Satric Uses

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What is Satric?

Satric is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Satric belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, Satric will not work for colds, flu, or other virus infections.

Satric is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, Satric is used in certain patients with the following medical conditions:

Satric indications

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Symptomatic Trichomoniasis. Satric Capsules USP 375 mg are indicated for the treatment of T. vaginalis infection in females and males when the presence of the trichomonad has been confirmed by appropriate laboratory procedures (wet smears and/or cultures).

Asymptomatic Trichomoniasis. Satric Capsules USP 375 mg are indicated in the treatment of asymptomatic T. vaginalis infection in females when the organism is associated with endocervicitis, cervicitis, or cervical erosion. Since there is evidence that presence of the trichomonad can interfere with accurate assessment of abnormal cytological smears, additional smears should be performed after eradication of the parasite.

Treatment of Asymptomatic Sexual Partners. T. vaginalis infection is a venereal disease. Therefore, asymptomatic sexual partners of treated patients should be treated simultaneously if the organism has been found to be present, in order to prevent reinfection of the partner. The decision as to whether to treat an asymptomatic male partner who has a negative culture or one for whom no culture has been attempted is an individual one. In making this decision, it should be noted that there is evidence that a woman may become reinfected if her sexual partner is not treated. Also, since there can be considerable difficulty in isolating the organism from the asymptomatic male carrier, negative smears and cultures cannot be relied upon in this regard. In any event, the sexual partner should be treated with Satric in cases of reinfection.

Amebiasis. Satric Capsules USP 375 mg are indicated in the treatment of acute intestinal amebiasis (amebic dysentery) and amebic liver abscess.

In amebic liver abscess, Satric Capsules USP 375 mg therapy does not obviate the need for aspiration or drainage of pus.

Anaerobic Bacterial Infections. Satric Capsules USP 375 mg are indicated in the treatment of serious infections caused by susceptible anaerobic bacteria. Indicated surgical procedures should be performed in conjunction with Satric therapy. In a mixed aerobic and anaerobic infection, antimicrobials appropriate for the treatment of the aerobic infection should be used in addition to Satric Capsules USP 375 mg.

INTRA-ABDOMINAL INFECTIONS, including peritonitis, intra-abdominal abscess, and liver abscess, caused by Bacteroides species including the B. fragilis group (B. fragilis, B. distasonis, B. ovatus, B. thetaiotaomicron, B. vulgatus), Clostridium species, Eubacterium species, Peptococcus species, or Peptostreptococcus species.

SKIN AND SKIN STRUCTURE INFECTIONS caused by Bacteroides species including the B. fragilis group, Clostridium species, Peptococcus species, Peptostreptococcus species, or Fusobacterium species.

GYNECOLOGIC INFECTIONS, including endometritis, endomyometritis, tubo-ovarian abscess, and postsurgical vaginal cuff infection, caused by Bacteroides species including the B. fragilis group, Clostridium species, Peptococcus species, Peptostreptococcus species, or Fusobacterium species.

BACTERIAL SEPTICEMIA caused by Bacteroides species including the B. fragilis group or Clostridium species.

BONE AND JOINT INFECTIONS (as adjunctive therapy) caused by Bacteroides species including the B. fragilis group.

CENTRAL NERVOUS SYSTEM (CNS) INFECTIONS, including meningitis and brain abscess, caused by Bacteroides species including the B. fragilis group.

LOWER RESPIRATORY TRACT INFECTIONS, including pneumonia, empyema, and lung abscess, caused by Bacteroides species including the B. fragilis group.

ENDOCARDITIS caused by Bacteroides species including the B. fragilis group.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Satric Capsules USP 375 mg and other antibacterial drugs, Satric Capsules USP 375 mg should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

How should I use Satric?

Use Satric cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Satric cream.

Uses of Satric in details

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Satric is an antibiotic that is used to treat a wide variety of infections. It works by stopping the growth of certain bacteria and parasites.

This antibiotic treats only certain bacterial and parasitic infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.

Satric may also be used with other medications to treat certain stomach/intestinal ulcers caused by a bacteria (H. pylori).

How to use Satric

Take this medication by mouth as directed by your doctor. To prevent stomach upset, take this medication with food or a full glass of water or milk. The dosage is based on your medical condition and response to treatment.

Antibiotics work best when the amount of medicine in your body is kept at a constant level. Take this drug at evenly spaced intervals.

Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.

Tell your doctor if your condition lasts or gets worse.

Satric description

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Each 100 mL contains Metronidazole USP 500 mg, sodium chloride USP 0.72% w/v, water for injection USP as needed.

Satric injection, USP is a parenteral dosage form of the synthetic antibacterial agent 1-(β-hydroxyethyl)-2-methyl-5-nitroimidazole. The empirical formula is C6H9N3O3 and the molecular weight is 171.15.

Satric injection, USP in 100 mL is a sterile, nonpyrogenic, iso-osmotic, buffered solution of 500 mg Satric, USP, 790 mg sodium chloride, USP, 47.6 mg dried dibasic sodium phosphate, USP and 22.9 mg anhydrous citric acid, USP. Satric injection, USP has an osmolarity of 310 mOsmol/L (calc) and a pH of 5.5 (4.5 to 7).

Satric dosage

Satric Dosage

Generic name: Satric 750mg

Dosage form: tablet, film coated, extended release

See also:

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Bacterial Vaginosis

750 mg once daily by mouth for seven consecutive days.

Satric 750 mg tablets should be taken under fasting conditions, at least one hour before or two hours after meals. The optimum extended-release characteristics of Satric 750 mg are obtained when the drug is taken under fasting conditions.

Satric tablets should not be split, chewed, or crushed.

Dosage Adjustments

Patients Undergoing Hemodialysis

Hemodialysis removes significant amounts of Satric and its metabolites from systemic circulation. The clearance of Satric will depend on the type of dialysis membrane used, the duration of the dialysis session, and other factors. If the administration of Satric cannot be separated from a hemodialysis session, supplementation of Satric dosage following the hemodialysis session should be considered, depending on the patient's clinical situation.

More about Satric (Satric)

Consumer resources

Professional resources

Other formulations

Related treatment guides

Satric interactions

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What other drugs will affect Satric?

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Simultaneous administration of Zol with:

  • antacids that contain aluminum hydroxide, with kolestiraminom slightly decreases absorption of Satric from the gastrointestinal tract;
  • Satric potentiates the effect of indirect anticoagulants;
  • disulfiram may develop acute psychosis and impaired consciousness;
  • lansoprazole possible glossitis, stomatitis and / or the appearance of dark color language; with lithium carbonate - may increase the concentration of lithium in blood plasma and the development of symptoms of intoxication with prednisone - increased excretion of Satric from the body by accelerating its metabolism in the liver under the influence of prednisone. It is possible a decrease the effectiveness of Zol.
  • rifampicin increased the clearance of Satric from the body, with phenytoin - it is perhaps a slight increase in the concentration of phenytoin in blood plasma, described the case of toxic action;
  • phenobarbital significantly increased excretion of Satric from the body, apparently due to acceleration of its metabolism in the liver under the influence of phenobarbital. It is possible a decrease the effectiveness of Zol;
  • fluorouracil enhanced the toxic effect but not the effectiveness of fluorouracil;
  • cimetidine may inhibit the metabolism of Satric in the liver that can lead to slow its elimination and increase the concentration in blood plasma. It can not be excluded the increase in the concentration of carbamazepine in plasma and increased risk of toxicity with concomitant use of Zol. There was described a case of acute dystonia after a single dose of chloroquine in patients treated with Satric.

    Satric side effects

    See also:
    What are the possible side effects of Satric?

    In a controlled clinical trial, safety data from 141 patients who used Satric Lotion

    Topical Lotion (n=71), or the lotion vehicle (n=70), twice daily and experienced a local cutaneous adverse event which may or may not have been related to the treatments include: local allergic reaction, Satric

    Topical Lotion 2 (3%), lotion vehicle 0; contact dermatitis, Satric Lotion

    Topical Lotion 2 (3%), lotion vehicle 1 (1%); pruritus, Satric Lotion

    Topical Lotion 1 (1%), lotion vehicle 0; skin discomfort (burning and stinging), Satric Lotion

    Topical Lotion 1 (1%), lotion vehicle 2 (3%); erythema, Satric Lotion

    Topical Lotion 4 (6%), lotion vehicle 0; dry skin, Satric Lotion

    Topical Lotion 0, lotion vehicle 1 (1%); and worsening of rosacea, Satric Lotion

    Topical Lotion 1 (1%), lotion vehicle 7 (10%).

    The following additional adverse experiences have been reported with the topical use of Satric: skin irritation, transient redness, metallic taste, tingling or numbness of extremities, and nausea.

    Satric contraindications

    See also:
    What is the most important information I should know about Satric?

    Hypersensitivity

    Satric Capsules 375 mg are contraindicated in patients with a prior history of hypersensitivity to Satric or other nitroimidazole derivatives.

    In patients with trichomoniasis, Satric Capsules 375 mg are contraindicated during the first trimester of pregnancy.

    Psychotic Reaction with Disulfiram

    Use of oral Satric is associated with psychotic reactions in alcoholic patients who were using disulfiram concurrently. Do not administer Satric to patients who have taken disulfiram within the last two weeks.

    Interaction with Alcohol

    Use of oral Satric is associated with a disulfiram-like reaction to alcohol, including abdominal cramps, nausea, vomiting, headaches, and flushing. Discontinue consumption of alcohol or products containing propylene glycol during and for at least three days after therapy with Satric.

    Active ingredient matches for Satric:

    Metronidazole in India.

    Allopurinol in India.


    Unit description / dosage (Manufacturer)Price, USD
    Tablet; Oral; Metronidazole 250 mg
    Tablet; Oral; Metronidazole 500 mg
    100 mg x 100's$ 2.89
    Satric 100mg TAB / 100$ 2.89
    Satric 100 mg Tablet$ 0.03
    SATRIC tab 100 mg x 10's (Zytras)$ 0.29

    List of Satric substitutes (brand and generic names):

    Sarnomet 30 ml Suspension (Sarthak Biotech Pvt. Ltd.)$ 0.05
    Say O Flox M 30 ml Suspension (Sayona Medicare Pvt Ltd)$ 0.06
    Seloric 100 mg Tablet (Mefro Pharmaceuticals Pvt Ltd)$ 0.02
    Septigard Skin 10 gm Ointment (Vanguard Laboratories)$ 0.31
    SEPTIGARD 1%/5% OINTMENT 1 tube / 15 GM ointment each (Vanguard Laboratories)$ 0.80
    SEPTIGARD DUSTING POWDER 1 packet / 10 GM dusting powder each (Vanguard Laboratories)$ 0.32
    SEPTIGARD OINTMENT 1 tube / 10 GM ointment each (Vanguard Laboratories)$ 0.42
    SEPTIGARD SOLUTION 1 bottle / 30 ML solution each (Vanguard Laboratories)$ 0.35
    SEPTIGARD oint 10g (Vanguard Laboratories)$ 0.31
    Septigard 1%/5% Ointment (Vanguard Laboratories)$ 0.05
    Septigard 5% w/v Solution (Vanguard Laboratories)$ 0.35
    Septigard Dusting Powder (Vanguard Laboratories)$ 0.32
    Dragee; Oral; Metronidazole (Novartis)
    Suspension; Oral; Metronidazole Benzoate (Novartis)
    Tablet; Oral; Metronidazole (Novartis)
    Servizol 200 mg/5 mL x 60 mL (Novartis)$ 2.79
    Servizol 500 mg/100 mL x 1's (Novartis)$ 5.75
    Injectable; Infusion; Metronidazole Benzoate 5 mg / ml (Novartis)
    Suspension; Oral; Metronidazole Benzoate 200 mg / 5 ml (Novartis)
    Tablets; Oral; Metronidazole (Novartis)
    Sinoric 100 mg x 6 x 10's (Mersifarma TM)$ 2.72
    Sinoric 300 mg x 3 x 10's (Mersifarma TM)$ 3.72
    Siptrogyl 5 % x 1 Bottle 100 mL
    Suspension; Oral; Metronidazole Benzoate (Diba)
    Tablet; Oral; Metronidazole (Diba)
    Tablets; Oral; Metronidazole (Diba)
    Sonamizole 400 mg Tablet (Smith Stanistreet Pharmaceuticals Ltd.)$ 0.01
    100 mg x 10's (Gopal Life Sciences (Sovia Altis))$ 0.33
    Soviric 100mg TAB / 10 (Gopal Life Sciences (Sovia Altis))$ 0.33
    Soviric 100 mg Tablet (Gopal Life Sciences (Sovia Altis))$ 0.03
    SOVIRIC tab 100 mg x 10's (Gopal Life Sciences (Sovia Altis))$ 0.33

    References

    1. DailyMed. "BISMUTH SUBCITRATE POTASSIUM; METRONIDAZOLE; TETRACYCLINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
    2. DailyMed. "ALLOPURINOL; LESINURAD: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
    3. PubChem. "metronidazole". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

    Reviews

    The results of a survey conducted on ndrugs.com for Satric are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Satric. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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    Information checked by Dr. Sachin Kumar, MD Pharmacology

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