What is Pyrantel?
Pyrantel belongs to the family of medicines called anthelmintics. Anthelmintics are used in the treatment of worm infections.
Pyrantel is used to treat pinworms (enterobiasis; oxyuriasis).
Pyrantel may also be used for other worm infections as determined by your doctor.
Pyrantel works by paralyzing the worms. They are then passed in the stool.
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, Pyrantel is used in certain patients with the following medical condition:
- Common roundworm infection
- Hookworm infection
- More than one worm infection at a time
For patients taking Pyrantel for hookworm infection :
- Anemia (iron-poor blood) may occur in patients with hookworm infections. Therefore, your doctor may want you to take iron supplements to help clear up the anemia. If so, it is important to take iron every day while you are being treated for hookworms. Do not miss any doses. Your doctor may also want you to keep taking iron supplements for up to 6 months after you stop taking Pyrantel. If you have any questions about this, check with your doctor.
Pyrantel indications
Oral
Single or mixed infections due to susceptible worms
Adult: 10 mg/kg as a single dose.
Child: 10 mg/kg as a single dose.
Oral
Ascariasis
Adult: 5 mg/kg as a single dose. Max: 1 g/dose. For mass treatment programmes: 2.5 mg/kg as a single dose given 3-4 times a yr.
Oral
Necatoriasis
Adult: 10 mg/kg daily for 3-4 days or 20 mg/kg daily for 2 days.
Oral
Enterobiasis
Adult: 10 mg/kg repeated once after 2-4 wk. Max dose: 1 g/dose.
Oral
Trichinosis
Adult: 10 mg/kg daily for 5 days.
How should I use Pyrantel?
Use Pyrantel as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Pyrantel may be taken on an empty stomach or with food, milk, or juice.
- Shake well before using a dose of Pyrantel.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- Wear tight underwear both day and night while taking Pyrantel.
- Pyrantel is usually prescribed as a single dose.
- Only one dose of Pyrantel is required. If you forget to take Pyrantel, take it as soon as you remember.
Ask your health care provider any questions you may have about how to use Pyrantel.
Pyrantel description
Pyrantel is an antinematodal thiophene
Pyrantel dosage
Pyrantel Dosage
Applies to the following strength(s): 144 mg/mL; 180 mg; 50 mg/mL
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual Adult Dose for:
- Enterobiasis
- Pinworm Infection (Enterobius vermicularis)
- Hookworm Infection (Necator or Ancylostoma)
- Ascariasis
- Trichostrongylosis
- Moniliformis Infection
Usual Pediatric Dose for:
- Enterobiasis
- Pinworm Infection (Enterobius vermicularis)
- Hookworm Infection (Necator or Ancylostoma)
- Ascariasis
- Trichostrongylosis
- Moniliformis Infection
Additional dosage information:
- Renal Dose Adjustments
- Liver Dose Adjustments
- Dose Adjustments
- Precautions
- Dialysis
- Other Comments
Usual Adult Dose for Enterobiasis
11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.
Usual Adult Dose for Pinworm Infection (Enterobius vermicularis)
11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.
Usual Adult Dose for Hookworm Infection (Necator or Ancylostoma)
11 mg/kg base (maximum 1 g) orally daily for 3 days.
Usual Adult Dose for Ascariasis
11 mg/kg base (maximum 1 g) orally once.
Usual Adult Dose for Trichostrongylosis
11 mg/kg base (maximum 1 g) orally once.
Usual Adult Dose for Moniliformis Infection
11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.
Usual Pediatric Dose for Enterobiasis
>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.
Usual Pediatric Dose for Pinworm Infection (Enterobius vermicularis)
>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.
Usual Pediatric Dose for Hookworm Infection (Necator or Ancylostoma)
>=2 years: 11 mg/kg base (maximum 1 g) orally daily for 3 days.
Usual Pediatric Dose for Ascariasis
>=2 years: 11 mg/kg base (maximum 1 g) orally once.
Usual Pediatric Dose for Trichostrongylosis
>=2 years: 11 mg/kg base (maximum 1 g) orally once.
Usual Pediatric Dose for Moniliformis Infection
>=2 years: 11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Pyrantel is contraindicated in patients with hepatic disease.
Dose Adjustments
In the treatment of ascariasis, Pyrantel may be used only if it has been determined that the worm load will not worsen obstruction.
Precautions
Pyrantel is contraindicated in patients with hepatic disease.
When one individual in a household has pinworms, the entire household should be treated unless otherwise advised. Pinworm infections are easily transmitted to others in the same household.
Pyrantel should be used with caution in patients with severe malnutrition or anemia. Supportive therapy is recommended for anemic, dehydrated, or malnourished patients prior to administration of the drug.
Other medications are known to antagonize the anthelmintic effect of Pyrantel. Patients should be advised to consult with their physician before initiating any drug therapy while receiving Pyrantel.
Dialysis
Data not available
Other Comments
The dose should be taken as a single oral dose. It may be taken alone or with milk or fruit juice.
Pyrantel 2.9 g is approximately equivalent to 1 g of Pyrantel (base).
More about Pyrantel
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Support Group
- En Espanol
- 4 Reviews - Add your own review/rating
Consumer resources
- Pyrantel chewable tablets
- Pyrantel
- Pyrantel suspension
- Pyrantel
- Pyrantel (Advanced Reading)
- Other brands: Pin-X, Pinworm Medicine, Reese's Pinworm Medicine, Pinworm Caplets, More (2) »
Professional resources
- Pyrantel (AHFS Monograph)
Related treatment guides
- Pinworm Infection (Enterobius vermicularis)
- Hookworm Infection (Necator or Ancylostoma)
- Ascariasis
- Enterobiasis
- Moniliformis Infection
- More (1) »
Pyrantel interactions
See also:
What other drugs will affect Pyrantel?
• Dexamethasone
Steady-state trough concentrations of albendazole sulfoxide were about 56% higher when 8 mg dexamethasone was coadministered with each dose of albendazole (15 mg/kg/day) in 8 neurocysticercosis patients.
• Praziquantel
• Cimetidine
Albendazole sulfoxide concentrations in bile and cystic fluid were increased (about 2-fold) in hydatid cyst patients treated with cimetidine (10 mg/kg/day) (n = 7) compared with albendazole (20 mg/kg/day) alone (n = 12). Albendazole sulfoxide plasma concentrations were unchanged 4 hours after dosing.
• Theophylline
The pharmacokinetics of theophylline (aminophylline 5.8 mg/kg infused over 20 minutes) were unchanged following a single oral dose of albendazole (400 mg) in 6 healthy subjects.
Pyrantel side effects
See also:
What are the possible side effects of Pyrantel?
Applies to Pyrantel: oral suspension, oral tablet, oral tablet chewable
In addition to its needed effects, some unwanted effects may be caused by Pyrantel (the active ingredient contained in Pyrantel). In the event that any of these side effects do occur, they may require medical attention.
Severity: Moderate
If any of the following side effects occur while taking Pyrantel, check with your doctor or nurse as soon as possible:
Rare
- Skin rash
Minor Side Effects
Some of the side effects that can occur with Pyrantel may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
Less common:
- Abdominal or stomach cramps or pain
- diarrhea
- dizziness
- drowsiness
- headache
- irritability
- loss of appetite
- nausea or vomiting
- trouble in sleeping
Pyrantel contraindications
See also:
What is the most important information I should know about Pyrantel?
This medicine is contraindicated in patients with known hypersensitivity to the benzimidazole class of compounds or any components of this medicine.
Active ingredient matches for Pyrantel:
Pyrantel
Unit description / dosage (Manufacturer) | Price, USD |
Suspension; Oral; Pyrantel Pamoate 250 mg / 5 ml | |
Tablet; Oral; Pyrantel Pamoate 250 mg | |
Suspension; Oral; Pyrantel 250 mg / 5 ml | |
Tablet; Oral; Pyrantel 250 mg | |
Suspension; Oral; Pyrantel Embonate 250 mg / 5 ml | |
List of Pyrantel substitutes (brand and generic names): | |
Pyran | |
Tablet; Oral; Pyrantel Pamoate 125 mg | |
Pyrantel 125 | |
Pyrantel Chewable Tablets | |
Pyrantel Indo Farma (Indonesia) | |
Pyrantel Pamoate | |
Pyrantel Pamoate Farnam (United States) | |
Pyrantel Pamoate Suspension | |
Pyrantel Pamoato (Italy) | |
Pyrantel Paste (Germany) | |
Pyrantel Pharimexco (Vietnam) | |
Pyrantel Pharimexco 125 mg x 10 Blister x 10 Tablet | |
Pyrantel Pharimexco 125 mg x 1 Bottle 100 Tablet | |
Pyrantel Polpharma (Georgia, Latvia) | |
Pyrantel Sine (China) | |
Pyrantel Vetos-Farma dla kotow For cats (Poland) | |
Pyrantel Vetos-Farma dla psow For dogs (Poland) | |
Pyrantelum (Latvia, Poland) | |
Pyrantelum Medana (Latvia) | |
Pyrantelum Medana / / höông vò mô 250 mg/5 mL x 1 Bottle 15 mL in duïng cuï ñong coù chia vaïch | |
Pyrantelum Polpharma (Poland) | |
Pyrantesan (Poland) | |
Pyrantin (Sri Lanka, Tunisia) | |
Pyrantverm (Poland) | |
Pyrapam (Thailand) | |
Pyrapam 125 mg x 1, 000's (General Drugs House) | |
Pyrapam 50 mg/1 mL x 10 mL (General Drugs House) | |
Pyrapam oral susp 50 mg/mL 10 mL x 1's (General Drugs House) | |
Pyrapam tab 125 mg 1000's (General Drugs House) | |
Pyratape (Ireland, United Kingdom) | |
Pyraverm 125 | |
Pyraverm 250 | |
Pyrequan | |
Pyteldon (Thailand) | |
Pyteldon 125 mg x 100's | |
Pyteldon 250 mg/5 mL x 10 mL x 12's | |
Q.T. Ban Tech (United States) | |
Quantrel (Colombia, Peru, Philippines) | |
Quantrel 10 mL (Johnson & Johnson) | $ 3.57 |
Quantrel oral susp 10 mL x 1's (Johnson & Johnson) | $ 3.57 |
Reese’s Pinworm | |
Reese's Pinworm (United States) | |
Reese's Pinworm Medicine | |
Reese's Pinworm Medicine Suspension | |
RFD (United States) | |
Runcid (Germany) | |
Sepantel (Finland, France, Netherlands) | |
Strongid (Finland, France, Ireland, Italy, Netherlands, Portugal, Switzerland, United Kingdom, United States) | |
See 335 substitutes for Pyrantel |
References
- PubChem. "PYRANTEL". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Pyrantel". http://www.drugbank.ca/drugs/DB11156 (accessed September 17, 2018).
- MeSH. "Antinematodal Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Pyrantel are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Pyrantel. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
1 consumer reported useful
Was the Pyrantel drug useful in terms of decreasing the symptom or the disease?According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
Users | % | ||
---|---|---|---|
Useful | 1 | 100.0% |
Consumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yet1 consumer reported age
Users | % | ||
---|---|---|---|
1-5 | 1 | 100.0% |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology