What is Predmycin P?
Treating infections and relieving the redness, irritation, and discomfort associated with certain eye problems.
Predmycin P drops is an antibiotic and steroid combination. It works by inhibiting the growth of bacteria and decreasing inflammation.
Predmycin P indications
this drug eases redness, irritation, and swelling due to inflammation of the eye.
How should I use Predmycin P?
Use Predmycin P drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Shake well before each use.
- To use Predmycin P drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
- To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
- If your doctor prescribed more than 1 eye medicine, ask the best order for using each medicine.
- Do not wear contact lenses while you are using Predmycin P drops. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them.
- If you miss a dose of Predmycin P drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Predmycin P drops.
Predmycin P dosage
TO TREAT THE EYE: Instill 1 or 2 drops every 3 or 4 hours, or more frequently as required. Acute infections may require administration every 30 minutes, with frequency of administration reduced as the infection is brought under control. TO TREAT THE LIDS: Instill 1 or 2 drops in the eye every 3 to 4 hours, close the eye and rub the excess on the lids and lid margins.
Not more than 20 milliliters should be prescribed initially and the prescription should not be refilled without further evaluation as outlined in the section above.
Predmycin P interactions
Aminoglutethimide
May lead to loss of Prednisolone (Predmycin P)-induced adrenal suppression.
Amphotericin B
Coadministration may be followed by cardiac enlargement and CHF.
Anticholinesterase agents
Coadministration may produce severe weakness in patients with myasthenia gravis. If possible, withdraw anticholinesterase agent 24 h prior to starting Prednisolone (Predmycin P).
Antidiabetic agents
Because Prednisolone (Predmycin P) may increase blood glucose concentrations, dose adjustments of antidiabetic agents may be required.
Aspirin and other salicylates, NSAIDs
Risk of GI bleeding may be increased. Salicylate clearance may be increased.
CYP3A4 inducers (eg, barbiturates, carbamazepine, phenytoin, rifampin)
Prednisolone (Predmycin P) metabolism may be increased, reducing Prednisolone (Predmycin P) plasma levels and necessitating an increase in dosage.
CYP3A4 inhibitors (eg, estrogens [eg, hormonal contraceptives], ketoconazole, macrolide antibiotics [eg, erythromycin])
Prednisolone (Predmycin P) metabolism may be decreased, increasing Prednisolone (Predmycin P) plasma levels and increasing the risk of adverse reactions.
Cholestyramine
Prednisolone (Predmycin P) clearance may be increased, reducing plasma levels and decreasing the efficacy.
Cyclosporine
Increased activity of cyclosporine and Prednisolone (Predmycin P) may occur. Convulsions have been reported with coadministration of corticosteroids and cyclosporine.
Digitalis glycosides
Because of possible hypokalemia, the risk of arrhythmias may be increased.
Isoniazid
Isoniazid serum levels may be reduced, decreasing the efficacy.
Potassium-depleting agents (eg, amphotericin B, diuretics)
Risk of hypokalemia may be increased.
Toxoids and live or inactivated vaccines
Because of inhibition of antibody response, patients on prolonged Prednisolone (Predmycin P) therapy may exhibit a diminished response to toxoids and live or inactivated vaccines. Replication of some organisms contained in live attenuated vaccines may be potentiated.
Warfarin
Because data are conflicting, monitor coagulation indices frequently.
Predmycin P side effects
See also:
What are the possible side effects of Predmycin P?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:
pain behind your eyes, sudden vision changes, severe headache;
sudden eye irritation;
blurred vision, tunnel vision, eye pain, or seeing halos around lights; or
signs of new eye infection, such as swelling, draining, or crusting of your eyes.
Less serious side effects may include:
temporary cloudy vision;
increased sensitivity to light; or
mild stinging, burning, itching, or irritation in your eyes
Predmycin P contraindications
See also:
What is the most important information I should know about Predmycin P?
You should not use this medication if you are allergic to Prednisolone (Predmycin P) or other steroids, or if you have certain types of infection (viral, fungal, or bacterial) that can affect your eyes.
If you have any of these other conditions, you may need a dose adjustment or special tests to safely use Prednisolone (Predmycin P) ophthalmic:
glaucoma;
recent cataract surgery; or
herpes simplex
Active ingredient matches for Predmycin P:
Neomycin/Polymyxin B/Prednisolone in Thailand.
Neomycin sulfate 05%/polymyxin B sulfate/Prednisolone acetate 05% in Thailand.
Neomycin sulfate/polymyxin B sulfate/Prednisolone acetate in Belgium.
List of Predmycin P substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Conjunctilone-S (Portugal) | |
| Conjunctin-S (Austria) | |
| Mycinopred (Switzerland, Germany) | |
| Drops; Ophthalmic; Neomycin Sulfate 3.5 mg; Polymyxin B Sulfate 5000 IU; Prednisolone Acetate 5 mg / ml (Allergan) | |
| Mycinopred Liquifilm | |
| Drops; Ophthalmic; Neomycin Sulfate 3.5 mg; Polymyxin B Sulfate 5000 IU; Prednisolone Acetate 5 mg / ml | |
| neomycin sulfate 05%/polymyxin B sulfate/Prednisolone acetate 05% (Thailand) | |
| neomycin sulfate/polymyxin B sulfate/Prednisolone acetate (Taiwan) | |
| Neomycin/ polymyxin b/ prednisolone drops | |
| Neomycin/ polymyxin b/ prednisolone drops | |
| Neomycin/Polymyxin B/Prednisolone (Spain) | |
| Neomycin/Polymyxin B/Prednisolone Drops | |
| Nepocort (Peru) | |
| Poly-Pred Drops | |
| Poly-Pred Suspension | |
| Predmycin (Thailand) | |
| Predmycin-P Liquifilm (Netherlands) | |
| Prednisolone Acetate/Neomycin Sulfate/Polymyxin B Sulfate | |
References
- DailyMed. "PREDNISOLONE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "BACITRACIN ZINC; POLYMYXIN B SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "HYDROCORTISONE; NEOMYCIN SULFATE; POLYMYXIN B SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Predmycin P are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Predmycin P. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
