Amsolvon indications
Treatment of acute respiratory tract diseases with impaired formation of secretions, particularly in acute exacerbations of chronic and asthmatic bronchitis, bronchial asthma and bronchiectasis.
Treatment of respiratory disorders associated with viscid mucus eg, pneumonia, otitis media, sinusitis, nasopharyngitis.
As secretolytic therapy for relieving cough in acute and chronic disorders of the respiratory tract associated with pathologically thickened mucus and impaired mucus transport.
Uses of Amsolvon in details
Amsolvon is used to treat certain diseases of the respiratory tract and to relieve cough associated with thickened mucous.
Amsolvon description
Each tablet also contains maize starch, dibasic calcium phosphate, anhydrous microcrystalline cellulose, talc, magnesium stearate and colloidal silicon dioxide as excipients.
Each 5 mL of syrup also contains granulated sucrose, sorbitol 70%, methylparahydroxybenzoate, propylparahydroxybenzoate, sodium benzoate, citric acid monohydrate, propylene glycol, disodium edentate, thiourea, menthol, blackcurrant flavor, soluble ponceu 4R, purified water (15 mg/5 mL pediatric syrup) or deionized water (30 mg/5 mL syrup) as excipients.
Each mL of oral drops also contains granulated sucrose, sorbitol 70%, methylparahydroxybenzoate, propylparahydroxybenzoate, sodium benzoate, citric acid monohydrate, propylene glycol, disodium edentate, thiourea, menthol, blackcurrant flavor, soluble ponceu 4R, purified water as excipients.
Each SR capsule also contains sucrose microgranules, maize starch microgranules, methacrylic acid-methyl methacrylate copolymer 1:1 (Eudragit L100), diethyl phthalate and talc as excipients.
Amsolvon dosage
Adult: Tablet: 1 tablet 3 times daily. The tablet should be taken after a meal with adequate fluid.
Syrup: 5 mL of 30 mg/5 mL syrup 3 times daily. The syrup should be taken with food.
Pediatric Syrup: 10 mL of 15 mg/5 mL syrup 2-3 times daily. In severe cases, the dose may be increased up to 20 mL 2 times daily.
SR Capsule: 1 capsule daily. The capsule should be swallowed whole without chewing after a meal with adequate fluid.
Children: Recommended Daily Dose: 1.2-1.6 mg/kg body weight; 6-11 years: Tablet: ½ tablet 3 times daily. Pediatric Syrup: 5 mL 3 times daily; 2-5 years: Pediatric Syrup: 2.5 mL 3 times daily.
Oral Drops:
10-20 drops 3 times daily; <2 years (only when prescribed by a doctor): Pediatric Syrup: 2.5 mL 2 times daily.Oral Drops:
5-10 drops 3 times daily.Double strength syrup is for initial treatment; the dosage may be halved after 14 days.
Initial Treatment: Syrup: Adult and Children >12 years: 5 mL 3 times daily. Children 6-12 years: 5 mL 2-3 times daily; 2-6 years: 2.5 mL 3 times daily; 1-2 years: 2.5 mL 2 times daily.
Treatment Continuation: Pediatric Syrup: Children 6-12 years: 5 mL 2-3 times daily; 2-6 years: 2.5 mL 3 times daily; 1-2 years: 2.5 mL 2 times daily.
Elderly: There are no relevant data available.
Renal Impairment: In severe renal impairment, Amsolvon must only be used under medical supervision; maintenance therapy should be reduced or the dosing interval extended. The secretolytic effect of Amsolvon is supported by adequate fluid intake.
Hepatic Impairment: In severe hepatic impairment, Amsolvon must only be used under medical supervision.
Amsolvon interactions
Antitussives: Concomitant administration of antitussives may impair the expectoration of liquefied bronchial mucus due to inhibition of cough reflex and cause congestion of secretions.
Antibiotics: After using Amsolvon, the concentrations of the antibiotics amoxicillin, cefuroxime and erythromycin in bronchial secretions and sputum are increased.
Amsolvon side effects
Clinical Trial Data: Not relevant for Amsolvon.
Post-Marketing Data: Adverse reactions are ranked under headings of frequency using the following convention: Very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1000 to <1/100); rare (≥1/10,000 to <1/1000); very rare (<1/10,000); not known (cannot be estimated from the available data).
Immune System Disorders : Not Known: Allergic reactions, anaphylactic reactions including anaphylactic shock.
Nervous System Disorders: Common: Dysgeusia* (eg, altered flavors).
Gastrointestinal Disorders: Common: Nausea, oral and pharyngeal hypoesthesia*. Uncommon: Diarrhea, vomiting, dyspepsia, abdominal pain, dry mouth*. Not Known: Dry throat*.
Skin and Subcutaneous Tissue Disorders: Rare: Rash, urticaria. Now Known: Pruritus, angioedema.
*Adverse events have been reported only after syrup use.
Amsolvon contraindications
Hypersensitivity to Amsolvon or to bromhexine, or to any of the constituents of Panacough Expectorant Extra.
Should not be taken simultaneously with antitussives (eg, codeine) because phlegm, which has been liquified by Amsolvon, might not be expectorated.
Active ingredient matches for Amsolvon:
Ambroxol HCl in Taiwan.
| Unit description / dosage (Manufacturer) | Price, USD |
| Amsolvon 30 mg x 1000's | |
| Amsolvon 75 mg x 1000's | |
List of Amsolvon substitutes (brand and generic names): | |
| Ambroxyl 15 | |
| Amsolyn (Vietnam) | |
| Amsolyn 30 mg x 1 Bottle 100 Tablet | |
| Amtuss Syrup (Malaysia) | |
| Amtuss Syrup 30 mg/5 mL x 60 mL | |
| Amxol 安素 (Hongkong) | |
| Amxol tab 30 mg 10 x 10's (Biolab) | |
| Anfloxol (Philippines) | |
| Axomus (Vietnam) | |
| Axomus 30 mg x 2 Blister x 10 Tablet | |
| Axomus 30 mg x 10 Blister x 10 Tablet | |
| Bromace (Philippines) | |
| Bromace 6 mg/1 mL x 15 mL (Ace) | |
| Bromace 15 mg/5 mL x 60 mL (Ace) | |
| Bromace 30 mg/5 mL x 60 mL (Ace) | |
| Broxil-M (Philippines) | |
| Broxil-M 30 mg x 100's (Metz) | $ 13.33 |
| Broxil-M 15 mg/5 mL x 60 mL (Metz) | $ 1.47 |
| Chutan (Taiwan) | |
| Chutan 75 mg | |
| Dr Rentschler Hustenloser (Czech Republic) | |
| Epexol/Epexol Forte (Indonesia) | |
| Exolpen (Philippines) | |
| Exolpen 30 mg x 100's (Integrated pharmaceutical) | $ 12.44 |
| Exolpen 15 mg/5 mL x 60 mL (Integrated pharmaceutical) | $ 1.09 |
| Exolpen 30 mg/5 mL x 60 mL (Integrated pharmaceutical) | $ 1.52 |
| Exolpen 7.5 mg/1.25 mL x 15 mL (Integrated pharmaceutical) | $ 1.07 |
| Expel Tablet/Expel Forte (Philippines) | |
| Jomatab (Vietnam) | |
| Jomatab 30 mg x 1 Bottle 100 Tablet | |
| Lafayette Ambroxol Hydrochloride (Philippines) | |
| Lafayette Ambroxol Hydrochloride 30 mg/5 mL x 60 mL | $ 0.37 |
| Lafayette Ambroxol Hydrochloride 15 mg/5 mL x 60 mL | |
| Max 化痰寶 (Hongkong) | |
| Max tab 30 mg 1000's (Unison) | |
| Max tab 30 mg 50 x 10's (Unison) | |
| Mucopect/Mucopect Retard (Indonesia) | |
| Mucosolvan 24 Hours (Singapore) | |
| Mucosolvan 24 Hours 75 mg x 10's (Boehringer Ingelheim) | $ 5.29 |
| Mucosolvan 24 Hours 75 mg x 50's (Boehringer Ingelheim) | $ 24.14 |
| Mucosolvan 24 Hours cap 75 mg 10's (Boehringer Ingelheim) | |
| Mucosolvan 24 Hours cap 75 mg 50's (Boehringer Ingelheim) | |
| Mucosolvan 24 Hours MR cap 75 mg 10's (Boehringer Ingelheim) | |
| Mucosolvan 沐舒痰 (Hongkong) | |
| Mucosolvan tab 30 mg 50's (Boehringer Ingelheim) | |
| Mucosolvan/Mucosolvan PL (Thailand) | |
| Mucosolvan oral liqd 30 mg/5 mL 60 mL x 1's (Boehringer Ingelheim) | |
| Mucosolvan oral liqd 30 mg/5 mL 60 mL x 25 x 1's (Boehringer Ingelheim) | |
| Mucosolvan PL retard cap 75 mg 50's (Boehringer Ingelheim) | |
| Mucosolvan tab 30 mg 50 x 10's (Boehringer Ingelheim) | |
| Myracof Tablet (Philippines) | |
| Naroxol (Vietnam) | |
| Naroxol 30 mg x 2 Blister x 10 Tablet | |
| Naroxol 30 mg x 10 Blister x 10 Tablet | |
| Naroxol 30 mg x 3 Blister x 30 Tablet | |
| Obroxol (Hongkong) | |
| Panacough Expectorant Extra 必理咳化痰止咳丸特強 (Hongkong) | |
| Panacough Expectorant Extra SR cap 75 mg 10's (GSK Consumer) | |
See 88 substitutes for Amsolvon | |
References
- PubChem. "ambroxol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "ambroxol". http://www.drugbank.ca/drugs/DB06742 (accessed September 17, 2018).
- MeSH. "Expectorants". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Amsolvon are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Amsolvon. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yet1 consumer reported age
| Users | % | ||
|---|---|---|---|
| 46-60 | 1 | 100.0% | |
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Information checked by Dr. Sachin Kumar, MD Pharmacology
