What is Narva SR 1.5 mg retard?
Narva SR 1.5 mg retard belongs to the group of medicines known as diuretics. It is commonly used to treat high blood pressure (hypertension).
High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.
Narva SR 1.5 mg retard is also used to help reduce the amount of water in the body by increasing the flow of urine.
Narva SR 1.5 mg retard is available only with your doctor's prescription.
Narva SR 1.5 mg retard indications
Narva SR 1.5 mg retard (Narva SR 1.5 mg retard) is indicated for the treatment of hypertension, alone or in combination with other antihypertensive drugs.
Narva SR 1.5 mg retard (Narva SR 1.5 mg retard) is also indicated for the treatment of salt and fluid retention associated with congestive heart failure.
Usage in Pregnancy
The routine use of diuretics in an otherwise healthy woman is inappropriate and exposes mother and fetus to unnecessary hazard.
Diuretics do not prevent development of toxemia of pregnancy, and there is no satisfactory evidence that they are useful in the treatment of developed toxemia.
Edema during pregnancy may arise from pathological causes or from the physiologic and mechanical consequences of pregnancy. Narva SR 1.5 mg retard is indicated in pregnancy when edema is due to pathologic causes, just as it is in the absence of pregnancy (however, see PRECAUTIONS below). Dependent edema in pregnancy, resulting from restriction of venous return by the expanded uterus, is properly treated through elevation of the lower extremities and use of support hose; use of diuretics to lower intravascular volume in this case is illogical and unnecessary. There is hypervolemia during normal pregnancy which is not harmful to either the fetus or the mother (in the absence of cardiovascular disease), but which is associated with edema, including generalized edema in the majority of pregnant women. If this edema produces discomfort, increased recumbency will often provide relief. In rare instances, this edema may cause extreme discomfort which is not relieved by rest. In these cases, a short course of diuretics may provide relief and may be appropriate.
How should I use Narva SR 1.5 mg retard?
Use Narva SR 1.5 mg retard as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Narva SR 1.5 mg retard by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
- Narva SR 1.5 mg retard may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.
- If you miss a dose of Narva SR 1.5 mg retard and you are taking 1 dose daily, take the missed dose if you remember the same day. Skip the missed dose if you do not remember until the next day. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Narva SR 1.5 mg retard.
Uses of Narva SR 1.5 mg retard in details
Use: Labeled Indications
Heart failure: Treatment of edema in heart failure
Hypertension: Management of mild to moderate hypertension
Guideline recommendations: The 2017 Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults recommends if monotherapy is warranted, in the absence of comorbidities (eg, cerebrovascular disease, chronic kidney disease, diabetes, heart failure, ischemic heart disease, etc), that thiazide-like diuretics or dihydropyridine calcium channel blockers may be preferred options due to improved cardiovascular endpoints (eg, prevention of heart failure and stroke). ACE inhibitors and ARBs are also acceptable for monotherapy. Combination therapy may be required to achieve blood pressure goals and is initially preferred in patients at high risk (stage 2 hypertension or atherosclerotic cardiovascular disease [ASCVD] risk ≥10%) (ACC/AHA [Whelton 2017]).
Off Label Uses
Calcium nephrolithiasis
Data from a prospective, randomized, study supports the use of Narva SR 1.5 mg retard for the prevention of recurrent calcium nephrolithiasis. Additional trials may be necessary to further define the role of Narva SR 1.5 mg retard in the treatment of this condition.
Based on the American Urologic Association (AUA) guidelines for the medical management of kidney stones, Narva SR 1.5 mg retard is effective and recommended for the prevention of recurrent calcium stones in patients with high or relatively high urine calcium concentrations.
Narva SR 1.5 mg retard description
Narva SR 1.5 mg retard also contains the following excipients: Tablet: Lactose monohydrate 124.5 mg, anhydrous colloidal silica, hypromellose, magnesium stearate, povidone. Film-coating: Glycerol, hypromellose, macrogol 6000, magnesium stearate, titanium dioxide.
Narva SR 1.5 mg retard dosage
Narva SR 1.5 mg retard Dosage
Generic name: Narva SR 1.5 mg retard
Dosage form: Tablets
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Hypertension
The adult starting Narva SR 1.5 mg retard dose for hypertension is 1.25 mg as a single daily dose taken in the morning. If the response to 1.25 mg is not satisfactory after four weeks, the daily dose may be increased to 2.5 mg taken once daily. If the response to 2.5 mg is not satisfactory after four weeks, the daily dose may be increased to 5.0 mg taken once daily, but adding another antihypertensive should be considered.
Edema of Congestive Heart Failure
The adult starting Narva SR 1.5 mg retard dose for edema of congestive heart failure is 2.5 mg as a single daily dose taken in the morning. If the response to 2.5 mg is not satisfactory after one week, the daily dose may be increased to 5.0 mg taken once daily.
If the antihypertensive response to Narva SR 1.5 mg retard is insufficient, Narva SR 1.5 mg retard may be combined with other antihypertensive drugs, with careful monitoring of blood pressure. It is recommended that the usual dose of other agents be reduced by 50% during initial combination therapy. As the blood pressure response becomes evident, further dosage adjustments may be necessary.
In general, doses of 5.0 mg and larger have not appeared to provide additional effects on blood pressure or heart failure, but are associated with a greater degree of hypokalemia. There is minimal clinical trial experience in patients with doses greater than 5.0 mg once a day.
More about Narva SR 1.5 mg retard (Narva SR 1.5 mg retard)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- 0 Reviews - Add your own review/rating
Consumer resources
- Narva SR 1.5 mg retard
- Narva SR 1.5 mg retard (Advanced Reading)
Professional resources
- Narva SR 1.5 mg retard (AHFS Monograph)
- Narva SR 1.5 mg retard (FDA)
Related treatment guides
- Edema
- High Blood Pressure
Narva SR 1.5 mg retard interactions
See also:
What other drugs will affect Narva SR 1.5 mg retard?
Other Antihypertensives
Narva SR 1.5 mg retard (Narva SR 1.5 mg retard) may add to or potentiate the action of other antihypertensive drugs. In limited controlled trials that compared the effect of Narva SR 1.5 mg retard combined with other antihypertensive drugs with the effect of the other drugs administered alone, there was no notable change in the nature or frequency of adverse reactions associated with the combined therapy.
Lithium
Post-Sympathectomy Patient
The antihypertensive effect of the drug may be enhanced in the post-sympathectomized patient.
Norepinephrine
Narva SR 1.5 mg retard, like the thiazides, may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use.
Narva SR 1.5 mg retard side effects
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What are the possible side effects of Narva SR 1.5 mg retard?
Applies to Narva SR 1.5 mg retard: oral tablet
In addition to its needed effects, some unwanted effects may be caused by Narva SR 1.5 mg retard (the active ingredient contained in Narva SR 1.5 mg retard). In the event that any of these side effects do occur, they may require medical attention.
Severity: Moderate
If any of the following side effects occur while taking Narva SR 1.5 mg retard, check with your doctor or nurse as soon as possible:
Signs and symptoms of an imbalance of water or potassium in the body
- Dryness of mouth
- increased thirst
- irregular heartbeat
- mood or mental changes
- muscle cramps or pain
- nausea or vomiting
- unusual tiredness or weakness
- weak pulse
- Skin rash, itching, or hives
Minor Side Effects
Some of the side effects that can occur with Narva SR 1.5 mg retard may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
Less common or rare:
- Diarrhea
- dizziness or lightheadedness, especially when getting up from a lying or sitting position
- headache
- loss of appetite
- trouble in sleeping
- stomach upset
Narva SR 1.5 mg retard contraindications
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What is the most important information I should know about Narva SR 1.5 mg retard?
Hypersensitivity to Narva SR 1.5 mg retard or any component of the formulation or sulfonamide-derived drugs; anuria
Note: Although the FDA approved product labeling states this medication is contraindicated with other sulfonamide-containing drug classes, the scientific basis of this statement has been challenged. See “Warnings/Precautions” for more detail.
Canadian labeling: Additional contraindications (not in US labeling): Severe renal failure (CrCl <30 mL/minute); hepatic encephalopathy; severe hepatic impairment; hypokalemia; concomitant use with antiarrhythmic agents causing torsade de pointes; pregnancy; breast-feeding; hereditary problems of galactose intolerance, glucose-galactose malabsorption, or Lapp lactase deficiency
Active ingredient matches for Narva SR 1.5 mg retard:
Indapamide in Hungary.
List of Narva SR 1.5 mg retard substitutes (brand and generic names) | Sort by popularity |
Unit description / dosage (Manufacturer) | Price, USD |
Narva SR (Hungary) | |
Nashindolen (Japan) | |
Natramid (United Kingdom) | |
NATRIDAC | |
NATRIDAC SR 1.5 MG TABLET 1 strip / 10 tablets each (Zydus Cadila) | $ 0.59 |
Natrilix (Argentina, Australia, Bahrain, Bangladesh, Brazil, Chile, China, Colombia, Costa Rica, Dominican Republic, Egypt, El Salvador, Finland, Germany, Ghana, Guatemala, Honduras, Hong Kong, Iceland, India, Iraq, Ireland, Italy, Jordan, Kuwait, Lebanon, Malaysia, Malta, Mexico, Nicaragua, Nigeria, Oman, Panama, Peru, Philippines, Saudi Arabia, Singapore, South Africa, Sri Lanka, Sudan, Syria, Thailand, United Arab Emirates, United Kingdom, Venezuela, Yemen) | |
Tablet, Film-Coated; Oral; Indapamide Hemihydrate 2.5 mg (Serdia Pharmaceuticals (India) Ltd.) | |
Natrilix 1.5mg SR-TAB / 10 (Serdia Pharmaceuticals (India) Ltd.) | $ 0.95 |
Natrilix 2.5mg TAB / 10 (Serdia Pharmaceuticals (India) Ltd.) | $ 0.94 |
Natrilix 2.5 mg x 30's (Serdia Pharmaceuticals (India) Ltd.) | |
Natrilix SR 1.5 mg x 30's (Serdia Pharmaceuticals (India) Ltd.) | |
Natrilix 2.5 mg x 60's (Serdia Pharmaceuticals (India) Ltd.) | |
Natrilix SR 1.5 mg x 60's (Serdia Pharmaceuticals (India) Ltd.) | |
2.5 mg x 10's (Serdia Pharmaceuticals (India) Ltd.) | $ 0.94 |
1.5 mg x 10's (Serdia Pharmaceuticals (India) Ltd.) | $ 0.95 |
Natrilix 2.5 mg Tablet (Serdia Pharmaceuticals (India) Ltd.) | $ 0.10 |
NATRILIX 2.5 MG TABLET 1 strip / 10 tablets each (Serdia Pharmaceuticals (India) Ltd.) | $ 0.97 |
NATRILIX SR 1.5 MG TABLET 1 strip / 10 tablets each (Serdia Pharmaceuticals (India) Ltd.) | $ 1.18 |
NATRILIX tab 2.5 mg x 10's (Serdia Pharmaceuticals (India) Ltd.) | $ 1.01 |
NATRILIX SR tab 1.5 mg x 10's (Serdia Pharmaceuticals (India) Ltd.) | $ 1.05 |
Natrilix 1.5mg Tablet SR (Serdia Pharmaceuticals (India) Ltd.) | $ 0.12 |
Natrilix 2.5mg Tablet (Serdia Pharmaceuticals (India) Ltd.) | $ 0.11 |
Natrilix 2.5mg Tablets (United Kingdom) | |
Natrilix LP (Italy) | |
Natrilix Retard (Denmark, Sweden) | |
Natrilix SR (Aruba, Australia, Bahamas, Barbados, Bermuda, Cayman Islands, Chile, Costa Rica, Dominican Republic, El Salvador, Germany, Grenada, Guatemala, Guyana, Honduras, Indonesia, Jamaica, Mexico, Nicaragua, Panama, Peru, Saint Lucia, Saint Vincent & The Grenadines, Taiwan, Trinidad & Tobago, Vietnam) | |
Tablet, Prolonged Release; Oral; Indapamide 1.5 mg (Serdia Pharmaceuticals (India) Ltd.) | |
Natrilix SR 1.5 mg x 30's (Serdia Pharmaceuticals (India) Ltd.) | $ 21.56 |
Natrilix SR 1.5 mg x 30's (Serdia Pharmaceuticals (India) Ltd.) | |
Natrilix SR 1.5 mg x 30 Tablet (Serdia Pharmaceuticals (India) Ltd.) | |
Natrilix SR 1.5 mg Tablet (Serdia Pharmaceuticals (India) Ltd.) | $ 0.10 |
Natrilix SR tab 1.5 mg 30's (Serdia Pharmaceuticals (India) Ltd.) | $ 24.04 |
Natrilix SR film-coated tab 1.5 mg 30's (Serdia Pharmaceuticals (India) Ltd.) | |
Natrilix SR coated tab 1.5 mg 10's (Serdia Pharmaceuticals (India) Ltd.) | |
Natrilix SR coated tab 1.5 mg 30's (Serdia Pharmaceuticals (India) Ltd.) | |
NATRITOR | |
NATRITOR 2.5 MG TABLET 1 strip / 10 tablets each (Ipca Laboratories Ltd) | $ 0.36 |
NATRITOR SR 1.5 MG TABLET 1 strip / 10 tablets each (Ipca Laboratories Ltd) | $ 0.48 |
Natritor 1.5mg Tablet SR (Ipca Laboratories Ltd) | $ 0.05 |
Natritor 2.5mg Tablet (Ipca Laboratories Ltd) | $ 0.04 |
Natritor SR | |
Natritor SR 1.5 mg Tablet (IPCA Laboratories Ltd.) | $ 0.05 |
Natritor SR 2.5 mg Tablet (IPCA Laboratories Ltd.) | $ 0.04 |
Natrix (Japan, South Korea) | |
Natrix SR (South Korea) | |
Neopamid (Bulgaria) | |
Neopamid SR (Bulgaria) | |
See 704 substitutes for Narva SR 1.5 mg retard |
References
- DailyMed. "INDAPAMIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "indapamide". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "indapamide". http://www.drugbank.ca/drugs/DB00808 (accessed September 17, 2018).
Reviews
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Information checked by Dr. Sachin Kumar, MD Pharmacology