What is Poen-Caina?
Poen-Caina eye drops are used to numb the eye before surgery, certain tests, or procedures. The eye drops are used to prevent pain during the procedure.
Poen-Caina belongs to the group of medicines called local anesthetics. It works by blocking the pain signals at the nerve endings in the eye.
Poen-Caina is to be administered only by or under the direct supervision of an eye doctor.
Poen-Caina hydrochloride ophthalmic solution is indicated for procedures in which a topical ophthalmic anesthetic is indicated: corneal anesthesia of short duration, e.g. tonometry, gonioscopy, removal of corneal foreign bodies, and for short corneal and conjunctival procedures.
How should I use Poen-Caina?
Use Poen-Caina as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- To use Poen-Caina in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
- To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
- Poen-Caina is clear to straw-colored. If Poen-Caina becomes darker, do not use it. Throw away any medicine that has darkened.
- Poen-Caina contains benzalkonium chloride, a preservative that may be absorbed by soft contact lenses. Ask your doctor about how long you should wait to put your contacts back in after using Poen-Caina.
- If you miss a dose of Poen-Caina, contact your doctor.
Ask your health care provider any questions you may have about how to use Poen-Caina.
Uses of Poen-Caina in details
Poen-Caina is used as topical anesthesia in eyes before surgery, certain tests or procedures.
Poen-Caina is a topical anesthetic drug of the amino ester group. It is available as its hydrochloride salt in ophthalmic solutions at a concentration of 0.5%. [Wikipedia]
Dosage: Removal of foreign bodies and sutures, and for tonometry: 1 to 2 drops (in single instillations) in each eye before operating.
Short corneal and conjunctival procedures: 1 drop in each eye every 5 to 10 minutes for 5 to 7 doses.
NOTE: Poen-Caina (proparacaine hydrochloride ophthalmic solution, USP) 0.5% should be clear to straw-color. If the solution becomes darker, discard the solution.
Data is temporarily not available
Poen-Caina side effects
Occasional temporary stinging, burning and conjunctival redness may occur with the use of Poen-Caina. A rare, severe, immediate-type, apparently hyperallergic corneal reaction characterized by acute, intense and diffuse epithelial keratitis, a gray, ground glass appearance, sloughing of large areas of necrotic epithelium, corneal filaments and, sometimes, iritis with descemetitis has been reported.
Allergic contact dermatitis from Poen-Caina with drying and fissuring of the fingertips has also been reported.
Poen-Caina hydrochloride ophthalmic solution should be considered contraindicated in patients with known hypersensitivity to any of the ingredients of this preparation.
Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
No information provided.
Carcinogenesis, Mutagenesis, Impairment of Fertility
Long-term studies in animals have not been performed to evaluate carcinogenic potential, mutagenicity, or possible impairment of fertility in males or females.
Pregnancy Category C: Animal reproduction studies have not been conducted with Poen-Caina hydrochloride ophthalmic solution 0.5%. It is also not known whether Poen-Caina hydrochloride can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Poen-Caina hydrochloride should be administered to a pregnant woman only if clearly needed.
It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Poen-Caina hydrochloride is administered to a nursing woman.
Safety and effectiveness of Poen-Caina hydrochloride ophthalmic solution in pediatric patients have been established. Use of Poen-Caina hydrochloride is supported by evidence from adequate and well-controlled studies in adults and children over the age of twelve, and safety information in neonates and other pediatric patients.
No overall clinical differences in safety or effectiveness have been observed between the elderly and other adult patients
Active ingredient matches for Poen-Caina:
List of Poen-Caina substitutes (brand and generic names)
|Sort by popularity|
|Unit description / dosage (Manufacturer)||Price, USD|
|CARE CAIN 0.5% EYE DROPS 1 packet / 10 ML eye drop each (Ajanta Pharma Ltd)||$ 1.22|
|CARE CAIN 0.5% EYE DROPS 1 packet / 5 ML eye drop each (Ajanta Pharma Ltd)||$ 0.68|
|Liquid; Ophthalmic; Topical; Proxymetacain Hydrochloride 0.5% (Dioptic)|
|IDOPE EYE DROPS 1 packet / 5 ML eye drop each (Intas Pharmaceuticals Ltd)||$ 0.95|
|Idope NA Eye Drop (Intas Pharmaceuticals Ltd)||$ 0.95|
|Kainair (United States)|
|Solution; Ophthalmic; Proparacaine Hydrochloride 0.5% (Pharmafair)|
|Minims Proxymetacaine (South Africa, United Kingdom)|
|Solution; Ophthalmic; Proparacaine Hydrochloride 0.5%|
|Minims Proxymetacaine Hydrochloride (South Africa)|
|Minims Proxymetacaine Hydrochloride 0.5% (United Kingdom)|
|Ophthaine (United States)|
|Solution; Ophthalmic; Proparacaine Hydrochloride 0.5% (Apothecon)|
|0.5 % x 5ml (Sunways)||$ 0.68|
|PARACAIN EYE DROP 1 packet / 5 ML eye drop each (Sunways)||$ 0.74|
|PARACAIN eye drops 0.5 % x 5ml (Sunways)||$ 0.68|
|Paracain 0.5% v/v Solution (Sunways)||$ 0.74|
|Solution; Ophthalmic; Proparacaine Hydrochloride 0.5%|
|PARACAINE EYE DROP 1 packet / 5 ML eye drop each (Ajanta Pharma Ltd)||$ 0.83|
|Parcaine (United States)|
|Drops; Ophthalmic; Proxymetacaine Hydrochloride 0.5%|
|Solution; Ophthalmic; Proparacaine 0.05%|
|Proparacaina L.CH. (Chile)|
|Proparacaina Lch (Peru)|
|Proparacaine Wu Fu (Taiwan)|
|Proxymetacaine (Australia, Belgium, Bulgaria, Canada, China, Colombia, Estonia, Greece, Hong Kong, Iceland, Latvia, Lithuania, Malaysia, New Zealand, Norway, Pakistan, Peru, Philippines, Poland, Singapore, Slovenia, Switzerland, Taiwan, Turkey, United States, Venezuela)|
|Drops; Ophthalmic; Proxymetacaine Hydrochloride 5 mg / ml|
|SENSOCHEK 0.5% EYE DROPS 1 packet / 5 ML eye drop each (Indoco Remedies Ltd)||$ 0.83|
|Sensochek 0.5% Eye Drop (Indoco Remedies Ltd)||$ 0.83|
|SURAC eye drops 0.5 % x 5ml (Salvador)||$ 0.68|
|XYLOKING eye drops 0.5 % w/v x 5ml (Gatle)||$ 0.87|
- PubChem. "proparacaine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "proparacaine". http://www.drugbank.ca/drugs/DB00807 (accessed September 17, 2018).
- Wikipedia. "proparacaine: Link to the compound information in Wikipedia.". https://en.wikipedia.org/wiki/Proxym... (accessed September 17, 2018).
- MeSH. "Anesthetics, Local". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
- European Chemicals Agency - ECHA. "proxymetacaine: The European Chemicals Agency (ECHA) is an agency of the European Union which is the driving force among regulatory authorities in implementing the EU's groundbreaking chemicals legislation for the benefit of human health and the environment as well as for innovation and competitiveness.". https://echa.europa.eu/ (accessed September 17, 2018).
ReviewsThe results of a survey conducted on ndrugs.com for Poen-Caina are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Poen-Caina. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
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Information checked by Dr. Sachin Kumar, MD Pharmacology