Tremarit Uses

How do you administer this medicine?
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Tremarit indications

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Oral

As monotherapy in Parkinson's disease

Adult: As hydrochloride: Initially, 2.5 mg tid; increase gradually depending on clinical response to a total of 15-60 mg daily in divided doses.

Tremarit description

Tremarit (or methixene) is a anticholinergic used as an anti-parkinson drug.

Tremarit dosage

Oral

As monotherapy in Parkinson's disease

Adult: As hydrochloride: Initially, 2.5 mg tid; increase gradually depending on clinical response to a total of 15-60 mg daily in divided doses.

Tremarit interactions

The association with other psychoactive drugs requires special caution and vigilance by the physician to avoid unexpected side effects from interaction. n particular, when administered concomitantly with a phenothiazine Tremarit, must not exceed the total daily dose of 15 mg.

Tremarit side effects

Early treatment may experience constipation, nausea, dry mouth, dizziness, tachycardia, mild visual problems, a sense of excitement: these events usually disappear with the progress of treatment.

However, if they persist, you should gradually reduce the dose up to a limit well tolerated, maintained for a certain period of time and then increase again with caution.

Half an hour to one hour after administration of a single dose of 10-15 mg may occur nausea, abdominal distension, weakness, fatigue.

Signs of confusion may occur especially in patients treated with high doses of the product administered in combination with other medications. If these signs occur you need to stop treatment.

Tremarit contraindications

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Tremarit 5mg tablets should not be taken at:

Known hypersensitivity to the drug and / or to any of other ingredients.

Acute poisoning with hypnotics analgesics tricyclic antidepressants, anticonvulsant drugs (antispasmodics), means for allergy (antihistamine), psychotropic drugs and alcohol.

Untreated glaucoma (angle closure glaucoma)

Constipation (intestinal atony).

Mechanical narrowing (stenosis) in the area of the gastro-intestinal tract.

Colon extensions (megacolon).

On suspicion of starting an existing memory or dementia. Should a suspicion exist, it must be her doctor a special test (Mini-Mental State Examination [MMSE] conduct) to eliminate the relevant suspicion.

Active ingredient matches for Tremarit:

Metixene in Germany.

Metixene hydrochloride in Germany.


List of Tremarit substitutes (brand and generic names)

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References

  1. DailyMed. "METHIXENE HYDROCHLORIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "Metixene". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "Metixene". http://www.drugbank.ca/drugs/DB00340 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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