Clobetasol topical Uses

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What is Clobetasol topical?

Clobetasol topical lotion is a prescription corticosteroid medicine used on the skin (topical) for the relief of swelling (inflammation) and itching caused by certain skin conditions in people 18 years of age and older.

Clobetasol topical lotion should not be used for the treatment of acne vulgaris, rosacea or red, dry itchy skin (dermatitis) around the mouth.

Clobetasol topical lotion is not recommended in children under 18 years of age.

Important: Clobetasol topical lotion is for use on the skin only. Do not get the lotion near or in your eyes, mouth or vagina.

Clobetasol topical indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Indication

Clobetasol topical® Spray, 0.05% is a super-high potent topical corticosteroid formulation indicated for the treatment of moderate to severe plaque psoriasis affecting up to 20% body surface area (BSA) in patients 18 years of age or older. The total dosage should not exceed 50 g (59 mL or 2 fl. oz.) per week. Do not use more than 26 sprays per application or 52 sprays per day. Treatment should be limited to 4 consecutive weeks.

Patients should be instructed to use Clobetasol topical® Spray, 0.05% for the minimum amount of time necessary to achieve the desired results see [Dosage and Administration (2)].

Use in patients under 18 years of age is not recommended because safety has not been established and because numerically high rates of HPA axis suppression were seen with other clobetasol propionate topical formulations.

Limitations of Use

Clobetasol topical® Spray, 0.05% should not be used on the face, axillae, or groin. Clobetasol topical® Spray, 0.05% should not be used if there is atrophy at the treatment site. Clobetasol topical® Spray, 0.05% should not be used in the treatment of rosacea or perioral dermatitis.

How should I use Clobetasol topical?

Use Clobetasol topical as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Clobetasol topical.

Uses of Clobetasol topical in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Clobetasol topical is used to treat itching, redness, dryness, inflammation, and discomfort of various scalp and skin conditions, including immune-mediated skin disease with red scaly patches (psoriasis).

Clobetasol topical description

Clobetasol topical scalp application also contains the following excipients: Carbomer, isopropyl alcohol, sodium hydroxide and purified water.

Clobetasol topical cream also contains the following excipients: Glyceryl monostearate, cetostearyl alcohol, chlorocresol, sodium citrate, monohydrated citric acid, purified water, Arlacel 165, beeswax substitute 6621 and propylene glycol.

Clobetasol topical ointment also contains the following excipients: Propylene glycol, white soft paraffin and sorbitan sesquioleate.

Clobetasol topical dosage

Clobetasol topical Dosage

Generic name: clobetasol propionate 0.5mg in 1g

Dosage form: cream, ointment

See also:

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Apply a thin layer of Clobetasol topical® Cream or Ointment to the affected skin areas twice daily and rub in gently and completely.

Clobetasol topical® Cream and Ointment are super-high potency topical corti-costeroids; therefore, treatment should be limited to 2 consecutive weeks and amounts greater than 50 g/week should not be used.

As with other highly active corticosteroids, therapy should be discontinued when control has been achieved. If no improvement is seen within 2 weeks, reassessment of diagnosis may be necessary.

Clobetasol topical® Cream and Ointment should not be used with occlusive dressings.

Geriatric Use: In studies where geriatric patients (65 years of age or older, see PRECAUTIONS) have been treated with Clobetasol topical® Cream or Ointment, safety did not differ from that in younger patients; therefore, no dosage adjustment is recommended.

More about Clobetasol topical (Clobetasol topical)

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Professional resources

Other formulations

Related treatment guides

Clobetasol topical interactions

See also:
What other drugs will affect Clobetasol topical?

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Aldesleukin: Corticosteroids may diminish the antineoplastic effect of Aldesleukin. Avoid combination

Corticorelin: Corticosteroids may diminish the therapeutic effect of Corticorelin. Specifically, the plasma ACTH response to corticorelin may be blunted by recent or current corticosteroid therapy. Monitor therapy

Deferasirox: Corticosteroids may enhance the adverse/toxic effect of Deferasirox. Specifically, the risk for GI ulceration/irritation or GI bleeding may be increased. Monitor therapy

Hyaluronidase: Corticosteroids may diminish the therapeutic effect of Hyaluronidase. Management: Patients receiving corticosteroids (particularly at larger doses) may not experience the desired clinical response to standard doses of hyaluronidase. Larger doses of hyaluronidase may be required. Consider therapy modification

Ritodrine: Corticosteroids may enhance the adverse/toxic effect of Ritodrine. Monitor therapy

Clobetasol topical side effects

See also:
What are the possible side effects of Clobetasol topical?

Applies to Clobetasol topical: topical application cream, topical application emollient cream, topical application foam, topical application gel/jelly, topical application lotion, topical application ointment, topical application shampoo, topical application solution, topical application spray

As well as its needed effects, Clobetasol topical (the active ingredient contained in Clobetasol topical) may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking Clobetasol topical, check with your doctor immediately:

More common:

Less common: Incidence not known:

Minor Side Effects

Some Clobetasol topical side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common:

Less common: Incidence not known:

Clobetasol topical contraindications

See also:
What is the most important information I should know about Clobetasol topical?

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Hypersensitivity to clobetasol propionate or to any of the excipients of Clobetasol topical.

Scalp Application: Infections of the scalp.

Cream/Ointment: Primary skin lesions caused by infection with fungi or bacteria; primary cutaneous viral infections (eg, herpes simplex, chickenpox); rosacea; acne vulgaris; pruritus without inflammation; perianal and genital pruritus; perioral dermatitis.

Use in children: Clobetasol topical is contraindicated in children <1 year.

Children are more likely to develop local and systemic side effects of topical corticosteroids and in general, require shorter courses and less potent agents than adults.

Care should be taken when using Clobetasol topical to ensure the amount applied is the minimum that provides therapeutic benefit.

Active ingredient matches for Clobetasol topical:

Clobetasol topical


List of Clobetasol topical substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Clobetaz 0.05% Cream (Forman Medics Pvt Ltd)$ 0.97
Clobetaz S Ointment (Forman Medics Pvt Ltd)$ 0.05
Spray; Topical; Clobetasol Propionate 0.05% (Galderma)
Clobex 0.05 % x 60 mL (Galderma)$ 143.00
Clobex 0.05 % x 118 mL (Galderma)$ 31.11
Clobex 0.05 % x 60 mL x 1's (Galderma)
Clobex 0.05 % x 125 mL (Galderma)
118 milliliter in 1 bottle (Galderma)
Shampoo; Topical; Clobetasol Propionate 0.05% (Galderma)
CLOBEX 10MG TABLET 1 strip / 10 tablets each (Galderma)$ 1.16
CLOBEX 5MG TABLET 1 strip / 10 tablets each (Galderma)$ 0.65
Clobex shampoo 0.05% 60 mL x 1's (Galderma)$ 30.96
Clobex shampoo 0.05 % 60 mL x 1's (Galderma)
Clobex shampoo 0.05 % 118 mL x 1's (Galderma)
Clobex shampoo .05 g/100mL (Galderma)
Clobex lotion .05 g/100mL (Galderma)
Clobex spray .5 mg/mL (Galderma)
Clobex spray .05 g/mL (Galderma)
Clobex lotion .05 mL/100mL (Galderma)
Clobex 10mg Tablet (Galderma)$ 0.12
Clobex 5mg Tablet (Galderma)$ 0.07
Lotion; Topical; Clobetasol Propionate 0.05%
Clobex Lotion lotion 0.05 % (Galderma Canada Inc (Canada))
Shampoo; Topical; Clobetasol Propionate 0.05%
Clobex Shampoo shampoo 0.05 % (Galderma Canada Inc (Canada))
Solution; Topical; Clobetasol Propionate 0.05%
Clobex Spray solution 0.05 % (Galderma Canada Inc (Canada))
CLOBKARE-XL CREAM 0.05% W/W CREAM 1 tube / 30 GM cream each (Dermakare Pharmaceuticals Pvt Ltd)$ 1.98
Clodan shampoo .5 mg/mL (Medimetriks Pharmaceuticals (US))
CLODERM / KINESES CREAM 1 tube / 15 GM cream each (Kineses Laboratories)$ 0.83
CLOLITE-ZE CREAM 1 tube / 30 GM cream each (La Med India)$ 1.46
CLOMIGHT CREAM 1 tube / 15 GM cream each (Mac Remedies Pvt Ltd)$ 0.61
Clonext NA Cream (Ethinext Pharma)$ 1.43
CLONIT CREAM 1 tube / 15 GM cream each (Karlin Pharmaceuticals & Exports Pvt Ltd)$ 0.54
CLOPAD CREAM 1 tube / 30 GM cream each (Tripada Biotec Pvt Ltd)$ 1.27
CLOPINATE 0.05% W/W CREAM 1 tube / 30 GM cream each (Monichem Healthcare Pvt Ltd)$ 1.21
CLOPINATE 0.05% W/W CREAM 1 tube / 15 GM cream each (Monichem Healthcare Pvt Ltd)$ 0.76

References

  1. PubChem. "clobetasol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Clobetasol". http://www.drugbank.ca/drugs/DB11750 (accessed September 17, 2018).
  3. MeSH. "Glucocorticoids". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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