Benzoyl Peroxide (Perclin) and Clindamycin (Perclin) combination is used to treat acne. It works by killing the bacteria that cause acne and by keeping the skin pores clean (tiny openings on the skin).
This medicine is available only with your doctor's prescription.
Perclin indications
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Perclin Gel is indicated for the topical treatment of mild to moderate acne vulgaris, particularly inflammatory lesions, in adults and adolescents aged 12 years and above.
Perclin description
Perclin gel contains Clindamycin (Perclin) (as 1.2% Clindamycin (Perclin) phosphate) at a concentration equivalent to 1% w/w (10 mg/g) and Benzoyl Peroxide (Perclin) 5% w/w (50 mg/g).
Adults and Adolescents (aged 12 years and above): Perclin Gel should be applied once daily in the evening, to the entire affected area.
Patients should be advised that excessive application will not improve efficacy, but may increase the risk of skin irritation. If excessive dryness or peeling occurs, frequency of application should be reduced or application temporarily interrupted.
An effect on inflammatory and non-inflammatory lesions may be seen as early as week 2-5 of treatment.
The safety and efficacy of Perclin Gel has not been studied beyond 12 weeks in acne vulgaris clinical trials. Treatment with Perclin Gel should not exceed more than 12 weeks of continuous use.
Paediatric Population: The safety and efficacy of Perclin Gel has not been established in children under 12 years of age, therefore Perclin Gel is not recommended for use in this population.
Elderly Patients: No specific recommendations.
Administration: Perclin Gel should be applied in a thin film after washing gently with a mild cleanser and fully drying. If the gel does not rub into the skin easily, too much is being applied.
Hands should be washed after application.
Perclin interactions
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No formal drug-drug interaction studies have been performed with Perclin Gel.
Concomitant topical antibiotics, medicated or abrasive soaps and cleansers, soaps and cosmetics that have a strong drying effect, and products with high concentrations of alcohol and/or astringents, should be used with caution as a cumulative irritant effect may occur.
Perclin Gel should not be used in combination with erythromycin-containing products due to possible antagonism to the Clindamycin (Perclin) component.
Clindamycin (Perclin) has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore caution should be exercised with concomitant use.
Concomitant application of Perclin Gel with tretinoin, isotretinoin and tazarotene should be avoided since Benzoyl Peroxide (Perclin) may reduce their efficacy and increase irritation. If combination treatment is required, the products should be applied at different times of the day (e.g. one in the morning and the other in the evening).
Using topical Benzoyl Peroxide (Perclin)-containing preparations at the same time as topical sulphonamide-containing products may cause skin and facial hair to temporarily change colour (yellow/orange).
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
Itching (pruritus)
Dry skin
Skin redness
Skin tingling
The side effects listed above may not include all of the side effects reported by the drug’s manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
Tell your doctor if you do not feel well while
you are using Perclin Gel.
Perclin Gel helps most people with
acne but it may have unwanted side effects in a
few people.
All medicines can have side effects. Sometimes
they are serious, most of the time they are not.
You may need medical treatment if you get some
of these side effects.
The gel may cause slight itching and burning
and make your skin feel warm, especially
when it is first applied. You may also notice
flaking and redness of your skin during the
first few weeks of use. These effects are
normal; if they bother you, try using the
product less often for a while, or stop for a few
days and start again.
If you suffer severe burning, peeling or
itching, or other effects not mentioned in this
leaflet, you should stop using Perclin
Gel and go back to your doctor for advice.
Perclin contraindications
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Perclin Gel must not be administered to patients with known hypersensitivity to Clindamycin (Perclin), lincomycin, Benzoyl Peroxide (Perclin), or any of the excipients in the formulation.
DailyMed. "PERMETHRIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
DailyMed. "BENZOYL PEROXIDE; ERYTHROMYCIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
The results of a survey conducted on ndrugs.com for Perclin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Perclin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
User reports
Consumer reported useful
No survey data has been collected yet
Consumer reported price estimates
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Consumer reported time for results
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