyperlipidaemia, diabetes mellitus and smoking) should be treated only after careful consideration and at doses ≤100 mg daily if the treatment is for >4 weeks. As the cardiovascular risks of Hipo Sport may increase with dose and duration of exposure, Hipo Sport should always be prescribed at the lowest effective daily dose and for the shortest duration possible.
Renal Impairment: Hipo Sport is contraindicated in patients with renal failure. No specific studies have been carried out in patients with renal impairment, therefore, no specific dose adjustment recommendations can be made. Caution is advised when administering Hipo Sport to patients with mild to moderate renal impairment.
Hepatic Impairment: Hipo Sport is contraindicated in patients with hepatic failure. No specific studies have been carried out in patients with hepatic impairment, therefore, no specific dose adjustment recommendations can be made. Caution is advised when administering Hipo Sport to patients with mild to moderate hepatic impairment.
Active ingredient matches for Hipo Sport:
Diclofenac in Mexico.
Diclofenac diethylamine in Mexico.
| Unit description / dosage (Manufacturer) | Price, USD |
| Gel; Topical; Diclofenac Diethylamine 1.16% | |
List of Hipo Sport substitutes (brand and generic names): | |
| Hifenac (Bangladesh) | |
| Hifenac 1.5% w/w Gel (Intas Pharmaceuticals Ltd.) | $ 0.89 |
| Hit (Ecuador) | |
| Hitflam (Bangladesh) | |
| Hitflam-SR (Bangladesh) | |
| Holactiv (Portugal) | |
| Hooky (India) | |
| Hooky Diclofenac diethylammonium, linseed oil, methylsalicylate, menthol. OINT / 30g (Neiss) | $ 0.72 |
| 30g (Neiss) | $ 0.72 |
| HOOKY oint 30g (Neiss) | $ 0.72 |
| HOOKY INJ (India) | |
| HOOKY INJ inj 75 mg x 1 mL x 1ml (Neiss) | $ 0.18 |
| Huma-Difenac (Hungary) | |
| Hyclo-S (India) | |
| Hyclo-S Diclofenac sodium 50 mg, Serratiopeptidase 10 mg. TAB / 10 (Sunrise) | $ 0.71 |
| 10's (Sunrise) | $ 0.71 |
| HYCLO-S tab 10's (Sunrise) | $ 0.71 |
| I Gesic | |
| I Gesic Eye 5 ml Drop (Praggya (Centaur Pharmaceuticals)) | $ 0.05 |
| I GESIC 0.1% EYE DROP 1 packet / 5 ML eye drop each (Praggya (Centaur Pharmaceuticals)) | $ 0.40 |
| I Gesic 0.1% Eye Drop (Praggya (Centaur Pharmaceuticals)) | $ 0.40 |
| I-Gesic (India) | |
| 0.1 % w/v x 5ml (Centaur (Praggya)) | $ 0.27 |
| I-Gesic 0.1% w/v EYE-DPS / 5ml (Centaur (Praggya)) | $ 0.27 |
| Drops; Ophthalmic; Diclofenac Sodium 0.1% (Centaur (Praggya)) | |
| I-Gesic 0.1 % w/w x 1 Bottle nhöïa lupolene 5 mL (Centaur (Praggya)) | |
| I-GESIC eye drops 0.1 % w/v x 5ml (Centaur (Praggya)) | $ 0.27 |
| Ibuxim Diclo (Argentina) | |
| ICEFLAM | |
| ICEFLAM INJECTION 1 vial / 3 ML injection each (Shrinivas Gujarat Laboratories Pvt Ltd) | $ 0.14 |
| Iclonac (India) | |
| ICLONAC inj 75 mg x 1 mL x 1ml (SRK) | $ 0.24 |
| ICLONAC tab 50 mg x 10's (SRK) | |
| ICONAC | |
| ICONAC INJECTION 1 vial / 3 ML injection each (Mesmer (Icon)) | $ 0.11 |
| ICONAC topical gel 30g (Mesmer (Icon)) | $ 0.70 |
| Iglodine (Argentina) | |
| Iglodine 75 (Argentina) | |
| Ignorin (Sweden) | |
| Ijm-Gel (India) | |
| Ijm-Gel Diclofenac diethylammonium1.16 % w/w, Methyl salicylate10 % w/w, Menthol 5 % w/w, linseed oil 3 % w/w. GEL / 30g (Candor (Edric)) | |
| 30g (Candor (Edric)) | |
| IJM-GEL topical gel 30g (Candor (Edric)) | |
| Imanol (Argentina) | |
| Imflac (Australia) | |
| Tablet, Enteric Coated; Oral; Diclofenac Sodium (Douglas) | |
| Tablets, Enteric Coated; Oral; Diclofenac Sodium (Douglas) | |
| Imflac Anti-Inflammatory Pain Relief Gel | |
| Gel; Topical; Diclofenac Sodium 1% | |
| Imflamol SR | |
| Imflamol SR 100 mg Tablet (Panjon Pharma Ltd) | $ 0.02 |
| Inac (India, Singapore) | |
| INAC Capsule/ Tablet / 50mg / 10 units (Zydus Alidac (Zydus Cadila Healthcare Ltd)) | $ 0.13 |
| INAC Injection / 75mg / 3ml units (Zydus Alidac (Zydus Cadila Healthcare Ltd)) | $ 0.06 |
| INAC Capsule/ Tablet / 100mg / 10 units (Zydus Alidac (Zydus Cadila Healthcare Ltd)) | $ 0.26 |
| Inac 50 mg x 1000's (Zydus Alidac (Zydus Cadila Healthcare Ltd)) | |
See 7834 substitutes for Hipo Sport | |
References
- DailyMed. "DICLOFENAC EPOLAMINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "diclofenac". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "diclofenac". http://www.drugbank.ca/drugs/DB00586 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Hipo Sport are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Hipo Sport. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yetConsumer reported age
No survey data has been collected yetConsumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
