What is Monovent?
Monovent injection is used to prevent bronchospasm in patients 12 years of age and older with asthma, bronchitis, emphysema, and other lung diseases.
Monovent belongs to the family of medicines known as bronchodilators. Bronchodilators are medicines that relax the muscles in the bronchial tubes (air passages) of the lungs. They relieve cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes.
Monovent is available only with your doctor's prescription.
Monovent indications
Oral
Acute bronchospasm
Adult: Initially, 2.5 mg or 3 mg tid, up to 5 mg tid as necessary. As modified-release tab: 5 mg or 7.5 mg bid.
Child: Inhalation Acute bronchospasm Adult: As metered-dose powd inhaler: 250-500 mcg as required. Max: 2,000 mcg daily. Severe bronchospasm Adult: 250-500 mcg up to 4 times daily by SC, IM or IV inj, or by IV infusion as a soln containing 3-5 mcg/mL at a rate of 0.5-1 mL/min. Child: Reconstitution: Add 10 mL of Monovent soln for inj to 40 mL of dextrose 5% if using a syringe pump or to 490 mL of dextrose 5% if syringe pump is not available. Uncomplicated premature labour Adult: To arrest labour between 22-37 wk of gestation: Initially, 5 mcg/min, w/ increments of 2.5 mcg/min at 20 min intervals until contractions stop. Max: 20 mcg/min. Continue for 1 hr after contractions have ceased, then decrease by 2.5 mcg/min every 20 min to lowest dose that maintains suppression. Max duration: 48 hr. Reconstitution: Add 10 mL of Monovent soln for inj to 40 mL of dextrose 5% if using a syringe pump or to 490 mL of dextrose 5% if syringe pump is not available. Inhalation Severe bronchospasm Adult: As 1% nebuliser soln: 2.5-10 mg 2-4 times daily. Child: <25 kg: 2-5 mg 2-4 times daily; ≥25 kg: 5 mg 2-4 times daily. Use Monovent as directed by your doctor. Check the label on the medicine for exact dosing instructions. Ask your health care provider any questions you may have about how to use Monovent. Asthma/Bronchospasm: Prevention and reversal of bronchospasm in patients ≥12 years of age with asthma and reversible bronchospasm associated with bronchitis and emphysema Data from a limited number of patients suggests that Monovent may be beneficial for the management of extravasation of sympathomimetic vasoconstrictors. Monovent turbuhaler is a breath-activated, multiple-dose powder inhaler free from propellant, lubricant, preservative, carrier substances or other additives. Monovent injection also contains the following inactive ingredients: Sodium chloride, HCl (for pH adjustment) and water for injections. Monovent sulphate is 2-(tert-butylamino)-1-(3,5-dihydroxyphenyl)ethanol sulphate. Tablet: Adults: Usual Dose: 1-2 tablets. Children 12-15 years: 1 tablet. All doses to be taken 2-3 times daily. To be administered at approximately 6-hr intervals. In most patients, the optimum single dose is 2 tablets. In patients unusually sensitive to sympathomimetic amines, initiate treatment with 1 tablet 3 times a day. If adequate bronchodilation is not obtained, the dose may be increased to 2 tablets. Syrup: Adults and Children >15 years: 10-15 mL (2-3 tsp). Children 7-15 years: 5-10 mL (1-2 tsp); 3-7 years: 2.5-5 mL (½-1 tsp); <3 years: Not recommended. All doses to be taken 3 times a day. Nebulizing Solution: Monovent nebulizing solution is used with dilution. Inhale 1 mL of solution containing Monovent 2.5 mg every 6 hrs (or 4 times in 24-hr period). If the entire dose is not inhaled at 1 occasion, the solution is stable for 24 hrs in the reservoir of the nebulizer. Note: The patient's inhalation technique should be checked regularly and the optimal dose of Monovent should be adjusted for each nebulizer. If the effect of the inhalation is reduced, the patient should seek medical care. Nonselective blocking agents may partly or totally inhibit the effect of β-stimulants. Directions for Use: 1. Pipette 1 mL of Monovent nebulizing solution from the bottle by using a calibrated medicine dropper provided in the pack, equivalent to Monovent 2.5 mg. 2. Drop the solution into an electric nebulizer and dilute it with normal saline solution 2 mL and start inhalation. 3. Repeat the same procedure every 6 hrs or 4 times in 24-hr period. See also: Drug Interactions The concomitant use of Monovent with other sympathomimetic agents is not recommended, since the combined effect on the cardiovascular system may be deleterious to the patient Monoamine Oxidase Inhibitors or Tricyclic Antidepressants: Monovent should be administered with extreme caution to patients being treated with monoamine oxidase inhibitors or tricyclic antidepressants, or within 2 weeks of discontinuation of such agents, since the action of Monovent on the vascular system may be potentiated Beta-Blockers Beta-adrenergic receptor blocking agents not only block the pulmonary effect of beta-agonists, such as Monovent, but may produce severe bronchospasm in asthmatic patients. Therefore, patients with asthma should not normally be treated with beta-blockers. However, under certain circumstances, e.g., as prophylaxis after myocardial infarction, there may be no acceptable alternatives to the use of beta-adrenergic blocking agents in patients with asthma. In this setting, cardioselective beta-blockers could be considered, although they should be administered with caution Diuretics The ECG changes and/or hypokalemia that may result from the administration of nonpotassium-sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. Although the clinical significance of these effects is not known, caution is advised in the coadministration of beta-agonists with nonpotassium-sparing diuretics. See also: Applies to Monovent: oral elixir, oral tablet Other dosage forms: In addition to its needed effects, some unwanted effects may be caused by Monovent (the active ingredient contained in Monovent). In the event that any of these side effects do occur, they may require medical attention. You should check with your doctor immediately if any of these side effects occur when taking Monovent: More common: If any of the following symptoms of overdose occur while taking Monovent, get emergency help immediately: Symptoms of overdose: Some of the side effects that can occur with Monovent may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional: More common: See also: Monovent has not been approved for and should not be used for prolonged tocolysis (beyond 48-72 hours). In particular, Monovent should not be used for maintenance tocolysis in the outpatient or home setting. Monovent injection is contraindicated in patients known to be hypersensitive to sympathomimetic amines or any component of this drug product.Parenteral
Intravenous
How should I use Monovent?
Uses of Monovent in details
Use: Labeled Indications
Off Label Uses
Extravasation management, sympathomimetic vasoconstrictors
Monovent description
Monovent dosage
Monovent interactions
What other drugs will affect Monovent?
Monovent side effects
What are the possible side effects of Monovent?
Major Side Effects
Less common:
Rare
Minor Side Effects
Less common:
Rare
Monovent contraindications
What is the most important information I should know about Monovent?
Active ingredient matches for Monovent:
Terbutaline in United Kingdom.
Terbutaline sulfate in United Kingdom.
Unit description / dosage (Manufacturer) | Price, USD |
MONOVENT 5MG/75MG TABLET 1 strip / 10 tablets each (Obsurge Biotech Ltd) | $ 0.69 |
Monovent 5 mg/75 mg Tablet (Obsurge Biotech Ltd) | $ 0.07 |
List of Monovent substitutes (brand and generic names): | |
MONLEVO-A (India) | |
Monlevo-A Levocetirizine 5 mg, Ambroxol60 mg. TAB / 10 | $ 0.46 |
Mucosolvin SYR (India) | |
Mucosolvin SYR Terbutaline 1.25 mg, guaiphenesin 100 mg, ambroxol30 mg, menthol 2.5 mg/5 mL SYR / 100ml (IPCA) | $ 0.64 |
Mucosolvin SYR Terbutaline 1.25 mg, guaiphenesin 100 mg, ambroxol30 mg, menthol 2.5 mg/5 mL SYR / 60ml (IPCA) | $ 0.45 |
MUCOSOLVIN SYR syr 100ml (IPCA) | $ 0.64 |
MUCOSOLVIN SYR syr 60ml (IPCA) | $ 0.45 |
Nairet (Indonesia) | |
Nairet 2.5 mg x 10 x 10's (Otto) | $ 8.68 |
Nairet 1.5 mg/5 mL x 60 mL x 1's (Otto) | $ 1.98 |
Nairet 0.5 mg/1 mL x 5's (Otto) | $ 6.20 |
Nairet 0.5 mg/1 mL x 5 tube x 1 mL (Otto) | |
Neosma (Indonesia) | |
Neosma 2.5 mg x 10 x 10's (Ifars) | |
Neoterb (Oman) | |
Nortol (Venezuela) | |
NUCEZ-AM (India) | |
NUCEZ-AM tab 10's (Little Greave) | $ 0.90 |
NUTROL AX | |
NUTROL AX SYRUP 1 bottle / 100 ML syrup each (Algen Healthcare Pvt Ltd) | $ 0.75 |
Nutrol AX Syrup (Algen Healthcare Pvt Ltd) | $ 0.89 |
P-Canyl (Thailand) | |
P-Canyl 2.5 mg x 1, 000's (Osoth Interlab) | |
P-Canyl tab 2.5 mg 1000's (Osoth Interlab) | |
Pharmaniaga Terbutaline (Malaysia) | |
Pharmaniaga Terbutaline 2.5 mg x 50 x 10's | |
Pharmaniaga Terbutaline 1.5 mg/5 mL x 1 L | |
Pharmaniaga Terbutaline 2.5 mg/1 mL x 10 mL | |
Pharmaniaga Terbutaline 2.5 mg/1 mL x 20 mL | |
Pharmaniaga Terbutaline 2.5 mg/1 mL x 50 mL | |
Pharmaniaga Terbutaline 10 mg/1 mL x 10 mL | |
Pharmaniaga Terbutaline 10 mg/1 mL x 50 mL | |
PRIMECET AM | |
PRIMECET AM SYRUP 1 bottle / 60 ML syrup each (Ind Swift Laboratories Ltd) | $ 0.18 |
Proasma-T (Thailand) | |
Proasma-T 2.5 mg x 1, 000's (Medicine products) | |
Proasma-T 1.5 mg/5 mL x 60 mL (Medicine products) | |
Proasma-T 1.5 mg/5 mL x 1 gal (Medicine products) | |
Pulmobron (Indonesia) | |
Pulmobron 2.5 mg x 50's (Mugi) | $ 3.10 |
Pulmobron 1.5 mg/5 mL x 60 mL x 1's (Mugi) | $ 1.43 |
Pulmonyl (Philippines) | |
Pulmonyl 2.5 mg/1 mL x 2 mL x 30's (Euro-med) | $ 0.58 |
Pulmonyl 500 mcg/1 mL x 1 mL (Euro-med) | $ 2.74 |
Pulmoxcel (Philippines) | |
Pulmoxcel 2 mg x 100's (GXI) | $ 0.05 |
Pulmoxcel 1.5 mg/5 mL x 60 mL (GXI) | $ 1.16 |
Pulmoxcel 2.5 mg/1 mL x 15 mL (GXI) | $ 1.36 |
Pulmoxcel 2.5 mg/1 mL x 30 mL (GXI) | $ 2.31 |
Pulmoxcel nebulizing soln 2.5 mg/mL 15 mL x 1's (GXI) | $ 1.36 |
Pulmoxcel nebulizing soln 2.5 mg/mL 30 mL x 1's (GXI) | $ 2.31 |
Pulmoxcel syr 1.5 mg/5 mL 60 mL x 1's (GXI) | $ 1.16 |
Pulmoxcel tab 2 mg 100's (GXI) | $ 0.05 |
RELENT OD | |
RELENT OD 5 MG/75 MG CAPSULE 1 strip / 10 capsules each (Dr Reddy's Laboratories Ltd) | $ 0.70 |
Relivan (Indonesia) | |
Relivan 0.5 mg/1 mL x 1 mL x 6's (Novell) | $ 2.30 |
See 711 substitutes for Monovent |
References
- DailyMed. "TERBUTALINE SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "terbutaline". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- PubChem. "ambroxol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Monovent are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Monovent. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yet1 consumer reported age
Users | % | ||
---|---|---|---|
16-29 | 1 | 100.0% |
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Information checked by Dr. Sachin Kumar, MD Pharmacology