• Penmox indications
• Uses of Penmox in details
• Penmox description
• Penmox dosage
• Penmox interactions
• Penmox side effects
• Penmox contraindications

What is Penmox?

Penicillins are used to treat infections caused by bacteria. They work by killing the bacteria or preventing their growth.

There are several different kinds of penicillins. Each is used to treat different kinds of infections. One kind of penicillin usually may not be used in place of another. In addition, penicillins are used to treat bacterial infections in many different parts of the body. They are sometimes given with other antibacterial medicines (antibiotics). Some of the penicillins may also be used for other problems as determined by your doctor. However, none of the penicillins will work for colds, flu, or other virus infections.

Penicillins are available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, penicillins are used in certain patients with the following medical conditions:

• Chlamydia infections in pregnant women—Penmox and ampicillin
• Gas gangrene—Penicillin G
• Helicobacter pylori-associated gastritis or peptic ulcer disease—Penmox
• Leptospirosis—Ampicillin and penicillin G
• Lyme disease—Penmox and penicillin V
• Typhoid fever—Penmox and ampicillin

Penmox indications

Infections of the Ear, Nose, and Throat

Penmox Capsules, Penmox for oral suspension, Penmox tablets (chewable) are indicated in the treatment of infections due to susceptible (ONLY β-lactamase–negative) isolates of Streptococcus species (α- and β-hemolytic isolates only), Streptococcus pneumoniae, Staphylococcus spp., or Haemophilus influenzae.

Infections of the Genitourinary Tract

Penmox Capsules, Penmox for oral suspension, Penmox tablets (chewable) are indicated in the treatment of infections due to susceptible (ONLY β-lactamase–negative) isolates of Escherichia coli, Proteus mirabilis, or Enterococcus faecalis.

Infections of the Skin and Skin Structure

Penmox Capsules, Penmox for oral suspension, Penmox tablets (chewable) are indicated in the treatment of infections due to susceptible (ONLY β-lactamase-negative) isolates of Streptococcus spp. (α- and β-hemolytic isolates only), Staphylococcus spp., or E. coli.

Infections of the Lower Respiratory Tract

Penmox Capsules, Penmox for oral suspension, Penmox tablets (chewable) are indicated in the treatment of infections due to susceptible (ONLY β-lactamase-negative) isolates of Streptococcus spp. (α- and β-hemolytic isolates only), S. pneumoniae, Staphylococcus spp., or H. influenzae.

Helicobacter pylori Infection

Triple therapy for Helicobacter pylori with clarithromycin and lansoprazole:

Penmox, in combination with clarithromycin plus lansoprazole as triple therapy, is indicated for the treatment of patients with H. pylori infection and duodenal ulcer disease (active or 1 year history of a duodenal ulcer) to eradicate H. pylori. Eradication of H. pylori has been shown to reduce the risk of duodenal ulcer recurrence.

Dual therapy for H. pylori with lansoprazole:

Penmox, in combination with lansoprazole delayed-release capsules as dual therapy, is indicated for the treatment of patients with H. pylori infection and duodenal ulcer disease (active or 1 year history of a duodenal ulcer) who are either allergic or intolerant to clarithromycin or in whom resistance to clarithromycin is known or suspected. Eradication of H. pylori has been shown to reduce the risk of duodenal ulcer recurrence.

Usage

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Penmox and other antibacterial drugs, Penmox should be used only to treat infections that are proven or strongly suspected to be caused by bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

How should I use Penmox?

Use Penmox suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Penmox suspension by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Shake well before each use.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• Penmox suspension may be mixed with formula, milk, fruit juice, water, ginger ale, or other cold drinks. If you mix Penmox suspension, take it at once after mixing. Be sure that the entire dose is swallowed.
• To clear up your infection completely, take Penmox suspension for the full course of treatment. Keep taking it even if you feel better in a few days.
• If you miss a dose of Penmox suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Penmox suspension.

Uses of Penmox in details

Use: Labeled Indications

Ear, nose, and throat infections (pharyngitis/tonsillitis, otitis media):

Immediate release: Treatment of infections due to beta-lactamase-negative Streptococcus spp. (alpha- and beta-hemolytic isolates only), Streptococcus pneumoniae, Staphylococcus spp., or Haemophilus influenzae.

Extended release: Treatment of tonsillitis and/or pharyngitis due to Streptococcus pyogenes in adults and pediatric patients ≥12 years of age.

Genitourinary tract infections: Immediate release: Treatment of infections of the genitourinary tract due to beta-lactamase-negative Escherichia coli, Proteus mirabilis, or Enterococcus faecalis.

Helicobacter pylori eradication: Immediate release: Eradication of H. pylori to reduce the risk of duodenal ulcer recurrence as a component of combination therapy in patients with active or 1-year history of duodenal ulcer disease.

Lower respiratory tract infections (including pneumonia): Immediate release: Treatment of infections of the lower respiratory tract due to beta-lactamase-negative Streptococcus spp. (alpha- and beta-hemolytic strains only), S. pneumoniae, Staphylococcus spp., or H. influenzae.

Rhinosinusitis, acute bacterial: Immediate release: Treatment of infections due to beta-lactamase-negative Streptococcus spp. (alpha- and beta-hemolytic isolates only), S. pneumoniae, Staphylococcus spp., or H. influenzae.

Skin and skin structure infections: Immediate release: Treatment of infections of the skin and skin structure due to beta-lactamase-negative Streptococcus spp. (alpha- and beta-hemolytic strains only), Staphylococcus spp., or E. coli.

Off Label Uses

Actinomycosis

Data from a small retrospective study suggest that Penmox may be beneficial for the treatment of actinomycosis.

Prosthetic joint infection

Based on the IDSA guidelines for the management of prosthetic joint infection (PJI), Penmox is an effective and recommended agent for chronic oral antimicrobial suppression of PJI with beta-hemolytic streptococci, Enterococcus spp. (penicillin susceptible), and Cutibacterium spp. after completion of parenteral therapy.

Penmox description

A broad-spectrum semisynthetic antibiotic similar to ampicillin except that its resistance to gastric acid permits higher serum levels with oral administration. Penmox is commonly prescribed with clauvanic acid (a beta lactamase inhibitor) as it is susceptible to beta-lacatamase degradation. [PubChem]

Penmox dosage

Penmox Dosage

Generic name: Penmox 775mg

Dosage form: tablet, film coated, extended release

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Tonsillitis and/or Pharyngitis

The recommended dose of Penmox is 775 mg once daily taken within 1 hour of finishing a meal for 10 days. The full 10-day course of therapy should be completed for effective treatment of tonsillitis and/or pharyngitis secondary to S. pyogenes.

Do not chew or crush tablet.

More about Penmox (Penmox)

• Side Effects
• During Pregnancy or Breastfeeding
• Dosage Information
• Drug Images
• Drug Interactions
• Support Group
• Pricing & Coupons
• En Espanol
• 1 Review - Add your own review/rating

Consumer resources

• Penmox
• Penmox extended-release tablets
• Penmox (Advanced Reading)

• Other brands: Amoxil, Penmox, Penmox, DisperMox, More (2) »

Professional resources

• Penmox (FDA)
• Penmox (AHFS Monograph)

Related treatment guides

• Bronchiectasis
• Dental Abscess
• Tonsillitis/Pharyngitis

Penmox interactions

See also:
What other drugs will affect Penmox?

Allopurinol: Concurrent administration may increase the incidence of rash and other allergic skin reactions.

Anticoagulants: There are rare reports of prolongation of prothrombin time in patients concomitantly on Penmox. It is recommended that appropriate monitoring is carried out when Penmox is prescribed concurrently with anticoagulants.

Oral Contraceptives:

In common with other antibiotics, Penmox may affect the gut flora, leading to lower oestrogen reabsorption and reduced efficacy of combined oral contraceptives.

Probenecid: Decreases the renal tubular secretion of Penmox. Concurrent use with Penmox may result in increased and prolonged blood levels of Penmox.

Laboratory Tests: Glucose in Urine: Due to the high urinary concentrations of Penmox, false positive readings are common with chemical methods.

The use of enzymatic glucose oxidase methods is recommended, as there is no interference from Penmox.

Penmox side effects

See also:
What are the possible side effects of Penmox?

. Overdosage

In case of overdosage, discontinue medication, treat symptomatically, and institute supportive measures as required. If the overdosage is very recent and there is no contraindication, an attempt at emesis or other means of removal of drug from the stomach may be performed. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of Penmox are not associated with significant clinical symptoms and do not require gastric emptying.3

Interstitial nephritis resulting in oliguric renal failure has been reported in a small number of patients after overdosage with Penmox.

Crystalluria, in some cases leading to renal failure, has also been reported after Penmox overdosage in adult and pediatric patients. In case of overdosage, adequate fluid intake and diuresis should be maintained to reduce the risk of Penmox crystalluria.

Renal impairment appears to be reversible with cessation of drug administration. High blood levels may occur more readily in patients with impaired renal function because of decreased renal clearance of Penmox. Penmox may be removed from circulation by hemodialysis.

Penmox contraindications

See also:
What is the most important information I should know about Penmox?

Do not use this medication if you are allergic to Penmox or to any other penicillin antibiotic, such as ampicillin (Principen, Unasyn), dicloxacillin (Dycill, Dynapen), oxacillin (Bactocill), or penicillin (Bicillin L-A, PC Pen VK, Pfizerpen), and others.

Before using Penmox, tell your doctor if you are allergic to cephalosporins such as Omnicef, Cefzil, Ceftin, Keflex, and others. Also tell your doctor if you have asthma, liver or kidney disease, a bleeding or blood clotting disorder, mononucleosis (also called "mono"), or any type of allergy.

Penmox can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom or diaphragm with spermicide) to prevent pregnancy while taking Penmox.

Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Penmox will not treat a viral infection such as the common cold or flu.

Do not share this medication with another person, even if they have the same symptoms you have.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking Penmox and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

Active ingredient matches for Penmox:

Amoxicillin in Bangladesh, Indonesia.

Unit description / dosage (Manufacturer)	Price, USD
Penmox 250 mg x 10 x 10's	$ 14.94
Penmox 500 mg x 10 x 10's	$ 31.13
Penmox 125 mg/5 mL x 60 mL x 1's	$ 2.06
Penmox Forte 250 mg/5 mL x 60 mL x 1's	$ 2.99
Caplets; Oral; Amoxicillin 500 mg
Capsules; Oral; Amoxicillin 250 mg
Syrup; Oral; Amoxicillin 125 mg / 5 ml
List of Penmox substitutes (brand and generic names):
Penimox (Switzerland)
Capsules; Oral; Amoxicillin Trihydrate 375 mg (Ibsa)
Penmox Forte (Indonesia)
Penmox/Penmox Forte (Indonesia)
Penmoxy (Vietnam)
Penmoxy 250 mg x 1 Bottle x 60 mL
PENOM
PENOM 125MG DRY SYRUP 1 bottle / 60 ML dry syrup each (Apostle Remedies)	$ 0.35
PENOM 250MG CAPSULE 1 strip / 10 capsules each (Apostle Remedies)	$ 0.38
PENOM 250MG TABLET DT 1 strip / 10 tablet dts each (Apostle Remedies)	$ 0.40
PENOM 500MG CAPSULE 1 strip / 10 capsules each (Apostle Remedies)	$ 0.69
PENOM KID 125MG TABLET 1 strip / 10 tablets each (Apostle Remedies)	$ 0.22
Penom 250mg Capsule (Apostle Remedies)	$ 0.04
Penom 250mg Tablet DT (Apostle Remedies)	$ 0.04
Penom 500mg Capsule (Apostle Remedies)	$ 0.07
Penom 125mg Tablet (Apostle Remedies)	$ 0.02
Pentamox (Bangladesh)
Penticlox (Mexico)
Pentus (Paraguay)
Penvicilin (Brazil)
Perlium Amoxival (France, United Kingdom)
Perlium Amoxival 100 Porcs (France)
Phamoxi (Germany)
Suspension; Oral; Amoxicillin Trihydrate 250 mg / 5 ml (Phamos)
Tablet; Oral; Amoxicillin Trihydrate 1000 mg (Phamos)
Tablets; Oral; Amoxicillin Trihydrate 1000 mg (Phamos)
Phamoxi TS
Suspension; Oral; Amoxicillin Trihydrate 250 mg / 5 ml
Pharex Amoxicillin Trihydrate (Philippines)
Pharex Amoxicillin Trihydrate 250 mg x 100's	$ 10.11
Pharex Amoxicillin Trihydrate 500 mg x 100's	$ 16.04
Pharex Amoxicillin Trihydrate 125 mg/5 mL x 60 mL	$ 1.49
Pharex Amoxicillin Trihydrate 250 mg/5 mL x 60 mL	$ 1.93
Pharex Amoxicillin Trihydrate 100 mg/1 mL x 10 mL	$ 1.24
Pharmamox (Philippines)
Pharmamox 250 mg x 100's (Rivopharm)	$ 15.93
Pharmamox 500 mg x 50's (Rivopharm)	$ 14.49
Pharmamox 125 mg/5 mL x 30 mL (Rivopharm)	$ 0.96
Pharmamox 125 mg/5 mL x 60 mL (Rivopharm)	$ 1.56
Pharmamox 250 mg/5 mL x 30 mL (Rivopharm)	$ 1.38
Pharmamox 250 mg/5 mL x 60 mL (Rivopharm)	$ 2.22
Pharmamox 100 mg/1 mL x 10 mL (Rivopharm)	$ 1.09
Capsules; Oral; Amoxicillin Trihydrate 250 mg (Rivopharm)
Capsules; Oral; Amoxicillin Trihydrate 500 mg (Rivopharm)
Drops; Oral; Amoxicillin Trihydrate 100 mg / ml (Rivopharm)
Suspension; Oral; Amoxicillin Trihydrate 125 mg / 5 ml (Rivopharm)
Suspension; Oral; Amoxicillin Trihydrate 250 mg / 5 ml (Rivopharm)
Pharmox (Brazil)
Pharmoxin (South Africa)
See 6154 substitutes for Penmox

References

1. DailyMed. "AMOXICILLIN; CLAVULANATE POTASSIUM: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
2. PubChem. "amoxicillin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
3. DrugBank. "amoxicillin". http://www.drugbank.ca/drugs/DB01060 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Penmox are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Penmox. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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Information checked by Dr. Sachin Kumar, MD Pharmacology