Surgam SR Uses

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Surgam SR indications

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Surgam SR is indicated for the treatment of:

  • depression
  • panic
  • anxiety disorders
  • obsessive compulsive disorder
  • PSTD or post traumatic stress disorder
  • PMDD or premenstrual dysphoric disorder
  • social phobia

    This medication may also be used for other medical purposes not stated herein.

    Surgam SR description

    Surgam SR is a non-steroidal anti-inflammatory drug of the arylpropionic acid (profen) class, used to treat pain, especially arthritic pain.

    Surgam SR dosage

    When you order Surgam SR, it should be taken exactly as prescribed by your doctor. Each tablet must be taken with a full glass of water.

    For the oral concentrate of this medicine, it must be diluted before taking a dose. A dropper must adequately measure the amount of liquid to be diluted on the oral concentrate.

    Each dose of sertraline should be taken at around the same time each day.

    This drug can be taken with or without food.

    Sertraline is usually taken once a day and at the same time of each day. For the complete and exact dosage, refer to your doctor as other factors may also be considered such as body weight, age and the degree of illness.

    When a dose of Surgam SR is missed, it is advisable to skip that dose and proceed to the next one. However, if the next dosage is many hours away, you could take the missed dose. It is not advisable to take the missed dose of this medication if you are near the time for the next dose, it is best if you entirely skip that dose and wait for the schedule of the next one.

    Surgam SR interactions

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    Never take Surgam SR if you are taking:

  • monoamine oxidase inhibitor (MAOI)
  • pimozide - dangerous reactions could result
  • disulfiram Tell your doctor if you are taking the following drugs:
  • benzodiazepine
  • tricyclic antidepressants
  • phenothiazine
  • lithium
  • almotriptan
  • carbamazepine
  • warfarin
  • digoxin
  • cimetidine
  • bupropion You may be advised to lower your dosage or to entirely stop this medication.

    Surgam SR side effects

    Gastrointestinal:

    Were usually reported gastrointestinal disturbances such as nausea, diarrhea, vomiting, epigastric pain, bowel dysfunction, ulcers, perforations, hemorrhagic colitis, ulcers with or without gastrointestinal bleeding, occult blood or not. These are more frequent than the dose used is high and prolonged treatment and require immediate discontinuation of treatment.

    Hypersensitivity reactions:

    Dermatological: rash, urticaria and exacerbation of chronic urticaria, pruritus, purpura. Rare cases of erythema multiforme and bullous eruptions (Stevens-Johnson syndrome and toxic epidermal necrolysis) requiring immediate discontinuation of treatment. Unique opportunity to photosensitization.

    Respiratory: the occurrence of asthma may be linked in some people an allergy to aspirin or NSAIDs.

    General: general malaise and hypotension, angioedema, anaphylactic shock.

    Effects on the central nervous system:

    Dizziness, rare.

    Renal:

    Fluid retention, hyperkalemia.

    Acute renal failure (ARF) function in patients with risk factors.

    Kidney organics can lead to IRA: isolated cases of interstitial nephritis, acute tubular necrosis, nephrotic syndrome, papillary necrosis have been reported.

    Urinary: urinary (cystalgie, dysuria and urinary frequency), hematuria or cystitis may occur. Severe cases have been exceptionally reported when treatment was continued. These disorders are reversible upon discontinuation of treatment.

    Other

    Exceptionally, occurrence of serious infectious complications skin and soft tissue during varicella.

    Changes in biological

    exceptional, abnormal liver tests,

    thrombocytopenia.

    Surgam SR contraindications

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    History of allergy or asthma triggered by taking Surgam SR or substances of similar activity such as other NSAIDs, aspirin,

    - History of allergy to other constituents of the tablet,

    - Peptic ulcer evolving

    - Severe liver failure,

    - Renal failure,

    - Severe heart failure uncontrolled

    - Children under 15 kg, approximately less than 4 years (because of the inadequate dosing unit)

    - Beyond 24 weeks of gestation (age 5 months of pregnancy):

    administration in the 2nd and 3rd quarters exposes: renal functional impairment may occur in utero from 12 weeks of gestation (start of fetal diuresis): trace amnion (usually reversible with the discontinuation), or anamnios especially during a prolonged exposure, at birth, renal failure (reversible or not) can persist especially if late and prolonged exposure (with a risk of severe hyperkalemia delayed) and a risk of harm cardiopulmonary constriction partial or complete in utero ductus arteriosus. The constriction of the ductus arteriosus may occur from 5 months of age and can lead to right heart failure or fetal or neonatal fetal death in utero. This risk is even more important that the outlet is near term (less reversibility). This effect exists even for a timely decision, a risk of prolongation of bleeding time for mother and child. Therefore, beyond 24 weeks of gestation (5 months old): any point is made even cons-indicated. An inadvertently fly beyond 24 weeks of gestation (5 months of age) warrants monitoring cardiac and kidney, fetal and / or neonatal exposure by term. The duration of this monitoring will be adapted to the half-life of the molecule.



    Active ingredient matches for Surgam SR:

    Tiaprofenic Acid


    Unit description / dosage (Manufacturer)Price, USD
    Capsule, Sustained Release; Oral; Tiaprofenic Acid 300 mg
    Surgam SR capsule / sustained-release 300 mg (Sanofi Aventis Canada Inc (Canada))

    List of Surgam SR substitutes (brand and generic names):

    Suroten 200 mg
    Sutain 200 mg
    Tia Ton 200 mg
    Tiap 200 mg x 1000's
    Tablet; Oral; Tiaprofenic Acid 200 mg
    Tablet; Oral; Tiaprofenic Acid 300 mg
    Apo-Tiaprofenic 300 mg Tablet$ 0.43
    Novo-Tiaprofenic 300 mg Tablet$ 0.43
    Nu-Tiaprofenic 300 mg Tablet$ 0.43
    Apo-Tiaprofenic 200 mg Tablet$ 0.36
    Novo-Tiaprofenic 200 mg Tablet$ 0.36
    Apo-Tiaprofenic 300 mg Tablet$ 0.43
    Novo-Tiaprofenic 300 mg Tablet$ 0.43
    Nu-Tiaprofenic 300 mg Tablet$ 0.43
    Apo-Tiaprofenic 200 mg Tablet$ 0.36
    Novo-Tiaprofenic 200 mg Tablet$ 0.36
    Tiaprofenic-200 - Tab tablet 200 mg (Pro Doc Limitee (Canada))
    Tiaprofenic-300 - Tab tablet 300 mg (Pro Doc Limitee (Canada))
    Tablet; Oral; Tiaprofenic Acid 100 mg
    Tifenic 200 mg
    Tiogam 200 mg
    Tiopen 200 mg x 500's
    Tiopen 200 mg x 1000's
    Tiprofen 200 mg
    Trobenide 300 mg x 3 Blister x 10 Tablet
    User 25mg TAB / 10 (Triton)
    User 50mg TAB / 10 (Triton)

    References

    1. PubChem. "tiaprofenic acid". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
    2. DrugBank. "tiaprofenic acid". http://www.drugbank.ca/drugs/DB01600 (accessed September 17, 2018).
    3. MeSH. "Anti-Inflammatory Agents, Non-Steroidal". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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    Information checked by Dr. Sachin Kumar, MD Pharmacology

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