Zolidime Uses

Rating: 3.75 - 4 review(s)
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Zolidime indications

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To aid in the treatment of rheumatism.

this medicine should only be administered when other NSAIDs have not produced satisfactory results and only against acute outbreaks of the following conditions:

* Ankylosing spondylitis.

* Gout.

* Rheumatoid arthritis.

* Osteoarthritis.

Zolidime interactions

this medicine can increase the activity, the duration of the effect and toxicity of oral anticoagulants (risk of bleeding), the oral agents (risk of serious hypoglycemia) of insulin, phenytoin, sodium valproate, lithium, methotrexate and sulfonamides. this medicine can induce hepatic microsomal metabolism of dicumarol, digitoxin, hexobarbital and cortisone. Inducers of hepatic microsomal enzymes, eg barbiturates, promethazine, chlorpheniramine, rifampicin and corticosteroids (prednisone) may shorten the average life of this medicine.

Conversely, methylphenidate has been reported to prolong the lifetime of this medicine and increases the serum concentration of oxyphenbutazone. Concomitant administration of this medicine with other NSAIDs or corticosteroids increases the risk of causing serious gastrointestinal adverse reactions. Administered together, this medicine and misoprostol can induce adverse symptoms related to central nervous system such as dizziness, headache and transient diplopia.

this medicine may potentiate the effects of alcohol on the central nervous system.

Cholestyramine and antacids reduce this medicine enteral resorption. During concomitant administration of anabolic steroids (methandrostenolone) and this medicine, increases the plasma concentration of oxyphenbutazone.

Zolidime side effects

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Gastrointestinal tract:

Common: nausea, gas-tritis.

Occasional: gastrointestinal upset, heartburn, epigastric pain, peptic ulcer, diarrhea.

Rare: vomiting, gastrointestinal bleeding (hematemesis and / or melena), bleeding or perforation of peptic ulcers.

In isolated cases: pancreatitis, esophagitis, esophageal ulcer, benign esophageal narrowing, exacerbation of inflammatory bowel disease, including Crohn’s disease with bleeding, ulceration or perforation, small bowel obstruction, constipation.

Zolidime contraindications

this medicine is contraindicated in patients with hypersensitivity to pyrazolones Phenylbutazone (Zolidime) and other derivatives, with obvious gastric ulcer or a history of it, with symptoms or history of inflammatory bowel disease with or without ulceration, blood dyscrasias, or history of them, bleeding diathesis ( thrombocytopenia, coagulation disorders), severe heart failure, liver or kidney disease, severe hypertension, thyroid disease, Sjogren’s syndrome. this medicine is also contraindicated in asthmatic patients in which the making of salicylic acid or other drugs with inhibitory activity of prostaglandin synthetase triggers asthma attacks, urticaria, acute rhinitis or other manifestations of hypersensitivity.


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Active ingredient matches for Zolidime:

Aspirin/Dexamethasone/Phenylbutazone in Mexico.

Aspirin/Dexamethasone Sodium Phosphate/Phenylbutazone


List of Zolidime substitutes (brand and generic names)

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References

  1. DailyMed. "PHENYLBUTAZONE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "DEXAMETHASONE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. DailyMed. "ASPIRIN; DIPYRIDAMOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Zolidime are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Zolidime. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


Consumer reported price estimates

No survey data has been collected yet


4 consumers reported time for results

To what extent do I have to use Zolidime before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 1 day and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Zolidime. To get the time effectiveness of using Zolidime drug by other patients, please click here.
Users%
1 day2
50.0%
1 month1
25.0%
1 week1
25.0%


18 consumers reported age

Users%
30-457
38.9%
46-605
27.8%
16-293
16.7%
> 603
16.7%


Consumer reviews


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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