Ambroxol HCl indications
Treatment of acute respiratory tract diseases with impaired formation of secretions, particularly in acute exacerbations of chronic and asthmatic bronchitis, bronchial asthma and bronchiectasis.
Treatment of respiratory disorders associated with viscid mucus eg, pneumonia, otitis media, sinusitis, nasopharyngitis.
As secretolytic therapy for relieving cough in acute and chronic disorders of the respiratory tract associated with pathologically thickened mucus and impaired mucus transport.
Uses of Ambroxol HCl in details
Ambroxol HCl is used to treat certain diseases of the respiratory tract and to relieve cough associated with thickened mucous.
Ambroxol HCl description
Each tablet also contains maize starch, dibasic calcium phosphate, anhydrous microcrystalline cellulose, talc, magnesium stearate and colloidal silicon dioxide as excipients.
Each 5 mL of syrup also contains granulated sucrose, sorbitol 70%, methylparahydroxybenzoate, propylparahydroxybenzoate, sodium benzoate, citric acid monohydrate, propylene glycol, disodium edentate, thiourea, menthol, blackcurrant flavor, soluble ponceu 4R, purified water (15 mg/5 mL pediatric syrup) or deionized water (30 mg/5 mL syrup) as excipients.
Each mL of oral drops also contains granulated sucrose, sorbitol 70%, methylparahydroxybenzoate, propylparahydroxybenzoate, sodium benzoate, citric acid monohydrate, propylene glycol, disodium edentate, thiourea, menthol, blackcurrant flavor, soluble ponceu 4R, purified water as excipients.
Each SR capsule also contains sucrose microgranules, maize starch microgranules, methacrylic acid-methyl methacrylate copolymer 1:1 (Eudragit L100), diethyl phthalate and talc as excipients.
Ambroxol HCl dosage
Adult: Tablet: 1 tablet 3 times daily. The tablet should be taken after a meal with adequate fluid.
Syrup: 5 mL of 30 mg/5 mL syrup 3 times daily. The syrup should be taken with food.
Pediatric Syrup: 10 mL of 15 mg/5 mL syrup 2-3 times daily. In severe cases, the dose may be increased up to 20 mL 2 times daily.
SR Capsule: 1 capsule daily. The capsule should be swallowed whole without chewing after a meal with adequate fluid.
Children: Recommended Daily Dose: 1.2-1.6 mg/kg body weight; 6-11 years: Tablet: ½ tablet 3 times daily. Pediatric Syrup: 5 mL 3 times daily; 2-5 years: Pediatric Syrup: 2.5 mL 3 times daily.
Oral Drops:
10-20 drops 3 times daily; <2 years (only when prescribed by a doctor): Pediatric Syrup: 2.5 mL 2 times daily.Oral Drops:
5-10 drops 3 times daily.Double strength syrup is for initial treatment; the dosage may be halved after 14 days.
Initial Treatment: Syrup: Adult and Children >12 years: 5 mL 3 times daily. Children 6-12 years: 5 mL 2-3 times daily; 2-6 years: 2.5 mL 3 times daily; 1-2 years: 2.5 mL 2 times daily.
Treatment Continuation: Pediatric Syrup: Children 6-12 years: 5 mL 2-3 times daily; 2-6 years: 2.5 mL 3 times daily; 1-2 years: 2.5 mL 2 times daily.
Elderly: There are no relevant data available.
Renal Impairment: In severe renal impairment, Ambroxol HCl must only be used under medical supervision; maintenance therapy should be reduced or the dosing interval extended. The secretolytic effect of Ambroxol HCl is supported by adequate fluid intake.
Hepatic Impairment: In severe hepatic impairment, Ambroxol HCl must only be used under medical supervision.
Ambroxol HCl interactions
Antitussives: Concomitant administration of antitussives may impair the expectoration of liquefied bronchial mucus due to inhibition of cough reflex and cause congestion of secretions.
Antibiotics: After using Ambroxol HCl, the concentrations of the antibiotics amoxicillin, cefuroxime and erythromycin in bronchial secretions and sputum are increased.
Ambroxol HCl side effects
Clinical Trial Data: Not relevant for Ambroxol HCl.
Post-Marketing Data: Adverse reactions are ranked under headings of frequency using the following convention: Very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1000 to <1/100); rare (≥1/10,000 to <1/1000); very rare (<1/10,000); not known (cannot be estimated from the available data).
Immune System Disorders : Not Known: Allergic reactions, anaphylactic reactions including anaphylactic shock.
Nervous System Disorders: Common: Dysgeusia* (eg, altered flavors).
Gastrointestinal Disorders: Common: Nausea, oral and pharyngeal hypoesthesia*. Uncommon: Diarrhea, vomiting, dyspepsia, abdominal pain, dry mouth*. Not Known: Dry throat*.
Skin and Subcutaneous Tissue Disorders: Rare: Rash, urticaria. Now Known: Pruritus, angioedema.
*Adverse events have been reported only after syrup use.
Ambroxol HCl contraindications
Hypersensitivity to Ambroxol HCl or to bromhexine, or to any of the constituents of Panacough Expectorant Extra.
Should not be taken simultaneously with antitussives (eg, codeine) because phlegm, which has been liquified by Ambroxol HCl, might not be expectorated.
Active ingredient matches for Ambroxol HCl:
Ambroxol HCl
| Unit description / dosage (Manufacturer) | Price, USD |
| Ambroxol HCl 30 mg x 10 Blister x 10 Tablet | |
| Ambroxol HCl 30 mg x 1 Bottle 100 Tablet | |
List of Ambroxol HCl substitutes (brand and generic names): | |
| Ambroxol-medico 30 | |
| Ambroxyl 15 | |
| Amsolvon (Taiwan) | |
| Amsolvon 30 mg x 1000's | |
| Amsolvon 75 mg x 1000's | |
| Amsolyn (Vietnam) | |
| Amsolyn 30 mg x 1 Bottle 100 Tablet | |
| Amtuss Syrup (Malaysia) | |
| Amtuss Syrup 30 mg/5 mL x 60 mL | |
| Amxol 安素 (Hongkong) | |
| Amxol tab 30 mg 10 x 10's (Biolab) | |
| Anfloxol (Philippines) | |
| Axomus (Vietnam) | |
| Axomus 30 mg x 2 Blister x 10 Tablet | |
| Axomus 30 mg x 10 Blister x 10 Tablet | |
| Bromace (Philippines) | |
| Bromace 6 mg/1 mL x 15 mL (Ace) | |
| Bromace 15 mg/5 mL x 60 mL (Ace) | |
| Bromace 30 mg/5 mL x 60 mL (Ace) | |
| Broxil-M (Philippines) | |
| Broxil-M 30 mg x 100's (Metz) | $ 13.33 |
| Broxil-M 15 mg/5 mL x 60 mL (Metz) | $ 1.47 |
| Chutan (Taiwan) | |
| Chutan 75 mg | |
| Dr Rentschler Hustenloser (Czech Republic) | |
| Epexol/Epexol Forte (Indonesia) | |
| Exolpen (Philippines) | |
| Exolpen 30 mg x 100's (Integrated pharmaceutical) | $ 12.44 |
| Exolpen 15 mg/5 mL x 60 mL (Integrated pharmaceutical) | $ 1.09 |
| Exolpen 30 mg/5 mL x 60 mL (Integrated pharmaceutical) | $ 1.52 |
| Exolpen 7.5 mg/1.25 mL x 15 mL (Integrated pharmaceutical) | $ 1.07 |
| Expel Tablet/Expel Forte (Philippines) | |
| Jomatab (Vietnam) | |
| Jomatab 30 mg x 1 Bottle 100 Tablet | |
| Lafayette Ambroxol Hydrochloride (Philippines) | |
| Lafayette Ambroxol Hydrochloride 30 mg/5 mL x 60 mL | $ 0.37 |
| Lafayette Ambroxol Hydrochloride 15 mg/5 mL x 60 mL | |
| Max 化痰寶 (Hongkong) | |
| Max tab 30 mg 1000's (Unison) | |
| Max tab 30 mg 50 x 10's (Unison) | |
| Mucopect/Mucopect Retard (Indonesia) | |
| Mucosolvan 24 Hours (Singapore) | |
| Mucosolvan 24 Hours 75 mg x 10's (Boehringer Ingelheim) | $ 5.29 |
| Mucosolvan 24 Hours 75 mg x 50's (Boehringer Ingelheim) | $ 24.14 |
| Mucosolvan 24 Hours cap 75 mg 10's (Boehringer Ingelheim) | |
| Mucosolvan 24 Hours cap 75 mg 50's (Boehringer Ingelheim) | |
| Mucosolvan 24 Hours MR cap 75 mg 10's (Boehringer Ingelheim) | |
| Mucosolvan 沐舒痰 (Hongkong) | |
| Mucosolvan tab 30 mg 50's (Boehringer Ingelheim) | |
| Mucosolvan/Mucosolvan PL (Thailand) | |
| Mucosolvan oral liqd 30 mg/5 mL 60 mL x 1's (Boehringer Ingelheim) | |
| Mucosolvan oral liqd 30 mg/5 mL 60 mL x 25 x 1's (Boehringer Ingelheim) | |
| Mucosolvan PL retard cap 75 mg 50's (Boehringer Ingelheim) | |
| Mucosolvan tab 30 mg 50 x 10's (Boehringer Ingelheim) | |
| Myracof Tablet (Philippines) | |
| Naroxol (Vietnam) | |
| Naroxol 30 mg x 2 Blister x 10 Tablet | |
| Naroxol 30 mg x 10 Blister x 10 Tablet | |
See 88 substitutes for Ambroxol HCl | |
References
- PubChem. "ambroxol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "ambroxol". http://www.drugbank.ca/drugs/DB06742 (accessed September 17, 2018).
- MeSH. "Expectorants". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Ambroxol HCl are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Ambroxol HCl. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
1 consumer reported useful
Was the Ambroxol HCl drug useful in terms of decreasing the symptom or the disease?According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
| Users | % | ||
|---|---|---|---|
| Not useful | 1 | 100.0% | |
1 consumer reported price estimates
Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?The below mentioned numbers have been reported by ndrugs.com website users about whether the Ambroxol HCl drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
| Users | % | ||
|---|---|---|---|
| Not expensive | 1 | 100.0% | |
3 consumers reported time for results
To what extent do I have to use Ambroxol HCl before I begin to see changes in my health conditions?As part of the reports released by ndrugs.com website users, it takes 5 days and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Ambroxol HCl. To get the time effectiveness of using Ambroxol HCl drug by other patients, please click here.
| Users | % | ||
|---|---|---|---|
| 5 days | 1 | 33.3% | |
| 1 week | 1 | 33.3% | |
| 1 day | 1 | 33.3% | |
8 consumers reported age
| Users | % | ||
|---|---|---|---|
| 16-29 | 4 | 50.0% | |
| 1-5 | 1 | 12.5% | |
| 46-60 | 1 | 12.5% | |
| < 1 | 1 | 12.5% | |
| 6-15 | 1 | 12.5% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
