Mephenoxalone Uses

Rating: 5 - 4 review(s)
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Mephenoxalone indications

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Bursitis,Tendinitis,Pain and inflammation associated with musculoskeletal and joint disorders,Acute gout,Dysmenorrhoea,Migraine,Postoperative pain,Prophylaxis of postoperative pain,Strains,Tendinitis,Renal colic,Prophylaxis of intra-operative miosis,Post-photorefractive keratectomy pain,Seasonal allergic conjunctivitis,Control of inflammation after argon laser trabeculoplasty,Inflammation and discomfort after strabismus surgery,Pain after accidental trauma,Local symptomatic relief of pain and inflammation,Osteoarthritis.

Mephenoxalone dosage

Oral

Muscle spasms

Adult: 200-400 mg tid.

Mephenoxalone interactions

Not to be given IV to patients who are receiving other NSAIDs or anticoagulants including low dose heparin. Renal function may be worsened when used with ciclosporin or triamterene. Altered absorption when given with sucralfate, colestyramine or colestipol. Ophthalmic application of diclofenac may reduce the efficacy of ophthalmic acetylcholine and carbachol. Increased risk of GI ulceration and bleeding when used with corticosteroids, aspirin or anticoagulants.

Potentially Fatal: Increases blood levels of digoxin, lithium and methotrexate. Potentiate potassium-sparing diuretics.

Food Interaction

Slow absorption of enteric-coated tab when given with food.

Mephenoxalone side effects

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Central Nervous System

Drowsiness, ataxia, dizziness, slurred speech, headache, vertigo,weakness, paresthesias, impairment of visual accommodation,euphoria, overstimulation, paradoxical excitement, fast EEG activity.

Gastrointestinal

Nausea, vomiting, diarrhea.

Cardiovascular

Palpitation, tachycardia, various forms of arrhythmia, transient ECGchanges, syncope; also hypotensive crisis (including one fatal case).

Allergic or Idiosyncratic

Allergic or idiosyncratic reactions are usually seen within the period ofthe first to fourth dose in patients having had no previous contact withthe drug. Milder reactions are characterized by an itchy, urticarial, orerythematous maculopapular rash which may be generalized orconfined to the groin. Other reactions have included leukopenia, acutenonthrombocytopenic purpura, petechiae, ecchymoses, eosinophilia,peripheral edema, adenopathy, fever, fixed drug eruption with crossreaction to carisoprodol, and cross sensitivity betweenMeprobamate/mebutamate and Meprobamate/carbromal.

More severe hypersensitivity reactions, rarely reported, includehyperpyrexia, chills, angioneurotic edema, bronchospasm, oliguriaand anuria. Also, anaphylaxis, erythema multiforme, exfoliativedermatitis, stomatitis, proctitis, Stevens-Johnson syndrome andbullous dermatitis, including one fatal case of the latter followingadministration of Meprobamate in combination with prednisolone.

In case of allergic or idiosyncratic reactions to Meprobamate,discontinue the drug and initiate appropriate symptomatic therapy,which may include epinephrine, antihistamines, and in severe cases,corticosteroids. In evaluating possible allergic reactions, also considerallergy to excipients.

Hematologic

. Agranulocytosis and aplasticanemia have been reported. These cases rarely were fatal. Rare casesof thrombocytopenic purpura have been reported.

Other

Exacerbation of porphyric symptoms.

Mephenoxalone contraindications

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Active peptic ulcer; hypersensitivity to diclofenac or other NSAIDs. Treatment of perioperative pain in CABG surgery. 3rd trimester of pregnancy.

Topical: Not to be applied onto damaged or nonintact skin.

Active ingredient matches for Mephenoxalone:

Mephenoxalone


Unit description / dosage (Manufacturer)Price, USD
Mephenoxalone 200 mg x 1000's
Mephenoxalone 200 mg x 100 x 10's

List of Mephenoxalone substitutes (brand and generic names):

Doflex 25mg Injection (Jagsonpal Pharmaceuticals Ltd)$ 0.01
Doflex 50mg Injection (Jagsonpal Pharmaceuticals Ltd)$ 0.01
Doflex 50mg Tablet (Jagsonpal Pharmaceuticals Ltd)$ 0.01
Doflex NA Gel (Jagsonpal Pharmaceuticals Ltd)$ 0.18
Tablet; Oral; Mephenoxalone 200 mg (Ilsan)
Dorsiflex 200 mg x 1000's (Ilsan)
Dorsiflex 200 mg x 2 Blister x 10 Tablet (Ilsan)
Dorsiflex 200 mg x 100 x 10's (Ilsan)
Losilone 200 mg
Mefno 200 mg
Mefno 200 mg x Blister pk
Melux 200 mg x 1000's
Melux 500 mg x 1000's
Meshin 500 mg
Monphelone 500 mg
Mulaxis 200 mg x 1's
Mulaxis 200 mg x 1000's
Mulaxis 200 mg x 100 x 10's
Muxalon 200 mg x 1000's
Ningist 200 mg
Noxalone 500 mg x 1000's
PWP Tab 200 mg x 1000's
Sudorxan 200 mg
Suflex 200 mg x 1000's
Surmax 500 mg
U-Sulax 200 mg
U-Sulax 200 mg x 100 x 10's

Reviews

The results of a survey conducted on ndrugs.com for Mephenoxalone are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Mephenoxalone. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

1 consumer reported useful

Was the Mephenoxalone drug useful in terms of decreasing the symptom or the disease?
According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
Users%
Useful1
100.0%


1 consumer reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Mephenoxalone drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users%
Not expensive1
100.0%


1 consumer reported time for results

To what extent do I have to use Mephenoxalone before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 2 weeks and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Mephenoxalone. To get the time effectiveness of using Mephenoxalone drug by other patients, please click here.
Users%
2 weeks1
100.0%


5 consumers reported age

Users%
16-292
40.0%
6-151
20.0%
46-601
20.0%
> 601
20.0%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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