What is Palipase MT 20?
Improving food digestion in patients who cannot digest food properly because they have a pancreas problem (exocrine pancreatic insufficiency) caused by cystic fibrosis or certain other conditions. It may also be used for other conditions as determined by your doctor.
Palipase MT 20 delayed-release capsules is a digestive enzyme combination. It works by helping the body to digest protein, starch, and fat.
Palipase MT 20 indications
Palipase MT 20 (pancrelipase delayed-release minimicrospheres) Capsules are indicated for patients with pancreatic exocrine insufficiency as is often associated with:
- cystic fibrosis
- chronic pancreatitis
- post-pancreatectomy
- post-gastrointestinal bypass surgery (e.g., Billroth II gastroenterostomy)
- ductal obstruction from neoplasm (e.g., of the pancreas or common bile duct)
How should I use Palipase MT 20?
Use Palipase MT 20 as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Palipase MT 20 by mouth with each meal or snack as directed by your doctor. Do not take without food.
- Swallow Palipase MT 20 whole with enough liquid to swallow it completely. Do not break, crush, chew, or hold Palipase MT 20 in your mouth before swallowing. Doing so may increase the risk of mouth or tongue irritation from Palipase MT 20. Follow with a glass of water or juice. Contact your doctor if you experience mouth or tongue irritation while taking Palipase MT 20.
- If you cannot swallow the capsule whole, you may open it and sprinkle the contents over soft, bland food. Do NOT crush or chew the contents of the capsule. Ask your doctor or pharmacist if you have questions about what kind of food can be mixed with Palipase MT 20.
- If you mix the medicine with food, swallow the entire mixture right away. Do not save it for use at a later time. Drink a glass of water or juice after you swallow the mixture.
- Continue to take Palipase MT 20 even if you feel well. Do not miss any doses.
- If you miss a dose of Palipase MT 20, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once or take a dose without a snack or a meal.
Ask your health care provider any questions you may have about how to use Palipase MT 20.
Uses of Palipase MT 20 in details
This medication contains digestive enzymes to help break down and digest fats, starch, and proteins in food. It is used in conditions where the pancreas cannot make or does not release enough digestive enzymes into the small intestines to digest the food (e.g., chronic pancreatitis, cystic fibrosis, cancer of the pancreas, post-pancreatectomy, post-gastrointestinal bypass surgery).
How to use Palipase MT 20
Some brands of this medication have a Medication Guide provided by your pharmacist. If one is available, read the Medication Guide before your start taking this medication and each time you get a refill. If you have any questions, consult your doctor or pharmacist.
Take this medication by mouth with meals and snacks as directed by your doctor. Swallow the capsule whole. Do not crush or chew the capsules or keep the capsules in your mouth. Doing so can irritate the mouth and also change the way the medication works.
If swallowing is difficult, then the capsule may be opened and the contents mixed in a small amount of liquid or soft food that does not need to be chewed (such as room-temperature applesauce). Do not mix the contents of the capsule with alkaline food or liquid (such as milk, ice cream, tea). Consult your doctor or pharmacist for more information about what foods/liquids (such as infant formula, breast milk) to avoid when mixing. Swallow the food or liquid right away, making sure not to chew the medication. Drink a glass of water or juice after swallowing the food to make sure all the medication is swallowed. Do not save the medication mixture for later.
Dosage is based on your medical condition, diet, weight, and response to treatment. Do not take more capsules in a day than prescribed by your doctor. Your condition will not improve any faster, and your risk of side effects will increase.
Drink plenty of fluids while taking this medication unless your doctor tells you otherwise.
Use this medication regularly to get the most benefit from it. Take it with every meal or snack.
If your doctor has recommended that you follow a special diet, it is very important to follow the diet to get the most benefit from this medication.
Do not change brands or dosage forms of pancrelipase without consulting your doctor or pharmacist. Different products may contain different amounts of the digestive enzymes.
Inform your doctor if your condition persists or worsens.
Palipase MT 20 description
Each minimicrospheres capsule contains pancreas powder 150 mg corresponding to Amylase (Palipase MT 20 MT 20) 8,000 Ph Eur units, Lipase (Palipase MT 20 MT 20) 10,000 Ph Eur units and Protease (Palipase MT 20 MT 20) 600 Ph Eur units produced from porcine pancreatic tissue.
Excipients/Inactive Ingredients: Pellet Core: Macrogol 4000.
Pellet Coating: Hypromellose phthalate, cetyl alcohol, triethyl citrate, dimethicone 1,000.
Capsule: Gelatin, iron oxide (E172), titanium dioxide (E171), sodium lauryl sulphate.
Palipase MT 20 dosage
Clinical experience should dictate initial starting dose. Doses should be taken during meals or snacks, not before or after. Do not take without food.
Adults and Children Over 6 Years Old
Usual initial starting dosage is one to two Palipase MT 20 (pancrelipase delayed-released capsules) Capsules per meal or snack.
Children Under 6 Years Old
Usual initial starting dosage is up to one Palipase MT 20 (pancrelipase delayed-released capsules) Capsule per meal or snack.
For cystic fibrosis patients, typical doses are 1,500 - 3,000 USP Lipase (Palipase MT 20 MT 20) units/kg/meal. Dosage should be adjusted according to the severity of the disease, control of steatorrhea and maintenance of good nutritional status. Doses in excess of 6,000 USP Lipase (Palipase MT 20 MT 20) units/kg/meal are not recommended.
Dose increases, if required, should occur with careful monitoring of body weight and stool fat content. When changing strengths of pancreatic enzyme products, care should be taken to maintain equivalent Lipase (Palipase MT 20 MT 20) units for each divided dosage.
It is important to ensure adequate hydration of patients at all times while taking pancreatic enzymes.
Where swallowing of capsules is difficult, the capsules may be carefully opened and the MINIMICROSPHERES added to a small amount of soft food, with a pH less than 5.5. The soft food should be swallowed immediately without chewing and followed with a glass of water or juice to insure swallowing.
How supplied
Palipase MT 20 MINIMICROSPHERES (Pancrelipase Delayed-release Capsules, USP) are available in a two-piece gelatin capsule (brown opaque top half, natural transparent bottom half) imprinted in white with "SOLVAY" and "1210". Each capsule contains tan-colored delayed-release MINIMICROSPHERES of pancrelipase supplied in bottles of:
100.......NDC 0032-1210-01
250.......NDC 0032-1210-07
Palipase MT 20 (pancrelipase delayed-released capsules) Capsules must be stored at 25
Palipase MT 20 interactions
See also:
What other drugs will affect Palipase MT 20?
Antacids should not be taken concomitantly with Palipase MT 20 as the alkaline pH may destroy the enteric-coating.
Palipase MT 20 side effects
See also:
What are the possible side effects of Palipase MT 20?
Diarrhea, constipation, headache, abdominal pain/cramps/bloating, gas, dizziness, cough, nausea, or vomiting may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if any of these rare but very serious side effects occur: severe constipation, severe stomach/abdominal discomfort, frequent/painful urination, joint pain.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Palipase MT 20 contraindications
See also:
What is the most important information I should know about Palipase MT 20?
you are allergic to any ingredient in Palipase MT 20 Delayed-Release Capsules or to pork protein.
you have inflammation of the pancreas (pancreatitis) or a flare-up of long-term pancreas problems.
Active ingredient matches for Palipase MT 20:
List of Palipase MT 20 substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Lipram UL Capsules (Enteric-Coated) | |
| Palcaps 20 | |
| Palipase | |
| Palipase MT 16 | |
| Palpeon DR 10 | |
| Palpeon DR 20 | |
| Palpeon MT 20 | |
| Paltrase V8 | |
| Pancre Zyme | |
| Capsule; Oral; Lipase 30, 000 units; Protease 8, 000 units; Amylase 30, 000 units | |
| Pancrease MT Capsules (Enteric-Coated) | |
| Pancrease MT-10 | |
| Pancrease MT-16 | |
| Pancrease MT-4 | |
| Pancreatic Enzyme | |
| Pancreatin 10 | |
| Pancrecarb MS Capsules (Enteric-Coated) | |
| Pancrelipase 10000 | |
| Pancrelipase 16,000 | |
| Pancrelipase 20000 | |
| Pancrelipase 4500 | |
| Pancrelipase 5000 | |
| Pancrelipase 8000 | |
| Pancrelipase EC | |
| Pancrelipase MT 16 | |
| Pancron 10 | |
| Pancron 10 Delayed-Release Capsules | |
| Pancron 20 | |
| Panlipase Cap (India) | |
| Panlipase Cap Lipase 25000 u, protease 62500u, amylase 74700 u. CAP / 10 (Sun (Solares)) | $ 4.34 |
| PANLIPASE CAP cap 10's (Sun (Solares)) | $ 4.34 |
| Panocaps MT 20 | |
| Panokase-16 | |
| Panzynorm Forte 20000 | |
| Tablet, Enteric Coated; Oral; Amylase 12, 000 IU; Lipase 20, 000 units; Protease 900 IU | |
| Protase (Taiwan) | |
| Protase 100 x 10's | |
| Protase 10 Blister x 10 Tablet | |
| S.P. Plex | |
| Tablet; Oral; Amylase 110 units; Lipase 18 units; Protease 95 units | |
| Sancase (Vietnam) | |
| Sancase 100 Tablet | |
| Trizyme | |
| Ultrase ECC | |
| Capsule, Enteric Coated; Oral; 20, 000 units Lipase; 4, 500 units Protease; 25, 000 units Amylase | |
| Ultrase MT12 | |
| Capsule, Enteric Coated; Oral; 39, 000 units Lipase; 12, 000 units Protease; 39, 000 units Amylase | |
| Ultrase MT20 | |
| Capsule, Enteric Coated; Oral; 65, 000 units Lipase; 20, 000 units Protease; 65, 000 units Amylase | |
| Viokases | |
| Tablet; Oral; Lipase 30, 000 units; Protease 8, 000 units; Amylase 30, 000 units | |
See 80 substitutes for Palipase MT 20 | |
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The results of a survey conducted on ndrugs.com for Palipase MT 20 are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Palipase MT 20. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
