Consists of Nortriptyline, Pregabalin
What is Nortriptyline (Pregabid NT)?
Nortriptyline (Pregabid NT) is a tricyclic antidepressant. Nortriptyline (Pregabid NT) affects chemicals in the brain that may become unbalanced.
Nortriptyline (Pregabid NT) is used to treat symptoms of depression.
Nortriptyline (Pregabid NT) may also be used for purposes not listed in this medication guide.
Nortriptyline (Pregabid NT) indications
Nortriptyline (Pregabid NT)™ (Nortriptyline (Pregabid NT) HCl) is indicated for the relief of symptoms of depression. Endogenous depressions are more likely to be alleviated than are other depressive states.
How should I use Nortriptyline (Pregabid NT)?
Use Nortriptyline (Pregabid NT) as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Nortriptyline (Pregabid NT) comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Nortriptyline (Pregabid NT) refilled.
- Take Nortriptyline (Pregabid NT) by mouth with or without food.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- If you miss a dose of Nortriptyline (Pregabid NT), take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. If you take 1 dose daily at bedtime, do not take the missed dose the next morning.
Ask your health care provider any questions you may have about how to use Nortriptyline (Pregabid NT).
Uses of Nortriptyline (Pregabid NT) in details
Use: Labeled Indications
Major depression, unipolar: Treatment of symptoms of unipolar major depression
Off Label Uses
Chronic pain
Data from a limited number of patients in a randomized, double-blind, placebo-controlled study and a retrospective chart review suggest that Nortriptyline (Pregabid NT) may be beneficial for the treatment of chronic pain.
Based on European Federation of Neurological Societies guidelines, tricyclic antidepressants, such as Nortriptyline (Pregabid NT), are first-line for the management of PHN.
Smoking cessation
Data from controlled trials and meta-analyses indicate that Nortriptyline (Pregabid NT) is effective in promoting smoking cessation.
Guidelines from the US Preventative Task Force (USPSTF) and from the Public Health Service (PHS), along with a therapeutic position statement from the American Society of Health-System Pharmacists (ASHP) recommend behavioral interventions combined with FDA-approved pharmacotherapy (eg, nicotine, bupropion, varenicline) for smoking cessation. PHS and ASHP guidelines also state that Nortriptyline (Pregabid NT) or clonidine may be considered as second-line therapies.
Nortriptyline (Pregabid NT) description
Nortriptyline (Pregabid NT) hydrochloride, the N-demethylated active metabolite of amitriptyline, is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, Nortriptyline (Pregabid NT) does not affect mood or arousal, but may cause sedation. In depressed individuals, Nortriptyline (Pregabid NT) exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. Secondary amine TCAs, such as Nortriptyline (Pregabid NT), are more potent inhibitors of norepinephrine reuptake than tertiary amine TCAs, such as amitriptyline. TCAs also down-regulate cerebral cortical β-adrenergic receptors and sensitize post-synaptic serotonergic receptors with chronic use. The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred vision, dry mouth, constipation, urinary retention), respectively. See toxicity section below for a complete listing of side effects. Nortriptyline (Pregabid NT) exerts less anticholinergic and sedative side effects compared to the tertiary amine TCAs, amitriptyline and clomipramine. Nortriptyline (Pregabid NT) may be used to treat depression, chronic pain (unlabeled use), irritable bowel syndrome (unlabeled use), diabetic neuropathy (unlabeled use), post-traumatic stress disorder (unlabeled use), and for migraine prophylaxis (unlabeled use).
Nortriptyline (Pregabid NT) dosage
Nortriptyline (Pregabid NT) Dosage
Generic name: Nortriptyline (Pregabid NT) HYDROCHLORIDE 10mg
Dosage form: capsule
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Nortriptyline (Pregabid NT) is not recommended for children.
Nortriptyline (Pregabid NT) is administered orally in the form of capsules. Lower than usual dosages are recommended for elderly patients and adolescents. Lower dosages are also recommended for outpatients than for hospitalized patients who will be under close supervision. The physician should initiate dosage at a low level and increase it gradually, noting carefully the clinical response and any evidence of intolerance. Following remission, maintenance medication may be required for a longer period of time at the lowest dose that will maintain remission.
If a patient develops minor side effects, the dosage should be reduced. The drug should be discontinued promptly if adverse effects of a serious nature or allergic manifestations occur.
Usual Adult Dose – 25 mg three or four times daily; dosage should begin at a low level and be increased as required. As an alternate regimen, the total daily dosage may be given once a day. When doses above 100 mg daily are administered, plasma levels of Nortriptyline (Pregabid NT) should be monitored and maintained in the optimum range of 50 to 150 ng/mL. Doses above 150 mg/day are not recommended.
Elderly and Adolescent Patients – 30 to 50 mg/day, in divided doses, or the total daily dosage may be given once a day.
Switching a Patient To or From a Monoamine Oxidase Inhibitor (MAOI) Intended to Treat Psychiatric Disorders
At least 14 days should elapse between discontinuation of an MAOI intended to treat psychiatric disorders and initiation of therapy with Nortriptyline (Pregabid NT). Conversely, at least 14 days should be allowed after stopping Nortriptyline (Pregabid NT) before starting an MAOI intended to treat psychiatric disorders.
Use of Nortriptyline (Pregabid NT) With Other MAOIs, Such as Linezolid or Methylene Blue
Do not start Nortriptyline (Pregabid NT) in a patient who is being treated with linezolid or intravenous methylene blue because there is increased risk of serotonin syndrome. In a patient who requires more urgent treatment of a psychiatric condition, other interventions, including hospitalization, should be considered.
In some cases, a patient already receiving Nortriptyline (Pregabid NT) therapy may require urgent treatment with linezolid or intravenous methylene blue. If acceptable alternatives to linezolid or intravenous methylene blue treatment are not available and the potential benefits of linezolid or intravenous methylene blue treatment are judged to outweigh the risks of serotonin syndrome in a particular patient, Nortriptyline (Pregabid NT) should be stopped promptly, and linezolid or intravenous methylene blue can be administered. The patient should be monitored for symptoms of serotonin syndrome for two weeks or until 24 hours after the last dose of linezolid or intravenous methylene blue, whichever comes first. Therapy with Nortriptyline (Pregabid NT) may be resumed 24 hours after the last dose of linezolid or intravenous methylene blue.
The risk of administering methylene blue by non-intravenous routes (such as oral tablets or by local injection) or in intravenous doses much lower than 1 mg/kg with Nortriptyline (Pregabid NT) is unclear. The clinician should, nevertheless, be aware of the possibility of emergent symptoms of serotonin syndrome with such use.
More about Nortriptyline (Pregabid NT) (Nortriptyline (Pregabid NT))
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Consumer resources
- Nortriptyline (Pregabid NT)
- Nortriptyline (Pregabid NT) Solution
- Nortriptyline (Pregabid NT) (Advanced Reading)
- Other brands: Aventyl Hydrochloride
Professional resources
- Nortriptyline (Pregabid NT) (AHFS Monograph)
- Nortriptyline (Pregabid NT) (FDA)
Related treatment guides
- Depression
- Primary Nocturnal Enuresis
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Nortriptyline (Pregabid NT) interactions
See also:
What other drugs will affect Nortriptyline (Pregabid NT)?
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with this drug include: arbutamine, "blood thinners" (such as warfarin), disulfiram, thyroid supplements, anticholinergic drugs (such as benztropine, belladonna alkaloids), certain drugs for high blood pressure (drugs that work in the brain such as clonidine, guanabenz, reserpine).
Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication. Ask your doctor when to start or stop taking this medication.
The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotonin. Examples include street drugs such as MDMA/"ecstasy," St. John's wort, certain antidepressants (including SSRIs such as fluoxetine/paroxetine, SNRIs such as duloxetine/venlafaxine), among others. The risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs.
Other medications can affect the removal of Nortriptyline (Pregabid NT) from your body, thereby affecting how Nortriptyline (Pregabid NT) works. These drugs include cimetidine, terbinafine, drugs to treat irregular heart rate (such as quinidine/propafenone/flecainide). This is not a complete list.
Many drugs besides Nortriptyline (Pregabid NT) may affect the heart rhythm (QT prolongation in the EKG), including amiodarone, cisapride, dofetilide, pimozide, procainamide, quinidine, sotalol, macrolide antibiotics (such as erythromycin), among others. Therefore, before using Nortriptyline (Pregabid NT), report all medications you are currently using to your doctor or pharmacist.
Tell your doctor or pharmacist if you are taking other products that cause drowsiness, including alcohol, antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants, and narcotic pain relievers (such as codeine).
Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain decongestants or ingredients that cause drowsiness. Ask your pharmacist about using those products safely.
Nortriptyline (Pregabid NT) is very similar to amitriptyline. Do not use medications containing amitriptyline while using Nortriptyline (Pregabid NT).
Nortriptyline (Pregabid NT) side effects
See also:
What are the possible side effects of Nortriptyline (Pregabid NT)?
Applies to Nortriptyline (Pregabid NT): oral capsule, oral solution, oral tablet
As well as its needed effects, Nortriptyline (Pregabid NT) (the active ingredient contained in Nortriptyline (Pregabid NT)) may cause unwanted side effects that require medical attention.
Major Side Effects
If any of the following side effects occur while taking Nortriptyline (Pregabid NT), check with your doctor immediately:
Incidence not known:
- Abdominal or stomach pain
- agitation
- blurred vision
- burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- chest pain or discomfort
- clay-colored stools
- cold sweats
- confusion about identity, place, and time false beliefs that cannot be changed by facts
- continuing ringing or buzzing or other unexplained noise in the ears
- decreased urination
- depression
- difficulty in passing urine (dribbling)
- difficulty with speaking
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- double vision
- fast, pounding, or irregular heartbeat or pulse
- feeling of warmth
- feeling, seeing, or hearing things that are not there
- feeling that others are watching you or controlling your behavior
- feeling that others can hear your thoughts
- general feeling of tiredness or weakness
- hostility
- hyperventilation
- inability to move the arms, legs, or facial muscles
- inability to speak
- irritability
- loss of balance control
- lower back or side pain
- mood or mental changes
- muscle spasm or jerking of all extremities
- muscle trembling, jerking, or stiffness
- nightmares
- pain or discomfort in the arms, jaw, back, or neck
- painful or difficult urination
- panic
- perspiration
- pinpoint red or purple spots on the skin
- redness of the face, neck, arms, and occasionally, upper chest
- restlessness
- seizures
- slurred speech
- sores, ulcers, or white spots on the lips or in the mouth
- stiffness of the limbs
- sweating
- swelling of the face, ankles, legs, or hands
- talking, feeling, and acting with excitement
- trouble sleeping
- twisting movements of the body uncontrolled movements, especially of the face, neck, and back
- weakness in the arms, hands, legs, or feet
Minor Side Effects
Some Nortriptyline (Pregabid NT) side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:
Incidence not known:
- Bigger, dilated, or enlarged pupils (black part of the eye)
- black tongue
- decreased interest in sexual ability or desire
- difficulty having a bowel movement (stool)
- enlargement of the breast
- hair loss or thinning of the hair
- heartburn
- hives or welts
- increase in sexual ability or desire
- increased sensitivity of the eyes or skin to light
- pain or discomfort in the chest, upper stomach, or throat
- peculiar taste
- severe sunburn
- small red or purple spots on the skin
- swelling of the testicles
- swelling or inflammation of the mouth
- swollen, painful, or tender lymph glands on side of face or neck
- vision changes
- waking to urinate at night
Nortriptyline (Pregabid NT) contraindications
See also:
What is the most important information I should know about Nortriptyline (Pregabid NT)?
Monoamine Oxidase Inhibitors (MAOIs)
The use of MAOIs intended to treat psychiatric disorders with Nortriptyline (Pregabid NT) hydrochloride or within 14 days of stopping treatment with Nortriptyline (Pregabid NT) hydrochloride is contraindicated because of an increased risk of serotonin syndrome. The use of Nortriptyline (Pregabid NT) hydrochloride within 14 days of stopping an MAOI intended to treat psychiatric disorders is also contraindicated (seeWARNINGSandDOSAGE AND ADMINISTRATION).
Starting Nortriptyline (Pregabid NT) hydrochloride in a patient who is being treated with MAOIs such as linezolid or intravenous methylene blue is also contraindicated because of an increased risk of serotonin syndrome (seeWARNINGS and DOSAGE AND ADMINISTRATION).
Hypersensitivity to Tricyclic Antidepressants
Cross-sensitivity between Nortriptyline (Pregabid NT) hydrochloride and other dibenzazepines is a possibility.
Myocardial Infarction
Nortriptyline (Pregabid NT) hydrochloride is contraindicated during the acute recovery period after myocardial infarction.
What is Pregabalin (Pregabid NT)?
Pregabalin (Pregabid NT) (Pregabalin (Pregabid NT)) is an anti-epileptic drug, also called an anticonvulsant. Pregabalin (Pregabid NT) works by slowing down nerve impulses in the brain and affects chemicals that send pain signals across the nervous system.
Pregabalin (Pregabid NT) is a prescription medicine used to treat pain caused by damaged nerves in people with diabetes (diabetic neuropathy). Pregabalin (Pregabid NT) is also used to treat pain caused by damaged nerves (neuropathic pain) that follows healing of shingles (herpes zoster). This condition is called post-herpetic neuralgia.
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It is not known if Pregabalin (Pregabid NT) is effective when used for the treatment of fibromyalgia, or when taken with other seizure medicines for adults with partial onset seizures.
Pregabalin (Pregabid NT) is supplied as extended-release tablets in the following strengths: 82.5 mg, 165 mg, and 330 mg.
Pregabalin (Pregabid NT) indications
Neuropathic Pain: Pregabalin (Pregabid NT) is indicated for the treatment of neuropathic pain in adults, including neuropathic pain associated with spinal cord injury.
Epilepsy: Pregabalin (Pregabid NT) is indicated as adjunctive therapy in adults with partial seizures, with or without secondary generalization.
Generalized Anxiety Disorder: Pregabalin (Pregabid NT) is indicated for the treatment of Generalized Anxiety Disorder (GAD) in adults.
Fibromyalgia: Pregabalin (Pregabid NT) is indicated for the management of fibromyalgia.
How should I use Pregabalin (Pregabid NT)?
Use Pregabalin (Pregabid NT) as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Pregabalin (Pregabid NT) comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Pregabalin (Pregabid NT) refilled.
- Take Pregabalin (Pregabid NT) by mouth with or without food.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- Taking Pregabalin (Pregabid NT) at the same time each day will help you remember to take it.
- Take Pregabalin (Pregabid NT) on a regular schedule to get the most benefit from it.
- If you miss a dose of Pregabalin (Pregabid NT), take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Pregabalin (Pregabid NT).
Uses of Pregabalin (Pregabid NT) in details
Use: Labeled Indications
Fibromyalgia (immediate release only): Management of fibromyalgia
Neuropathic pain associated with diabetic peripheral neuropathy (immediate release and extended release): Management of neuropathic pain associated with diabetic peripheral neuropathy
Neuropathic pain associated with spinal cord injury (immediate release only): Management of neuropathic pain associated with spinal cord injury
Postherpetic neuralgia (immediate release and extended release): Management of postherpetic neuralgia
Seizures, focal (partial) onset (immediate release only): Adjunctive therapy in patients ≥1 month of age with focal onset (partial-onset) seizures
Off Label Uses
Cough, chronic refractory
Data from a limited number of patients in a controlled trial suggest that Pregabalin (Pregabid NT) in combination with speech pathology therapy may be beneficial for the treatment of refractory chronic cough.
Based on the American Association of Clinical Endocrinologists (AACE) and American College of Endocrinology (ACE) position statement on menopause, the Endocrine Society guideline on the treatment of symptoms of menopause, and the North American Menopause Society (NAMS) position statement on nonhormonal management of menopause-associated vasomotor symptoms, Pregabalin (Pregabid NT) is an effective and recommended alternative for the management of vasomotor symptoms associated with menopause in patients with contraindications to hormonal therapy or who prefer not to use hormonal therapy.
Pregabalin (Pregabid NT) description
Each capsule contains the following inactive ingredients: Mannitol, maize starch and talc.
Pregabalin (Pregabid NT) is described chemically as (S)-3-(aminomethyl)-5-methylhexanoic acid. The molecular formula is C8H17NO2 and the molecular weight is 159.23.
Pregabalin (Pregabid NT) is a white to off-white, crystalline solid with a pKa1 of 4.2 and a pKa2 of 10.6. It is freely soluble in water and both basic and acidic aqueous solutions. The log of the partition coefficient (n-octanol/0.05 M phosphate buffer) at pH 7.4 is -1.35.
Pregabalin (Pregabid NT) dosage
The dose range is 150 to 600 mg per day given in either two or three divided doses.
Epilepsy: Pregabalin (Pregabid NT) treatment can be started with a dose of 150 mg per day given as two or three divided doses. Based on individual patient response and tolerability, the dose may be increased to 300 mg per day after 1 week. The maximum dose of 600 mg per day may be achieved after an additional week.
Generalised Anxiety Disorder: The dose range is 150 to 600 mg per day given as two or three divided doses. The need for treatment should be reassessed regularly.
Pregabalin (Pregabid NT) treatment can be started with a dose of 150 mg per day. Based on individual patient response and tolerability, the dose may be increased to 300 mg per day after 1 week. Following an additional week, the dose may be increased to 450 mg per day. The maximum dose of 600 mg per day may be achieved after an additional week.
Discontinuation of Pregabalin (Pregabid NT): In accordance with current clinical practice, if Pregabalin (Pregabid NT) has to be discontinued, it is recommended this should be done gradually over a minimum of 1 week independent of the indication.
Patients with Renal Impairment: Pregabalin (Pregabid NT) is eliminated from the systemic circulation primarily by renal excretion as unchanged drug. As Pregabalin (Pregabid NT) clearance is directly proportional to creatinine clearance, dose reduction in patients with compromised renal function must be individualised according to creatinine clearance (CrCl), as indicated in Table 1 determined using the following formula.
Pregabalin (Pregabid NT) is removed effectively from plasma by haemodialysis (50% of drug in 4 hours). For patients receiving haemodialysis, the Pregabalin (Pregabid NT) daily dose should be adjusted based on renal function. In addition to the daily dose, a supplementary dose should be given immediately following every 4-hour haemodialysis treatment.
Patients with Hepatic Impairment: No dose adjustment is required for patients with hepatic impairment.
Children: The safety and efficacy of Pregabalin (Pregabid NT) in children below the age of 12 years and in adolescents (12-17 years of age) have not been established. No data are available.
Elderly (over 65 years of age): Elderly patients may require a dose reduction of Pregabalin (Pregabid NT) due to a decreased renal function.
Administration: Pregabalin (Pregabid NT) may be taken with or without food.
Pregabalin (Pregabid NT) is for oral use only.
Pregabalin (Pregabid NT) interactions
See also:
What other drugs will affect Pregabalin (Pregabid NT)?
Since Pregabalin (Pregabid NT) is predominantly excreted unchanged in the urine, undergoes negligible metabolism in humans (<2% of a dose recovered in urine as metabolites), does not inhibit drug metabolism in vitro and is not bound to plasma proteins, it is unlikely to produce or be subject to pharmacokinetic interactions.
Accordingly, in in vivo studies no clinically relevant pharmacokinetic interactions were observed between Pregabalin (Pregabid NT) and phenytoin, carbamazepine, valproic acid, lamotrigine, gabapentin, lorazepam, oxycodone or ethanol. Population pharmacokinetic analysis indicated that the oral antidiabetics, diuretics, insulin, phenobarbital, tiagabine and topiramate had no clinically significant effect on Pregabalin (Pregabid NT) clearance.
Co-administration of Pregabalin (Pregabid NT) with the oral contraceptives norethisterone and/or ethinyl oestradiol does not influence the steady-state pharmacokinetics of either substance. Pregabalin (Pregabid NT) may potentiate the effects of ethanol and lorazepam. In controlled clinical trials, multiple oral doses of Pregabalin (Pregabid NT) co-administered with oxycodone, lorazepam or ethanol did not result in clinically important effects on respiration. In the post-marketing experience, there are reports of respiratory failure and coma in patients taking Pregabalin (Pregabid NT) and other CNS depressant medications. Pregabalin (Pregabid NT) appears to be additive in the impairment of cognitive and gross motor function caused by oxycodone.
No specific pharmacodynamic interaction studies were conducted in elderly volunteers.
Pregabalin (Pregabid NT) side effects
See also:
What are the possible side effects of Pregabalin (Pregabid NT)?
The Pregabalin (Pregabid NT) clinical program involved over 8900 patients who were exposed to Pregabalin (Pregabid NT), of whom over 5600 were in double-blind placebo-controlled trials. The most commonly reported adverse reactions were dizziness and somnolence. Adverse reactions were usually mild to moderate in intensity. In all controlled studies, the discontinuation rate due to adverse reactions was 12% for patients receiving Pregabalin (Pregabid NT) and 5% for patients receiving placebo. The most common adverse reactions resulting in discontinuation from Pregabalin (Pregabid NT) treatment groups were dizziness and somnolence.
In Table 2 all adverse reactions, which occurred at an incidence greater than placebo and in more than one patient, are listed by class and frequency (very common (≥1/10), common (≥1/100, <1/10), uncommon (≥1/1000, <1/100), rare (≥1/10,000 to <1/1,000); very rare (<1/10,000), not known (cannot be estimated from the available data). Within each frequency grouping, undesirable effects are presented in order of decreasing seriousness.
The adverse reactions listed may also be associated with the underlying disease and/or concomitant medicinal products.
In the treatment of central neuropathic pain due to spinal cord injury the incidence of adverse reactions in general, CNS adverse reactions and especially somnolence was increased.
Additional reactions reported from post-marketing experience are included in italics in Table 2.
After discontinuation of short-term and long-term treatment with Pregabalin (Pregabid NT) withdrawal symptoms have been observed in some patients. The following reactions have been mentioned: insomnia, headache, nausea, anxiety, diarrhoea, flu syndrome, convulsions, nervousness, depression, pain, hyperhidrosis and dizziness, suggestive of physical dependence. The patient should be informed about this at the start of the treatment.
Concerning discontinuation of long-term treatment of Pregabalin (Pregabid NT), data suggest that the incidence and severity of withdrawal symptoms may be dose-related.
Pregabalin (Pregabid NT) contraindications
See also:
What is the most important information I should know about Pregabalin (Pregabid NT)?
You may have thoughts about suicide while taking this medication. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.
Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, insomnia, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.
If you are taking Pregabalin (Pregabid NT) to prevent seizures, keep taking the medication even if you feel fine.
Do not stop using Pregabalin (Pregabid NT) without first talking to your doctor, even if you feel fine. You may have increased seizures or withdrawal symptoms such as headache, sleep problems, nausea, and diarrhea. Ask your doctor how to avoid withdrawal symptoms when you stop using Pregabalin (Pregabid NT).
Do not change your dose of Pregabalin (Pregabid NT) without your doctor's advice. Tell your doctor if the medication does not seem to work as well in treating your condition.
Wear a medical alert tag or carry an ID card stating that you take Pregabalin (Pregabid NT). Any medical care provider who treats you should know that you take seizure medication.
Active ingredient matches for Pregabid NT:
Unit description / dosage (Manufacturer) | Price, USD |
PREGABID NT - 50 TABLET 1 strip / 10 tablets each (Intas Pharmaceuticals Ltd) | $ 1.08 |
PREGABID NT - 75 TABLET 1 strip / 10 tablets each (Intas Pharmaceuticals Ltd) | $ 1.71 |
Pregabid NT - 75 Tablet (Intas Pharmaceuticals Ltd) | $ 0.17 |
List of Pregabid NT substitutes (brand and generic names): | |
Norpregalin Tablet | |
Norpregalin Tablet (Torrent Pharmaceuticals Ltd) | $ 0.16 |
NORTIPAN | |
NORTIPAN 75MG/10MG TABLET 1 strip / 10 tablets each (Medley Pharmaceuticals) | $ 1.81 |
NORTIPAN M 1500MCG/10MG/75MG TABLET 1 strip / 10 tablets each (Medley Pharmaceuticals) | $ 2.05 |
NORTIPAN 75 MG/10 MG TABLET 1 strip / 10 tablets each (Medley Pharmaceuticals) | $ 1.81 |
Nortipan 75 mg/10 mg Tablet (Medley Pharmaceuticals) | $ 0.18 |
Nortriptyline/Pregabalin | |
NORTRYPTOMER P | |
Nortryptomer P 50mg Tablet SR (Wockhardt Ltd) | $ 0.12 |
Nortryptomer P 75mg Tablet SR (Wockhardt Ltd) | $ 0.22 |
NORTRYPTOMER-P (India) | |
NORTRYPTOMER-P SR 50MG TABLET 1 strip / 10 tablets each (Wockhardt) | $ 1.20 |
NORTRYPTOMER-P SR 75MG TABLET 1 strip / 10 tablets each (Wockhardt) | $ 2.17 |
NORTRYPTOMER-P tab 10's (Wockhardt) | $ 2.17 |
NUROGAB NT | |
NUROGAB NT 75/10MG TABLET | |
NUROGAB NT 75/10MG TABLET 1 strip / 10 tablets each (Macleods Pharmaceuticals Pvt Ltd) | $ 1.81 |
NUROGAB-NT (India) | |
NUROGAB-NT tab 10's (Macleods (Procare CV)) | $ 1.81 |
NUROMARK PNT | |
Nuromark Pnt 75mg/10mg Tablet (Unimarck Healthcare Ltd) | $ 0.14 |
NUROMARK-PNT | |
NUROMARK-PNT TABLET 1 strip / 10 tablets each (Unimarck Healthcare Ltd) | $ 1.39 |
Pabanor | |
Pabanor 75mg/10mg Tablet (Staunch Health Care Pvt Ltd) | $ 0.16 |
PBREN NT | |
PBREN NT 75MG/10MG TABLET 1 strip / 10 tablets each (La Renon Healthcare Pvt Ltd) | $ 2.17 |
PEBLIN NT | |
PEBLIN NT 75MG/10MG TABLET 1 strip / 10 tablets each (Mova Pharmaceutical Pvt Ltd) | $ 2.05 |
PICROWIN | |
PICROWIN 75MG/10MG TABLET 1 strip / 10 tablets each (Maverick Pharma Pvt Ltd) | $ 1.75 |
Preega-NT Tablet | |
Preega-NT Tablet (Talent India ) | $ 0.17 |
PREGABA NT | |
PREGABA NT 75 MG/10 MG TABLET 1 strip / 10 tablets each (Unichem Laboratories Ltd) | $ 1.51 |
PREGADOC NT | |
PREGADOC NT 75MG/10MG TABLET 1 strip / 10 tablets each (Lupin Ltd) | $ 1.75 |
Pregaheal NT Tablet | |
Pregaheal NT Tablet (Meracus Pharmaceuticals) | $ 0.17 |
PREGALIFT NT | |
PREGALIFT NT 75 MG/10 MG TABLET 1 strip / 10 tablets each (Linux Laboratories) | $ 1.45 |
PREGALIN NT | |
Pregaloy NT | |
Pregaloy NT 75mg/10mg Tablet (Lloyd Healthcare Pvt Ltd) | $ 0.19 |
PREGAMAX NT | |
PREGANZA NT | |
PREGANZA NT TABLET 1 strip / 10 tablets each (Emcure Pharmaceuticals Ltd) | $ 1.45 |
PREGANZA-NT (India) | |
PREGANZA-NT tab 10's (Emcure) | $ 1.45 |
PREGATOL NT | |
PREGATOL-NT | |
PREGATOL-NT 75MG/10MG TABLET 1 strip / 10 tablets each (J M BIOCEUTICALS) | $ 2.16 |
PRENOP | |
PRENURA NT | |
PRENURA NT TABLET 1 strip / 10 tablets each (Pulse Pharmaceuticals) | $ 1.55 |
Pretyline | |
Pretyline 75mg/10mg Tablet (Carise Pharmaceuticals Pvt Ltd) | $ 0.13 |
PYROPE NT | |
PYROPE NT 75MG/10MG TABLET 1 strip / 10 tablets each (Arinna Lifescience Pvt Ltd) | $ 1.45 |
SENRICA-NT | |
SENSIVAL P | |
SENSIVAL-P | |
SENSIVAL-P 75 MG/10 MG TABLET 1 strip / 10 tablets each (Wallace Pharmaceuticals Pvt Ltd) | $ 1.93 |
WEGALIN NP | |
ZYLIN NT | |
ZYLIN NT 75 MG/10 MG TABLET 1 strip / 10 tablets each (Zydus Cadila) | $ 1.51 |
See 63 substitutes for Pregabid NT |
References
- DailyMed. "PREGABALIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "Pregabalin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- PubChem. "nortriptyline". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Pregabid NT are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Pregabid NT. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yet5 consumers reported price estimates
Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?The below mentioned numbers have been reported by ndrugs.com website users about whether the Pregabid NT drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users | % | ||
---|---|---|---|
Expensive | 3 | 60.0% | |
Not expensive | 2 | 40.0% |
1 consumer reported time for results
To what extent do I have to use Pregabid NT before I begin to see changes in my health conditions?As part of the reports released by ndrugs.com website users, it takes > 3 month and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Pregabid NT. To get the time effectiveness of using Pregabid NT drug by other patients, please click here.
Users | % | ||
---|---|---|---|
> 3 month | 1 | 100.0% |
16 consumers reported age
Users | % | ||
---|---|---|---|
16-29 | 5 | 31.2% | |
30-45 | 4 | 25.0% | |
> 60 | 4 | 25.0% | |
46-60 | 3 | 18.8% |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology