Iron Polymaltose Uses

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Iron Polymaltose indications

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Intramuscular

Iron-deficiency anaemia

Adult: As inj containing 100 mg iron as Iron Polymaltose/2 ml: Admin by ventro-gluteal inj according to Hochstetter method (refer to package insert for details). Total dose of iron needed (mg): Wt (kg) x (normal haemoglobin - actual haemoglobin in g/L) x 0.24 + iron depot. Iron depot calculated as 15 mg/kg up to a wt of about 34 kg, max of 500 mg for body wt ≥34 kg. May give dose as alternate day inj of 2 ml (or 4 ml at longer interval) until total dose is reached. Max single daily dose: >10-45 kg: 2 ml; >45 kg: 4 ml.

Child: As inj containing 100 mg iron as Iron Polymaltose/2 ml: Admin by ventro-gluteal inj according to Hochstetter method (refer to package insert for details).Total dose of iron needed (mg): Wt (kg) x (normal haemoglobin - actual haemoglobin in g/L) x 0.24 + iron depot. Iron depot calculated as 15 mg/kg up to a wt of about 34 kg, max of 500 mg for body wt ≥ 34 kg. Max single daily dose: >10-45 kg: 2 ml; 5-10 kg: 1 ml; infants (up to 5 kg): 0.5 ml.

Intravenous

Iron-deficiency anaemia

Adult: As inj containing 100 mg iron as Iron Polymaltose/2 ml: Total dose of iron needed (mg): Wt (kg) x (normal haemoglobin - actual haemoglobin in g/L) x 0.24 + iron depot. Iron depot calculated as 15 mg/kg up to a wt of about 34 kg, max of 500 mg for body wt ≥ 34 kg. Refer to product insert for dosage table. 1st 50 ml to be infused slowly (5-10 drops/minute) and observe patient closely. If well tolerated, increase rate to 30 drops/minute (based on drop volume of 0.067ml).

Child: As inj containing 100 mg iron as Iron Polymaltose/2 ml: Total dose of iron needed (mg): Wt (kg) x (normal haemoglobin - actual haemoglobin in g/L) x 0.24 + iron depot. Iron depot calculated as 15 mg/kg up to a wt of about 34 kg, max of 500 mg for body wt ≥ 34 kg. Refer to product insert for dosage table. 1st 50 ml to be infused slowly (5-10 drops/minute) and observe patient closely. If well tolerated, increase rate to 30 drops/minute (based on drop volume of 0.067ml).

Oral

Iron-deficiency anaemia

Adult: As chewable tablet/syrup/drops: Doses equivalent to 100 mg of elemental iron daily, up to 300 mg daily.

Iron Polymaltose dosage

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Oral

Iron-deficiency anaemia

Adult: As chewable tablet/syrup/drops: Doses equivalent to 100 mg of elemental iron daily, up to 300 mg daily.

Intramuscular

Iron-deficiency anaemia

Adult: As inj containing 100 mg iron as Iron Polymaltose/2 ml: Admin by ventro-gluteal inj according to Hochstetter method (refer to package insert for details). Total dose of iron needed (mg): Wt (kg) x (normal haemoglobin - actual haemoglobin in g/L) x 0.24 + iron depot. Iron depot calculated as 15 mg/kg up to a wt of about 34 kg, max of 500 mg for body wt ≥34 kg. May give dose as alternate day inj of 2 ml (or 4 ml at longer interval) until total dose is reached. Max single daily dose: >10-45 kg: 2 ml; >45 kg: 4 ml.

Child: As inj containing 100 mg iron as Iron Polymaltose/2 ml: Admin by ventro-gluteal inj according to Hochstetter method (refer to package insert for details).Total dose of iron needed (mg): Wt (kg) x (normal haemoglobin - actual haemoglobin in g/L) x 0.24 + iron depot. Iron depot calculated as 15 mg/kg up to a wt of about 34 kg, max of 500 mg for body wt ≥ 34 kg. Max single daily dose: >10-45 kg: 2 ml; 5-10 kg: 1 ml; infants (up to 5 kg): 0.5 ml.

Incompatibility: Do not mix with acidic substance or substances with a strong reducing effect.

Intravenous

Iron-deficiency anaemia

Adult: As inj containing 100 mg iron as Iron Polymaltose/2 ml: Total dose of iron needed (mg): Wt (kg) x (normal haemoglobin - actual haemoglobin in g/L) x 0.24 + iron depot. Iron depot calculated as 15 mg/kg up to a wt of about 34 kg, max of 500 mg for body wt ≥ 34 kg. Refer to product insert for dosage table. 1st 50 ml to be infused slowly (5-10 drops/minute) and observe patient closely. If well tolerated, increase rate to 30 drops/minute (based on drop volume of 0.067ml).

Child: As inj containing 100 mg iron as Iron Polymaltose/2 ml: Total dose of iron needed (mg): Wt (kg) x (normal haemoglobin - actual haemoglobin in g/L) x 0.24 + iron depot. Iron depot calculated as 15 mg/kg up to a wt of about 34 kg, max of 500 mg for body wt ≥ 34 kg. Refer to product insert for dosage table. 1st 50 ml to be infused slowly (5-10 drops/minute) and observe patient closely. If well tolerated, increase rate to 30 drops/minute (based on drop volume of 0.067ml).

Reconstitution: IV infusion: Total dose to be admin to be added to 500 ml of normal saline (max 2500 mg in 500 ml).

Incompatibility: Do not mix with acidic substance or substances with a strong reducing effect.

Iron Polymaltose interactions

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Concurrent use with psychotropic drugs may worsen constipation. Increased systemic side effects with concomitant ACE inhibitors and parenteral iron admin.

Iron Polymaltose side effects

GI irritation, epigastric pain, stomach cramping, constipation, nausea, vomiting, diarrhoea, dark stools, heart burn, discoloured urine, teeth staining. IM: pain at inj site, abdominal pain at lower quadrant and local inflammation with inguinal lymphadenopathy. IV: Joint and muscle pain, bronchospasm, hypotension, tachycardia, flushing, sweating, dizziness.

Potentially Fatal:

Parenteral: Anaphylactoid reactions, circulatory collapse.

Iron Polymaltose contraindications

Hypersensitivity or intolerance to iron and overloading of iron in the body. Anaemia not caused by iron deficiency. Disturbances in iron utilisation, thalassemia. Patients receiving repeated blood transfusion.

Parenteral: Iron overload, Ostler-Rendu-Weber syndrome, chronic polyarthritis, bronchial asthma, inflammation or infection of kidney or liver, uncontrolled hyperparathyroidism, decompensated liver cirrhosis. Pregnancy (1st trimester).



Active ingredient matches for Iron Polymaltose:

Iron Polymaltose


List of Iron Polymaltose substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Ferrum Hausmann 100 mg x 500's (Vifor)
Ferrum Hausmann 50 mg/1 mL x 30 mL (Vifor)
Ferrum Hausmann 50 mg/5 mL x 150 mL (Vifor)
Ferrum Hausmann 100 mg/2 mL x 5's (Vifor)
Ferrum Hausmann 50 mg/5 mL x 150 mL x 1's (Vifor)$ 18.00
Ferrum Hausmann 50 mg/1 mL x 30 mL x 1's (Vifor)$ 14.30
Ferrum Hausmann chewable tab 100 mg 30's (Vifor)
Ferrum Hausmann inj 100 mg/2 mL 5 x 1's (Vifor)
Ferrum Hausmann oral drops 50 mg/mL 30 mL x 1's (Vifor)
Ferrum Hausmann syr 50 mg/5 mL 150 mL x 1's (Vifor)
Injectable; Injection; Iron / Ferrous Polymaltose; Iron / Iron Sucrose 50 mg / ml (Lek)
Syrup; Oral; Iron / Ferrous Polymaltose; Iron / Iron Sucrose 50 mg / 5 ml (Lek)
Tablet, Chewable; Oral; Iron / Ferrous Polymaltose; Iron / Iron Sucrose 100 mg (Lek)
Ferrum Lek 100mg - 30 Tablets (Lek)$ 16.70
Ferrum Lek 100mg/2ml - 5 Vial (Lek)$ 19.80
POLYFEX syr 50 mg x 5 mL x 200ml (Olcare (Excare))$ 0.90
Rigovit Powd Protein 48% 15 g, carbohydrates 82 g, vitamin A5333 IU, vitamin B1 3.3 mg, vitamin B2 4.5 mg, vitamin B61.6 mg, vitamin B12 1.7 mcg, vitamin C 83 mg, vitamin D3 83mg, vitamin E 17 mg, calciumpantothenate 3.3 mg, coppersulphate 1.6 mg, dicalciump$ 1.69
Rigovit Powd Protein 48% 15 g, carbohydrates 82 g, vitamin A5333 IU, vitamin B1 3.3 mg, vitamin B2 4.5 mg, vitamin B61.6 mg, vitamin B12 1.7 mcg, vitamin C 83 mg, vitamin D3 83mg, vitamin E 17 mg, calciumpantothenate 3.3 mg, coppersulphate 1.6 mg, dicalciump$ 1.69
Rigovit Powd Protein 48% 15 g, carbohydrates 82 g, vitamin A5333 IU, vitamin B1 3.3 mg, vitamin B2 4.5 mg, vitamin B61.6 mg, vitamin B12 1.7 mcg, vitamin C 83 mg, vitamin D3 83mg, vitamin E 17 mg, calciumpantothenate 3.3 mg, coppersulphate 1.6 mg, dicalciump$ 1.69
Rigovit Powd Protein 48% 15 g, carbohydrates 82 g, vitamin A5333 IU, vitamin B1 3.3 mg, vitamin B2 4.5 mg, vitamin B61.6 mg, vitamin B12 1.7 mcg, vitamin C 83 mg, vitamin D3 83mg, vitamin E 17 mg, calciumpantothenate 3.3 mg, coppersulphate 1.6 mg, dicalciump$ 1.69
Rigovit Powd Protein 48% 15 g, carbohydrates 82 g, vitamin A5333 IU, vitamin B1 3.3 mg, vitamin B2 4.5 mg, vitamin B61.6 mg, vitamin B12 1.7 mcg, vitamin C 83 mg, vitamin D3 83mg, vitamin E 17 mg, calciumpantothenate 3.3 mg, coppersulphate 1.6 mg, dicalciump$ 1.69
Rigovit Powd Protein 48% 15 g, carbohydrates 82 g, vitamin A5333 IU, vitamin B1 3.3 mg, vitamin B2 4.5 mg, vitamin B61.6 mg, vitamin B12 1.7 mcg, vitamin C 83 mg, vitamin D3 83mg, vitamin E 17 mg, calciumpantothenate 3.3 mg, coppersulphate 1.6 mg, dicalciump$ 1.69
Solufer Iron 33 mg, folic acid 1.5 mg, cyanocobalamin 15 mcg TAB / 10 (Alkem)$ 0.61
10's (Alkem)$ 0.61
SOLUFER tab 10's (Alkem)$ 0.61
SUFE syr 50 mg x 5 mL x 200ml (Olcare)$ 0.90
Trifer Dps 50mg x 1mL DPS / 15ml (Apex)$ 0.39
TRIFER DPS oral drops 50 mg x 1 mL x 15ml (Apex)$ 0.39
Trifer SYR 50mg x 5mL SYR / 150ml (Apex)$ 0.70
TRIFER SYR syr 50 mg x 5 mL x 150ml (Apex)$ 0.70

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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