Surantel P Uses

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What is Surantel P?

Surantel P belongs to the family of medicines called anthelmintics. Anthelmintics are used in the treatment of worm infections.

Surantel P is used to treat pinworms (enterobiasis; oxyuriasis).

Surantel P may also be used for other worm infections as determined by your doctor.

Surantel P works by paralyzing the worms. They are then passed in the stool.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, Surantel P is used in certain patients with the following medical condition:

For patients taking Surantel P for hookworm infection :

Surantel P indications

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Oral

Single or mixed infections due to susceptible worms

Adult: 10 mg/kg as a single dose.

Child: 10 mg/kg as a single dose.

Oral

Ascariasis

Adult: 5 mg/kg as a single dose. Max: 1 g/dose. For mass treatment programmes: 2.5 mg/kg as a single dose given 3-4 times a yr.

Oral

Necatoriasis

Adult: 10 mg/kg daily for 3-4 days or 20 mg/kg daily for 2 days.

Oral

Enterobiasis

Adult: 10 mg/kg repeated once after 2-4 wk. Max dose: 1 g/dose.

Oral

Trichinosis

Adult: 10 mg/kg daily for 5 days.

How should I use Surantel P?

Use Surantel P as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Surantel P.

Surantel P description

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Surantel P is an antinematodal thiophene

Surantel P dosage

Surantel P Dosage

Applies to the following strength(s): 144 mg/mL; 180 mg; 50 mg/mL

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Enterobiasis

11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.

Usual Adult Dose for Pinworm Infection (Enterobius vermicularis)

11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.

Usual Adult Dose for Hookworm Infection (Necator or Ancylostoma)

11 mg/kg base (maximum 1 g) orally daily for 3 days.

Usual Adult Dose for Ascariasis

11 mg/kg base (maximum 1 g) orally once.

Usual Adult Dose for Trichostrongylosis

11 mg/kg base (maximum 1 g) orally once.

Usual Adult Dose for Moniliformis Infection

11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.

Usual Pediatric Dose for Enterobiasis

>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.

Usual Pediatric Dose for Pinworm Infection (Enterobius vermicularis)

>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.

Usual Pediatric Dose for Hookworm Infection (Necator or Ancylostoma)

>=2 years: 11 mg/kg base (maximum 1 g) orally daily for 3 days.

Usual Pediatric Dose for Ascariasis

>=2 years: 11 mg/kg base (maximum 1 g) orally once.

Usual Pediatric Dose for Trichostrongylosis

>=2 years: 11 mg/kg base (maximum 1 g) orally once.

Usual Pediatric Dose for Moniliformis Infection

>=2 years: 11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Surantel P is contraindicated in patients with hepatic disease.

Dose Adjustments

In the treatment of ascariasis, Surantel P may be used only if it has been determined that the worm load will not worsen obstruction.

Precautions

Surantel P is contraindicated in patients with hepatic disease.

When one individual in a household has pinworms, the entire household should be treated unless otherwise advised. Pinworm infections are easily transmitted to others in the same household.

Surantel P should be used with caution in patients with severe malnutrition or anemia. Supportive therapy is recommended for anemic, dehydrated, or malnourished patients prior to administration of the drug.

Other medications are known to antagonize the anthelmintic effect of Surantel P. Patients should be advised to consult with their physician before initiating any drug therapy while receiving Surantel P.

Dialysis

Data not available

Other Comments

The dose should be taken as a single oral dose. It may be taken alone or with milk or fruit juice.

Surantel P pamoate 2.9 g is approximately equivalent to 1 g of Surantel P (base).

More about Surantel P

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Surantel P interactions

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What other drugs will affect Surantel P?

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• Dexamethasone

Steady-state trough concentrations of albendazole sulfoxide were about 56% higher when 8 mg dexamethasone was coadministered with each dose of albendazole (15 mg/kg/day) in 8 neurocysticercosis patients.

• Praziquantel

• Cimetidine

Albendazole sulfoxide concentrations in bile and cystic fluid were increased (about 2-fold) in hydatid cyst patients treated with cimetidine (10 mg/kg/day) (n = 7) compared with albendazole (20 mg/kg/day) alone (n = 12). Albendazole sulfoxide plasma concentrations were unchanged 4 hours after dosing.

• Theophylline

The pharmacokinetics of theophylline (aminophylline 5.8 mg/kg infused over 20 minutes) were unchanged following a single oral dose of albendazole (400 mg) in 6 healthy subjects.

Surantel P side effects

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What are the possible side effects of Surantel P?

Applies to Surantel P: oral suspension, oral tablet, oral tablet chewable

In addition to its needed effects, some unwanted effects may be caused by Surantel P (the active ingredient contained in Surantel P). In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Surantel P, check with your doctor or nurse as soon as possible:

Rare

Minor Side Effects

Some of the side effects that can occur with Surantel P may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:

Surantel P contraindications

See also:
What is the most important information I should know about Surantel P?

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This medicine is contraindicated in patients with known hypersensitivity to the benzimidazole class of compounds or any components of this medicine.

Active ingredient matches for Surantel P:

Pyrantel in United Kingdom.


List of Surantel P substitutes (brand and generic names)

Sort by popularity
Unit description / dosage (Manufacturer)Price, USD
Drug Premix; Oral; Pyrantel Tartrate 10.6 g / kg
Paste; Oral; Pyrantel Pamoate 3.58 g
Suspension; Oral; Pyrantel Pamoate 50 mg / ml
Thelmex 250mg TAB / 3 (BPL Pharmaceuticals (P) Ltd.)$ 0.14
Thelmex 200mg x 5mL SUSP / 8 (BPL Pharmaceuticals (P) Ltd.)$ 0.10
Thelmex 250 mg Tablet (BPL Pharmaceuticals (P) Ltd.)$ 0.05
Thelmex 10 ml Suspension (BPL Pharmaceuticals (P) Ltd.)$ 0.05
THELMEX tab 250 mg x 3's (BPL Pharmaceuticals (P) Ltd.)$ 0.14
THELMEX oral susp 200 mg x 5 mL x 10ml (BPL Pharmaceuticals (P) Ltd.)$ 0.10
Tolworm 10 ml Suspension (Tosc International Pvt Ltd.)$ 0.01

References

  1. PubChem. "PYRANTEL". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Pyrantel". http://www.drugbank.ca/drugs/DB11156 (accessed September 17, 2018).
  3. MeSH. "Antinematodal Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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