Hydretic is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.
Hydretic is also used to treat fluid retention (edema) that is caused by congestive heart failure, severe liver disease (cirrhosis), kidney disease, or treatment with a steroid or hormone medicine.
Hydretic is a thiazide diuretic (water pill). It is used to help reduce the amount of water in the body by increasing the flow of urine. It may also be used for other conditions as determined by your doctor.
Hydretic is available only with your doctor's prescription.
Hydretic indications
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Hydretic (Hydretic capsule) is indicated in the management of hypertension either as the sole therapeutic agent, or in combination with other antihypertensives. Unlike potassium sparing combination diuretic products, Hydretic (Hydretic capsule) may be used in those patients in whom the development of hyperkalemia cannot be risked, including patients taking ACE inhibitors.
Usage in Pregnancy
The routine use of diuretics in an otherwise healthy woman is inappropriate and exposes mother and fetus to unnecessary hazard. Diuretics do not prevent development of toxemia of pregnancy, and there is no satisfactory evidence that they are useful in the treatment of developed toxemia.
Edema during pregnancy may arise from pathological causes or from the physiologic and mechanical consequences of pregnancy. Diuretics are indicated in pregnancy when edema is due to pathologic causes, just as they are in the absence of pregnancy. Dependent edema in pregnancy resulting from restriction of venous return by the expanded uterus is properly treated through elevation of the lower extremities and use of support hose; use of diuretics to lower intravascular volume in this case is illogical and unnecessary. There is hypervolemia during normal pregnancy which is harmful to neither the fetus nor the mother (in the absence of cardiovascular disease), but which is associated with edema, including generalized edema in the majority of pregnant women. If this edema produces discomfort, increased recumbency will often provide relief. In rare instances this edema may cause extreme discomfort which is not relieved by rest. In these cases a short course of diuretics may provide relief and may be appropriate.
How should I use Hydretic?
Use Hydretic capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Take Hydretic capsules by mouth with or without food.
If you take colestipol or cholestyramine for high cholesterol, ask your doctor or pharmacist how to take it with Hydretic capsules.
Hydretic capsules may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.
If you miss a dose of Hydretic capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Hydretic capsules.
Uses of Hydretic in details
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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This medication is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Hydretic is a "water pill" (diuretic) that causes you to make more urine. This helps your body get rid of extra salt and water.
This medication also reduces extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, or kidney disease. This can lessen symptoms such as shortness of breath or swelling in your ankles or feet.
How to use Hydretic
Take this medication by mouth as directed by your doctor, usually once daily in the morning with or without food. It is best to avoid taking this medication within 4 hours of your bedtime to prevent having to get up to urinate.
The dosage is based on your medical condition and response to treatment.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.
Cholestyramine and colestipol can decrease the absorption of Hydretic. If you are taking either of these drugs, take them at least 4 hours before or after taking Hydretic.
Tell your doctor if your condition does not improve or if it worsens (for example, your blood pressure readings increase).
Hydretic description
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Each film-coated tablet contains losartan potassium 50 mg and Hydretic 12.5 mg.
Losartan potassium is 2-Butyl-4-chloro-1-[p-o-1H-tetrazol-5-yl-phenyl)benzyl]imidazole-5-methanol, potassium. Its empirical formula is C22H22ClKN6O and molecular weight is 461.
Hydretic is 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide. Its empirical formula is C7H8ClN3O4S2 and molecular weight is 297.7.
Hydretic dosage
Usual Adult Dose of Hydretic for Edema:
Usual dose: 25 mg to 100 mg orally once or twice daily
Comments:
-Some patients respond to intermittent therapy, (i.e., administration on alternate days or on 3 to 5 days each week). Excessive response and undesirable electrolyte imbalance are less likely to occur with intermittent dosing.
Usual Adult Dose of Hydretic for Hypertension:
Initial dose: 25 mg orally once daily
Maintenance dose: May increase to 50 mg orally daily, as a single or 2 divided doses
Comments:
-Patients usually do not require doses in excess of 50 mg daily when used concomitantly with other antihypertensive agents.
Usual Adult Dose of Hydretic for Nephrocalcinosis:
Initial: 25 mg orally once daily
Maintenance dose: May increase to 50 mg twice daily
Usual Adult Dose of Hydretic for Osteoporosis:
Initial: 25 mg orally once daily
Maintenance dose: May increase to 50 mg daily
Usual Adult Dose of Hydretic for Diabetes Insipidus:
Initial: 50 mg orally once daily
Maintenance dose: May increase to 100 mg orally daily
Usual Pediatric Dose of Hydretic for Edema:
Less than 6 months: Up to 3 mg/kg/day (up to 1.5 mg/pound) orally in 2 divided doses
Less than 2 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses
Maximum dose 37.5 mg per day
2 to 12 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses
Maximum dose 100 mg per day
Usual Pediatric Dose for Hypertension:
Less than 6 months: Up to 3 mg/kg/day (up to 1.5 mg/pound) orally in 2 divided doses
Less than 2 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses
Maximum dose 37.5 mg per day
2 to 12 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses
DIAMOX®. modifies phenytoin metabolism with increased serum levels of phenytoin. This may increase or enhance the occurrence of osteomalacia in some patients receiving chronic phenytoin therapy. Caution is advised in patients receiving chronic concomitant therapy.
By decreasing the gastrointestinal absorption of primidone, DIAMOX may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. Caution is advised when beginning, discontinuing, or changing the dose of DIAMOX in patients receiving primidone.
Because of possible additive effects with other carbonic anhydrase inhibitors, concomitant use is not advisable.
Hydretic may increase the effects of other folic acid antagonists.
Hydretic may increase or decrease blood glucose levels. Consideration should be taken in patients being treated with antidiabetic agents.
Hydretic decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect.
Hydretic reduces urinary excretion of quinidine and may enhance its effect.
Hydretic may prevent the urinary antiseptic effect of methenamine.
Hydretic increases lithium excretion and the lithium may be decreased.
Hydretic and sodium bicarbonate used concurrently increases the risk of renal calculus formation.
Applies to Hydretic: oral capsule, oral solution, oral tablet
As well as its needed effects, Hydretic (the active ingredient contained in Hydretic) may cause unwanted side effects that require medical attention.
Major Side Effects
If any of the following side effects occur while taking Hydretic, check with your doctor immediately:
Incidence not known:
Abdominal or stomach pain
back, leg, or stomach pains
black, tarry stools
bleeding gums
blistering, peeling, or loosening of the skin
bloating
blood in the urine or stools
bloody urine
blue lips and fingernails
blurred vision
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
chest pain
chills
clay-colored stools
cloudy urine
cold sweats
confusion
constipation
cough or hoarseness
coughing that sometimes produces a pink frothy sputum
coughing up blood
cracks in the skin
darkened urine
decrease in urine output or decrease in urine-concentrating ability
decreased frequency or amount of urine
diarrhea
difficult, fast, or noisy breathing, sometimes with wheezing
difficulty with breathing
difficulty with swallowing
dizziness, faintness, or lightheadedness when getting up from a lying or sitting position
dry mouth
fast or irregular heartbeat
fever
flushed, dry skin
fruit-like breath odor
general body swelling
general feeling of discomfort or illness
general feeling of tiredness or weakness
greatly decreased frequency of urination or amount of urine
headache
hives
increased blood pressure
increased hunger
increased sweating
increased thirst
increased urination
indigestion
itching
joint pain, stiffness, or swelling
loss of appetite
loss of heat from the body
lower back or side pain
muscle cramps or pain
nausea or vomiting
nosebleeds
numbness, tingling, pain, or weakness in the hands or feet
pain in the joints or muscles
painful or difficult urination
pains in the stomach, side, or abdomen, possibly radiating to the back
pale skin
pinpoint red spots on the skin
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
rash
red, irritated eyes
red skin lesions, often with a purple center
red, swollen skin
redness, soreness, or itching skin
scaly skin
seizures
shortness of breath
sore throat
sores, ulcers, or white spots on the lips or in the mouth
sores, welting, or blisters
sugar in the urine
swelling of the face, fingers, legs, ankles, feet, or lower legs
swollen or painful glands
tenderness of salivary glands
thickening of bronchial secretions
tightness in the chest
trembling
troubled breathing
unpleasant breath odor
unusual bleeding or bruising
unusual tiredness or weakness
unusual weight loss
vomiting of blood
weakness and heaviness of the legs
weight gain
wheezing
yellow eyes or skin
Minor Side Effects
Some Hydretic side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:
Incidence not known:
Cramping
decreased interest in sexual intercourse
difficulty having a bowel movement (stool)
feeling of constant movement of self or surroundings
hair loss or thinning of the hair
inability to have or keep an erection
increased sensitivity of the skin to sunlight
loss in sexual ability, desire, drive, or performance
You should not use this medication if you are allergic to Hydretic or if you are unable to urinate.
Before using this medication, tell your doctor if you have liver disease, kidney disease, glaucoma, asthma or allergies, gout, diabetes, or if you are allergic to sulfa drugs or penicillin.
Avoid drinking alcohol, which can increase some of the side effects of Hydretic.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.
There are many other drugs that can interact with Hydretic. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.
DailyMed. "AMLODIPINE BESYLATE; HYDROCHLOROTHIAZIDE; OLMESARTAN MEDOXOMIL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
The results of a survey conducted on ndrugs.com for Hydretic are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Hydretic. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
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