What is Lidocaina 2% Epinefrina Normon?
Numbing the skin before you have certain medical procedures (eg, injections, minor skin surgery) in the treated area.
Lidocaina 2% Epinefrina Normon iontophoretic patch is a local anesthetic. It works by stopping nerves from transmitting painful impulses to the brain.
Lidocaina 2% Epinefrina Normon indications
Production of local or regional anaesth by infiltration techniques; IV regional anaesth, by peripheral nerve block techniques eg intercostal blocks; major plexus blocks eg brachial plexus blocks & by epidural & subarachnoid blocks. As Spray: Surface anaesth: In dentistry Otorhinolaryngology for maxillary sinus Paracentesis During delivery Introduction of instruments & catheters into the resp & digestive tract Laryngeal & tracheal procedures As Gel: As a surface anaesth & lubricant for the male & female urethra during cystoscopy, catheterisation, exploration by sound & other endourethral procedures, nasal & pharyngeal cavities in endoscopic procedures eg gastroscopy & bronchoscopy, during proctoscopy & rectoscopy & tracheal intubation. Symptomatic treatment of pain in connection w/ cystitis & urethritis. As Rectal Cream or suppositories for hemorrhoids
How should I use Lidocaina 2% Epinefrina Normon?
Use Lidocaina 2% Epinefrina Normon iontophoretic patch as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Lidocaina 2% Epinefrina Normon iontophoretic patch is usually applied at your doctor's office, hospital, or clinic. If you will be using Lidocaina 2% Epinefrina Normon iontophoretic patch at home, a health care provider will teach you how to use it. Be sure you understand how to use Lidocaina 2% Epinefrina Normon iontophoretic patch. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
- Lidocaina 2% Epinefrina Normon iontophoretic patch is only to be used on intact, clean, dry skin, Do not apply Lidocaina 2% Epinefrina Normon iontophoretic patch to broken, damaged, inflamed, or hairy skin.
- If you miss a dose of Lidocaina 2% Epinefrina Normon iontophoretic patch, contact your doctor right away.
Ask your health care provider any questions you may have about how to use Lidocaina 2% Epinefrina Normon iontophoretic patch.
Lidocaina 2% Epinefrina Normon description
Lidocaina 2% Epinefrina Normon/ Adrenaline is sterile, isotonic, and in addition, contains adrenaline acid tartrate and sodium metabisulfite 0.5 mg/mL as antioxidant. It contains no antimicrobial agent and should be used only once and any residue be discarded.
Lidocaina 2% Epinefrina Normon/ Adrenaline has a pH of approximately 3-4.5.
The chemical abstracts service (CAS) number for lignocaine HCl [Australian approved name (AAN)], is 6108-05-0 and anhydrous lignocaine HCl is 73-78-9. The chemical name for lignocaine HCl is 2-Diethylaminoaceto-2'6'-xylidide HCl. The CAS number for adrenaline is 51-43-4. The chemical name for adrenaline is (R)-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol. The AAN is adrenaline.
Lignocaine base has a pKa of 7.85 (25°C), an oil/water coefficient of 2.9 and a molecular weight of 234.3.
Lignocaine is classed as a membrane-stabilising agent and is a local anaesthetic of the amide-type. It is extremely stable.
Lidocaina 2% Epinefrina Normon dosage
The lowest dosage and volume that results in effective anaesthesia should be used and should be based on the status of the patient and the type of regional anaesthesia intended. Lidocaina 2% Epinefrina Normon/ Adrenaline contains no antimicrobial agent and should be used only once and any residue discarded.
Lignocaine should be administered with great caution to patients with impaired cardiovascular function as they may be less able to compensate for functional changes associated with the prolongation of AV conduction produced by these drugs.
Adults: See table.
Recommended Doses: The previously suggested concentrations and volumes serve only as a guide. Toxic doses vary widely between patients and toxic effects may occur after any local anaesthetic procedure.
Careful observation of the patient must therefore be maintained. It is recommended that the dose of lignocaine at any one time should not exceed 7 mg/kg. However, the dose administered must be tailored to the individual patient and procedure, and the maximum doses here quoted should be used as a guide only.
Hypotension: During thoracic, lumbar and caudal epidural anaesthesia, a marked fall in blood pressure and/or intercostal paralysis may be seen, possibly due to the use of excessive doses, improper positioning of the patient or accidental disposition of the anaesthetic within the subarachnoid space. Hypotension and bradycardia may occur as a result of sympathetic blockade.
Test Dose: For epidural anaesthesia, a 3-5 mL test dose of a local anaesthetic solution preferably containing up to 15 mcg of adrenaline (eg, 3 mL of Xylocaine 2% with adrenaline 1:200,000) should be administered.
Verbal contact and repeated monitoring of heart rate and blood pressure should be maintained for 5 min after the test dose, after which, in the absence of signs of subarachnoid or intravascular injection, the main dose may be administered.
Use of a test dose containing adrenaline may have further advantages in that an intravascular injection of adrenaline will be quickly recognised by an increase in heart rate, usually within about 40 sec. To detect this, the heart rate and rhythm should be monitored with an electrocardiogram.
Prior to administration of the total dose, aspiration should be repeated. The main dose should be injected slowly, with continual assessment of the patient. If toxic symptoms or signs occur, the injection should be stopped immediately.
Children: A reduced dosage based on bodyweight or surface area should be used. The dosage should be calculated for each patient individually and modified in accordance with the physician's experience and knowledge of the patient.
In order to minimise the possibility of toxic effects, the use of Xylocaine 0.5% or 1% solutions is recommended for most anaesthetic procedures involving paediatric patients.
In children, early signs of local anaesthetic toxicity may be difficult to detect in cases where the block is given during general anaesthesia.
Elderly: A reduction in dosage may be necessary for elderly patients especially those with compromised cardiovascular and/or hepatic function.
In epidural anaesthesia, a smaller dose may provide adequate anaesthesia.
Impaired Hepatic Function: Although lignocaine is metabolised by the liver, dosage reduction for local anaesthesia is probably not warranted. However, caution should be exercised with repeated doses.
Impaired Renal Function: Impairment of renal function is unlikely to affect lignocaine clearance in the short-term (24 hrs). However, toxicity due to accumulation may develop with prolonged or repeated administration.
Lidocaina 2% Epinefrina Normon interactions
Lidocaina 2% Epinefrina Normon should be used cautiously in patients with hyperthyroidism, hypertension and cardiac arrhythmias. All vasopressors should be used cautiously in patients taking monoamine oxidase (MAO) inhibitors.
Lidocaina 2% Epinefrina Normon should not be administered concomitantly with other sympathomimetic drugs (such as isoproterenol) because of possible additive effects and increased toxicity.
Combined effects may induce serious cardiac arrhythmias. They may be administered alternately when the preceding effect of other such drug has subsided.
Administration of Lidocaina 2% Epinefrina Normon to patients receiving cyclopropane or halogenated hydrocarbon general anesthetics such as halothane which sensitize the myocardium, may induce cardiac arrhythmia.. When encountered, such arrhythmias may respond to administration of a beta-adrenergic blocking drug. Lidocaina 2% Epinefrina Normon also should be used cautiously with other drugs (e.g., digitalis, glycosides) that sensitize the myocardium to the actions of sympathomimetic drugs.
Diuretic agents may decrease vascular response to pressor drugs such as Lidocaina 2% Epinefrina Normon.
Lidocaina 2% Epinefrina Normon may antagonize the neuron blockade produced by guanethidine resulting in decreased antihypertensive effect and requiring increased dosage of the latter.
Lidocaina 2% Epinefrina Normon side effects
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What are the possible side effects of Lidocaina 2% Epinefrina Normon?
Get emergency medical help if you have any of these signs of an allergic reaction to lorazepam: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
confusion, depressed mood, thoughts of suicide or hurting yourself;
hyperactivity, agitation, hostility;
hallucinations; or
feeling light-headed, fainting.
Less serious lorazepam side effects may include:
drowsiness, dizziness, tiredness;
blurred vision;
sleep problems (insomnia);
muscle weakness, lack of balance or coordination;
amnesia or forgetfulness, trouble concentrating;
nausea, vomiting, constipation;
appetite changes; or
skin rash.
Lidocaina 2% Epinefrina Normon contraindications
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What is the most important information I should know about Lidocaina 2% Epinefrina Normon?
Allergy or hypersensitivity to amide-type local anaesthetics, sodium metabisulfite or to any excipients of Lidocaina 2% Epinefrina Normon/ Adrenaline. Detection of suspected hypersensitivity by skin testing is of limited value.
Local anaesthetics are contraindicated for epidural and spinal anaesthesia in patients with uncorrected hypotension or coagulation disorders or in patients receiving anticoagulation treatment.
Local anaesthetic techniques must not be used when there is inflammation and/or sepsis in the region of the proposed injection and/or in the presence of septicaemia.
General contraindications related to epidural anaesthesia, regardless of the local anaesthetic used, should be taken into account.
Adrenaline is contraindicated in conditions where the production or exacerbation of tachycardia may prove fatal eg, thyrotoxicosis or severe heart disease, or in obstetrics when maternal blood pressure exceeds 130/80 mmHg.
Solutions with adrenaline must not be used for local analgesia in parts of the body with compromised blood supply or supplied by end arteries eg, fingers, toes, nose, ears or penis. There is a possibility of producing arterial vasoconstriction and subsequent ischaemic gangrene distal to the site of injection.
Solutions with adrenaline must not be used for IV regional techniques.
Solutions with adrenaline should not be used in patients with known sensitivity to sympathomimetic amines.
Solutions with adrenaline should not be used in most patients with cerebral arteriosclerosis.
Active ingredient matches for Lidocaina 2% Epinefrina Normon:
Epinephrine/Lidocaine in Spain.
List of Lidocaina 2% Epinefrina Normon substitutes (brand and generic names) | Sort by popularity |
Unit description / dosage (Manufacturer) | Price, USD |
Lidocaina/Epinefrina (Spain) | |
Lidocaine 1% and Epinephrine 1:100,000 | |
Injectable; Injection; Epinephrine 0.01 mg; Lidocaine Hydrochloride 10 mg / ml | |
Lidocaine 2% and Epinephrine (Canada) | |
Injectable; Injection; Epinephrine Bitartrate 0.01 mg; Lidocaine Hydrochloride 20.4 mg / ml | |
Injectable; Injection; Epinephrine 0.01 mg; Lidocaine Hydrochloride 20 mg / ml | |
Lidocaine 2% and Epinephrine 1:100,000 | |
Injectable; Injection; Epinephrine 0.01 mg; Lidocaine Hydrochloride 20 mg / ml | |
Injectable; Injection; Epinephrine Bitartrate 0.0204 mg; Lidocaine Hydrochloride 20 mg / ml | |
Liquid; Dental; Subcutaneous; Epinephrine 0.01 mg; Lidocaine Hydrochloride 20 mg / ml | |
Injectable; Injection; Epinephrine 0.02 mg; Lidocaine Hydrochloride 20 mg / ml | |
Solution; Dental; Epinephrine Bitartrate 0.01 mg; Lidocaine Hydrochloride 20 mg / ml | |
Lidocaine 2% and Epinephrine 1:100000 | |
Injectable; Injection; Epinephrine 0.01 mg; Lidocaine Hydrochloride 20 mg / ml | |
Lidocaine 2% and Epinephrine 1:50,000 | |
Solution; Dental; Epinephrine Bitartrate 0.02 mg; Lidocaine Hydrochloride 20 mg / ml | |
Injectable; Injection; Epinephrine 0.01 mg; Lidocaine Hydrochloride 20 mg / ml | |
Injectable; Injection; Epinephrine 0.02 mg; Lidocaine Hydrochloride 20 mg / ml | |
Liquid; Dental; Subcutaneous; Epinephrine 0.02 mg; Lidocaine Hydrochloride 20 mg / ml | |
Injectable; Injection; Epinephrine Bitartrate 0.0407 mg; Lidocaine Hydrochloride 20 mg / ml | |
Lidocaine 2% E-80 (Turkey) | |
Lidocaine 2% Epinephrine Normon (Vietnam) | |
Lidocaine 2% Epinephrine Normon 10 tube 1.8 mL | |
Lidocaine 2% Medis avec Adrenaline (Tunisia) | |
Lidocaine 4% voor honden en katten (Netherlands) | |
Lidocaïne Adrénaline Aguettant (France) | |
Lidocaine Adrenaline Aguettant (Tunisia) | |
Lidocaine and Epinephrine Abbott (United States) | |
Lidocaine HCI and Epinephrine Eastman (United States) | |
Lidocaine HCL 2% and Epinephrine 1:100000 (Israel) | |
Lidocaine HCl and Epinephrin (Israel) | |
Lidocaine HCl and Epinephrin Alveda (Canada) | |
Lidocaine Hydrochloride 1% and Epinephrine (Canada) | |
Lidocaine Hydrochloride 2% and Epinephrine (Canada) | |
Lidocaine Hydrochloride and Epinephrine (Bahrain, Canada) | |
Lidocaine Hydrochloride and Epinephrine Eastman Kodak (United States) | |
Lidocaine Hydrochloride and Epinephrine Hospira (United States) | |
Lidocaine with Epinephrine (Georgia) | |
Lidocaine; Adrenaline | |
Injectable; Injection; Epinephrine Tartrate 10 mcg; Lidocaine Hydrochloride Dihydrate 10 mg / ml | |
Injectable; Injection; Epinephrine Tartrate 22.25 mcg; Lidocaine Hydrochloride Dihydrate 20 mg / ml | |
Lidocaine; Epinephrine | |
Injectable; Injection; Epinephrine 0.01 mg; Lidocaine Hydrochloride 20 mg / ml | |
Injectable; Injection; Epinephrine 0.01 mg; Lidocaine Hydrochloride 10 mg / ml | |
Injectable; Injection; Epinephrine 0.02 mg; Lidocaine Hydrochloride 20 mg / ml | |
Solution; Iontophoresis; 0.01 mg; 2% | |
Injectable; Injection; Epinephrine 0.005 mg; Lidocaine Hydrochloride 0.5% | |
Injectable; Injection; Epinephrine 0.005 mg; Lidocaine Hydrochloride 1% | |
Injectable; Injection; Epinephrine 0.005 mg; Lidocaine Hydrochloride 1.5% | |
Injectable; Injection; Epinephrine 0.005 mg; Lidocaine Hydrochloride 2% | |
See 287 substitutes for Lidocaina 2% Epinefrina Normon |
References
- DailyMed. "LIDOCAINE; TETRACAINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "EPINEPHRINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "epinephrine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology